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https://www.readbyqxmd.com/read/27919334/ionizing-radiation-induced-cataracts-recent-biological-and-mechanistic-developments-and-perspectives-for-future-research
#1
Elizabeth A Ainsbury, Stephen Barnard, Scott Bright, Claudia Dalke, Miguel Jarrin, Sarah Kunze, Rick Tanner, Joseph R Dynlacht, Roy A Quinlan, Jochen Graw, Munira Kadhim, Nobuyuki Hamada
The lens of the eye has long been considered as a radiosensitive tissue, but recent research has suggested that the radiosensitivity is even greater than previously thought. The 2012 recommendation of the International Commission on Radiological Protection (ICRP) to substantially reduce the annual occupational equivalent dose limit for the ocular lens has now been adopted in the European Union and is under consideration around the rest of the world. However, ICRP clearly states that the recommendations are chiefly based on epidemiological evidence because there are a very small number of studies that provide explicit biological, mechanistic evidence at doses <2Gy...
October 2016: Mutation Research
https://www.readbyqxmd.com/read/27853010/femtosecond-laser-assisted-deep-anterior-lamellar-keratoplasty-with-big-bubble-technique-for-keratoconus
#2
Yan Lu, Xiangfei Chen, Liping Yang, Chunyan Xue, Zhenping Huang
PURPOSE: The purpose of this study was to evaluate the clinical results after deep anterior lamellar keratoplasty (DALK) assisted by the femtosecond laser with big-bubble technique for keratoconus. METHODS: A case series of 22 eyes in 19 patients with keratoconus was enrolled in the study. The 500-kHz VisuMax femtosecond laser (Carl Zeiss Meditec AG, Jena, Germany) was used to create a vertical side cut on donor and recipient corneas. Intraoperative and postoperative complications, uncorrected visual acuity, best-corrected visual acuity, corneal curvature, and central corneal thickness were evaluated in all patients...
September 2016: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/27843237/demonstration-of-cornea-dua-s-layer-at-a-deep-anterior-lamellar-keratoplasty-surgery
#3
Yusuf Koçluk, Ayşe Burcu, Emine Alyamaç Sukgen
The authors aimed to present a deep anterior lamellar keratoplasty (DALK) surgery case with mixed type bubble demonstrating Dua's layer (DL). This was a reported case of DALK surgery. The authors encountered cornea DL structure at DALK surgery while cleaning the remaining stromal pieces. We also observed perforation in the central part of DL. However, DALK surgery could be completed. It is possible to encounter DL in a DALK surgery performed with mixed type big-bubble.
September 2016: Oman Journal of Ophthalmology
https://www.readbyqxmd.com/read/27802912/systematic-review-comparing-penetrating-keratoplasty-and-deep-anterior-lamellar-keratoplasty-for-management-of-keratoconus
#4
REVIEW
Christin Henein, Mayank A Nanavaty
AIM: Perception of reduced incidence of graft rejection after deep anterior lamellar keratoplasty (DALK) has attracted many surgeons towards this technique in keratoconus. This review aims to compare the visual, refractive and graft outcomes after penetrating keratoplasty (PK) and DALK for keratoconus. METHODS: Electronic searches of PubMed, MEDLINE, EMBASE, Latin American and Caribbean Health Sciences Literature database (LILACS), metaRegister of Controlled Trials (mRCT), ClinicalTrial...
October 29, 2016: Contact Lens & Anterior Eye: the Journal of the British Contact Lens Association
https://www.readbyqxmd.com/read/27755187/macular-corneal-dystrophy-and-posterior-corneal-abnormalities
#5
Yair Rubinstein, Chen Weiner, Adi Einan-Lifshitz, Noa Chetrit, Nadav Shoshany, David Zadok, Isaac Avni, Eran Pras
PURPOSE: This study reports the presentation of 2 families with macular corneal dystrophy (MCD). The aim of this study was to show whether ultrasound biomicroscopy (UBM) can, based on posterior changes of the cornea in MCD, assist in the choice of surgery, either anterior lamellar keratoplasty (DALK) or penetrating keratoplasty (PK), compared with optical coherence tomography (OCT) and Scheimpflug. METHODS: Six patients with MCD were examined for their best-corrected visual acuity, slit-lamp, OCT, UBM, and Scheimpflug findings...
October 14, 2016: Cornea
https://www.readbyqxmd.com/read/27754782/amplitude-of-accommodation-in-schoolchildren
#6
Victor Delpizzo Castagno, Manuel Augusto Pereira Vilela, Rodrigo Dalke Meucci, Deiner Paulo Martins Resende, Francis Huszar Schneid, Rafael Getelina, Maurício Rodrigues Nasiloski, Anaclaudia Gastal Fassa
PURPOSE: Hofstetter's equations are based on studies of Amplitude of Accommodation (AA) with methodological limitations, particularly in the case of children younger than 10 years of age. The aim of this study is to evaluate AA by age, gender, economic status, and time of day as well as accommodative insufficiency prevalence. METHODS: A cross-sectional study was conducted with 867 schoolchildren aged 6-16 years attending two public schools in the urban area of the South Brazilian city of Pelotas...
October 18, 2016: Current Eye Research
https://www.readbyqxmd.com/read/27749448/cannula-dalk-versus-needle-dalk-for-keratoconus
#7
Enrica Sarnicola, Caterina Sarnicola, Francesco Sabatino, Gian M Tosi, Paolo Perri, Vincenzo Sarnicola
PURPOSE: To evaluate outcomes and possible advantages of 2 different techniques of deep anterior lamellar keratoplasty (DALK) in patients with keratoconus: cannula big-bubble DALK and needle big-bubble DALK (Anwar technique). METHODS: This is a retrospective, nonconsecutive, comparative study of 507 eyes affected by keratoconus that underwent DALK between 2002 and 2012. Needle DALK and cannula DALK techniques were performed in 266 eyes and 241 eyes, respectively...
October 5, 2016: Cornea
https://www.readbyqxmd.com/read/27749446/tectonic-descemet-stripping-automated-endothelial-keratoplasty-for-the-management-of-sterile-corneal-perforations-in-decompensated-corneas
#8
Yoav Nahum, Irit Bahar, Massimo Busin
PURPOSE: To report the use of Descemet stripping automated endothelial keratoplasty (DSAEK) for treatment of sterile corneal perforations accompanying endothelial decompensation. METHODS: In this multicenter interventional case series, we reviewed the medical records of all tectonic DSAEK surgeries performed at Villa Serena-Villa Igea private Hospitals (Forlì, Italy) and Rabin Medical Center (Petach Tikva, Israel) between January 2014 and March 2016. RESULTS: Three patients with endothelial decompensation and sterile corneal perforation (n = 2) or impending corneal perforation (n = 1) underwent DSAEK between 2014 and 2015 at Villa Igea Hospital, Forlì, Italy, and Rabin Medical Center, Petach Tikva, Israel...
October 5, 2016: Cornea
https://www.readbyqxmd.com/read/27688284/interface-infectious-keratitis-following-deep-anterior-lamellar-keratoplasty
#9
Shreesha Kumar Kodavoor, Ramamurthy Dandapani, Ajay Ramesh Kaushik
A 32-year-old female patient underwent deep anterior lamellar keratoplasty (DALK) in both eyes for advanced keratoconus. She developed an infiltrate in the nasal paracentral interface of the left eye. In view of the paracentral location, localized epithelial removal/stromal scraping was done and the infiltrate was removed using forceps and sent for microbiological assay, which revealed fungal filaments. The patient successfully responded to intensive topical antifungal therapy with the maintenance of visual acuity...
August 2016: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/27684823/clinical-evaluation-of-deep-anterior-lamellar-keratoplasty-using-glycerol-cryopreserved-corneal-tissues-for-refractory-herpetic-stromal-keratitis-an-observational-study
#10
Xin Liu, Qi Zhou, Xinyu Huang, Zhenxing Liu, Yanlong Bi
The study aimed to evaluate the therapeutic effects of deep anterior lamellar keratoplasty (DALK) using glycerol-cryopreserved corneal tissues (GCCTs) in patients with refractive herpes simplex keratitis (HSK). This article was a retrospective, noncomparative, and interventional case series. Patients with HSK underwent DALK using GCCTs at Shanghai Tongji Hospital from 2012 to 2015. The best spectacle corrected visual acuity, recurrent inflammation, graft status, postoperative central graft thickness, and pre/postoperative complications were detected...
September 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27519560/incidence-and-risk-factors-of-elevated-intraocular-pressure-following-deep-anterior-lamellar-keratoplasty
#11
Olivia S Huang, Jodhbir S Mehta, Hla M Htoon, Donald T Tan, Tina T Wong
PURPOSE: To report the incidence and risk factors of elevated IOP following deep anterior lamellar keratoplasty (DALK). DESIGN: A retrospective case series. METHODS: A retrospective study investigating the 5-year incidence of raised IOP following DALK cases performed from 2004 to 2008 in a tertiary center. Patients with less than 6 months of follow-up were excluded. Elevated IOP was defined as IOP >21 mm Hg. RESULTS: An episode of elevated IOP occurred in 36...
October 2016: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/27516677/non-drug-therapy-and-prevention-of-diabetes-mellitus-by-dalk-massage
#12
Davood Bayat, Seyed Reza Vakilinia, Majid Asghari
BACKGROUND: According to WHO estimation, the number of diabetic patients would reach about 591.9 million people in 2035. The tendency towards other kinds of treatment is increasing because of the high therapeutic expenditures and current medical complications. Positive results of massage in recent articles and the prominent role of dalk in Iranian traditional medicine led us to the present study review. METHODS: Studying Iranian traditional medicine textbooks, such as Canon of Ibn Sina, Kholasat Al Hekma of Aghili, Zakhireh-ye Khwarazm shahi of Jorjani, Alhavi of Razes and Kamel-al-sanaat of Ibn Abas were done on the topic of dalk discussion...
May 2016: Iranian Journal of Medical Sciences
https://www.readbyqxmd.com/read/27515168/intraoperative-optical-coherence-tomography-rescan-%C3%A2-700-for-detecting-iris-incarceration-and-iridocorneal-adhesion-during-keratoplasty
#13
Hiroshi Eguchi, Shunji Kusaka, Eiko Arimura-Koike, Kuniko Tachibana, Daishi Tsujioka, Masahiko Fukuda, Yoshikazu Shimomura
There is no report focusing on the visualization of the iris incarceration or the iridocorneal adhesion during keratoplasty by use of microscope-integrated intraoperative optical coherence tomography (MIOCT). The purpose of this study is to report the usefulness of MIOCT for detecting iris incarceration and iridocorneal adhesions during penetrating keratoplasty (PK) and deep anterior lamellar keratoplasty (DALK). MIOCT system was applied both in a patient who underwent PK for corneal leukoma and in a patient who underwent DALK for keratoconus...
August 11, 2016: International Ophthalmology
https://www.readbyqxmd.com/read/27491697/sequential-bilateral-corneal-transplantation-and-graft-survival
#14
Bernhard Steger, Elinor Curnow, Robert Cheeseman, Vito Romano, Abigail Kaye, Mark Jones, Stephen Kaye
PURPOSE: To investigate graft survival and rejection following sequential bilateral corneal transplantation. DESIGN: Retrospective cohort study. METHODS: The study included patients with Fuchs endothelial dystrophy (FED), pseudophakic bullous keratopathy (PBK), or keratoconus who had undergone a penetrating keratoplasty (PK), endothelial keratoplasty (EK), or deep anterior lamellar keratoplasty (DALK) between 1999 and 2012. The main cohort included patients who had received a first transplant in both eyes for the same indication and a control cohort patients who had undergone a unilateral first corneal transplant...
October 2016: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/27488912/four-years-of-corneal-keratoplasty-in-italian-paediatric-patients-indications-and-clinical-outcomes
#15
Luca Buzzonetti, Roberta Ardia, Sergio Petroni, Gianni Petrocelli, Paola Valente, Rosa Parrilla, Giancarlo Iarossi
PURPOSE: The purpose was to evaluate indications and clinical outcomes in paediatric corneal keratoplasty. METHODS: Fifty-four eyes of 43 patients who underwent corneal keratoplasty from the 1(st) of January 2010 through the 31(st) of December 2013 at the Bambino Gesù Children's Hospital in Rome, Italy, were retrospectively evaluated. To assess the effect of age on graft failure rate, the recipient age was considered as a dichotomous variable (≤5 or >5 years) and a 2X2 table was developed, using the chi-square test for testing the statistical significance...
August 3, 2016: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/27487442/-smoking-prevalence-and-associated-factors-among-tobacco-farmers-in-southern-brazil
#16
Nadia Spada Fiori, Neice Muller Xavier Faria, Rodrigo Dalke Meucci, Anaclaudia Gastal Fassa
This study aimed to describe the prevalence of smoking and associated factors in a cross-sectional population-based sample of 2,464 tobacco farmers in 2011. Multivariate analysis in men assessed the association between smoking and socioeconomic, behavioral, and occupational variables. Some 31.2% of men and 3.1% of women were current smokers. In men, smoking was directly associated with age, schooling, income, heavy drinking, time at work in tobacco farming, and time of exposure to pesticides. Employment relationship was a risk factor for smoking, and participation in religious activities was a protective factor...
August 1, 2016: Cadernos de Saúde Pública
https://www.readbyqxmd.com/read/27467039/precisely-controlled-side-cut-in-femtosecond-laser-assisted-deep-lamellar-keratoplasty-for-advanced-keratoconus
#17
Suxia Li, Ting Wang, Jiang Bian, Fuhua Wang, Shasha Han, Weiyun Shi
PURPOSE: To evaluate the outcomes of femtosecond laser-assisted deep lamellar keratoplasty (FDLK) in treating advanced keratoconus. METHODS: In the management of keratoconus in advanced stages, 89 patients (94 eyes) received FDLK, and 100 patients (100 eyes) underwent vacuum trephine-assisted deep anterior lamellar keratoplasty (DALK). Visual acuity, corneal curvature, and central corneal thickness were measured. The follow-up duration was 1 year. RESULTS: The best-corrected visual acuity (logMAR) was 0...
October 2016: Cornea
https://www.readbyqxmd.com/read/27442318/needle-depth-and-big-bubble-success-in-deep-anterior-lamellar-keratoplasty-an-ex-vivo-microscope-integrated-oct-study
#18
Neel D Pasricha, Christine Shieh, Oscar M Carrasco-Zevallos, Brenton Keller, David Cunefare, Jodhbir S Mehta, Sina Farsiu, Joseph A Izatt, Cynthia A Toth, Anthony N Kuo
PURPOSE: To examine big-bubble (BB) formation success rates in deep anterior lamellar keratoplasty (DALK) at various corneal depths using real-time guidance from swept-source, microscope-integrated optical coherence tomography (SS-MIOCT). METHODS: The DALK procedure was performed ex vivo with 34 human donor corneoscleral buttons on pressurized artificial anterior chambers using the BB technique employed by Anwar and Teichmann. We inserted a needle under controlled ex vivo conditions to corneal depths ranging from 40% to ≥90% using real-time guidance from SS-MIOCT and injected air...
November 2016: Cornea
https://www.readbyqxmd.com/read/27436117/-intraoperative-optical-coherence-tomography-in-corneal-and-glaucoma-surgical-procedures
#19
S Siebelmann, B Bachmann, A Lappas, T Dietlein, M Hermann, S Roters, C Cursiefen, P Steven
BACKGROUND: Optical coherence tomography (OCT) is the clinical gold standard for anterior and posterior segment imaging. Since OCT devices have been integrated into surgical microscopes, this technique is also available intraoperatively in anterior segment surgery. OCT is well established in imaging very thin or transparent structures as they appear in corneal or glaucoma surgery. Therefore, intraoperative OCT can deliver important information for the surgeon which is superior to the normal surgical microscope...
August 2016: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
https://www.readbyqxmd.com/read/27435994/corrosion-casts-of-big-bubbles-formed-during-deep-anterior-lamellar-keratoplasty
#20
Sepehr Feizi, Mozhgan Rezaei Kanavi, Davood Kharaghani, Sahar Balagholi, Masoumeh Meskinfam, Mohammad Ali Javadi
PURPOSE: To characterize the walls of big bubbles formed during deep anterior lamellar keratoplasty (DALK) using the corrosion casting technique. METHODS: Fresh corneoscleral buttons with normal transparency and without any known eye diseases (n = 11) were obtained from 11 human donors. A 20-gauge needle was used to inject a solution of 20 % polyvinyl alcohol (PVA) immediately beneath the corneal endothelium to form big bubbles in eight corneoscleral buttons...
July 19, 2016: Japanese Journal of Ophthalmology
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