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https://www.readbyqxmd.com/read/28690750/surgical-repair-of-a-pseudocoarctation-with-cervical-aortic-arch-complicated-by-multiple-aneurysms-of-the-aorta-a-case-report
#1
Said Makani, Julia Mitchell, Olivier Metton, Sylvie Di Filippo, Roland Henaine, Jean Ninet
Aortic pseudocoarctation is a rare congenital anomaly characterized by elongation and deformity of the aortic arch and is known to be associated with aneurysmal formation. Several studies unite to say it leads to a surgical sanction as soon as symptomatic or associated with aneurysms of the aortic arch. Our patient is a 12 years old boy, followed since birth for a little tight pseudocoarctation with a cervical aortic arch and transverse aortic arch hypoplasia. Close clinical and paraclinical monitoring including angioscans, showed the gradual enlargement of the superior mediastinum, in relation with the appearance of three aneurysms of the aortic arch...
2017: Pan African Medical Journal
https://www.readbyqxmd.com/read/28681751/assessment-of-surgical-risk-factors-in-the-development-of-ventilator-associated-pneumonia-in-neurosurgical-intensive-care-unit-patients-alarming-observations
#2
Deepashu Sachdeva, Daljit Singh, Poonam Loomba, Amandeep Kaur, Monica Tandon, Ishu Bishnoi
BACKGROUND: Ventilator-associated pneumonia (VAP) is the most frequent nosocomial infection in patients receiving mechanical ventilation (MV) and contributes to a longer intensive care unit (ICU) stay, duration of MV, and a high morbidity and mortality. OBJECTIVE: The purpose of study was to determine the incidence of VAP in neurosurgery ICU patients and to assess the probable contributing neurosurgical risk factors like the site and nature of the lesion in the brain, the duration of surgery, blood loss during surgery, and infection elsewhere in the body, in the development of VAP...
July 2017: Neurology India
https://www.readbyqxmd.com/read/28659059/endovascular-treatment-of-visceral-artery-aneurysms-and-pseudoaneurysms-in-100-patients-covered-stenting-vs-transcatheter-embolization
#3
Massimo Venturini, Paolo Marra, Michele Colombo, Marco Alparone, Giulia Agostini, Luca Bertoglio, Claudio Sallemi, Marco Salvioni, Simone Gusmini, Gianpaolo Balzano, Renata Castellano, Luca Aldrighetti, Yamume Tshomba, Massimo Falconi, Germano Melissano, Francesco De Cobelli, Roberto Chiesa, Alessandro Del Maschio
PURPOSE: To retrospectively report a large single-center experience of visceral artery aneurysms (VAAs) and pseudoaneurysms (VAPAs) treated with covered stenting (CS) as the first therapeutic option vs transcatheter embolization (TE). METHODS: One hundred patients (mean age 59±14 years; 58 men) underwent 59 elective and 41 emergent endovascular procedures to treat 51 VAAs and 49 VAPAs. Seventy patients had TE and 30 received CS (27 Viabahn and 3 coronary stent grafts)...
June 1, 2017: Journal of Endovascular Therapy
https://www.readbyqxmd.com/read/28500602/a-new-mouse-model-for-introduction-of-aortic-aneurysm-by-implantation-of-deoxycorticosterone-acetate-pellets-or-aldosterone-infusion-in-the-presence-of-high-salt
#4
Shu Liu, Ming C Gong, Zhenheng Guo
Dysfunction of the renin-angiotensin-aldosterone system (RAAS) has been implicated in the etiologies of many cardiovascular diseases, including aortic aneurysm. In particular, the infusion of angiotensin II (Ang II) in the apolipoprotein E-deficient mice (apoE-/-) and low density lipoprotein receptor knockout mice (LDLR-/-) to induce aortic aneurysm has been extensively used in the field. In contrast, whether aldosterone (Aldo), an essential component of RAAS and a downstream effector of Ang II, is involved in aortic aneurysm is largely unknown...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/28472526/glycoprotein-iib-iiia-inhibitors-in-prevention-and-rescue-treatment-of-thromboembolic-complications-during-endovascular-embolization-of-intracranial-aneurysms
#5
David Dornbos, Joel S Katz, Patrick Youssef, Ciarán J Powers, Shahid M Nimjee
Thromboembolic complications remain a major risk of endovascular neurosurgery during the treatment of intracranial aneurysms, despite the use of therapeutic heparinization and oral antiplatelet therapy when indicated. Glycoprotein (GP) IIb/IIIa inhibitors target a nonredundant pathway of platelet aggregation following adhesion and activation. Initially established and implemented in the cardiovascular arena, this drug class has provided a new tool in the neurovascular armamentarium as well. Numerous case reports, case series, and retrospective reviews have evaluated the safety and efficacy of abciximab, eptifibatide, and tirofiban in the treatment of acute thromboembolic complications during the endovascular treatment of intracranial aneurysms...
March 1, 2018: Neurosurgery
https://www.readbyqxmd.com/read/28438894/flow-diverter-treatment-of-intracranial-vertebral-artery-dissecting-pseudoaneurysms
#6
REVIEW
Russell Cerejo, Mark Bain, Nina Moore, Julian Hardman, Andrew Bauer, M Shazam Hussain, Thomas Masaryk, Peter Rasmussen, Gabor Toth
INTRODUCTION: Intracranial vertebral dissecting pseudoaneurysms are a rare, but increasingly recognized, cause of subarachnoid hemorrhage and ischemic stroke. The risks of aneurysm re-rupture and associated morbidity are high. The use of flow diverter stents for the treatment of these aneurysms has not been well studied. OBJECTIVE: To report our data and provide a summarized review of literature using flow diverter stents for the treatment of intracranial vertebral artery dissecting pseudoaneurysms...
November 2017: Journal of Neurointerventional Surgery
https://www.readbyqxmd.com/read/28377878/miliary-tuberculosis-in-a-patient-with-tuberculous-mycotic-aneurysm-of-the-abdominal-aorta-case-report-and-review-of-the-literature
#7
Katerina Manika, Christoforos Efthymiou, Georgios Damianidis, Elisavet Zioga, Eleni Papadaki, Kalliopi Lagoudi, Ioannis Kioumis
The combination of miliary tuberculosis and tuberculous mycotic aneurysm has been described in the literature. We present the case of an 84-year-old man who was diagnosed with a mycotic aneurysm of the abdominal aorta and an adjacent soft tissue mass, after a 3- month history of fever. The patient underwent endovascular restoration of the aneurysm and was treated with broad-spectrum antibiotics. One and a half months later the fever relapsed and the chest CT scan revealed findings consistent with miliary tuberculosis and opacities of both upper lobes not present before, while the abdominal CT scan revealed an increase in the size of the para-aortic mass...
2017: Respiratory Medicine Case Reports
https://www.readbyqxmd.com/read/28120064/giant-basilar-artery-aneurysm-involving-the-origin-of-bilateral-posterior-cerebral-and-superior-cerebellar-arteries-neck-reconstruction-with-pconus-assisted-coiling
#8
Francesco Signorelli, Carmelo Lucio Sturiale, Giuseppe La Rocca, Alessio Albanese, Francesco D'Argento, Pierpaolo Mattogno, Alfredo Puca, Massimiliano Visocchi, Enrico Marchese, Alessandro Pedicelli
Giant aneurysms of the basilar artery are rare and are frequently associated with obstructive hydrocephalus and brainstem compression. Treatment still remains a challenge both for neurosurgeons and for interventional neuroradiologists. Cases reported in the literature are anecdotal and, overall, their outcomes are poor. We present the case of a patient with a giant aneurysm of the basilar artery tip, involving the origin of both the posterior cerebral and superior cerebellar arteries, who underwent coiling and ventriculoperitoneal shunting for associated obstructive hydrocephalus...
2017: Acta Neurochirurgica. Supplement
https://www.readbyqxmd.com/read/25146886/altered-expression-of-aurora-kinases-in-arabidopsis-results-in-aneu-and-polyploidization
#9
Dmitri Demidov, Inna Lermontova, Oda Weiss, Joerg Fuchs, Twan Rutten, Katrin Kumke, Timothy F Sharbel, Daniel Van Damme, Nico De Storme, Danny Geelen, Andreas Houben
Aurora is an evolutionary conserved protein kinase family involved in monitoring of chromosome segregation via phosphorylation of different substrates. In plants, however, the involvement of Aurora proteins in meiosis and in sensing microtubule attachment remains to be proven, although the downstream components leading to the targeting of spindle assembly checkpoint signals to anaphase-promoting complex have been described. To analyze the three members of Aurora family (AtAurora1, -2, and -3) of Arabidopsis we employed different combinations of T-DNA insertion mutants and/or RNAi transformants...
November 2014: Plant Journal: for Cell and Molecular Biology
https://www.readbyqxmd.com/read/24820304/-clinical-investigation-to-compare-acgh-and-fish-in-preimplantationgenetic-diagnosis-of-chromosome-translocation-carriers
#10
COMPARATIVE STUDY
Yanxin Xie, Yanwen Xu, Benyu Miao, Yanhong Zeng, Jing Wang, Canquan Zhou
OBJECTIVE: To investigate the clinical use of array comparative genomic hybridization (aCGH) with fluorescence in situ hybridization (FISH) in preimplantion genetic diagnosis (PGD) for reciprocal and Robertsonian translocation carriers. METHODS: From Jan. 2012 to Jun. 2013, a total of 220 PGD cycles from 151 reciprocal translocation and 62 Robertsonian translocation carrier couples, including 33 cycles for reciprocal translocation carriers and 22 cycles for Robertsonian translocation carriers performed using array CGH, and 119 cycles for reciprocal translocation carriers and 46 cycles for Robertsonian translocation carriers performed using FISH were retrospectively studied...
March 2014: Zhonghua Fu Chan Ke za Zhi
https://www.readbyqxmd.com/read/24183976/hz08-reverse-the-aneuploidy-induced-cisplatin-resistance-in-gastric-cancer-by-modulating-the-p53-pathway
#11
Xuzhen Tang, Gang Hu, Chunhua Xu, Kedong Ouyang, Weirong Fang, Wenlong Huang, Jingjing Zhang, Fu Li, Ke Wang, Xiaoran Qin, Yunman Li
We evaluated the influence of DNA aneuploidy on chemotherapy-resistance in human Gastric cancer cell MKN45; we also evaluated the reversal effects of HZ08 on these cells and then preliminary investigated the possible involved pathway. We made use of a pair of human Gastric cancer cell dip-MKN45 (diploid MKN45) and aneu-MKN45 (aneuploid MKN45). Growth inhibition in response to chemotherapeutic drugs was evaluated by CellTiter-Glo Luminescent Cell Viability assay and clone formation assay. Flow cytometry and immuno-assay were applied to evaluate apoptosis and the expression of relative signaling molecules...
November 15, 2013: European Journal of Pharmacology
https://www.readbyqxmd.com/read/23276026/-chimney-technique-stent-implantation-to-the-left-common-carotid-artery-in-patient-treated-with-thoracic-aortic-stentgraft
#12
Tomasz Jargiełło, Michał Sojka, Radosław Krupiński, Andrzej Wolski, Małgorzata Szczerbo-Trojanowska
Proximal fixation is often limiting for endovascular thoracic aortic aneu. rysm repair and the stentgraft may need to cover the origin of the arch branch vessels. Chimney technique have been proposed to preserve flow into over stented branches during or after stent graft implantation. The aim of this report is to share our initial experience of this technique.
2012: Przegla̧d Lekarski
https://www.readbyqxmd.com/read/22650078/-genesis-of-cells-of-apical-meristems-and-realization-of-gametophytic-apomixis-in-flowering-plants
#13
A S Kashin
Based on our own and literature data on peculiarities of caryotypical variability, we concluded that gametophytic apomixis is naturally accompanied with phenomena of poly-, aneu-, and mixoploidy and that apomicts have genome instability manifesting at the level of meristematic somatic cells. In this connection, a hypothesis is substantiated that realization of this mode of seed reproduction in flowering plants is caused by modification of systems of cell cycle control, following after acts of hybridogenesis and/or polyploidization...
March 2012: Ontogenez
https://www.readbyqxmd.com/read/21574427/-cytogenetic-peculiarities-of-cell-genesis-in-apical-meristems-under-gametophytic-apomixis-using-autonomous-apomicts-of-the-asteraceae-as-an-example
#14
A S Kashin, M I Tsvetova, Iu A Demochko
Cytogenetic peculiarities of cell genesis in apical meristems of apomicts has been analyzed using a series of the Asteraceae species as an example. The extent to which aneu- and mixoploids are spread among plants in the investigated populations of the Asteraceae species is so high (up to 30-60% of the studied plants and their offspring), that it seems reasonable to suppose that their rise is a natural phenomenon. It has been shown that in the aposporous facultative apomict Pilosella officinarum microgametophyte is a relatively stable element of the seed reproduction system from the point of view of caryotypical variation...
March 2011: T︠S︡itologii︠a︡ i Genetika
https://www.readbyqxmd.com/read/21472411/genetic-analysis-of-the-sugarcane-saccharum-spp-cultivar-lcp-85-384-i-linkage-mapping-using-aflp-ssr-and-trap-markers
#15
Suman Andru, Yong-Bao Pan, Songkran Thongthawee, David M Burner, Collins A Kimbeng
Sugarcane hybrids are complex aneu-polyploids (2n = 100-130) derived from inter-specific hybridization between ancestral polyploid species, namely S. officinarum L. and S. spontaneum L. Efforts to understand the sugarcane genome have recently been enhanced through the use of new molecular marker technologies. A framework genetic linkage map of Louisiana's popular cultivar LCP 85-384 was constructed using the selfed progeny and based on polymorphism derived from 64 AFLP, 19 SSR and 12 TRAP primer pairs. Of 1,111 polymorphic markers detected, 773 simplex (segregated in 3:1 ratio) and 182 duplex (segregate in 77:4 ratio) markers were used to construct the map using a LOD value of ≥ 4...
June 2011: TAG. Theoretical and Applied Genetics. Theoretische und Angewandte Genetik
https://www.readbyqxmd.com/read/20512558/apomixis-and-ploidy-barrier-suppress-pollen-mediated-gene-flow-in-field-grown-transgenic-turf-and-forage-grass-paspalum-notatum-fl%C3%A3-gg%C3%A3
#16
Sukhpreet Sandhu, Ann R Blount, Kenneth H Quesenberry, Fredy Altpeter
Bahiagrass (Paspalum notatum Flüggé) is the predominant forage grass in the southeastern US. The commercially important bahiagrass cultivar 'Argentine' is preferred for genetic transformation over sexual diploid cytotypes, since it produces uniform seed progeny through apomixis. Pseudogamous apomictic seed production in Argentine bahiagrass may contribute to transgene confinement. It is characterized by embryo development which is independent of fertilization of the egg cell, but requires fertilization with compatible pollen to produce the endosperm...
September 2010: TAG. Theoretical and Applied Genetics. Theoretische und Angewandte Genetik
https://www.readbyqxmd.com/read/20464968/-the-influence-of-ferromagnetic-screening-from-natural-electromagnetic-fields-on-the-hematological-and-toxicogenomic-indexes-in-animals
#17
S D Ivanov, V N Nikitina, V A Iamshanov, E G Kovan'ko, G G Liashko, A S Monakhov, V K Koshelevskiĭ
The aim of the study was to reveal during 45 days consequences of ferromagnetic screening (FS) on the hematological and toxicogenomic indexes in rats. An express-method of nucleiod DNA content in blood by help fluorescent indication was used for alive quantitative evaluation of the toxicogenomic effects. The FS for both gender rats during 48 hrs resulted in both decreased magnetic field by 4-10 microT1 and leucopenia by 14 day of experiment. The aneu-/polyploidy index in male leucocytes was increased by 48 hr of FS and lasted out to 12-28 days after the screen removal...
March 2010: Radiatsionnaia Biologiia, Radioecologiia
https://www.readbyqxmd.com/read/19701742/risk-assessment-of-transgenic-apomictic-tetraploid-bahiagrass-cytogenetics-breeding-behavior-and-performance-of-intra-specific-hybrids
#18
Sukhpreet Sandhu, Victoria A James, Kenneth H Quesenberry, Fredy Altpeter
Pollen-mediated gene transfer from stress tolerant or herbicide-resistant transgenic plants may cause environmental or agronomic problems. Apomictic seed production found in some bahiagrass cultivars may serve as a natural transgene containment system. Under greenhouse conditions, the average gene transfer frequency from an herbicide-resistant apomictic tetraploid to a population of sexual diploid bahiagrass genotypes or apomictic tetraploid bahiagrass was 0.16% when the transgenic pollen donor was placed at 0...
November 2009: TAG. Theoretical and Applied Genetics. Theoretische und Angewandte Genetik
https://www.readbyqxmd.com/read/19078333/ruptured-intrahepatic-aneurysm-as-the-initial-manifestation-of-polyarteritis-nodosa
#19
G R Komatireddy, D T Yangco, T S Loy, G D Beale
polyarteritis nodosa (PAN) is characterized by panarteritis involving all layers of the vessel wall of medium and small arteries and adjacent veins leading to thrombosis and aneurysmal dilatation. We present the case of a 21-year-old Caucasian man with an acute abdomen with a massive gastrointestinal (GI) hemorrhage caused by a large intrahepatic aneurysmal rupture needing surgery. This was the initial manifestation of underlying PAN, which had not been diagnosed before the event. This patient's postoperative course was complicated by continued hemorrhage prompting further diagnostic abdominal arteriography, which revealed multiple art-eurysms along the superior mesenteric artery...
December 1998: Journal of Clinical Rheumatology: Practical Reports on Rheumatic & Musculoskeletal Diseases
https://www.readbyqxmd.com/read/18425470/rapid-prenatal-aneuploidy-screening-by-fluorescence-in-situ-hybridization-fish
#20
Anja Weise, Thomas Liehr
The most common aneuploidies in prenatal diagnostics of the second trimenon are trisomies of chromosomes 13, 18, and 21 and gonosomal abnormalities. To detect these trisomies as quickly as possible after amniocentesis, besides using polymerase chain reaction, fluorescence in situ hybridization (FISH), applying corresponding centromeric or locus-specific probes, is the method of choice. Results of a rapid prenatal aneuploidy screening in uncultured amniocytes by using FISH are available within 24 hr or less...
2008: Methods in Molecular Biology
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