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https://www.readbyqxmd.com/read/28092847/repetitive-transcranial-magnetic-stimulation-for-the-treatment-of-post-stroke-depression-a-systematic-review-and-meta-analysis-of-randomized-controlled-clinical-trials
#1
REVIEW
XinYi Shen, MingYi Liu, Yu Cheng, Cui Jia, XinYue Pan, QingYun Gou, XinLian Liu, Hui Cao, LuShun Zhang
BACKGROUND: Every year, more than fifteen million people worldwide experience a stroke, nearly 30% of stroke survivors are likely to experience post-stroke depression (PSD). Repetitive transcranial magnetic stimulation (rTMS) is one of the emerging techniques which assist in targeting rehabilitation after stroke. Although deterioration of PSD greatly affects the recovery and quality of life of stroke sufferers, the effect of rTMS therapy has not been systematically studied. OBJECTIVE: A systematic review and meta-analysis was conducted to determine the effect of rTMS on PSD...
January 10, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28092843/therapeutic-effects-of-bach1-sirna-on-human-breast-adenocarcinoma-cell-line
#2
Mansoor Aletaha, Behzad Mansoori, Ali Mohammadi, Mehdi Fazeli, Behzad Baradaran
BACKGROUND: Despite the great improvements in clinical and therapeutic techniques in recent years, many advanced breast cancer patients still died of the postoperative recurrence and metastasis of disease. Bach1 plays a role in the development of the invasive phenotypes of cancer, cell division and apoptosis in tumor cells. The aim of this study was to investigate the effect of specific bach1 siRNAs, on the proliferation, migration, invasive, induction of apoptosis, cell cycle arrest and alter EMT related miRNA of MDA-MB-468 cells (breast cancer)...
January 13, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28092813/walking-mechanics-for-patellofemoral-pain-subjects-with-similar-self-reported-pain-levels-can-differ-based-upon-neuromuscular-activation
#3
Matthew K Seeley, S Jun Son, Hyunsoo Kim, J Ty Hopkins
Patellofemoral pain (PFP) is often studied on subjects who are classified using only self-reported data. Neuromuscular activation influences movement mechanics for PFP subjects, but is not likely to be self-reported. We compared lower-extremity mechanics, during a common movement (walking), between two subdivisions of a group of PFP subjects that were similar, based on common self-report tools, but different, based on a common objective measure of quadriceps activation. Our intent was to highlight the importance of objectively considering neuromuscular activation when researching PFP movement mechanics...
January 9, 2017: Gait & Posture
https://www.readbyqxmd.com/read/28092802/signal-and-binding-i-physico-chemical-response-to-macromolecule-ligand-interactions
#4
REVIEW
Wlodzimierz Bujalowski, Maria J Jezewska, Paul J Bujalowski
Obtaining a detailed knowledge about energetics of ligand-macromolecule interactions is a prerequisite for elucidation of the nature, behavior, and activities of the formed complexes. The most commonly used methods in characterizing molecular interactions are physico-chemical techniques based mainly on spectroscopic, calorimetric, hydrodynamic, etc., measurements. The major advantage of the physico-chemical methods is that they do not require large quantities of material and, if performed carefully, do not perturb examined reactions...
January 3, 2017: Biophysical Chemistry
https://www.readbyqxmd.com/read/28092801/the-association-between-personal-income-and-aging-a-population-based-13-year-longitudinal-study
#5
Tzu-Yu Lin, Chia-Yu Chen, Chueh-Yung Tsao, Kuang-Hung Hsu
INTRODUCTION: Population aging is set to increase the elder dependency ratio, causing a rapid increase in healthcare expenditures and financial burden on the government. This study aims to construct an aging score from age-related diseases and to perform longitudinal analyses to examine the association between personal income and aging. METHODS: A total of 86,838 subjects drawn from a community with 384,617 residents in northern Taiwan were examined. Personal income and aging-related diseases were measured from the National Health Insurance database during 1997-2010...
January 9, 2017: Archives of Gerontology and Geriatrics
https://www.readbyqxmd.com/read/28092766/effect-of-multi-walled-carbon-nanotubes-on-phytotoxicity-of-sediments-contaminated-by-phenanthrene-and-cadmium
#6
Biao Song, Guangming Zeng, Jilai Gong, Peng Zhang, Jiaqin Deng, Canhui Deng, Jin Yan, Piao Xu, Cui Lai, Chen Zhang, Min Cheng
To implement effective control and abatement programs for contaminants accumulating in sediments, strategies are needed for evaluating the quality of amended sediments. In this study, phytotoxicity of the sediments contaminated by cadmium and phenanthrene was evaluated after in situ remediation with multi-walled carbon nanotubes (MWCNTs) as adsorbents. Adsorption experiments and measurement of aqueous concentrations of the contaminants in overlying water were used to investigate the remediation effectiveness from physical and chemical aspects...
January 9, 2017: Chemosphere
https://www.readbyqxmd.com/read/28092762/a-novel-approach-for-exposure-assessment-in-air-pollution-epidemiological-studies-using-neuro-fuzzy-inference-systems-comparison-of-exposure-estimates-and-exposure-health-associations
#7
Victoria Blanes-Vidal, Manuella Lech Cantuaria, Esmaeil S Nadimi
Many epidemiological studies have used proximity to sources as air pollution exposure assessment method. However, proximity measures are not generally good surrogates because of their complex non-linear relationship with exposures. Neuro-fuzzy inference systems (NFIS) can be used to map complex non-linear systems, but its usefulness in exposure assessment has not been extensively explored. We present a novel approach for exposure assessment using NFIS, where the inputs of the model were easily-obtainable proximity measures, and the output was residential exposure to an air pollutant...
January 13, 2017: Environmental Research
https://www.readbyqxmd.com/read/28092739/an-emg-driven-biomechanical-model-of-the-canine-cervical-spine
#8
M Alizadeh, G G Knapik, J S Dufour, C Zindl, M J Allen, J Bertran, N Fitzpatrick, W S Marras
Due to the frequency of cervical spine injuries in canines, the purpose of this effort was to develop an EMG-driven dynamic model of the canine cervical spine to assess a biomechanical understanding that enables one to investigate the risk of neck disorders. A canine subject was recruited in this investigation in order to collect subject specific data. Reflective markers and a motion capture system were used for kinematic measurement; surface electrodes were used to record electromyography signals, and with the aid of force plate kinetics were recorded...
December 26, 2016: Journal of Electromyography and Kinesiology
https://www.readbyqxmd.com/read/28092700/association-between-thyroid-autoimmunity-and-helicobacter-pylori-infection
#9
Yun Mi Choi, Tae Yong Kim, Eui Young Kim, Eun Kyung Jang, Min Ji Jeon, Won Gu Kim, Young Kee Shong, Won Bae Kim
Background/Aims: There have been controversial reports linking Helicobacter pylori infection to autoimmune thyroid disease (AITD). However, data regarding the relationship are limited for Asian populations, which have an extremely high prevalence of H. pylori infection. We performed this study to investigate the association between H. pylori infection and AITD in Koreans. Methods: This study involved adults aged 30 to 70 years who had visited a health promotion center...
January 16, 2017: Korean Journal of Internal Medicine
https://www.readbyqxmd.com/read/28092680/utilizing-somatic-mutation-data-from-numerous-studies-for-cancer-research-proof-of-concept-and-applications
#10
D Amar, S Izraeli, R Shamir
Large cancer projects measure somatic mutations in thousands of samples, gradually assembling a catalog of recurring mutations in cancer. Many methods analyze these data jointly with auxiliary information with the aim of identifying subtype-specific results. Here, we show that somatic gene mutations alone can reliably and specifically predict cancer subtypes. Interpretation of the classifiers provides useful insights for several biomedical applications. We analyze the COSMIC database, which collects somatic mutations from The Cancer Genome Atlas (TCGA) as well as from many smaller scale studies...
January 16, 2017: Oncogene
https://www.readbyqxmd.com/read/28092654/promoter-polymorphism-of-toll-like-receptor-4-is-associated-with-a-decreased-risk-of-coronary-artery-disease-a-case-control-study-in-the-chinese-han-population
#11
Dandan Sun, Liping Sun, Qian Xu, Honghu Wang, Jun Yang, Yuan Yuan
BACKGROUND Coronary artery disease (CAD) is considered a chronic inflammatory disease of the blood vessels. Toll-like receptor 4 (TLR4) is a transmembrane receptor involved in inflammatory reactions. The aim of this study was to determine the association between polymorphisms in the promoter region and 3'-untranslated region (3'-UTR) of TLR4, and the associated CAD risk. MATERIAL AND METHODS This study enrolled 424 participants with CAD and 424 controls without CAD. The polymorphisms in the promoter region and 3'-UTR of TLR4 were identified from the HapMap database, including rs10116253, rs10983755, and rs11536889...
January 16, 2017: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/28092641/performance-characterization-of-a-novel-electronic-number-connection-test-to-detect-minimal-hepatic-encephalopathy-in-cirrhotic-patients
#12
Tilo Wuensch, Darius Ferenc Ruether, Caroline Zöllner, Tobias Mueller, Tobias Jung, Magnus Kaffarnik, Ursula Kassner, Eckart Schott, Stephan Kiefer, Johann Pratschke, Martin Stockmann, Maximilian Jara
BACKGROUND AND AIM: Hepatic encephalopathy (HE) is a frequent complication of cirrhosis, characterized by cognitive deficits that negatively impact patients' quality of life. The mild, minimal hepatic encephalopathy (mHE) can only be detected by psychometric tests and early mHE detection can prevent more severe complications or even survival times. Here, we aimed to investigate the feasibility and validity of the novel-developed electronic number connection test (eNCT), which is designed as a fast and easy-to-perform mHE patient self-test...
January 12, 2017: European Journal of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/28092636/an-analysis-of-intrinsic-variations-of-low-frequency-shear-wave-speed-in-a-stochastic-tissue-model-the-first-application-for-staging-liver-fibrosis
#13
Yu Wang, Min Wang, Jingfeng Jiang
Shear wave elastography is increasingly being used to non-invasively stage liver fibrosis by measuring shear wave speed (SWS). This study quantitatively investigates intrinsic variations among SWS measurements obtained from heterogeneous media such as fibrotic livers. More specifically, it aims to demonstrate that intrinsic variations in SWS measurements, in general, follow a non-Gaussian distribution and are related to the heterogeneous nature of the medium being measured. Using the principle of maximum entropy (ME), our primary objective is to derive a probability density function (PDF) of the SWS distribution in conjunction with a lossless stochastic tissue model...
February 7, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/28092624/changes-in-reticulorumen-content-temperature-and-ph-according-to-time-of-day-and-yearly-seasons
#14
R Antanaitis, V Žilaitis, V Juozaitienė, R Stoškus, M Televičius
The monitoring of rumen content temperature can be useful for the evaluation of cow health condition and heat. The aim of this research was to evaluate the influence of the circadian rhythm (time of day) and season on reticulorumen acidity (pH) and temperatures (RT) in lactating dairy cows. The research was performed on ten 2nd - lactation, clinically healthy Lithuanian Black and White fresh dairy cows (up to 1 day after calving). The cows were milked twice daily at 05:00 and 17:00. The cows were kept in a loose housing system, and were fed a feed ration throughout the year at the same time, balanced according to their physiological needs...
December 1, 2016: Polish Journal of Veterinary Sciences
https://www.readbyqxmd.com/read/28092607/proanp-as-a-screening-biomarker-for-hypertrophic-cardiomyopathy-in-maine-coon-cats
#15
M Parzeniecka-Jaworska, M Garncarz, W Kluciński
: The aim of this study was to determine if atrial natriuretic peptide can be used as an early screening tool for hypertrophic cardiomyopathy in Maine coon cats. ANIMALS: The study was performed in 43 Maine coon cats of both sexes, aged 11 to 92 months. Clinical and echocardiographic examinations were done and proANP serum concentrations were measured every three months over a period of one year (each cat had a total of five examinations). Cats were divided into 3 groups based on echocardiographic results: group 1 - healthy cats, group 2 - cats with unequivocal hypertrophic cardiomyopathy results, group 3 - cats with HCM...
December 1, 2016: Polish Journal of Veterinary Sciences
https://www.readbyqxmd.com/read/28092588/a-many-objective-evolutionary-algorithm-using-a-one-by-one-selection-strategy
#16
Yiping Liu, Dunwei Gong, Jing Sun, Yaochu Jin
Most existing multiobjective evolutionary algorithms experience difficulties in solving many-objective optimization problems due to their incapability to balance convergence and diversity in the high-dimensional objective space. In this paper, we propose a novel many-objective evolutionary algorithm using a one-by-one selection strategy. The main idea is that in the environmental selection, offspring individuals are selected one by one based on a computationally efficient convergence indicator to increase the selection pressure toward the Pareto optimal front...
January 9, 2017: IEEE Transactions on Cybernetics
https://www.readbyqxmd.com/read/28092562/line-graph-or-scatter-plot-automatic-selection-of-methods-for-visualizing-trends-in-time-series
#17
Yunhai Wang, Fubo Han, Lifeng Zhu, Oliver Deussen, Baoquan Chen
Line graphs are usually considered to be the best choice for visualizing time series data, whereas sometimes also scatter plots are used for showing main trends. So far there are no guidelines that indicate which of these visualization methods better display trends in time series for a given canvas. Assuming that the main information in a time series is its overall trend, we propose an algorithm that automatically picks the visualization method that reveals this trend best. This is achieved by measuring the visual consistency between the trend curve represented by a LOESS fit and the trend described by a scatter plot or a line graph...
January 16, 2017: IEEE Transactions on Visualization and Computer Graphics
https://www.readbyqxmd.com/read/28092556/study-of-saliency-in-objective-video-quality-assessment
#18
Wei Zhang, Hantao Liu
Reliably predicting video quality as perceived by humans remains challenging and is of high practical relevance. A significant research trend is to investigate visual saliency and its implications for video quality assessment. Fundamental problems regarding how to acquire reliable eye-tracking data for the purpose of video quality research and how saliency should be incorporated in objective video quality metrics (VQMs) are largely unsolved. In this paper, we propose a refined methodology for reliably collecting eye-tracking data, which essentially eliminates bias induced by each subject having to view multiple variations of the same scene in a conventional experiment...
January 10, 2017: IEEE Transactions on Image Processing: a Publication of the IEEE Signal Processing Society
https://www.readbyqxmd.com/read/28092554/graph-laplacian-regularization-for-image-denoising-analysis-in-the-continuous-domain
#19
Jiahao Pang, Gene Cheung
Inverse imaging problems are inherently underdetermined, and hence it is important to employ appropriate image priors for regularization. One recent popular prior- the graph Laplacian regularizer-assumes that the target pixel patch is smooth with respect to an appropriately chosen graph. However, the mechanisms and implications of imposing the graph Laplacian regularizer on the original inverse problem are not well understood. To address this problem, in this paper we interpret neighborhood graphs of pixel patches as discrete counterparts of Riemannian manifolds and perform analysis in the continuous domain, providing insights into several fundamental aspects of graph Laplacian regularization for image denoising...
January 11, 2017: IEEE Transactions on Image Processing: a Publication of the IEEE Signal Processing Society
https://www.readbyqxmd.com/read/28092548/linear-spectral-clustering-superpixel
#20
Jiansheng Chen, Zhengqin Li, Bo Huang
In this paper, we present a superpixel segmentation algorithm called linear spectral clustering (LSC), which is capable of producing superpixels with both high boundary adherence and visual compactness for natural images with low computational costs. In LSC, a normalized cuts based formulation of image segmentation is adopted using a distance metric that measures both the color similarity and the space proximity between image pixels. However, rather than directly using the traditional eigen-based algorithm, we approximate the similarity metric through a deliberately designed kernel function such that pixel values can be explicitly mapped to a high-dimensional feature space...
January 11, 2017: IEEE Transactions on Image Processing: a Publication of the IEEE Signal Processing Society
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