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https://www.readbyqxmd.com/read/29787490/clinical-performance-of-a-new-bitangential-mini-scleral-lens
#1
Henny M Otten, Bart J J J van der Linden, Esther-Simone Visser
SIGNIFICANCE: New bitangential mini-scleral lens designs provide a highly precise fit, follow the scleral shape, are comfortable to wear, and can correct residual astigmatism. This new scleral lens design complements the arsenal of medical contact lenses available to eye care practitioners. PURPOSE: The aim of this study was to evaluate the subjective and objective performance of a new mini-scleral lens design with a bitangential periphery. METHODS: In this observational study, data were collected for up to 15 months (median, 84 days; interquartile range, 76 days) from the left eyes of 133 patients fitted with this newly designed lens...
May 21, 2018: Optometry and Vision Science: Official Publication of the American Academy of Optometry
https://www.readbyqxmd.com/read/29785996/phacoemulsification-with-single-pass-four-throw-pupilloplasty-and-pre-descemet-s-endothelial-keratoplasty-for-management-of-cosmetic-iris-implant-complication
#2
Priya Narang, Keiki Mehta, Amar Agarwal
Placement of an anterior chamber iris implant for cosmetic reasons has been associated with development of various complications. Even after the implant has been explanted from the eye, it leaves a trail of after effects that necessitate surgical management. We describe a technique that comprises of performing phacoemulsification with single-pass four-throw pupilloplasty and a pre-Descemet's endothelial keratoplasty procedure for this eye with cosmetic iris implant complication.
June 2018: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/29785984/residency-evaluation-and-adherence-design-study-iii-ophthalmology-residency-training-in-india-then-and-now-improving-with-time
#3
Partha Biswas, Parikshit Madhav Gogate, Quresh Badr Maskati, Sundaram Natarajan, Lalit Verma, Payal K Bansal
Purpose: To gauge the differences in ophthalmology residency training, academic, clinical and surgical, in the last three decades of the 20th century and the first decade of the 21st century. Methods: A survey was conducted by the Academic and Research Committee of the All India Ophthalmological Society, in 2014-2016, using a prevalidated questionnaire, which was circulated to ophthalmologists to gauge the practicality of the teaching protocols of clinical and surgical skills during postgraduate residency program...
June 2018: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/29785085/-wet-transepithelial-phototherapeutic-keratectomy-in-the-management-of-persistent-epithelial-defects-in-the-graft
#4
Sergei V Churashov, Elena V Kudryashova, Alexei N Kulikov, Ernest V Boiko, Valerii F Chernysh, Dmitrii S Maltsev
Purpose: This study aimed to evaluate the efficacy of "wet" transepithelial phototherapeutic keratectomy (TE-PTK) for treating persistent epithelial defects (PEDs) in the corneal graft following penetrating keratoplasty (PKP). Methods: This study describes a noncomparative, prospective interventional case series. Patients with post-PKP graft epithelial defects lasting >3 months despite previous treatments with extensive wear soft contact lenses, amniotic membrane transplantation, and tarsorrhaphy were treated with wet TE-PTK...
2018: Clinical Ophthalmology
https://www.readbyqxmd.com/read/29784165/association-between-positive-corneal-rim-cultures-and-microbiology-screening-protocols-in-ontario
#5
Rahul A Sharma, John S Y Park, Yao Wang, Tinghua Zhang, Linda Sharpen, William Dixon, Rookaya Mather
OBJECTIVE: (i) To assess the rate of positive microbiological cultures of corneas prepared by the Eye Bank of Canada (Ontario Division) between January 1, 2012, and December 31, 2013; (ii) to review the microbiology protocols at the 5 major transplant centres in Ontario; and (iii) to assess the incidence of endophthalmitis during the study period. DESIGN: Retrospective chart review. PARTICIPANTS: A total of 4186 consecutive cultured corneal tissues prepared by the Eye Bank from January 1, 2012, to December 31, 2013...
June 2018: Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie
https://www.readbyqxmd.com/read/29781930/peripheral-corneal-hydrops-secondary-to-pellucid-marginal-degeneration-managed-with-a-manually-dissected-semicircular-endothelial-keratoplasty-lenticule
#6
Andrew M J Turnbull, Abdo Karim Tourkmani, Ramez Barbara, Parwez N Hossain, David F Anderson, Aris Konstantopoulos
No abstract text is available yet for this article.
May 16, 2018: Cornea
https://www.readbyqxmd.com/read/29781929/femtosecond-laser-assisted-graft-preparation-for-descemet-membrane-endothelial-keratoplasty
#7
Hamish D McKee, Vishal Jhanji
PURPOSE: To describe a technique of using a femtosecond laser to assist with graft preparation for Descemet membrane endothelial keratoplasty (DMEK). METHODS: A femtosecond laser was used to assist in graft preparation for 3 DMEK procedures. The donor cornea is mounted on a proprietary artificial anterior chamber. A partial thickness deep circular cut is made with the femtosecond laser through the endothelium, Descemet membrane, and posterior stroma. Graft preparation is then completed without the use of a corneal trephine...
May 16, 2018: Cornea
https://www.readbyqxmd.com/read/29781928/interface-fungal-keratitis-after-descemet-stripping-automated-endothelial-keratoplasty-a-review-of-the-literature-with-a-focus-on-outcomes
#8
Elizabeth McElnea, Billy Power, Conor Murphy
PURPOSE: To examine the management and associated outcomes of reported cases of interface fungal infection after Descemet stripping automated endothelial keratoplasty (EK). METHODS: A literature review identified reports of interface fungal infection after Descemet stripping automated EK. Data retrieved from the same included patient demographics, surgical procedure undertaken, donor rim culture result, clinical course, and outcome. A review of the relevant literature was also conducted...
May 16, 2018: Cornea
https://www.readbyqxmd.com/read/29781926/repeatability-and-intersession-reproducibility-of-pentacam-corneal-thickness-maps-in-fuchs-dystrophy-and-endothelial-keratoplasty
#9
David Mingo-Botín, Francisco Arnalich-Montiel, Ana Couceiro de Juan, Sara Ortiz-Toquero
PURPOSE: To assess intrasession repeatability and intersession reproducibility of Pentacam corneal thickness maps in patients with Fuchs endothelial corneal dystrophy (FECD) before and after endothelial transplantation. METHODS: In this observational diagnostic evaluation, 20 healthy subjects along with 81 consecutive patients were examined. Patients were classified into 4 groups: FECD without corneal edema, FECD with corneal edema, Descemet stripping automated endothelial keratoplasty, and Descemet membrane endothelial keratoplasty...
May 16, 2018: Cornea
https://www.readbyqxmd.com/read/29773458/outcomes-of-conventional-phacoemulsification-versus-femtosecond-laser-assisted-cataract-surgery-in-eyes-with-fuchs-endothelial-corneal-dystrophy
#10
Dagny C Zhu, Parth Shah, William J Feuer, Wei Shi, Ellen H Koo
PURPOSE: To compare the outcomes in eyes with Fuchs endothelial corneal dystrophy after standard phacoemulsification with those of femtosecond laser-assisted cataract surgery. SETTING: Bascom Palmer Eye Institute, Miami, Florida, USA. DESIGN: Retrospective case series. METHODS: Charts from patients diagnosed with Fuchs endothelial corneal dystrophy who had phacoemulsification cataract surgery at Bascom Palmer Eye Institute between January 1, 2014, and January 1, 2017, were reviewed...
May 15, 2018: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/29773311/-corneal-endothelial-cell-therapy-a-review
#11
REVIEW
V Kocaba, O Damour, C Auxenfans, C Burillon
In France, endothelial dysfunction represents approximately one half of the indications for corneal transplants performed each year. However, the use of endothelial keratoplasty is limited by the technical difficulty of the procedure, a shortage of available grafts, and the potential for graft failure or rejection. These limitations are driving researchers to develop new, less invasive, and more effective therapies. Corneal endothelial cell therapy is being explored as a potential therapeutic measure, to avoid the uncertainty associated with grafting...
May 14, 2018: Journal Français D'ophtalmologie
https://www.readbyqxmd.com/read/29766356/endothelial-cell-loss-and-graft-survival-after-penetrating-keratoplasty-for-laser-iridotomy-induced-bullous-keratopathy
#12
Naoki Okumura, Ayaka Kusakabe, Noriko Koizumi, Koichi Wakimasu, Kanae Kayukawa, Masami Kondo, Kazuhiko Mori, Chie Sotozono, Shigeru Kinoshita
PURPOSE: To assess corneal endothelial cell loss after penetrating keratoplasty (PK) treatment for laser iridotomy (LI)-induced bullous keratopathy (BK). METHODS: A retrospective study conducted on consecutive patients who underwent PK between March 2000 and December 2011. Patients who had undergone more than 24 months of follow-up were included. Patients who underwent PK were subcategorized into two groups based on their diagnosis of BK prior to PK; PK was performed to treat either LI-BK or non LI-BK...
May 15, 2018: Japanese Journal of Ophthalmology
https://www.readbyqxmd.com/read/29763611/risk-of-glaucoma-surgery-after-corneal-transplant-surgery-in-medicare-patients
#13
Chengjie Zheng, Fei Yu, Victoria L Tseng, Flora Lum, Anne L Coleman
PURPOSE: Glaucoma is a well-documented complication of corneal transplants, contributing significantly to ultimate visual loss. Reported incidence of glaucoma following corneal transplants is highly variable, and definitions of post-transplant glaucoma are inconsistent. Here we use glaucoma surgery as a more rigid and specific endpoint to compare rates following different corneal transplant surgeries. DESIGN: Retrospective cohort study METHODS: A 5% random sample of Medicare beneficiaries from 2010-2013 was obtained and patients were identified with Current Procedural Terminology (CPT) codes for penetrating keratoplasty (PK), endothelial keratoplasty (EK), anterior lamellar keratoplasty (ALK), and keratoprosthesis (KPro)...
May 12, 2018: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/29758184/therapeutic-penetrating-keratoplasty-button-cultures-in-the-mycotic-ulcer-treatment-trial-ii-a-randomized-trial-comparing-oral-voriconazole-vs-placebo
#14
Julie Cho, N Venkatesh Prajna, Prajna Lalitha, Revathi Rajaraman, Tiruvengada Krishnan, Yijie Brittany Lin, Kathryn J Ray, Thomas M Lietman, Jennifer Rose-Nussbaumer
OBJECTIVE: To compare oral voriconazole versus placebo in addition to topical antifungals in the treatment of filamentous fungal keratitis. DESIGN: Non-prespecified, secondary case-control analysis from a multicenter, double-masked, randomized placebo-controlled clinical trial STUDY PARTICIPANTS: Patients with smear-positive filamentous fungal ulcers and visual acuity of 20/400 or worse who eventuated to therapeutic penetrating keratoplasty (TPK). INTERVENTION: Study participants were randomized to oral voriconazole versus oral placebo; all received topical antifungal drops...
May 11, 2018: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/29757853/multiplex-polymerase-chain-reaction-assay-for-screening-of-mycotoxin-genes-from-ocular-isolates-of-fusarium-species
#15
Orapin Anutarapongpan, Jorge Maestre-Mesa, Eduardo C Alfonso, Terrence P OʼBrien, Darlene Miller
PURPOSE: To identify mycotoxin genes among clinical ocular isolates of Fusarium species and to correlate these with clinical outcomes of Fusarium keratitis. METHODS: Fifty-four clinical isolates of Fusarium were retrieved from the Bascom Palmer Eye Institute Ocular Microbiology Laboratory data bank. Multiplex polymerase chain reactions were run to confirm the identification of Fusarium species [internal transcribed spacer sequence, translation elongation factor 1-α (TEF) and β-tubulin] and to detect the presence of genes encoding production of fumonisin B mycotoxins (FUM1 and FUM8) and trichothecene mycotoxins (deoxynivalenol and nivalenol)...
May 1, 2018: Cornea
https://www.readbyqxmd.com/read/29756410/the-feasibility-and-efficacy-of-preparing-porcine-descemet-s-membrane-endothelial-keratoplasty-dmek-grafts-by-two-techniques-an-ex-vivo-investigation-for-future-xeno-dmek
#16
Yang Liu, Jing Zhang, Yingnan Zhang, Mingyang Yin, Sen Miao, Qingfeng Liang, Zhiqiang Pan
BACKGROUND: Descemet's membrane endothelial keratoplasty (DMEK) might be a promising technique for future xeno-corneal transplantation due to its ultrathin graft, extremely low rejection occurrence, suture-free graft fixation, and minimal immunosuppressive regime usage. The aim of this study is to explore the feasibility and efficacy of preparing porcine DMEK grafts by 2 techniques and investigate the graft ultrastructure. METHODS: Two mainstream techniques, mechanical stripping technique and liquid bubble technique, were modified to prepare the porcine DMEK grafts...
May 13, 2018: Xenotransplantation
https://www.readbyqxmd.com/read/29755822/descemet-membrane-endothelial-keratoplasty-with-irregular-edged-graft-a-salvage-method-for-large-radial-graft-tears
#17
Mehmet Cüneyt Özmen, Nilay Dilekmen, Erdem Yüksel, Bahri Aydın, Fikret Akata
Large radial tears of donor Descemet membrane (DM) during the preparation of Descemet membrane endothelial keratoplasty (DMEK) grafts can make the trephination stage impossible because of small graft diameter. This results in irregular-edged grafts. In this study, we report two pseudophakic bullous keratopathy patients who underwent DMEK surgery with irregular-edged Descemet membrane (DM) grafts. Main outcome measures were preoperative and postoperative 1-, 3-, and 6-month best corrected visual acuity (BCVA), endothelial cell density (ECD) and central corneal thickness (CCT)...
April 2018: Turkish Journal of Ophthalmology
https://www.readbyqxmd.com/read/29746329/descemet-membrane-endothelial-keratoplasty-after-penetrating-keratoplasty-features-for-success
#18
Adi Einan-Lifshitz, Avner Belkin, Nir Sorkin, Zale Mednick, Tanguy Boutin, Ishrat Gill, Mohammad Karimi, Clara C Chan, David S Rootman
PURPOSE: To evaluate Descemet membrane endothelial keratoplasty (DMEK) in the setting of failed penetrating keratoplasty (PKP) and to identify factors associated with DMEK success and failure after PKP. METHODS: A retrospective chart review of patients who underwent DMEK for failed PKP at Toronto Western Hospital, Canada, between 2014 and 2017 was performed. Demographic characteristics, number of previous transplants, intraoperative and postoperative complications, best spectacle-corrected visual acuity (BSCVA), and endothelial cell density were analyzed...
May 8, 2018: Cornea
https://www.readbyqxmd.com/read/29746327/pediatric-corneal-transplants-review-of-current-practice-patterns
#19
Angela Y Zhu, Maria Carolina Marquezan, Courtney L Kraus, Christina R Prescott
PURPOSE: To facilitate development of standardized guidelines for management of pediatric patients undergoing keratoplasty, particularly the youngest cohort, through a comprehensive survey assessing recent trends in practice patterns of corneal specialists and pediatric ophthalmologists. METHODS: A cross-sectional, observational study of current practices pertaining to pediatric keratoplasty was performed by designing a 20-question survey focused on preoperative indications, surgical techniques, and postoperative management...
May 8, 2018: Cornea
https://www.readbyqxmd.com/read/29737973/in-vivo-endothelial-cell-density-decline-in-the-early-postoperative-phase-after-descemet-membrane-endothelial-keratoplasty
#20
Alina Miron, Marieke Bruinsma, Lisanne Ham, Sontje-Chiao Schaal, Lamis Baydoun, Isabel Dapena, Silke Oellerich, Gerrit R J Melles
PURPOSE: To evaluate endothelial cell density (ECD) in the first 6 months after Descemet membrane endothelial keratoplasty (DMEK) by eliminating method error as a confounding variable. METHODS: From 24 DMEK eyes operated for Fuchs endothelial corneal dystrophy, from which specular microscopy images could be taken at 1 day and 6 months postoperatively, ECD values were compared between these 2 time points. RESULTS: Using the 1-day ECD measurement as baseline, mean ECD decreased from 1913 (±326) cells/mm to 1524 (±393) cells/mm at 6 months, a decline of -18 (±19)%...
June 2018: Cornea
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