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sniffin sticks

A Oleszkiewicz, V A Schriever, I Croy, A Hähner, Thomas Hummel
PURPOSE: To provide up-to-date and detailed normative data based on a large-scale sample, increasing diagnostic validity by reference to narrow age groups as previous normative values were based upon smaller sample sizes-especially in the group of older subjects. METHOD: Data were obtained from 9139 healthy subjects (4928 females aged 5-96 years and 4211 males aged 5-91 years). The standard "Sniffin' Sticks" test was applied, comprising threshold (T), discrimination (D) and identification (I) subtests, and yielding a TDI sum score...
December 15, 2018: European Archives of Oto-rhino-laryngology
Massimiliano Garzaro, Giancarlo Pecorari, Giuseppe Riva, Valentina Pennacchietti, Paolo Pacca, Luca Raimondo, Eleonora Tron, Alessandro Ducati, Francesco Zenga
OBJECTIVES: Endoscopic transnasal transsphenoidal surgery has become the standard procedure for the majority of skull base diseases, including sellar, parasellar, and clival pathologies. The aim of this study was the objective evaluation of nasal airflow resistances and olfactory function in 3-dimensional (3D) endoscopic transnasal transsphenoidal surgery. METHODS: One hundred patients who underwent 3D transnasal endoscopic surgery for sellar, parasellar, and clival diseases were enrolled...
December 10, 2018: Annals of Otology, Rhinology, and Laryngology
Gerold Besser, Leandra Jobs, David Tianxiang Liu, Christian A Mueller, Bertold Renner
OBJECTIVES: Neurodegenerative diseases can alter odor memory in addition to inducing quantitative impairment, and olfactory memory can be tested using the validated olfactory memory test with encapsulated odors (Odor Discrimination Memory Test [ODMT]). The aim of this study was to investigate the new Sniffin' Sticks ODMT (SSODMT), which is comparable with the ODMT. METHODS: The SSODMT was administered to 48 subjects (30 women, 18 men; mean age, 34.6 ± 16.3 years)...
December 7, 2018: Annals of Otology, Rhinology, and Laryngology
Marlene Richter Jensen, Elisabeth Arndal, Christian Von Buchwald
The aim of this review is to evaluate current guidelines for diagnosis, treatment and follow-up of patients with chronic rhinosinusitis. We discuss: 1) diagnostic criteria, 2) the use of supplementary tools like visual analogue scale, Sino-Nasal Outcome Test and Sniffin' Sticks, 3) the use of tests like allergy, serum IgE and biopsy and 4) comorbidity in relation to the unified airways concept. Furthermore, we evaluate: 1) initial treatment with topical steroids and nasal irrigation, 2) additional treatment options including surgery, systemic steroids and antibiotics and 3) treatment risks...
November 19, 2018: Ugeskrift for Laeger
Luzia Jaeger Hintze, Gary Goldfield, Ryan Seguin, Aleck Damphousse, Alexandre Riopel, Éric Doucet
BACKGROUND: Evidence of metabolic adaptations following weight loss is available in the literature. However, the impact of different degrees of caloric restriction on a comprehensive panel including energy expenditure (EE) and intake (EI), appetite, palatability and olfactory performance remains to be investigated. Accordingly, the purpose of the study was to investigate the changes in resting energy expenditure (REE), appetite, olfaction, palatability and EI in women who were engaged in either a slow (-500 kcal/day, 20-week) or in a rapid (-1000 kcal/ day, 10 weeks) weight loss program...
November 26, 2018: Physiology & Behavior
Gabriel Bsteh, Klaus Berek, Harald Hegen, Barbara Teuchner, Michael Auer, Sebastian Wurth, Franziska Di Pauli, Florian Deisenhammer, Thomas Berger
BACKGROUND: Peripapillary retinal nerve fiber layer (pRNFL) thickness and olfactory function are both emerging biomarkers in multiple sclerosis (MS). Impairment of odor identification and discrimination is an irreversible feature of more advanced MS suggested to be associated with neurodegeneration, while olfactory threshold is a transient feature of early, active MS possibly associated with short-term inflammatory disease activity. OBJECTIVE: The aim of this study was to validate the association of olfactory (dys)function and parameters of MS disease course in a large cohort of MS patients and to correlate olfactory function with pRNFL thickness as a surrogate biomarker of neurodegeneration...
November 22, 2018: Multiple Sclerosis: Clinical and Laboratory Research
Andreas Hinz, Tobias Luck, Steffi G Riedel-Heller, Philipp Y Herzberg, Claudia Rolffs, Kerstin Wirkner, Christoph Engel
PURPOSE: The Sniffin' Sticks Screening 12 test is a test of olfactory performance based on pen-like odor dispensing devices. The aims of this study were to analyze the performance of this test in a general population sample and to explore associations between olfactory dysfunction and quality of life. METHODS: A large community sample (n = 7267) completed the Sniffin' Sticks Screening 12 test and several questionnaires measuring quality of life, anxiety, dispositional optimism, social support, and satisfaction with life...
November 20, 2018: European Archives of Oto-rhino-laryngology
X G Yan, X Gao, Z F Sun, Y C Guo, L Y Yao, J Liu, W Xiao, Q W Lyu, Y X Wei
Objective: To explore the clinical effects and the influence factors of olfactory training in the treatment of olfactory dysfunction. Methods: A total of 86 patients with olfactory dysfunction (49 post-infectious and 37 post-traumatic) in Beijing Anzhen Hospital during Dec 2016 to May 2017 were recruited in this prospective study. The clinical data of patients were analyzed, including gender, age, body mass index (BMI), course of disease, smoking history, drinking history, diabetes history, hypertension history, hyperlipidemia history, and anxiety visual analogue score (VAS)...
November 7, 2018: Zhonghua Er Bi Yan Hou Tou Jing Wai Ke za Zhi, Chinese Journal of Otorhinolaryngology Head and Neck Surgery
Mei Peng, Duncan Coutts, Ting Wang, Yusuf O Cakmak
OBJECTIVE: The modern food environment is a key driver of rising levels of obesity. While olfaction is known to play a major role in food choice; however, its relationship to obesity is yet to be understood. This review assesses current knowledge of the interaction between obesity and olfaction. METHODS: This review is based on observational studies comparing olfactory abilities across weight groups (N = 10) and clinical studies evaluating olfactory changes following bariatric surgery (N = 9)...
November 19, 2018: Obesity Reviews: An Official Journal of the International Association for the Study of Obesity
Soo-Jin Lee, Eun-Mi Kim, Seok-Hyun Cho, Jaechul Song, Tae-Won Jang, Mi-Young Lee
OBJECTIVES: The present study was performed to investigate the prevalence of olfactory dysfunction in workers exposed to hazardous substances in a variety of occupations in Korea. METHODS: We designed a cross-sectional study. The exposed group (n=296) consisted of Korean workers in the automobile repair, printing, shoemaking and plating industries and was compared with office workers (non-exposed group, n=99). A self-report questionnaire was administered to the subjects for demographic characteristics...
November 3, 2018: BMJ Open
Cinthia Terroba Chambi, Malco Rossi, Andrea Bril, Patricio Millar Vernetti, Daniel Cerquetti, Angel Cammarota, Marcelo Merello
Background: The diagnosis of Parkinson's disease (PD) can be challenging early in the disease course, when motor features are subtle. The objective of this study was to explore the diagnostic value of combining acute levodopa challenge and olfactory testing to predict PD. Methods: Data from 210 patients with a recent onset of parkinsonism who had at least 2 years of follow-up and underwent acute levodopa challenge for the clinical prediction of long-term dopaminergic response and had olfactory testing with Sniffin' Sticks Test were evaluated...
November 2017: Movement Disorders Clinical Practice
Jasmien Roosenboom, Robert Hermans, Frederik Lammens, Jean Louis Samain, Koen Devriendt, Vincent Vander Poorten, Peter W Hellings, Mark Jorissen, Hilde Peeters, Peter Claes, Greet Hens
Nonsyndromic orofacial clefting is one of the most frequently occurring congenital conditions. The aim of the study was to investigate the prevalence and nature of reduced olfactory function in patients with nonsyndromic cleft lip and/or cleft palate (NSCL/P) and their unaffected first-degree relatives. Olfactory function was tested using the Sniffin' Sticks identification test in patients with NSCL/P, in their unaffected relatives, and in control subjects. MR imaging was performed to measure olfactory bulb (OB) volumes and olfactory sulcus (OS) depths...
October 22, 2018: American Journal of Medical Genetics. Part A
Jolita Čičelienė, Žygimantas Vaičys, Daiva Rastenytė
Background : Evaluation of smell function is essential especially in cases of gradual deterioration, e.g., in neurodegenerative diseases, where rates of unawareness of the disorder are high and the importance of screening for olfactory dysfunction is increasing. To date, none of the tests for evaluation of olfactory dysfunction has been validated in Lithuania. The aim of the study was to develop a Lithuanian version of Sniffin' Sticks 12 (SS12) odor identification test. Materials and Methods : The study was performed in 4 stages...
April 11, 2018: Medicina
Hwa Reung Lee, Joong Hyun Park, Sang Won Han, Jong Sam Baik
OBJECTIVE: Cognitive impairment is one of the nonmotor symptoms in Parkinson's disease (PD), and olfactory dysfunction is used as a marker to detect premotor stages of PD. Serum uric acid (sUA) levels have been found to be a risk factor for PD. Our objective in this study was to examine whether sUA levels are associated with cognitive changes and olfactory dysfunction in early de novo PD patients. METHODS: The study participants included 196 de novo PD patients...
September 2018: Journal of Movement Disorders
Chenia Caldeira Martinez, Tássia Tonon, Tatiéle Nalin, Lilia Farret Refosco, Carolina Fischinger Moura de Souza, Ida Vanessa Doederlein Schwartz
Hepatic glycogen storage diseases (GSDs) are inborn errors of metabolism whose dietary treatment involves uncooked cornstarch administration and restriction of simple carbohydrate intake. The prevalence of feeding difficulties (FDs) and orofacial myofunctional disorders (OMDs) in these patients is unknown. OBJECTIVE: To ascertain the prevalence of FDs and OMDs in GSD. METHODS: This was a cross-sectional, prospective study of 36 patients (19 males; median age, 12...
September 22, 2018: JIMD Reports
G Magliulo, M De Vincentiis, G Iannella, A Ciofalo, B Pasquariello, A Manno, D Angeletti, A Polimeni
The sense of smell has a high impact on the quality of life. The aim of the present study was to investigate olfactory dysfunction in patients with obstructive sleep apnoea syndrome (OSAS) and correlate the severity of disease with olfactory dysfunction. The relationships between nasal obstruction, nasal mucociliary cleareance and olfactory tests were also evaluated. Sixty patients with a diagnosis of OSAS were enrolled and underwent olfactory function evaluation. In all patients olfactory performance was tested with the Sniffin' Sticks method...
August 2018: Acta Otorhinolaryngologica Italica
Gerold Besser, David T Liu, Bertold Renner, Thomas Hummel, Christian A Mueller
OBJECTIVES: Therapeutic options in olfactory dysfunction (OD) are limited. Numerous studies have shown impact of OD on quality of life. Lately, various studies support benefits of olfactory training, but therapy-refractory cases leave doctors and patients locked in a stalemate. An olfactory implant (OI), in analogy to the widely successful cochlear implant, still seems far away from realization. The present study sought to evaluate the demand of OI in patients with OD. METHODS: Sixty-one patients (28 females and 33 males, mean age/standard deviation 54...
August 25, 2018: Laryngoscope
Clemens Heiser, Bernhard Haller, Maximilian Sohn, Benedikt Hofauer, Andreas Knopf, Tobias Mühling, Jessica Freiherr, Martin Bender, Maximilian Tiller, Anna Schmidt, Wolfgang Schepp, Felix Gundling
INTRODUCTION AND AIM: Olfactory functions are altered to a variable degree by chronic liver disease. Few studies including only small populations of patients emphasized the possibility of hepatic encephalopathy (HE) influencing olfactory nervous tasks. So far, no study has explicitly focused on olfactory function depending on the severity of HE as assessed by objective diagnostic procedures. Thus we performed a study using the "Sniffin' Sticks" test system, critical flicker-fusion frequency (CFF) and clinical West Haven criteria...
August 24, 2018: Annals of Hepatology
Ji Eun Kim, Eungseok Oh, Jinse Park, Jinyoung Youn, Ji Sun Kim, Wooyoung Jang
The purpose of our study was to investigate the association between olfactory function in Parkinson's disease (PD) and serum vitamin D status. Thirty-nine patients with de novo PD were enrolled in this study. Olfactory function was assessed by an odor identification test, as a part of the KVSS (Korean version of sniffin' sticks) II test. All patients were also assessed with the NMSS (Non-Motor Symptoms Scale for PD) to check the subjective change in ability to smell. Vitamin D status was determined by measuring the level of serum 25-hydroxyvitamin D3 (25-OHD3)...
November 2018: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
Carlos Henrique Ferreira Camargo, Vinícius Aguiar Jobbins, Rafael Arthur Serpa, Frederico Antônio Berbetz, Jivago Szpoganicz Sabatini, Hélio Afonso Ghizoni Teive
OBJECTIVE: The aim of this study was to compare the cognitive deficits and olfaction in PD patients. PATIENTS AND METHODS: In all, 42 PD patients and 38 controls were selected. All the individuals in both groups underwent cognitive assessment with the SCOPA-Cog neuropsychological battery and Mini-Mental State Examination (MMSE) and olfactory assessment with the Sniffin' Sticks Screening 12 Test. Parkinson's disease dementia (PDD) was diagnosed using the International Parkinson and Movement Disorder Society (MDS) criteria...
October 2018: Clinical Neurology and Neurosurgery
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