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https://www.readbyqxmd.com/read/29750128/clinicohistopathological-characteristics-of-malignant-melanoma-in-the-gall-bladder-a-case-report-and-review-of-the-literature
#1
Schmidt Adrian, Caspar Clemens, Schmidt-Weiss Elisabeth, Stadlmann Sylvia
Objective: Primary gall bladder melanoma is a rare and controversial entity. So far, only 36 cases are documented in the literature. Metastatic melanoma targeting the gall bladder, however, has been reported to occur in about 15-20% of melanoma patients and is much more common. Methods: Based on the case of a 58-year-old woman presenting with multiple melanoma nodules in the gall bladder, we searched in the available literature in PubMed for articles describing a "primary melanoma of the gallbladder" regardless of language used...
2018: Case Reports in Pathology
https://www.readbyqxmd.com/read/29737313/laparoscopic-management-of-a-case-of-accessory-gall-bladder-with-review-of-literature
#2
Guru Prasad Painuly, Ankur Gupta, Mini Singhal, Bhavna Bansal
Gall bladder duplication is a rare congenital anomaly. True duplication is still rarer. Pre-operative detection helps in avoiding complications or missing the gall bladder during surgery. Ultrasonography (USG) and magnetic resonance cholangiography are investigation of choice. Laparoscopic cholecystectomy is the preferred modality for management of double gall bladder. We present a case diagnosed as cholelithiasis on USG. While doing laparoscopic surgery 2 gall bladders were found. She had a normal gall bladder that was lying in the supraduodenal area...
May 4, 2018: Journal of Minimal Access Surgery
https://www.readbyqxmd.com/read/29727803/synchronous-double-primary-cancers-of-the-extrahepatic-bile-duct-a-case-report-and-literature-review
#3
Takeshi Nishi, Yoshitoshi Sato, Takuya Hanaoka, Takuya Takahashi, Hiroshi Miura, Kenji Takubo
BACKGROUND: Double cancers of the biliary tract system are rare. Most of these cancers are synchronous double cancers of the gall bladder and bile duct, associated with pancreaticobiliary maljunction (PBM). Synchronous double cancers of the extrahepatic bile duct without PBM are especially rare, and only 4 cases have been reported. CASE PRESENTATION: A 78-year-old woman was admitted to our hospital for examination of hyperbilirubinemia and liver dysfunction. Contrast-enhanced abdominal computed tomography, Magnetic resonance cholangiopancreatography and endoscopic retrograde cholangiopancreatography revealed 2 stenotic regions in the common bile duct: at its junction with the cystic duct and in the distal bile duct...
April 27, 2018: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/29721656/effects-of-miconazole-clotrimazole-and-praziquantel-combinations-against-the-liver-fluke-opisthorchis-felineus-in-vivo-and-in-vitro
#4
Maria Y Pakharukova, Yuri V Pakharukov, Viatcheslav A Mordvinov
The liver fluke Opisthorchis felineus (Rivolta, 1884) is the causative agent of opisthorchiasis felinea in Eurasia. Opisthorchiasis is a serious human and fish-eating animal's disease affecting bile ducts and the gall bladder. Currently, the main drug for specific therapy of opisthorchiasis is praziquantel. We have previously shown that azole inhibitors of O. felineus cytochrome P450 significantly reduced survival of the worms in vitro. Here, we studied in vitro anthelmintic effects of drug combinations involving azole substances approved by the US Food and Drug Administration together with praziquantel against adult or juvenile O...
May 2, 2018: Parasitology Research
https://www.readbyqxmd.com/read/29705976/feasibility-study-of-postoperative-adjuvant-chemotherapy-with-s-1-in-patients-with-biliary-tract-cancer
#5
Kohei Nakachi, Masaru Konishi, Masafumi Ikeda, Kazuaki Shimada, Takuji Okusaka, Akio Saiura, Hiroshi Ishii, Masanori Sugiyama, Junji Furuse, Hirohiko Sakamoto, Tomotaka Shimamura, Takehiro Ohta
BACKGROUND: The role of adjuvant chemotherapy has not yet been established for patients with resected biliary tract cancer. S-1 has been shown to exert activity against advanced biliary tract cancer. Therefore, we evaluated the feasibility of adjuvant chemotherapy with S-1 in patients with resected biliary tract cancer. METHODS: Patients with complete macroscopic resection of intrahepatic/extrahepatic bile duct, gall bladder, or ampullary cancer were eligible. S-1 was administered orally twice daily for 4 weeks every 6 weeks, up to 4 cycles...
April 28, 2018: International Journal of Clinical Oncology
https://www.readbyqxmd.com/read/29669131/effect-of-dietary-fructooligosaccharide-supplementation-on-internal-organs-salmonella-colonization-immune-response-ileal-morphology-and-ileal-immunohistochemistry-in-laying-hens-challenged-with-salmonella-enteritidis
#6
Pratima Adhikari, Douglas E Cosby, Nelson A Cox, Monique S Franca, Susan M Williams, Robert M Gogal, Casey W Ritz, Woo K Kim
A study was conducted to evaluate the efficacy of fructooligosaccharides (FOS) in controlling the infection of Salmonella Enteritidis (SE) in White Leghorns. A total of 30 laying hens (white leghorns W-36) were challenged both orally and cloacally with approximately 108 colony-forming units of nalidxic acid resistant SE (SENAR) and divided into 3 treatments: 1) SENAR challenged + 0.0% FOS, 2) SENAR challenged + 0.5% FOS (Nutraflora), and 3) SENAR challenged + 1.0% FOS. SENAR recovery via fecal shedding was measured at 3- and 6-d post-infection (dpi), whereas in the ceca and internal organs, SENAR recovery was measured at 7-d post-infection...
April 13, 2018: Poultry Science
https://www.readbyqxmd.com/read/29650819/-a-case-report-of-neuroendocrine-carcinoma-in-the-gall-bladder-showing-recurrence-shortly-after-surgery
#7
Yoshihiro Uchino, Sonofu Taketani, Nobuhisa Hirayu, Koji Shiota, Hironobu Sou, Satoshi Taniwaki, Tetsuo Imamura
A55 -year-old woman with a 10×8mm protuberant gallbladder lesion visited our hospital. To determine possible malignancy, she underwent laparoscopic excision biopsy of the gallbladder, and pathological findings revealed an endocrine carcinoma in the gallbladder. Surgery involved extrahepatic bile duct resection, gallbladder bed resection, and hepatic portal lymph node resection. Recurrence in the peritoneal lymph node was observed in the early postoperative period. Chemotherapy was initiated with cisplatin and irinotecan, and continues 18 months post-operatively...
April 2018: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/29649951/biliary-ascariasis-presenting-with-gangrenous-perforation-of-the-gall-bladder-report-of-a-case-and-brief-review-of-literature
#8
Ankush Sharma, Priyansh Jariwala, Navneet Kaur
The most common cause of gallbladder perforation is calculous cholecystitis. Rarer causes include trauma, iatrogenic injuries, biliary stasis and gall bladder ischemia. We report a case of gall bladder gangrene with perforation, secondary to extensive ascariasis. A 45-year-old woman presented with acute intestinal obstruction and jaundice. She had abdominal distension and right hypochondrial tenderness. Abdominal radiography showed dilated bowel loops and ultrasonogram showed worms in the small intestine and biliary tree...
January 1, 2018: Tropical Doctor
https://www.readbyqxmd.com/read/29643880/intra-operative-predictors-of-difficult-cholecystectomy-and-conversion-to-open-cholecystectomy-a-new-scoring-system
#9
Nauman Ahmed, Maaz Ul Hassan, Maham Tahira, Abdul Samad, Hamad Naeem Rana
Objective: To evaluate the intra-operative scoring system to predict difficult cholecystectomy and conversion to open surgery. Methods: This descriptive study was conducted from March 2016 to August, 2016 in the Department of Surgery, Shalimar Hospital. The study recruited 120 patients of either gender, age greater than 18 years and indicated for laparoscopic cholecystectomy (LC). Intra-operatively all patients were evaluated using the new scoring system. The scoring system included five aspects; appearance and adhesion of Gall Bladder (GB), distension or contracture degree of GB, ease in access, local or septic complications, and time required for cystic artery and duct identification...
January 2018: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/29643654/role-of-endoscopic-ultrasound-guided-fine-needle-aspiration-in-adrenal-lesions-analysis-of-32-patients
#10
Rakesh K Gupta, Kaushik Majumdar, Ravindra K Saran, Siddharth Srivastava, Puja Sakhuja, Vineeta V Batra
Objective: Endoscopic ultrasound-guided fine-needle aspiration cytology (EUS-FNAC) is a precise and safe technique that provides both radiological and pathological diagnosis with a better diagnostic yield and minimal adverse events. EUS-FNAC led to the remarkable increase in the detection rate of incidentaloma found during radiologic staging or follow-up in various malignancy or unrelated conditions. Aims: We did this preliminary study with an aim to evaluate the role of EUS-FNA in diagnosing and classifying adrenal lesions, clinical impact, and compare the outcome with the previously published literature...
April 2018: Journal of Cytology
https://www.readbyqxmd.com/read/29624571/frequency-and-characteristics-of-gallbladder-cancer-at-a-referral-hospital-in-southern-peru-2009-2014-a-descriptive-study
#11
Tessy Tairo-Cerron, Richar Paredes-Orue, Oscar Moreno-Loaiza
INTRODUCTION: Gallbladder cancer is a rare neoplasm, its frequency is variable in the regions of Peru. OBJECTIVE: To determine the frequency and describe the clinical characteristics of gallbladder cancer in southern Peru. METHODS: The reports of the anatomopathological department of the Honorio Delgado Regional Hospital were selected from all samples of cholecystectomies performed between 2009 and 2014 and those that had some result compatible with gallbladder cancer were looked for...
March 26, 2018: Medwave
https://www.readbyqxmd.com/read/29600421/combined-robot-assisted-right-partial-nephrectomy-and-cholecystectomy-with-single-docking
#12
Konstantinos Stravodimos, Ioannis Katafigiotis, Christos Pournaras, Dimitrios Dimitroulis, Georgios Kousournas, Evangelos Fragkiadis, Constantinos Constantinides
ΑBSTRACT: We report the first case of robot-assisted partial nephrectomy (RARN) and Robot assisted cholecystectomy in a 66 years old female overweight patient with organ-confined right kidney tumor identified on the investigation of gastrointestinal symptoms with a single docking. A modified position of the patient and a slight altered placement of the trocars made feasible the concomitant performance of the two operations. Total blood loss was 80 ml, operation time was 253 min and console time 187 min...
March 29, 2018: Journal of Robotic Surgery
https://www.readbyqxmd.com/read/29597141/preliminary-evaluation-of-18-f-labeled-llp2a-trifluoroborate-conjugates-as-vla-4-%C3%AE-4-%C3%AE-1-integrin-specific-radiotracers-for-pet-imaging-of-melanoma
#13
Áron Roxin, Chengcheng Zhang, Sungjoon Huh, Mathieu L Lepage, Zhengxing Zhang, Kuo-Shyan Lin, François Bénard, David M Perrin
INTRODUCTION: The transmembrane α4 β1 integrin receptor, or very-late antigen 4 (VLA-4), is associated with tumor metastasis and angiogenesis, the development of chemotherapeutic drug resistance, and is overexpressed in multiple myelomas, osteosarcomas, lymphomas, leukemias, and melanomas. The peptidomimetic, LLP2A, is a high-affinity ligand with specificity for the extracellular portion of VLA-4 and several conjugates have been evaluated in vivo by NIR-fluorescence,111 In-SPECT and68 Ga- and64 Cu-PET imaging, but to date, not with18 F-PET...
March 12, 2018: Nuclear Medicine and Biology
https://www.readbyqxmd.com/read/29577030/eus-guided-gall-bladder-drainage-in-severe-liver-disease-a-single-center-experience-in-critically-ill-cirrhotics
#14
Kapil Dev Jamwal, Manoj Kumar Sharma, Rakhi Maiwall, Barjesh Kumar Sharma, Shiv Kumar Sarin
Background and Aims : Acute calculous cholecystitis with impending gall bladder perforation in severe liver diseases including decompensated cirrhosis and acute-on-chronic liver failure (ACLF) is difficult to manage, due to the procedures such as cholecystectomy and per cutaneous cholecystostomy being associated with high risk and complications in these patients. Methods : Four cases of severe liver disease with acute calculous cholecystitis who presented to the Institute of Liver and Biliary Sciences (New Delhi, India) for further management were included in the study if they underwent endoscopic ultrasound-guided gall bladder drainage (EUS-GBD)...
March 28, 2018: Journal of Clinical and Translational Hepatology
https://www.readbyqxmd.com/read/29571677/abdominal-pain-caused-by-a-second-gall-bladder-and-separate-cystic-duct
#15
Nayana George, Saikiran Raghavapuram, Abhilash Perisetti
No abstract text is available yet for this article.
March 21, 2018: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29561884/life-in-a-rock-pool-radiation-and-population-genetics-of-myxozoan-parasites-in-hosts-inhabiting-restricted-spaces
#16
Pavla Bartošová-Sojková, Alena Lövy, Cecile C Reed, Martina Lisnerová, Tereza Tomková, Astrid S Holzer, Ivan Fiala
INTRODUCTION: Intertidal rock pools where fish and invertebrates are in constant close contact due to limited space and water level fluctuations represent ideal conditions to promote life cycles in parasites using these two alternate hosts and to study speciation processes that could contribute to understanding the roles of parasitic species in such ecosystems. MATERIAL AND METHODS: Gall bladder and liver samples from five clinid fish species (Blenniiformes: Clinidae) were morphologically and molecularly examined to determine the diversity, prevalence, distribution and host specificity of Ceratomyxa parasites (Cnidaria: Myxozoa) in intertidal habitats along the coast of South Africa...
2018: PloS One
https://www.readbyqxmd.com/read/29541567/recurrent-biliary-obstruction-secondary-to-portal-biliopathy-and-the-role-of-cholagioscopy-a-case-report
#17
Agazi Gebreselassie, Majidah Bukhari, Ahmad Awan, Mouen Khashab
Portal vein thrombosis with cavernous transformation is a rare cause of biliary obstruction. Portal biliopathy is a term that refers to abnormalities in the intrahepatic and extrahepatic biliary tract, gall bladder, and cystic duct secondary to portal hypertension. Patients may be asymptomatic, but they can also present with abdominal pain, jaundice, and fever. We present the case of a 61-year-old Caucasian female who presented with generalized weakness, dark urine, and yellow skin for three days' duration...
January 9, 2018: Curēus
https://www.readbyqxmd.com/read/29541144/retracted-psorinum-therapy-in-treating-stomach-gall-bladder-pancreatic-and-liver-cancers-a-prospective-clinical-study
#18
Evidence-Based Complementary And Alternative Medicine
[This retracts the article DOI: 10.1155/2011/724743.].
2018: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/29536054/management-of-residual-gall-bladder-a-15-year-experience-from-a-north-indian-tertiary-care-centre
#19
Ashish Singh, Abhimanyu Kapoor, Rajneesh Kumar Singh, Anand Prakash, Anu Behari, Ashok Kumar, Vinay Kumar Kapoor, Rajan Saxena
Backgrounds/Aims: A residual gallbladder (RGB) following a partial/subtotal cholecystectomy may cause symptoms that require its removal. We present our large study regarding the problem of a RGB over a 15 year period. Methods: This study involved a retrospective analysis of patients managed for symptomatic RGB from January 2000 to December 2015. Results: A RGB was observed in 93 patients, who had a median age of 45 (25-70) years, and were comprised of 69 (74...
February 2018: Annals of Hepato-Biliary-Pancreatic Surgery
https://www.readbyqxmd.com/read/29527009/phase-ii-study-of-everolimus-rad001-monotherapy-as-first-line-treatment-in-advanced-biliary-tract-cancer-with-biomarker-exploration-the-radichol-study
#20
David K Lau, Rebecca Y Tay, Yvonne H Yeung, Fiona Chionh, Jennifer Mooi, Carmel Murone, Effie Skrinos, Timothy J Price, John M Mariadason, Niall C Tebbutt
BACKGROUND: Advanced biliary tract cancers (BTCs) have a poor prognosis and limited treatment options. This exploratory phase II study aimed to evaluate the activity of the mTOR inhibitor everolimus in advanced BTC and explore prognostic biomarkers. METHODS: Patients with advanced BTCs, who had not received chemotherapy for advanced disease, were enroled to receive everolimus (10 mg daily). The primary endpoint was disease control rate (DCR) at 12 weeks. Secondary endpoints included overall response rate, progression-free survival (PFS), overall survival (OS) and adverse events...
April 2018: British Journal of Cancer
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