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https://www.readbyqxmd.com/read/30094023/hyponatremia-in-kidney-transplant-patients-its-pathophysiologic-mechanisms
#1
Carlos G Musso, Alejandrina Castañeda, María Giordani, Cesar Mombelli, Silvia Groppa, Nora Imperiali, Guillermo Rosa Diez
Kidney transplant patients (KTPs), and particularly those with advanced chronic kidney rejection, may be affected by opportunistic infections, metabolic alterations and vascular and oncologic diseases that promote clinical conditions that require a variety of treatments, the combinations of which may predispose them to hyponatremia. Salt and water imbalance can induce abnormalities in volemia and/or serum sodium depending on the nature of this alteration (increase or decrease), its absolute magnitude (mild or severe) and its relative magnitude (body sodium:water ratio)...
August 2018: Clinical Kidney Journal
https://www.readbyqxmd.com/read/30092305/clinical-outcome-and-risk-factors-for-failure-in-late-acute-prosthetic-joint-infections-treated-with-debridement-and-implant-retention
#2
Marjan Wouthuyzen-Bakker, Marine Sebillotte, Jose Lomas, Adrian Taylor, Eva Benavent Palomares, Oscar Murillo, Javad Parvizi, Noam Shohat, Javier Cobo Reinoso, Rosa Escudero Sánchez, Marta Fernandez-Sampedro, Eric Senneville, Kaisa Huotari, José Maria Barbero Allende, Joaquín Garcia-Cañete, Jaime Lora-Tamayo, Matteo Carlo Ferrari, Danguole Vaznaisiene, Erlangga Yusuf, Craig Aboltins, Rihard Trebse, Mauro José Salles, Natividad Benito, Andrea Vila, Maria Dolores Del Toro, Tobias Siegfried Kramer, Sabine Petersdorf, Vicens Diaz-Brito, Zeliha Kocak Tufan, Marisa Sanchez, Cédric Arvieux, Alex Soriano
OBJECTIVES: Debridement, antibiotics and implant retention (DAIR) is the recommended treatment for all acute prosthetic joint infections (PJI), but its efficacy in patients with late acute (LA) PJI is not well described. METHODS: Patients diagnosed with LA PJI between 2005 and 2015 were retrospectively evaluated. LA PJI was defined as the development of acute symptoms (≤ 3 weeks) occurring ≥ 3 months after arthroplasty. Failure was defined as: i) the need for implant removal, ii) infection related death, iii) the need for suppressive antibiotic therapy and/or iv) relapse or reinfection during follow-up...
August 6, 2018: Journal of Infection
https://www.readbyqxmd.com/read/30083889/should-we-expand-the-indications-for-the-dair-debridement-antibiotic-therapy-and-implant-retention-procedure-for-staphylococcus-aureus-prosthetic-joint-infections-a-multicenter-retrospective-study
#3
O Lesens, T Ferry, E Forestier, E Botelho-Nevers, P Pavese, E Piet, B Pereira, E Montbarbon, B Boyer, S Lustig, S Descamps
To evaluate factors associated with failure in patients treated with DAIR (debridement, antibiotic therapy, and implant retention) for Staphylococcus aureus prosthetic joint infections (PJIs). We retrospectively analyzed consecutive patients with stable PJI due to S. aureus treated with DAIR at six hospitals between 2010 and 2014. Cox proportional hazards regression was used to study factors associated with treatment failure at 2 years. Of 154 eligible patients, 137 were included (mean age 73 ± 13 years; male 56%)...
August 7, 2018: European Journal of Clinical Microbiology & Infectious Diseases
https://www.readbyqxmd.com/read/30082544/clinicoepidemiological-profiles-clinical-practices-and-the-impact-of-holistic-care-interventions-on-outcomes-of-pediatric-hematolymphoid-malignancies-a-7-year-audit-of-the-pediatric-hematolymphoid-disease-management-group-at-tata-memorial-hospital
#4
Gaurav Narula, Maya Prasad, Shalini Jatia, Papagudi G Subramanian, Nikhil Patkar, Prashant Tembhare, Dhanlaxmi Shetty, Nehal Khanna, Siddharth Laskar, Tanuja Shet, Sridhar Epari, Seema Kembhavi, Sneha Shah, Sajid Qureshi, Sumeet Gujral, Shripad D Banavali
INTRODUCTION: The Pediatric Hematolymphoid Disease Management Group (PHL-DMG) at a tertiary cancer care hospital developed extensive patient support programs to improve retention and outcomes while focusing on protocols adapted to meet patient needs. An audit of measures and outcomes was done for a 7-year period from January 2010 to December 2016. MATERIALS AND METHODS: DMG protocols and patient support activities over the study period were documented and audited...
October 2017: Indian Journal of Cancer
https://www.readbyqxmd.com/read/30079573/the-acute-aphasia-implementation-study-aaims-a-pilot-cluster-randomized-controlled-trial
#5
Kirstine Shrubsole, Linda Worrall, Emma Power, Denise A O'Connor
BACKGROUND: Effective implementation strategies to improve speech and language therapists' (SLTs) aphasia management practices are needed. Australian SLTs working in the acute setting have reported inconsistent implementation of post-stroke aphasia guideline recommendations. Therefore, implementation efforts to address these gaps are necessary. However, little is known about the effectiveness of behaviour-change strategies in SLTs providing acute aphasia management. AIMS: This study designed and tested the feasibility, acceptability and potential effectiveness of a tailored implementation strategy to improve acute SLTs' uptake of evidence in two areas of practice: aphasia-friendly information provision; and collaborative goal setting...
August 5, 2018: International Journal of Language & Communication Disorders
https://www.readbyqxmd.com/read/30077005/vaginal-hysterectomy-with-salpingectomy-for-essure-insert-removal
#6
Axelle Charavil, Aubert Agostini, Caroline Rambeaud, Andy Schmitt, Claire Tourette, Patrice Crochet
STUDY OBJECTIVE: To evaluate the feasibility of an en block salpingectomy at the time of vaginal hysterectomy for removal of Essure inserts. DESIGN: Prospective observational study (Canadian Task Force Classification II1) SETTING: Monocenter study at the Conception University Hospital Center, Marseille, France. PATIENTS: Women seeking removal of the Essure device and candidate for vaginal hysterectomy, from the 1st of January 2017 to the 31st of January 2018...
August 1, 2018: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/30076876/targeting-ability-of-self-assembled-nanomedicines-in-rat-acute-limb-ischemia-model-is-affected-by-size
#7
Masamitsu Suhara, Yutaka Miura, Horacio Cabral, Daisuke Akagi, Yasutaka Anraku, Akihiro Kishimura, Masaya Sano, Takuya Miyazaki, Noriko Nakamura, Ayako Nishiyama, Kazunori Kataoka, Hiroyuki Koyama, Katsuyuki Hoshina
Peripheral artery disease (PAD) is one of the most spreading diseases all over the world. The treatment strategies are limited to surgical or endovascular procedures for final stage chronic PAD or acute limb ischemia, and no pharmacological approaches have been achieved to prevent the worsening of chronic PAD or to regenerate the tissues of acute limb ischemia. Therefore, the improvement of therapeutic strategy is strongly demanded in clinics. Here, we adopted an acute hindlimb ischemia model in rats, which provides concomitant inflammatory response, to evaluate the application of drug delivery system against PAD...
August 1, 2018: Journal of Controlled Release: Official Journal of the Controlled Release Society
https://www.readbyqxmd.com/read/30076494/neurogenic-lower-urinary-tract-dysfunction-in-multiple-sclerosis-neuromyelitis-optica-and-related-disorders
#8
REVIEW
Ryuji Sakakibara
PURPOSE: Multiple sclerosis (MS), neuromyelitis optica (NMO), and related disorders are major immune-mediated central nervous system diseases affecting the spinal cord. We reviewed the occurrence of neurogenic lower urinary tract dysfunction (NLUTD) in these categories of diseases. METHODS: We systematically reviewed the literature regarding bladder dysfunction in MS, NMO spectrum disorder (NMOSD), and related disorders (acute disseminated encephalomyelitis, acute immune-mediated myelopathy, and meningitis-retention syndrome)...
August 3, 2018: Clinical Autonomic Research: Official Journal of the Clinical Autonomic Research Society
https://www.readbyqxmd.com/read/30072555/a-case-of-guillain-barr%C3%A3-syndrome-gbs-presenting-with-acute-urinary-retention-and-t6-sensory-level
#9
Ching Soong Khoo, Alyaa Hassan Ali, Rabani Remli, Hui Jan Tan
Guillain-Barré syndrome (GBS) is an acute immune-mediated demyelinating disease. Early recognition of this disease is crucial as it can progress to life-threatening conditions such as respiratory failure or autonomic dysfunction. Typical clinical manifestations of GBS include progressive weakness of the limbs, bulbar, facial muscles and ophthalmoplegia. Sensory level and bladder dysfunction are more suggestive of acute myelopathy. We report a case of GBS presenting with acute urinary retention and T6 sensory level, which was successfully treated with plasma exchange...
August 2018: Clinical Medicine: Journal of the Royal College of Physicians of London
https://www.readbyqxmd.com/read/30064869/spontaneous-spinal-subarachnoid-hemorrhage-presentation-and-outcome
#10
Micah D Yost, Alejandro A Rabinstein
BACKGROUND: Spontaneous spinal subarachnoid hemorrhage (SSAH) is a rare but serious condition that can lead to a variety of medical complications. METHODS: Using the Mayo Clinic Rochester database, consecutive patients admitted to the Mayo Clinic Rochester, Minnesota hospital with spontaneous SSAH (not iatrogenic or traumatic) between January 2000 and December 2015 were retrospectively reviewed. Demographic and clinical data and functional outcomes as categorized by the modified Rankin Scale (mRS) score at the time of discharge and at postadmission follow-up were assessed...
July 28, 2018: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/30059879/assessment-of-ethylene-glycol-diacetate-as-an-alternative-carrier-for-use-in-agrochemical-emulsifiable-concentrate-formulation
#11
Xian-Peng Zhang, Tong-Fang Jing, Da-Xia Zhang, Jian Luo, Bei-Xing Li, Feng Liu
The conventional emulsifiable concentrate (EC) formulation contains a large amount of aromatic solvents, which causes adverse effects to both the environment and human health due to the toxicity of the solvents. Here, we developed a 2.5% lambda-cyhalothrin EC formulation with ethylene glycol diacetate (EGDA) as the solvent, and the developed formulation serves as an environmental-friendly alternative to overcome the adverse effects of aromatic solvents. The physicochemical characterizations, wettability properties, phytotoxicity and bioassays of the EGDA-EC formulation were systematically investigated and compared with that of the EC formulation with xylene as the solvent...
July 27, 2018: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/30057014/methoxyflurane-for-procedural-analgesia-at-4470-m-altitude
#12
Matt Wilkes, Eleanor C Heath, Nicholas P Mason
Methoxyflurane is a volatile, fluorinated anesthetic agent with analgesic properties. Although no longer used as an anesthetic due to concerns regarding renal toxicity in high doses, it has enjoyed a resurgence as an inhaled analgesic in prehospital care and in the emergency department. The agent is nonflammable and leads to rapid, titratable analgesia without intravenous access. The Penthrox inhaler device is light, robust, and straightforward to administer. Consequently, it has been proposed as an ideal analgesic for the remote high altitude setting...
July 26, 2018: Wilderness & Environmental Medicine
https://www.readbyqxmd.com/read/30055485/brewery-wastewater-treatment-and-resource-recovery-through-long-term-continuous-mode-operation-in-pilot-photosynthetic-bacteria-membrane-bioreactor
#13
Haifeng Lu, Meng Peng, Guangming Zhang, Baoming Li, Yuanyuan Li
Photosynthetic bacteria (PSB) are considered ideal for high COD wastewater treatment and resource recovery. This work is the first continuous-mode long-term (440 days) pilot study (240 L) by using PSB-membrane (PSB-MBR) system for such purpose. Results showed that the system started-up in 27 days for brewery wastewater and then stably operated under various temperature, initial COD and pH conditions, which showed fast start-up and strong robustness. Comparing with small-batch PSB-MBR system, the capacity of pollutants treatment degradation rate in the pilot-continuous PSB-MBR system was promoted...
July 20, 2018: Science of the Total Environment
https://www.readbyqxmd.com/read/30047278/integrated-care-on-leaving-hospital-against-medical-advice-among-hiv-infected-people-with-substance-use-disorders
#14
Gabriel Vallecillo, Maria Jose Robles, Francina Fonseca, Claudio Tamarit, Xavier Duran, Alexandra Garcia-Guix, Marta Torrens
OBJECTIVES: HIV-infected people with substance use disorders (HIV-SUD) are at increased risk of leaving hospital against medical advice (LHAMA). The aim of this study was evaluate the incidence of LHAMA in HIV-SUD admitted to a patient-centered hospital where they receive integrated care, including health care, substance use treatment, and social support. METHODS: observational study at an urban acute-care university teaching hospital. Integrated care included a specialist in addiction medicine and a social worker incorporated into the medical staff...
July 26, 2018: AIDS Research and Human Retroviruses
https://www.readbyqxmd.com/read/30046505/adult-bilateral-ureteroceles-presenting-with-lower-urinary-tract-symptoms-and-acute-urinary-retention
#15
Alexis Rompré-Brodeur, Sero Andonian
Ureterocele is a well-known pathologic entity in the pediatric urology population but remains a diagnostic and treatment challenge in the adult population. Adult ureteroceles remain a diagnostic challenge for the adult urologist. Its prevalence is estimated between 1/500 and 1/4000 patients with a wide variety of clinical presentations. We present the case of a 30-year-old female patient who presented with severe lower urinary tract symptoms (LUTS) and acute urinary retention secondary to prolapsing bilateral single-system orthotopic ureteroceles...
2018: Case Reports in Urology
https://www.readbyqxmd.com/read/30043714/effectiveness-of-the-addition-of-tadalafil-to-tamsulosin-in-the-treatment-of-acute-urinary-retention-in-patients-with-benign-prostatic-hyperplasia-a-randomized-clinical-trial
#16
Hamidreza Baghani Aval, Zeinab Ameli, Mojtaba Ameli
INTRODUCTION: Acute urinary retention is one of the most significant complications of benign prostatic hyperplasia. Until now, standard treatments include catheterization and use of α-blockers. Tadalafil has been recently seen to also play a role in the treatment of urinary symptoms caused by benign prostatic hyperplasia. The aim of this study was to survey the addition of tadalafil to tamsulosin in the treatment of acute urinary retention in patients with benign prostatic hyperplasia...
May 2018: Urologia
https://www.readbyqxmd.com/read/30042106/transabdominal-ultrasound-guided-gartner-s-abscess-drainage-a-rare-cause-of-acute-urinary-retention-in-second-trimester-of-pregnancy
#17
Manju Lata Verma, Vartika Tripathi, Uma Singh, Pushpa Lata Sankhwar
Acute retention of urine in pregnancy is an emergency, since it can lead to loss of pregnancy besides other dire complications. Gartner's abscess is an extremely rare cause for this condition. We present a case of a 23-year-old primigravida woman who presented to us at 24 weeks of pregnancy with acute retention of urine. After clinical and radiological evaluation, a large Gartner's abscess was found to be the cause. Per vaginal drainage of the abscess was not attempted because insertion of transvaginal probe was extremely painful for the patient, and the abscess was located high up in the anterior fornix...
July 24, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/30037868/providing-psychological-support-to-people-in-intensive-care-development-and-feasibility-study-of-a-nurse-led-intervention-to-prevent-acute-stress-and-long-term-morbidity
#18
Dorothy Wade, Nicole Als, Vaughan Bell, Chris Brewin, Donatella D'Antoni, David A Harrison, Mags Harvey, Sheila Harvey, David Howell, Paul R Mouncey, Monty Mythen, Alvin Richards-Belle, Deborah Smyth, John Weinman, John Welch, Chris Whitman, Kathryn M Rowan
OBJECTIVES: Adverse psychological outcomes, following stressful experiences in critical care, affect up to 50% of patients. We aimed to develop and test the feasibility of a psychological intervention to reduce acute stress and prevent future morbidity. DESIGN: A mixed-methods intervention development study, using two stages of the UK Medical Research Council framework for developing and testing complex interventions. Stage one (development) involved identifying an evidence base for the intervention, developing a theoretical understanding of likely processes of change and modelling change processes and outcomes...
July 23, 2018: BMJ Open
https://www.readbyqxmd.com/read/30037602/clinical-features-of-a-fatal-shoulder-dystocia-the-hypovolemic-shock-hypothesis
#19
E Cesari, S Ghirardello, G Brembilla, A Svelato, A Ragusa
Shoulder dystocia is a rare but severe obstetric complication associated with an increased risk of brachial plexus palsies, fractures of the clavicle and humerus, hypoxic-ischemic encephalopathy and, rarely, neonatal death. Here we describe a fatal case of shoulder dystocia in a term newborn, although labor was uneventful, fetal heart rate tracing was normal until the delivery of the head and the head-to-body delivery interval (HBDI) occurred within 5 min. Full resuscitation was performed for 35 min without success...
September 2018: Medical Hypotheses
https://www.readbyqxmd.com/read/30035424/-en-bloc-holmium-laser-enucleation-of-the-prostate-holep-en-bloc-our-experience
#20
L M Rapoport, N I Sorokin, R B Sukhanov, A M Dymov, D V Enikeev, D S Davydov, S P Danilov
INTRODUCTION: Some authors consider HoLEP a new gold standard for the surgical management of prostatic hyperplasia. The increasing utilization of holmium enucleation has led to the development of various modifications of this treatment modality, including the so-called enucleation as a single piece (HoLEP en bloc), which reduces the operative time and, according to some authors, facilitates acquiring new surgical technique by surgical trainees. AIM: To compare the effectiveness and safety of the traditional HoLEP and HoLEP en bloc...
July 2018: Urologii︠a︡
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