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Newborn infant

C Casper, I Sarapuk, H Pavlyshyn
INTRODUCTION: Skin-to-skin contact (SSC) is a cornerstone of neurodevelopment and family-oriented care for preterm infants. The purpose of the present study was to investigate the effectiveness of skin-to-skin contact in preterm babies depending on regularity, duration, and the period of the first contact. MATERIALS AND METHODS: This retrospective study involved 26 premature infants with gestational age 24/0-28/6 weeks who were treated in the neonatal intensive care unit and neonatal department...
October 16, 2018: Archives de Pédiatrie: Organe Officiel de la Sociéte Française de Pédiatrie
Jisun Yun, Inha Lee, Young Bin Won, Jae Hoon Lee, Seok Kyo Seo, SiHyun Cho, Young Sik Choi, Byung Seok Lee, Bo Hyon Yun
This retrospective study investigated and compared the incidence of congenital foetal anomalies after letrozole versus clomiphene citrate (CC) administration for infertility treatment. Data from 142 newborns were included: letrozole group, n = 83; CC group, n = 61. Congenital anomalies were found in 7.2% (6/83) patients in the letrozole group and 18.0% (11/61) patients in the CC group, with no significant between-group difference (p = .066). Major congenital anomaly rate was 2.4% (2/83) in the letrozole group and 3...
October 16, 2018: Reproductive Toxicology
(no author information available yet)
No abstract text is available yet for this article.
November 2018: MCN. the American Journal of Maternal Child Nursing
Christine OʼMalley, Sudhir Sriram, Melissa White, Carol Polinski, Carolyn Seng, Michael D Schreiber
BACKGROUND: Low birth-weight infants' survival continues to improve and there is increased need to provide secure vascular access. This study examines safety of larger peripherally inserted central catheters (PICCs) that offer greater utility. PURPOSE: To determine feasibility of 2.6-French (Fr) double-lumen PICCs in newborns and compare noninfectious complications such as thrombus formation, catheter breakage, infiltration, and accidental dislodgment and central line-associated bloodstream infection (CLABSI) rate with that of newborn infants treated with 1...
October 18, 2018: Advances in Neonatal Care: Official Journal of the National Association of Neonatal Nurses
Mônica Hiromi Sato, Mavilde da Luz Gonçalves Pedreira, Ariane Ferreira Machado Avelar, Miriam Harumi Tsunemi, Kelly Cristina Sbampato Calado Orsi, Marcia Lurdes de Cacia Pradella-Hallinan, Marta José Avena, Eliana Moreira Pinheiro
The purpose of this study was to compare the effect of ear protectors on the sleep of preterm newborns during the "quiet" times in intermediate care nursery. This was a clinical, randomized, controlled crossover study conducted in two neonatal units in São Paulo, Brazil. The sample consisted of preterm infants who met the inclusion and exclusion criteria for the study. Polysomnography and unstructured observation were used for data collection. Twenty-four preterm infants with a mean gestational age of 33...
October 19, 2018: Clinical Nursing Research
Natasha Aluloska, Snezana Janchevska, Velibor Tasic
BACKGROUND: Neonatal renal vein thrombosis is the most common vascular condition in the newborn kidney, which could lead to serious complication in infants. CASE REPORT: We report a case of the unilateral renal vein and inferior vena cava thrombosis, presented with gross hematuria and thrombocytopenia in a neonate. The neonate was a macrosomic male born to a mother with hyperglycemia in pregnancy. The baby was born with perinatal asphyxia and early neonatal infection and massive hematuria...
September 25, 2018: Open Access Macedonian Journal of Medical Sciences
Lei-Qing Yang, Min Chen, Jun-Long Zhang, Da-Long Ren, Bing Hu
Hypoxia in newborns tends to result in developmental deficiencies in the white matter of the brain. As previous studies of the effects of hypoxia on neuronal development in rodents and human infants have been unable to use in vivo imaging, insight into the dynamic development of oligodendrocytes (OLs) in the central nervous system under hypoxia is limited. Here, we developed a visual model to study OL development using sublethal postnatal hypoxia in zebrafish larvae. We observed that hypoxia significantly suppressed OL progenitor cell migration toward the dorsum using in vivo imaging...
2018: Frontiers in Cellular Neuroscience
Mark B Tracy, Robert Halliday, Sally K Tracy, Murray K Hinder
AIM: A controlled bench test was undertaken to determine the performance variability among a range of neonatal self-inflating bags (SIB) compliant with current International Standards Organisation (ISO). INTRODUCTION: Use of SIB to provide positive pressure ventilation during newborn resuscitation is a common emergency procedure. The United Nations programmes advocate increasing availability of SIB in low-income and middle-income nations and recommend devices compliant with ISO...
October 18, 2018: Archives of Disease in Childhood. Fetal and Neonatal Edition
Kiersten Israel-Ballard
No abstract text is available yet for this article.
October 2018: Breastfeeding Medicine: the Official Journal of the Academy of Breastfeeding Medicine
Ilona C Narayen, Arjan B Te Pas, Nico A Blom, M Elske van den Akker-van Marle
Pulse oximetry (PO) screening is used to screen newborns for critical congenital heart defects (CCHD). Analyses performed in hospital settings suggest that PO screening is cost-effective. We assessed the costs and cost-effectiveness of PO screening in the Dutch perinatal care setting, with home births and early postnatal discharge, compared to a situation without PO screening. Data from a prospective accuracy study with 23,959 infants in the Netherlands were combined with a time and motion study and supplemented data...
October 17, 2018: European Journal of Pediatrics
Isabel de Roever, Gemma Bale, Subhabrata Mitra, Judith Meek, Nicola J Robertson, Ilias Tachtsidis
It has been 20 years since functional near-infrared spectroscopy (fNIRS) was first used to investigate the evoked hemodynamic response to a stimulus in newborns. The hemodynamic response to functional activation is well-established in adults, with an observed increase in concentration change of oxygenated hemoglobin (Δ[HbO2 ]) and decrease in deoxygenated hemoglobin (Δ[HHb]). However, functional studies in newborns have revealed a mixed response, particularly with Δ[HHb] where an inconsistent change in direction is observed...
2018: Frontiers in Human Neuroscience
Maria Bianchi, Patrizia Papacci, Caterina Giovanna Valentini, Ombretta Barbagallo, Giovanni Vento, Luciana Teofili
The prevention and treatment of anaemia in newborn patients made tremendous progress in the last decades. However, red-blood-cell (RBC) transfusions remain unavoidable in many neonates candidate to surgery and especially in preterm infants. In particular, anaemia occurring in neonates born at extremely low gestational age is actually severe and frequently requires transfusions. Several approaches have been explored to prevent or even to reduce the threshold and the frequency of RBC transfusions. Among these, umbilical cord blood (UCB) collection and processing to obtain RBC components for autologous or allogeneic transfusion have been extensively investigated...
October 16, 2018: Vox Sanguinis
Ye Ji Shim, Byung Yoon Choi, Kyo Hoon Park, Hyunju Lee, Young Mi Jung, Yu Mi Kim
Objective: We aimed to determine whether elevated levels of various inflammatory and immune proteins in umbilical cord blood are associated with an increased risk of newborn hearing screening (NHS) test failure in preterm neonates. Methods: This retrospective cohort study included 127 premature singleton infants who were born at ≤33.6 weeks. Umbilical cord plasma at birth was assayed for interleukin (IL)-6, complement C3a and C5a, matrix metalloproteinase (MMP)-9, macrophage colony-stimulating factor (M-CSF), and endostatin levels using ELISA kits...
2018: Mediators of Inflammation
Behzad Yeganeh, Joyce Lee, Claudia Bilodeau, Irene Lok, Leonardo Ermini, Cameron Ackerley, Isabella Caniggia, Jeroen Tibboel, Andre Kroon, Martin Post
RATIONALE: Premature infants subjected to mechanical ventilation (MV) are prone to lung injury that may result in bronchopulmonary dysplasia. Mechanical ventilation causes epithelial cell death and halts alveolar development. The exact mechanism of MV-induced epithelial cell death is unknown. OBJECTIVE: To determine the contribution of autophagy to MV-induced epithelial cell death in newborn rat lungs. METHODS: Newborn rat lungs and fetal rat lung epithelial (FLRE) cells were exposed to MV and cyclic stretch, respectively, and were then analyzed by immunoblotting and mass spectrometry for autophagy, apoptosis and bioactive sphingolipids...
October 16, 2018: American Journal of Respiratory and Critical Care Medicine
Faruk Uguz, Goksen Yuksel, Ozge Sahmelikoglu Onur, Cagatay Karsidag, Kazim Gezginc, Nazile Arpaci
OBJECTIVE: The objective of the present study was to compare neonatal outcomes including gestational age, birth weight and hospitalization of newborns of pregnant women with treated with antidepressants and untreated panic disorder. METHODS: The study sample included 146 pregnant women (44 patients with panic disorder treated with antidepressants, 52 patients with untreated panic disorder, and 50 healthy controls). Panic disorder was diagnosed by means of the Structured Clinical Interview for the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition...
October 9, 2018: Comprehensive Psychiatry
(no author information available yet)
OBJECTIVES: to investigate whether specific nucleoside reverse transcriptase inhibitor (NRTI) backbones are associated with risk of adverse pregnancy outcomes among pregnant women starting antiretroviral therapy (ART) DESIGN:: Seven observational studies across eight European countries of pregnancies in HIV-positive women METHODS:: Individual-level data were pooled on singleton pregnancies conceived off-ART in which a single combination ART regimen was initiated ≥2 weeks before delivery, and ending in a live birth in 2008-2014...
October 15, 2018: AIDS
Tanja A J Houweling, David van Klaveren, Sushmita Das, Kishwar Azad, Prasanta Tripathy, Dharma Manandhar, Melissa Neuman, Erik de Jonge, Jasper V Been, Ewout Steyerberg, Anthony Costello
Background: In poor settings, where many births and neonatal deaths occur at home, prediction models of neonatal mortality in the general population can aid public-health policy-making. No such models are available in the international literature. We developed and validated a prediction model for neonatal mortality in the general population in India, Nepal and Bangladesh. Methods: Using data (49 632 live births, 1742 neonatal deaths) from rural and urban surveillance sites in South Asia, we developed regression models to predict the risk of neonatal death with characteristics known at (i) the start of pregnancy, (ii) start of delivery and (iii) 5 minutes post partum...
October 15, 2018: International Journal of Epidemiology
Alper Akın, Meki Bilici, Fikri Demir, Murat Muhtar Yılmazer, Mehmet Şah İpek, Hülya Kara
Akın A, Bilici M, Demir F, Yılmazer MM, İpek MŞ, Kara H. Percutaneous retrieval of umbilical vein catheter fragment in an infant two months after embolization. Turk J Pediatr 2018; 60: 191-193. Umbilical vein catheterization is frequently preferred and a safe route of venous access especially in newborns. However, some cases with breaking and embolization of those catheters have been rarely reported. Herein we present a two-and-a-half-month-old infant being catheterized within first postnatal week and diagnosed to have embolization of the catheter fragment to conjunction of hepatic vein and right atrium...
2018: Turkish Journal of Pediatrics
Samantha C Butler, Anjali Sadhwani, Christian Stopp, Jayne Singer, David Wypij, Carolyn Dunbar-Masterson, Janice Ware, Jane W Newburger
OBJECTIVE: Mortality rates for children with congenital heart disease (CHD) have significantly declined, resulting in a growing population with associated neurodevelopmental disabilities. American Heart Association guidelines recommend systematic developmental screening for children with CHD. The present study describes results of inpatient newborn neurodevelopmental assessment of infants after open heart surgery. OUTCOME MEASURES: We evaluated the neurodevelopment of a convenience sample of high-risk infants following cardiac surgery but before hospital discharge using an adaptation of the Newborn Behavioral Observation...
October 15, 2018: Congenital Heart Disease
Elizabeth P Zorn, Lei Zhang, Kristin Sandness, Neely Miller, Tracy Riggins, Michael K Georgieff, Katie M Pfister
OBJECTIVE: Survivors of neonatal encephalopathy (NE) are at risk for impaired cognition. The objective of this study was to assess speed of processing (SOP) and memory in infants with moderate NE. STUDY DESIGN: Sample consisted of 17 infants with NE and 23 healthy controls. Visual-evoked potentials (VEP) were assessed at 8 months to assess SOP. Memory was assessed at 12 months using elicited imitation (EI). Memory and SOP had previously been assessed in this cohort in the newborn period...
October 15, 2018: Journal of Perinatology: Official Journal of the California Perinatal Association
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