Hasni Kannangara, Liam Cullen, Sari Miyashita, Funda Korkmaz, Anne Macdonald, Anisa Gumerova, Ronit Witztum, Ofer Moldavski, Steven Sims, Jocoll Burgess, Tal Frolinger, Rauf Latif, Yelena Ginzburg, Daria Lizneva, Ki Goosens, Terry F Davies, Tony Yuen, Mone Zaidi, Vitaly Ryu
Seasonal changes in food intake and adiposity in many animal species are triggered by changes in the photoperiod. These latter changes are faithfully transduced into a biochemical signal by melatonin secreted by the pineal gland. Seasonal variations, encoded by melatonin, are integrated by third ventricular tanycytes of the mediobasal hypothalamus through the detection of the thyroid-stimulating hormone (TSH) released from the pars tuberalis. The mediobasal hypothalamus is a critical brain region that maintains energy homeostasis by acting as an interface between the neural networks of the central nervous system and the periphery to control metabolic functions, including ingestive behavior, energy homeostasis, and reproduction...
May 18, 2023: Annals of the New York Academy of Sciences