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https://www.readbyqxmd.com/read/30534440/thulium-laser-enucleation-of-the-prostate-thulep-results-complications-and-risk-factors-in-139-consecutive-cases
#1
Marco Raber, Noor N P Buchholz, Augusto Vercesi, Nashaat A Hendawi, Vincenzo Inneo, Giuseppe Di Paola, Lorenzo Tessa, Ismail M Hassan
Objectives: To report our experience with the emerging technique of thulium laser enucleation of the prostate (ThuLEP) for the treatment for prostate hyperplasia. Patients and methods: Our inclusion criteria were an International Prostate Symptom Score (IPSS) of >15 and a quality-of-life (QoL) score of >3 in patients with confirmed bladder outflow obstruction, no longer responsive to medical therapy, with a significant post-void residual urine volume (PVR; >100 mL), with or without recurrent urinary tract infection and/or acute urinary retention...
December 2018: Arab Journal of Urology
https://www.readbyqxmd.com/read/30533562/urethral-calculi-a-rare-cause-of-acute-urinary-retention-in-women
#2
Mustafa Sungur, Murat Baykam, Selahattin Calışkan, Utku Lokman
Urinary retention is defined as the inability to void; frequently the patient is able to void partially, thus can not completely empty the bladder and diagnosed by increased post-void residual urine (PVR) volumes. It is usually seen in men, but a rare condition in women. The etiological factors may be neurological, anatomical, infectious or pharmacological. It can be encountered after gynecological or incontinence surgery. Urethral calculi associated with acute urinary retention in women is a very rare condition, because of the anatomic structure of female urethra...
December 2018: Turkish Journal of Emergency Medicine
https://www.readbyqxmd.com/read/30524621/complications-and-their-treatment-after-midurethral-tape-implantation-using-retropubic-and-transobturator-approaches-for-treatment-of-female-stress-urinary-incontinence
#3
Marija Barisiene, Ausra Cerniauskiene, Augustinas Matulevicius
Introduction: Midurethral tape implantation procedures currently are the first-line treatment for female stress urinary incontinence (SUI). Aim: To estimate the most common intraoperative and postoperative complications and their treatment methods after midurethral tape implantation using retropubic (tension-free vaginal tape - TVT) and transobturator (TOT) approaches for the treatment of female SUI. Material and methods: A retrospective descriptive study was performed on 367 women operated on due to SUI in the period from 2004 to 2015...
December 2018: Wideochirurgia i Inne Techniki Mało Inwazyjne, Videosurgery and Other Miniinvasive Techniques
https://www.readbyqxmd.com/read/30523608/silodosin-an-update-on-efficacy-safety-and-clinical-indications-in-urology
#4
REVIEW
Luca Villa, Paolo Capogrosso, Umberto Capitanio, Alberto Martini, Alberto Briganti, Andrea Salonia, Francesco Montorsi
INTRODUCTION: Silodosin determines smooth muscle relaxation in bladder and prostate tissues, increases bladder blood flow in conditions of chronic bladder ischemia and regulates the activity of transcriptional factors responsible for stromal growth and prostate hyperplasia. Phase III trials have already demonstrated the efficacy and safety of silodosin in the treatment of patients bothered by lower urinary tract symptoms (LUTS) secondary to benign prostatic hyperplasia (BPH). OBJECTIVE: We aimed to describe the rationality for the use of silodosin and to summarize the current literature on the use of Silodosin for the treatment of LUTS...
December 6, 2018: Advances in Therapy
https://www.readbyqxmd.com/read/30523028/identification-of-specific-micrornas-in-neutrophils-of-type-2-diabetic-mice-overexpression-of-microrna-129-2-3p-accelerates-diabetic-wound-healing
#5
Takahiro Umehara, Ryoichi Mori, Kimberly A Mace, Takehiko Murase, Yuki Abe, Takuma Yamamoto, Kazuya Ikematsu
Neutrophils are involved in the first stage of acute inflammation. Following injury, they are mobilized and recruited to the injured tissue. In diabetes, wound healing is delayed and aberrant, leading to excessive recruitment and retention of neutrophils that fail to promote angiogenesis and prolong inflammation. However, the exact pathological mechanisms of diabetic-derived neutrophils in chronic inflammation remain unclear. Here, microRNA (miRNA) profiling of neutrophils from bone marrow in type 2 diabetic mice was performed using a microarray...
December 6, 2018: Diabetes
https://www.readbyqxmd.com/read/30522769/platelet-retention-in-inflamed-glomeruli-occurs-via-selective-prolongation-of-interactions-with-immune-cells
#6
Michaela Finsterbusch, M Ursula Norman, Pam Hall, A Richard Kitching, Michael J Hickey
Platelet-leukocyte interactions promote acute glomerulonephritis. However, neither the nature of the interactions between platelets and immune cells nor the capacity of platelets to promote leukocyte activation has been characterized in this condition. We used confocal intravital microscopy to define the interactions of platelets with neutrophils, monocytes, and endothelial cells in glomerular capillaries in mice. In the absence of inflammation, platelets underwent rapid on/off interactions with immune cells...
November 29, 2018: Kidney International
https://www.readbyqxmd.com/read/30511357/acute-urinary-retention-in-two-adolescent-girls-with-imperforate-hymen
#7
Kenji Goto
Acute urinary retention is rare symptom in young adolescent girls. Imperforate hymen can be a cause of acute urinary retention possibly due to the pressure effect of the distended vagina (hematocolpos) on the lower urinary tract. However, the mechanism of progression to urinary retention is unknown. We report on two cases of adolescent girls with imperforate hymen who presented with acute urinary retention. A series of volume tolerance tests of the urinary bladder and urodynamic studies before operation revealed highly elevated urethral resistance, which was induced by interaction of large amount of urinary volume in the bladder and the large size of hematocolpos...
December 3, 2018: Journal of Obstetrics and Gynaecology Research
https://www.readbyqxmd.com/read/30505932/comparison-of-early-and-delayed-eus-guided-drainage-of-pancreatic-fluid-collection
#8
Tanyaporn Chantarojanasiri, Natsuyo Yamamoto, Yousuke Nakai, Tomotaka Saito, Kei Saito, Ryunosuke Hakuta, Kazunaga Ishigaki, Tsuyoshi Takeda, Rie Uchino, Naminatsu Takahara, Suguru Mizuno, Hirofumi Kogure, Saburo Matsubara, Minoru Tada, Hiroyuki Isayama, Kazuhiko Koike
Background and study aims  While endoscopic ultrasound (EUS)-guided drainage of pancreatic fluid collection (PFC) is recommended to be performed ≥ 4 weeks after onset of acute pancreatitis (AP), early (< 4 weeks) interventions are needed in some symptomatic cases. Despite feasibility of early percutaneous drainage, there have been few studies about early EUS-guided drainage of PFC. Patients and methods  Consecutive patients who received EUS-guided drainage (EUS-PCD) of infected or symptomatic PFC at the University of Tokyo were retrospectively studied...
December 2018: Endoscopy International Open
https://www.readbyqxmd.com/read/30505819/comparison-of-the-delta-neutrophil-index-with-procalcitonin-erythrocyte-sedimentation-rate-and-c-reactive-protein-as-predictors-of-sepsis-in-patients-with-acute-prostatitis
#9
Hyun Kyu Ahn, Kyo Chul Koo, Byung Ha Chung, Kwang Suk Lee
Background: We investigated the usefulness of inflammatory markers including the delta neutrophil index (DNI), erythrocyte sedimentation rate, C-reactive protein, and procalcitonin as early predictors of sepsis in patients with acute prostatitis (AP). In addition, we evaluated the efficacy of intermittent catheterization for the initial management of acute urinary retention (AUR) in patients with AP. Materials and methods: All patients who presented to the emergency department and were admitted to the urology department from January 2011 to December 2013 were retrospectively reviewed...
December 2018: Prostate International
https://www.readbyqxmd.com/read/30498778/cardiac-cell-integrated-microneedle-patch-for-treating-myocardial-infarction
#10
Junnan Tang, Jinqiang Wang, Ke Huang, Yanqi Ye, Teng Su, Li Qiao, Michael Taylor Hensley, Thomas George Caranasos, Jinying Zhang, Zhen Gu, Ke Cheng
We engineered a microneedle patch integrated with cardiac stromal cells (MN-CSCs) for therapeutic heart regeneration after acute myocardial infarction (MI). To perform cell-based heart regeneration, cells are currently delivered to the heart via direct muscle injection, intravascular infusion, or transplantation of epicardial patches. The first two approaches suffer from poor cell retention, while epicardial patches integrate slowly with host myocardium. Here, we used polymeric MNs to create "channels" between host myocardium and therapeutic CSCs...
November 2018: Science Advances
https://www.readbyqxmd.com/read/30489383/ustur-case-0846-modeling-americium-biokinetics-after-intensive-decorporation-therapy
#11
Bastian Breustedt, Maia Avtandilashvili, Stacey L McComish, Sergei Y Tolmachev
Decorporation therapy with salts of diethylenetriamine-pentaacetic acid binds actinides, thereby limiting uptake to organs and enhancing the rate at which actinides are excreted in urine. International Commission on Radiological Protection reference biokinetic models cannot be used to fit this enhanced exertion simultaneously with the baseline actinide excretion rate that is observed prior to the start of therapy and/or after the effects of therapy have ceased. In this study, the Coordinated Network on Radiation Dosimetry approach, which was initially developed for modeling decorporation of plutonium, was applied to model decorporation of americium using data from a former radiation worker who agreed to donate his body to the US Transuranium and Uranium Registries for research...
November 27, 2018: Health Physics
https://www.readbyqxmd.com/read/30489370/modeling-the-optimum-prussian-blue-treatment-for-acute-radiation-syndrome-following-137cs-ingestion
#12
Tim G Adams, Rocco Casagrande
Accidents or radiological attacks may lead to ingestion of Cs by large numbers of the public. This work models the efficacy of Prussian blue, the medical countermeasure for internal contamination with Cs, to prevent acute radiation syndrome as a function of the duration of treatment and the time that treatment starts after uptake. Risk of acute radiation syndrome is modeled using the International Commission on Radiological Protection's acute radiation hazard model. Dose rates to target organs from Cs ingestion were based on the data published by the US Environmental Protection Agency and the retention of Cs in the reference man...
January 2019: Health Physics
https://www.readbyqxmd.com/read/30488856/does-it-matter-if-it-is-appendix-mucocele-instead-of-appendicitis-case-series-and-brief-review-of-literature
#13
Fatih Basak, Mustafa Hasbahceci, Metin Yucel, Abdullah Sisik, Aylin Acar, Ali Kilic, Meliha Seyma Su Dur
Aims: Appendiceal mucocele (AM) is a rare pathology, and its reported incidence is 0.3% in all appendectomy specimens. Here, we report a case series of AM and make a brief review of literature. Subjects and Methods: We conducted a retrospective review of a prospectively collected data of patients who diagnosed as AM by histopathological evaluation between January 2009 and June 2015 were demographic data including age and gender, intraoperative findings, and histopathological reports were recorded...
October 2018: Journal of Cancer Research and Therapeutics
https://www.readbyqxmd.com/read/30487117/effect-of-a-multimedia-patient-decision-aid-to-supplement-the-informed-consent-process-of-a-peripherally-inserted-central-venous-catheter-procedure-pre-post-quasi-experimental-study
#14
Azizeh K Sowan, Arlienita R Beraya, Adrian Carrola, Charles Reed
BACKGROUND: Informed consent is a complex process to help patients engage in care processes and reach the best treatment decisions. There are many limitations to the conventional consent process that is based on oral discussion of information related to treatment procedures by the health care provider. A conclusive body of research supports the effectiveness of multimedia patient decision aids (PtDAs) in the consent process in terms of patient satisfaction, increased knowledge about the procedure, reduced anxiety level, and higher engagement in the decision making...
November 28, 2018: JMIR Medical Informatics
https://www.readbyqxmd.com/read/30478160/sudden-onset-of-lower-limb-flaccid-paralysis
#15
Francesca Seregni, Saraswathy Sabanathan, Justin Cross, Manali Chitre, Deepa Krishnakumar
A previously well 15-year-old boy presented to the emergency department with sudden-onset severe back pain and inability to weight bear. Preceding this event, he stretched out in bed and felt a click in his back.On examination, he was alert and interactive with normal vital signs. Neurological examination of the lower limbs demonstrated bilateral hypotonia and reduced power to 2/5 proximally and distally, absent reflexes, sensory level at L2 with paraesthesia (pins and needles) and dysaesthesia bilaterally...
November 26, 2018: Archives of Disease in Childhood. Education and Practice Edition
https://www.readbyqxmd.com/read/30476657/rapid-progression-of-metastatic-pan-spinal-epidural-non-small-cell-lung-cancer-following-discontinuation-of-alectinib
#16
Carole S L Spake, Daniel B C Reid, Alan H Daniels
BACKGROUND: Rapid progression of metastatic non-small cell lung cancer (NSCLC) following discontinuation of tyrosine kinase inhibitors (TKI) or anaplastic lymphoma kinase (ALK) inhibitors has been described and is associated with a poor prognosis. We describe the first reported case of accelerated NSCLC tumor extension throughout the entire spinal epidural space. CASE DESCRIPTION: A 68-year-old woman with stage IV ALK-positive metastatic NSCLC presented with acute neck pain, urinary retention, and lower extremity weakness 15 days following discontinuation of alectinib...
November 23, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/30473987/chronic-urinary-retention-due-to-fowler-s-syndrome
#17
Jan Trachta, Johann Wachter, Jan Kriz
Fowler's syndrome (FS) is a rare cause of chronic urinary retention in teenage girls and young women. We present a case of a 14-year-old girl who presented at our hospital 2 weeks after uncomplicated laparoscopic appendectomy. The girl complained of reduced urinary frequency and prolonged micturition time. Following an acute cystitis 2 months later, she completely lost her ability to void. A comprehensive set of investigations to assess the cause of her urinary retention including a cerebral and spinal magnetic resonance imaging (MRI), and videourodynamics were performed...
January 2018: European Journal of Pediatric Surgery Reports
https://www.readbyqxmd.com/read/30460498/a-case-of-fulminant-type-1-diabetes-with-gastric-and-urinary-retention
#18
Chuan Xing, Wenqian Zhao, Yanjun Wang
Fulminant type 1 diabetes (fT1D) is a severe subtype of type 1 diabetes which progresses rapidly with islet cells destroyed almost completely within a short period of time. It is often characterized by flu-like or gastrointestinal symptoms at the onset with negative islet-associated autoantibodies, resulting in an absolute deficiency of endogenous insulin secretion. Poor prognosis can be caused by the significantly higher incidence of metabolic disorders (such as severe ion disorders and elevated serum pancreatic enzymes), acute and chronic complications if not diagnosed and treated in a timely manner...
November 20, 2018: Diabetes Therapy: Research, Treatment and Education of Diabetes and related Disorders
https://www.readbyqxmd.com/read/30456594/the-role-of-osteopontin-in-kidney-diseases
#19
REVIEW
Beata Kaleta
BACKGROUND: Osteopontin (OPN) is a pleiotropic glycoprotein expressed in various cell types in animals and in humans, including bone, immune, smooth muscle, epithelial and endothelial cells. Moreover, OPN is found in kidneys (in the thick ascending limbs of the loop of Henle and in distal nephrons) and urine. The protein plays an important role in mineralization and bone resorption. In addition, OPN is involved in the regulation of immunity and inflammation, angiogenesis and apoptosis...
November 19, 2018: Inflammation Research: Official Journal of the European Histamine Research Society ... [et Al.]
https://www.readbyqxmd.com/read/30453864/time-dependent-effect-of-oligomeric-amyloid-%C3%AE-1-42-induced-hippocampal-neurodegeneration-in-rat-model-of-alzheimer-s-disease
#20
Chennakesavan Karthick, Saravanan Nithiyanandan, Musthafa Mohamed Essa, Gilles J Guillemin, Swaminathan K Jayachandran, Muthuswamy Anusuyadevi
OBJECTIVE: Alzheimer's disease (AD) is characterized with an abnormal deposition of insoluble amyloid-beta (Aβ) peptide plaques, tangles formation and synaptic dysfunction. These result in impaired functioning of neuronal circuits and alter the behavioral response owing to activation of neurotransmitter receptors. Recently, it has been implicated that Aβ influences N-methyl d-aspartate (NMDA) receptor activation in AD; however, the molecular mechanism underlying remains unclear. Thus, emerged specific aim to study the time-course effect of oligomeric Aβ(1-42)  (oAβ1-42 ) on the mRNA expression of genes encoding NMDA and acetylcholine receptors in the rat model of AD...
November 19, 2018: Neurological Research
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