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https://www.readbyqxmd.com/read/30116126/respiratory-syncytial-vir%C3%A3-s-infections-in-neonates-and-infants
#1
REVIEW
Yıldız Perk, Mine Özdil
Respiratory syncytial virus is one of the major causes of respiratory tract infections during infancy with high rates of hospitalization and mortality during the first years of life. It is the most common cause of acute bronchiolitis and viral pneumonia in children below two years of age and second the most common cause of postneonatal infant mortality all around the world following malaria. In addition, the virus has been causally linked to recurrent wheezing and associated with pediatric asthma. The respiratory syncytial virus infections tend to be severe in high risk patients such as patients below six months of age, with prematurity, congenital heart diseases, neuromuscular diseases and immune deficiencies...
June 2018: Türk Pediatri Arşivi
https://www.readbyqxmd.com/read/30112012/adverse-childhood-experiences-health-related-quality-of-life-and-chronic-disease-risks-in-rural-areas-of-the-united-states
#2
Amy Chanlongbutra, Gopal K Singh, Curt D Mueller
Exposure to adverse childhood experiences (ACEs) is associated with increased odds of high-risk behaviors and adverse health outcomes. This study examined whether ACE exposure among individuals living in rural areas of the United States is associated with adult activity limitations, self-reported general poor health status, chronic diseases, and poor mental health. Data from the 2011 and 2012 Behavioral Risk Factor Surveillance System (BRFSS) (N=79,810) from nine states were used to calculate the prevalence of ACEs in rural and urban areas...
2018: Journal of Environmental and Public Health
https://www.readbyqxmd.com/read/30104128/implementation-of-the-asthma-control-test-in-primary-care-to-improve-patient-outcomes
#3
Nancy Cantey Banasiak
BACKGROUND: Asthma is one of the major chronic diseases in the pediatric population, affecting 9.5% of children. The National Heart, Lung, and Blood Institute recommends the use of the Asthma Control Test (ACT) for periodic assessment of asthma control. The purpose of this evidence-based project was to implement the Asthma Control Test screening tool into the primary care practice to improve management of patients with asthma by more accurately addressing asthma control. METHODS: The project was a pre- and post-implementation study comparing two different groups of patients with asthma seen at the clinic over 5-week periods...
August 10, 2018: Journal of Pediatric Health Care
https://www.readbyqxmd.com/read/30102428/hospitalisation-in-short-stay-units-for-adults-with-internal-medicine-diseases-and-conditions
#4
REVIEW
Camilla Strøm, Jakob S Stefansson, Maria Louise Fabritius, Lars S Rasmussen, Thomas A Schmidt, Janus C Jakobsen
BACKGROUND: Short-stay units are hospital units that provide short-term care for selected patients. Studies have indicated that short-stay units might reduce admission rates, time of hospital stays, hospital readmissions and expenditure without compromising the quality of care. Short-stay units are often defined by a target patient category, a target function, and a target time frame. Hypothetically, short-stay units could be established as part of any department, but this review focuses on short-stay units that provide care for participants with internal medicine diseases and conditions...
August 13, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/30083639/cor-triatriatum-case-report-of-emergency-department-diagnosis
#5
Camille Halfman, Asalim Thabet, Rebecca Blue, Tyler Greenfield
Cor triatriatum is a rare, congenital heart defect. When diagnosis does not occur in infancy, primary symptoms in an older patient may mimic reactive airway disease. We report a case of cor triatriatum in an older child, previously diagnosed with asthma, presenting to an emergency department with a chief complaint of wheezing. Initial treatment with bronchodilators and corticosteroids was unsuccessful, prompting thorough evaluation. Subsequent imaging diagnosed cor triatriatum sinister. When presentations consistent with common conditions, such as asthma, do not respond appropriately to classic intervention, emergency physicians must be prepared to consider alternative and rare diagnosis...
August 2018: Clinical practice and cases in emergency medicine
https://www.readbyqxmd.com/read/30076281/neutrophil-cytoplasts-induce-t-h-17-differentiation-and-skew-inflammation-toward-neutrophilia-in-severe-asthma
#6
Nandini Krishnamoorthy, David N Douda, Thayse R Brüggemann, Isabell Ricklefs, Melody G Duvall, Raja-Elie E Abdulnour, Kimberly Martinod, Luciana Tavares, Xiao Wang, Manuela Cernadas, Elliot Israel, David T Mauger, Eugene R Bleecker, Mario Castro, Serpil C Erzurum, Benjamin M Gaston, Nizar N Jarjour, Sally Wenzel, Eleanor Dunican, John V Fahy, Daniel Irimia, Denisa D Wagner, Bruce D Levy
Severe asthma is a debilitating and treatment refractory disease. As many as half of these patients have complex neutrophil-predominant lung inflammation that is distinct from milder asthma with type 2 eosinophilic inflammation. New insights into severe asthma pathogenesis are needed. Concomitant exposure of mice to an aeroallergen and endotoxin during sensitization resulted in complex neutrophilic immune responses to allergen alone during later airway challenge. Unlike allergen alone, sensitization with allergen and endotoxin led to NETosis...
August 3, 2018: Science Immunology
https://www.readbyqxmd.com/read/30045724/medications-that-reduce-emergency-hospital-admissions-an-overview-of-systematic-reviews-and-prioritisation-of-treatments
#7
Niklas Bobrovitz, Carl Heneghan, Igho Onakpoya, Benjamin Fletcher, Dylan Collins, Alice Tompson, Joseph Lee, David Nunan, Rebecca Fisher, Brittney Scott, Jack O'Sullivan, Oliver Van Hecke, Brian D Nicholson, Sarah Stevens, Nia Roberts, Kamal R Mahtani
BACKGROUND: Rates of emergency hospitalisations are increasing in many countries, leading to disruption in the quality of care and increases in cost. Therefore, identifying strategies to reduce emergency admission rates is a key priority. There have been large-scale evidence reviews to address this issue; however, there have been no reviews of medication therapies, which have the potential to reduce the use of emergency health-care services. The objectives of this study were to review systematically the evidence to identify medications that affect emergency hospital admissions and prioritise therapies for quality measurement and improvement...
July 26, 2018: BMC Medicine
https://www.readbyqxmd.com/read/30044773/cigarette-and-e-cigarette-dual-use-and-risk-of-cardiopulmonary-symptoms-in-the-health-eheart-study
#8
Julie B Wang, Jeffrey E Olgin, Gregory Nah, Eric Vittinghoff, Janine K Cataldo, Mark J Pletcher, Gregory M Marcus
E-cigarettes are promoted as healthier alternatives to conventional cigarettes. Many cigarette smokers use both products. It is unknown whether the additional use of e-cigarettes among cigarette smokers (dual users) is associated with reduced exposure to tobacco-related health risks. Cross-sectional analysis was performed using baseline data from the Health eHeart Study, among English-speaking adults, mostly from the United States. Cigarette use (# cigarettes/day) and/or e-cigarette use (# days, # cartridges, and # puffs) were compared between cigarette only users vs...
2018: PloS One
https://www.readbyqxmd.com/read/30036600/generating-evidence-to-inform-an-update-of-asthma-clinical-practice-guidelines-perspectives-from-the-national-heart-lung-and-blood-institute
#9
George A Mensah, James P Kiley, Gary H Gibbons
Asthma is the most prevalent chronic respiratory disease worldwide. Its increasing prevalence and evidence of suboptimal control require renewed efforts in the development and widespread implementation of clinical practice guidelines for prevention, treatment, and control. Given the rapidly changing landscape and evolving best practices for guideline development, the National Heart, Lung, and Blood Institute made a commitment to support rigorous systematic evidence reviews that frontline health care providers and stakeholders could use to create new or update existing guidelines...
July 21, 2018: Journal of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/30030316/prevalence-of-potentially-inappropriate-medications-at-admission-and-discharge-among-hospitalised-elderly-patients-with-acute-medical-illness-at-a-single-centre-in-japan-a-retrospective-cross-sectional-study
#10
Junpei Komagamine
OBJECTIVE: To determine the prevalence of potentially inappropriate medications (PIMs) at admission and discharge among hospitalised elderly patients with acute medical illness in Japan. DESIGN: A retrospective single-centre cross-sectional study. PARTICIPANTS: Hospitalised patients aged 65 years or older admitted for pneumonia, heart failure, ischaemic stroke, acute coronary syndrome, chronic obstructive pulmonary disease or asthma, gastrointestinal bleeding, urinary tract infection or epilepsy from September 2014 to June 2016 who were still alive at discharge...
July 19, 2018: BMJ Open
https://www.readbyqxmd.com/read/30019762/improving-nursing-facility-care-through-an-innovative-payment-demonstration-project-optimizing-patient-transfers-impacting-medical-quality-and-improving-symptoms-transforming-institutional-care-phase-2
#11
Kathleen T Unroe, Nicole R Fowler, Jennifer L Carnahan, Laura R Holtz, Susan E Hickman, Shannon Effler, Russell Evans, Kathryn I Frank, Monica L Ott, Greg Sachs
Optimizing Patient Transfers, Impacting Medical Quality, and Improving Symptoms: Transforming Institutional Care (OPTIMISTIC) is a 2-phase Center for Medicare and Medicaid Innovations demonstration project now testing a novel Medicare Part B payment model for nursing facilities and practitioners in 40 Indiana nursing facilities. The new payment codes are intended to promote high-quality care in place for acutely ill long-stay residents. The focus of the initiative is to reduce hospitalizations through the diagnosis and on-site management of 6 common acute clinical conditions (linked to a majority of potentially avoidable hospitalizations of nursing facility residents): pneumonia, urinary tract infection, skin infection, heart failure, chronic obstructive pulmonary disease or asthma, and dehydration...
July 18, 2018: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/30017541/misdiagnosed-coronary-artery-disease-acute-aortic-syndrome-a-case-report
#12
Xiao-Yu Zhou, Jing Xu
It is estimated that 15% of traffic accidents cause trauma to large vessels. In about 70%-95% of cases, aortic rupture took place in the distal ligament of the left subclavian artery, whereas in the remaining cases rupture occurred in the ascending aorta above the aortic valve. Trauma to the aortic sinus and coronary arteries is rarely found in traffic accident victims. Therefore, coronary artery trauma is often misdiagnosed as coronary atherosclerotic heart disease. The present case is a 42 years old male who survived from a traffic accident...
June 28, 2018: Chinese Journal of Traumatology, Zhonghua Chuang Shang za Zhi
https://www.readbyqxmd.com/read/30013784/association-between-physical-health-and-cardiovascular-diseases-effect-modification-by-chronic-conditions
#13
Nazmus Saquib, Robert Brunner, Manisha Desai, Matthew Allison, Lorena Garcia, Marcia L Stefanick
Objectives: This study assessed whether the physical component summary score of the RAND-36 health-related quality-of-life survey was associated with incidence of coronary heart disease, stroke, congestive heart failure, angina, or peripheral arterial disease, and whether baseline chronic conditions modified these associations. Methods: Analysis was limited to 69,155 postmenopausal women (50-79 years) in the Women's Health Initiative Study who had complete data on the RAND-36, the outcomes, and covariates...
2018: SAGE Open Medicine
https://www.readbyqxmd.com/read/29995144/comparison-of-two-inhalational-techniques-for-bronchodilator-administration-in-children-and-adolescents-with-acute-asthma-crisis-a-meta-analysis
#14
Cristian Roncada, Julia Andrade, Luísa Carolina Bischoff, Paulo Márcio Pitrez
OBJECTIVE: To compare the efficacy of pediatric asthma treatment by nebulizer and metered-dose inhaler with the use of a spacer (MDI-spacer) in rescue techniques for asthmatic patients assisted at pediatric emergency units. DATA SOURCES: A systematic review was conducted to identify the most relevant randomized controlled trials comparing the administration of a bronchodilator (β-2 agonist) by two inhalation techniques (nebulization and MDI-spacer) to treat asthma in children at pediatric emergency units...
July 10, 2018: Revista Paulista de Pediatria: Orgão Oficial da Sociedade de Pediatria de São Paulo
https://www.readbyqxmd.com/read/29990356/prevalence-of-chronic-comorbidities-in-dengue-fever-and-west-nile-virus-a-systematic-review-and-meta-analysis
#15
Alaa Badawi, Russanthy Velummailum, Seung Gwan Ryoo, Arrani Senthinathan, Sahar Yaghoubi, Denitsa Vasileva, Emma Ostermeier, Mikayla Plishka, Marcel Soosaipillai, Paul Arora
BACKGROUND: Flavivirus diseases such as dengue fever (DENV), West Nile virus (WNV), Zika and yellow fever represent a substantial global public health concern. Preexisting chronic conditions such as cardiovascular diseases, diabetes, obesity, and asthma were thought to predict risk of progression to severe infections. OBJECTIVE: We aimed to quantify the frequency of chronic comorbidities in flavivirus diseases to provide an estimate for their prevalence in severe and non-severe infections and examine whether chronic diseases contribute to the increased risk of severe viral expression...
2018: PloS One
https://www.readbyqxmd.com/read/29990113/nocturnal-heart-rate-variability-spectrum-characterization-in-preschool-children-with-asthmatic-symptoms
#16
Javier Milagro, Eduardo Gil, Jesus Lazaro, Ville-Pekka Seppae, Leo Pekka Malmberg, Anna Susanna Pelkonen, Anne Kotaniemi-Syrjanen, Mika Makela, Jari Viik, Raquel Bailon
Asthma is a chronic lung disease that usually develops during chilhood. Despite that symptoms can almost be controlled with medication, early diagnosis is desirable in order to reduce permanent airway obstruction risk. It has been suggested that abnormal parasympathetic nervous system (PSNS) activity might be closely related with the pathogenesis of asthma, and that this PSNS activity could be reflected in cardiac vagal control. In this work, an index to measure the spectral regularity of the high frequency (HF) component of heart rate variability (HRV) spectrum, named peakness (P), is proposed...
November 17, 2017: IEEE Journal of Biomedical and Health Informatics
https://www.readbyqxmd.com/read/29984116/hypertension-and-its-correlates-in-the-oldest-old-population-aged-80-years-and-above-in-urban-south-india
#17
Bana Manishaa Reddy, Enakshi Ganguly, Pawan Kumar Sharma
Background: Hypertension is a major problem among the geriatric population, presenting the risk of multiple associated co-morbidities and organ system damage. Data related to the epidemiology of controlled and uncontrolled hypertension among the oldest old population is sparse, more so from developing countries. The objectives of the present paper were to identify the prevalence and correlates of hypertension according to gender among the urban community-dwelling healthy oldest old population...
2018: Journal of Gerontology & Geriatric Research
https://www.readbyqxmd.com/read/29982151/the-health-benefits-of-the-great-outdoors-a-systematic-review-and-meta-analysis-of-greenspace-exposure-and-health-outcomes
#18
Caoimhe Twohig-Bennett, Andy Jones
BACKGROUND: The health benefits of greenspaces have demanded the attention of policymakers since the 1800s. Although much evidence suggests greenspace exposure is beneficial for health, there exists no systematic review and meta-analysis to synthesise and quantify the impact of greenspace on a wide range of health outcomes. OBJECTIVE: To quantify evidence of the impact of greenspace on a wide range of health outcomes. METHODS: We searched five online databases and reference lists up to January 2017...
July 5, 2018: Environmental Research
https://www.readbyqxmd.com/read/29981108/carbon-pricing-a-win-win-environmental-and-public-health-policy
#19
Anshula Ambasta, Jonathan J Buonocore
Carbon pricing is an important tool for mitigating climate change. Carbon pricing can have significant health co-benefits. Air pollution from fossil fuels leads to detrimental health effects, including premature mortality, heart attacks, hospitalization from cardiorespiratory conditions, stroke, asthma exacerbations, and absenteeism from school and work, and may also be linked to autism spectrum disorder and Alzheimer's disease. Reduction in fossil fuel combustion through a carbon price can lead to improvements in all these areas of health...
June 28, 2018: Canadian Journal of Public Health. Revue Canadienne de Santé Publique
https://www.readbyqxmd.com/read/29971194/conditions-associated-with-essential-tremor-in-veterans-a-potential-role-for-chronic-stress
#20
Adrian Handforth, Gail A Parker
Background: Increased depression, hearing loss, dementia, alcoholism, and mortality in essential tremor patients remain unexplained. We investigated whether conditions associated with tremor are linked to chronic stress. Methods: The FY2013 Veterans Affairs database was queried for 38 selected dual diagnosis combinations in 5,854,223 veterans aged 21-95 years. Results: Post-traumatic stress disorder, anxiety, and depression were the most common psychiatric diagnoses in tremor patients, with the odds ratio exceeding 2 in all 15-year cohorts...
2018: Tremor and Other Hyperkinetic Movements
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