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Nutrition cirrhosis

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https://www.readbyqxmd.com/read/30312295/the-prognostic-value-of-prognostic-nutritional-index-in-hepatocellular-carcinoma-patients-a-meta-analysis-of-observational-studies
#1
Zhiling Wang, Jie Wang, Peijun Wang
BACKGROUND AND AIMS: The clinical value of the prognostic nutritional index (PNI) in hepatocellular carcinoma (HCC) has been investigated in previous studies, but the results remain controversial. Here we present a meta-analysis to systematically review the association between PNI and HCC prognosis. METHOD: PubMed, EMBASE, Web of Science databases were systematically searched to identify relevant studies. Data were abstracted independently by two reviewers. A meta-analysis was performed to determine the prognostic and clinic-pathological values of PNI in HCC patients...
2018: PloS One
https://www.readbyqxmd.com/read/30292583/dietary-management-and-supplementation-with-branched-chain-amino-acids-in-cirrhosis-of-the-liver
#2
A Ruiz-Margáin, O Méndez-Guerrero, B M Román-Calleja, S González-Rodríguez, G Fernández-Del-Rivero, P A Rodríguez-Córdova, A Torre, R U Macías-Rodríguez
One of the most important characteristics of malnutrition is the loss of muscle mass and the severe depletion of the protein reserve, secondarily affecting energy metabolism. That impacts nutritional status and the progression of disease-related complications. Nutritional treatment is one of the main factors in the comprehensive management of those patients. Achieving adequate energy intake that provides the macronutrients and micronutrients necessary to prevent or correct malnutrition is attempted through dietary measures...
October 3, 2018: Revista de Gastroenterología de México
https://www.readbyqxmd.com/read/30288329/racial-ethnic-and-county-specific-prevalence-of-chronic-hepatitis-b-and-its-burden-in-california
#3
Mehlika Toy, Bin Wei, Tejpal S Virdi, An Le, Huy Trinh, Jiayi Li, Jian Zhang, Ann W Hsing, Samuel K So, Mindie H Nguyen
Background: In the United States, the highest burden of chronic hepatitis B (CHB) and CHB-related liver cancer is in the state of California, primarily in the San Francisco (SF) Bay and Los Angeles (LA) areas. The aim of this study was to estimate county-specific hepatitis B surface antigen (HBsAg) prevalence and quantify CHB cases by age, race/ethnicity, nativity, and disease activity status. Methods: Twelve counties in SF Bay Area and three large counties in LA area were included for this analysis...
2018: Hepatology, Medicine and Policy
https://www.readbyqxmd.com/read/30272092/usefulness-of-simplified-nutritional-appetite-questionnaire-snaq-in-appetite-assessment-in-elder-patients-with-liver-cirrhosis
#4
T Wang, J Shen
BACKGROUND: Appetite has received little attention in health care and researches in liver cirrhosis. The Simplified Nutritional Appetite Questionnaire (SNAQ), a self-assessment nutritional screening tool, could be used to screen the risk of malnutrition and weight loss. Our objective was to assess the usefulness of SNAQ in appetite assessment in patients with liver cirrhosis. METHODS: Seventy patients were enrolled. Appetite assessment was applied in the enrolled patients by completing SNAQ...
2018: Journal of Nutrition, Health & Aging
https://www.readbyqxmd.com/read/30259203/should-sarcopenia-increase-priority-for-transplant-or-is-it-a-contraindication
#5
REVIEW
Guido Stirnimann, Maryam Ebadi, Puneeta Tandon, Aldo J Montano-Loza
PURPOSE OF REVIEW: The purpose of this review is to discuss the current evidence regarding the impact of sarcopenia on patients with cirrhosis awaiting liver transplantation and to determine if its presence should be considered a criterion for expedited transplantation or a contraindication for transplantation. RECENT FINDINGS: Sarcopenia is a negative predictor of survival in patients on a waiting list and after liver transplant. The gut-liver axis and the liver-muscle axis have been explored to understand the complex pathophysiology of sarcopenia...
September 26, 2018: Current Gastroenterology Reports
https://www.readbyqxmd.com/read/30244656/the-benefit-of-supplemental-nutrition-education-for-severely-malnourished-patients-awaiting-liver-transplant
#6
Amanda J Chaney, Michael G Heckman
INTRODUCTION: Nutritional interventions improve patient outcomes and reduce mortality in patients with cirrhosis by reducing infection risk, ascites, length of stay in hospital and intensive care unit, and mortality. Follow-up phone calls have been found to be useful in improving patient adherence to therapy. PROBLEM: The purpose of this quality improvement project was to determine whether supplemental nutrition education would improve nutrition and outcomes among patients with cirrhosis who are undergoing a liver transplant evaluation...
September 24, 2018: Progress in Transplantation
https://www.readbyqxmd.com/read/30180152/pretransplant-sarcopenia-in-patients-with-nash-cirrhosis-does-not-impact-rehospitalization-or-mortality
#7
Elizabeth S Aby, Edward Lee, Satvir S Saggi, Matthew R Viramontes, Jonathan F Grotts, Vatche G Agopian, Ronald W Busuttil, Sammy Saab
BACKGROUND: Malnutrition and muscle wasting are common in patients with end-stage liver disease (ESLD), yet go underdiagnosed. Frequently used indices of nutritional status, such as body mass index, are inflated in patients with ESLD due to a fluid overloaded state. Previous work has demonstrated a strong association between psoas muscle area, a surrogate for sarcopenia, and worse survival following liver transplantation; however, the impact of sarcopenia on post liver transplant outcomes in patients with nonalcoholic steatohepatitis (NASH) cirrhosis has not been evaluated...
September 1, 2018: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/30158477/the-relationship-between-controlling-nutritional-conut-score-and-clinical-markers-among-adults-with-hepatitis-c-virus-related-liver-cirrhosis
#8
Hiroki Nishikawa, Kazunori Yoh, Hirayuki Enomoto, Noriko Ishii, Yoshinori Iwata, Ryo Takata, Takashi Nishimura, Nobuhiro Aizawa, Yoshiyuki Sakai, Naoto Ikeda, Kunihiro Hasegawa, Tomoyuki Takashima, Hiroko Iijima, Shuhei Nishiguchi
AIMS: To identify the relationship between the Controlling Nutrition Status (CONUT) score and clinical parameters among adults with hepatitis C virus (HCV)-related liver cirrhosis (LC) ( n = 264, 141 males and 123 females). METHODS: The relationship between the CONUT score and clinical variables such as Child-Pugh classification were investigated. We also examined factors linked to poor nutritional state as determined by CONUT score. RESULTS: According to the CONUT score, normal nutritional state was found in 57 patients, mild malnutrition state in 132, moderate malnutrition state in 68 and severe malnutrition state in 7...
August 29, 2018: Nutrients
https://www.readbyqxmd.com/read/30153225/international-liver-transplantation-consensus-statement-on-end-stage-liver-disease-due-to-nonalcoholic-steatohepatitis-and-liver-transplantation
#9
Emmanuel Tsochatzis, Audrey Coilly, Silvio Nadalin, Josh Levistky, Yaman Tokat, Mark Ghobrial, John Klinck, Marina Berenguer
Nonalcoholic steatohepatitis (NASH)-related cirrhosis has become one of the most common indications for liver transplantation (LT), particularly in candidates over the age of 65 years. Typically, NASH candidates have concurrent obesity, metabolic and cardiovascular risks, which directly impact patient evaluation and selection, waitlist morbidity and mortality and eventually posttransplant outcomes. The purpose of these guidelines is to highlight specific features commonly observed in NASH candidates and strategies to optimize pretransplant evaluation and waitlist survival...
August 27, 2018: Transplantation
https://www.readbyqxmd.com/read/30144956/easl-clinical-practice-guidelines-on-nutrition-in-chronic-liver-disease
#10
(no author information available yet)
A frequent complication in liver cirrhosis is malnutrition, which is associated with the progression of liver failure, and with a higher rate of complications including infections, hepatic encephalopathy and ascites. In recent years, the rising prevalence of obesity has led to an increase in the number of cirrhosis cases related to non-alcoholic steatohepatitis. Malnutrition, obesity and sarcopenic obesity may worsen the prognosis of patients with liver cirrhosis and lower their survival. Nutritional monitoring and intervention is therefore crucial in chronic liver disease...
August 22, 2018: Journal of Hepatology
https://www.readbyqxmd.com/read/30122874/nutritional-issues-in-patients-with-obesity-and-cirrhosis
#11
REVIEW
Luigi Schiavo, Luca Busetto, Manuela Cesaretti, Shira Zelber-Sagi, Liat Deutsch, Antonio Iannelli
Obesity and metabolic syndrome are considered as responsible for a condition known as the non-alcoholic fatty liver disease that goes from simple accumulation of triglycerides to hepatic inflammation and may progress to cirrhosis. Patients with obesity also have an increased risk of primary liver malignancies and increased body mass index is a predictor of decompensation of liver cirrhosis. Sarcopenic obesity confers a risk of physical impairment and disability that is significantly higher than the risk induced by each of the two conditions alone as it has been shown to be an independent risk factor for chronic liver disease in patients with obesity and a prognostic negative marker for the evolution of liver cirrhosis and the results of liver transplantation...
August 14, 2018: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/30057519/ischemic-duodenal-ulceration-after-transarterial-chemoembolization-for-hepatocellular-carcinoma-a-case-report
#12
Natascha Roehlen, Richard F Knoop, Katharina Laubner, Jochen Seufert, Henning Schwacha, Robert Thimme, Andreas Fischer
Drug-eluting bead transarterial chemoembolization (DEB-TACE) is a well-established, minimally invasive interventional treatment for nonresectable hepatocellular carcinoma (HCC). Generally, TACE is regarded as safe and effective with a low complication rate. However, remote gastrointestinal ischemia due to the carryover of embolic material into visceral arteries is a rare but serious complication of TACE. In this report, we present a case of duodenal ulceration with contained perforation and severe necrotizing pancreatitis after TACE in a patient with nonresectable HCC and underlying hepatitis C virus associated with Child-Pugh stage B liver cirrhosis...
May 2018: Case Reports in Gastroenterology
https://www.readbyqxmd.com/read/30051372/prognostic-significance-of-preoperative-controlling-nutritional-status-conut-score-in-patients-undergoing-hepatic-resection-for-hepatocellular-carcinoma-a-multi-institutional-study
#13
Norifumi Harimoto, Tomoharu Yoshizumi, Shoichi Inokuchi, Shinji Itoh, Eisuke Adachi, Yasuharu Ikeda, Hideaki Uchiyama, Tohru Utsunomiya, Kiyoshi Kajiyama, Koichi Kimura, Fumiaki Kishihara, Keishi Sugimachi, Eiji Tsujita, Mizuki Ninomiya, Kengo Fukuzawa, Takashi Maeda, Ken Shirabe, Yoshihiko Maehara
BACKGROUND: The Controlling Nutritional Status (CONUT) score is an objective tool that is widely used to assess the nutritional status in patients, including those with cancer. The relationship between the CONUT score and prognosis in patients who have undergone hepatic resection has not been evaluated in a multi-institutional study. METHODS: Data were retrospectively collected for 2461 consecutive patients with hepatocellular carcinoma (HCC) who had undergone hepatic resection with curative intent at 13 institutions between January 2004 and December 2015...
October 2018: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/30018475/liver-transplantation-and-alcoholic-liver-disease-history-controversies-and-considerations
#14
REVIEW
Claudio Augusto Marroni, Alfeu Medeiros Fleck, Sabrina Alves Fernandes, Lucas Homercher Galant, Marcos Mucenic, Mario Henrique de Mattos Meine, Guilherme Mariante-Neto, Ajacio Bandeira de Mello Brandão
Alcohol consumption accounts for 3.8% of annual global mortality worldwide, and the majority of these deaths are due to alcoholic liver disease (ALD), mainly alcoholic cirrhosis. ALD is one of the most common indications for liver transplantation (LT). However, it remains a complicated topic on both medical and ethical grounds, as it is seen by many as a "self-inflicted disease". One of the strongest ethical arguments against LT for ALD is the probability of relapse. However, ALD remains a common indication for LT worldwide...
July 14, 2018: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/29994872/refeeding-syndrome-in-the-gastroenterology-practice-how-concerned-should-we-be
#15
Gonçalo Nunes, Mariana Brito, Carla Adriana Santos, Jorge Fonseca
Clinical nutrition is emerging as a major area in gastroenterology practice. Most gastrointestinal disorders interfere with digestive physiology and compromise nutritional status. Refeeding syndrome (RS) may increase morbidity and mortality in gastroenterology patients. Literature search using the keywords "Refeeding Syndrome", "Hypophosphatemia", "Hypomagnesemia" and "Hypokalemia". Data regarding definition, pathophysiology, clinical manifestations, risk factors, management and prevention of RS were collected...
November 2018: European Journal of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/29974779/malnutrition-is-a-key-prognostic-factor-related-to-high-mortality-rate-in-patients-with-severe-alcoholic-hepatitis
#16
Fátima Higuera-de la Tijera, Alfredo Servín-Caamaño, Luis Servìn-Abad, José Luis Pérez-Hernández
BACKGROUND AND AIM: comparatively with European or North-American populations, severe alcoholic hepatitis has a high mortality rate in Mexican population, becoming as high as 50 to 81% in those classified as ABIC B or C; this is true even when they receive specific therapy with steroids or pentoxifylline. The aim of this study was to know which clinical factors are related to early mortality (first 30 days) in Mexican patients with severe alcoholic hepatitis. SUBJECTS AND METHODS: this was a retrospective cohort study that included patients with severe alcoholic hepatitis, defined by a Maddrey's discriminant function ≥ 32, treated at a tertiary care center in a period of five years (2010 to 2015)...
May 17, 2018: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://www.readbyqxmd.com/read/29973706/refractory-ascites-in-liver-cirrhosis
#17
REVIEW
Danielle Adebayo, Shuet Fong Neong, Florence Wong
Ascites, a common complication of liver cirrhosis, eventually becomes refractory to diuretic therapy and sodium restriction in ~10% of patients. Multiple pathogenetic factors are involved in the development of refractory ascites, which ultimately lead to renal hypoperfusion and avid sodium retention. Therefore, renal dysfunction commonly accompanies refractory ascites. Management includes continuation of sodium restriction, which needs frequent reviews for adherence; and regular large volume paracentesis of 5 L or more with albumin infusions to prevent the development of paracentesis-induced circulatory dysfunction...
July 5, 2018: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/29964066/exercise-in-cirrhosis-translating-evidence-and-experience-to-practice
#18
REVIEW
Puneeta Tandon, Kathleen Patricia Ismond, Kenneth Riess, Andres Duarte-Rojo, Bandar Al-Judaibi, Michael Andrew Dunn, Jennifer Holman, Nancy Howes, Mark Joseph Franklin Haykowsky, Deborah Ann Josbeno, Margaret McNeely
Physical inactivity, sarcopenia, and frailty are highly prevalent, independent predictors of morbidity and mortality in patients with cirrhosis. Across a range of chronic diseases, exercise training is a key recommendation supported by guidelines and, for some conditions, even by governmental funding of exercise programmes. Consistent with the broader chronic disease literature, the evidence for a benefit of exercise in cirrhosis is promising. Several small trials have reported significant improvements in muscle health (mass, strength, functional capacity), quality of life, fatigue, and reductions in the hepatic venous pressure gradient, without adverse events...
June 30, 2018: Journal of Hepatology
https://www.readbyqxmd.com/read/29915268/low-circulating-chemerin-levels-correlate-with-hepatic-dysfunction-and-increased-mortality-in-decompensated-liver-cirrhosis
#19
Paul Horn, Christian von Loeffelholz, Franziska Forkert, Sven Stengel, Philipp Reuken, René Aschenbach, Andreas Stallmach, Tony Bruns
Nutritional status, infections, inflammation and extrahepatic organ dysfunction are critical factors for the progression of chronic liver disease. Chemerin is an immune-metabolically and chemotactically active adipokine and we hypothesized that it is associated with disease severity and prognosis in patients with advanced decompensated cirrhosis. Therefore, we measured serum concentrations of chemerin in a prospectively characterized cohort of 80 patients with decompensated cirrhosis and ascites and assessed the associations with markers of disease severity and short-term outcome at 28 days...
June 18, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29912757/dietary-interventions-in-liver-cirrhosis
#20
Chu Kion Yao, James Fung, Natural Hoi Sing Chu, Victoria Ping Yi Tan
Liver cirrhosis is associated with significant nutritional risks that often result in serious hepatic complications and poor survival rates. Diet is an important but underutilized aspect in the treatment modality of cirrhosis. Therefore, the aims of this review are to ascertain nutritional risks associated with its pathophysiology and to summarize existing evidence that support dietary recommendations for managing this patient population. Alterations in substrate utilization for energy production is a main feature of liver cirrhosis, resulting in increased catabolism of protein stores and a predisposition toward protein-energy malnutrition, even in the early stages of the disease...
September 2018: Journal of Clinical Gastroenterology
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