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Ingela Thylén, Debra K Moser, Anna Strömberg
BACKGROUND: Elderly individuals are increasingly represented among patients with implantable cardioverter defibrillators (ICD), but data describing life with an ICD are scarse among octo- and nonagenarians. Moreover, few studies have reported those elderly patients' perspective on timly discussions concerning what shock deactivation involves, preferences on battery replacement, and their attitudes about turning off the ICD nearing end-of-life. Consequently, the aim of the study was to describe outlooks on life and death in octo- and nonagenarian ICD-recipients...
October 20, 2018: BMC Geriatrics
Erdem A Sezgin, Otto Robertsson, Annette W-Dahl, Lars Lidgren
Background and purpose - The nonagenarian (those aged 90 years and older) population is expected to double in the next 20 years. This demographic age quake may have a significant impact on the incidence of total knee arthroplasty (TKA), although current literature provides limited data. We examined death and revision rates, patient-reported outcomes (PROs) and bias on patient selection of nonagenarian patients operated on with TKA for osteoarthritis (OA) between 2000 and 2016. Patients and methods - The Swedish national knee arthroplasty register was used to identify 329 nonagenarians (mean age, 92 years)...
October 18, 2018: Acta Orthopaedica
Maarit Venermo
No abstract text is available yet for this article.
October 1, 2018: European Journal of Vascular and Endovascular Surgery
Tetsuji Morishita, Yusuke Sato, Yoshitomo Fukuoka, Kentaro Ishida, Ryotaro Urabe, Ryohei Shigehara, Yoshiki Minegishi, Hiroyasu Uzui, Hiroshi Tada
The number of implantations of cardiac implantable electrophysiological devices (CIEDs) has increased over the past several years. However, the aging population and expansion of indications for CIEDs have led to an increase in associated infections. We experienced a case of a 99-year-old man presenting with skin erosion at the pocket site, where a 6-month-old implantable pacemaker was replaced. He was referred for pacemaker pocket infection and presented with fever accompanied by pain and swelling around pacemaker generator...
August 2018: Journal of Cardiology Cases
Montserrat Barceló, Esther Francia, Carlos Romero, Domingo Ruiz, Jordi Casademont, Olga H Torres
INTRODUCTION: Centenarians and nonagenarians constitute a rapidly growing age group in Western countries and they are expected to be admitted to hospital with hip fractures. The aim of this study was to compare outcomes of centenarian and nonagenarian patients following a hip fracture and to identify risk factors related to in-hospital and post-discharge mortality in both groups. PATIENTS AND METHODS: A prospective evaluation of centenarian patients and nonagenarian controls admitted to a tertiary university hospital in Barcelona with hip fractures over a period of 5 years and 9 months...
September 26, 2018: Injury
Etienne L Couture, Paul Farand, Michel Nguyen, Catherine Allard, George A Wells, Samer Mansour, Stéphane Rinfret, Jonathan Afilalo, Mark Eisenberg, Martine Montigny, Simon Kouz, Marc Afilalo, Claude Lauzon, Jean-Pierre Dery, Philippe L'Allier, Erick Schampaert, Jean-Claude Tardif, Thao Huynh
BACKGROUND: Published data about nonagenarians with acute coronary syndrome (ACS) were mainly descriptive and limited by small sample sizes and unadjusted outcomes. We aim to describe the characteristics, management, and the impact of an invasive strategy on major adverse events in elderly patients hospitalized with ACS with focus on the nonagerians. METHODS AND RESULTS: We analyzed data collected as part of the AMI-OPTIMA study, a cluster-randomized study of knowledge translation intervention versus usual care on optimal discharge medications in patients admitted with ACS at 24 Canadian hospitals...
September 30, 2018: Catheterization and Cardiovascular Interventions
Takehiro Sejima, Shuichi Morizane, Katsuya Hikita, Masashi Honda, Atsushi Takenaka
Backgrounds: Surgical procedures in the elderly are associated with higher perioperative morbidity and mortality rates than in younger patients. This is especially significant because elderly individuals are more likely to be operated on now than in the past because they represent the fastest growing subset of the population in advanced countries. Our cases are three nonagenarian patients with renal malignancy in poor general condition and were effectively treated by laparoscopic surgery. Case Presentation: Case 1 was a 91-year-old male patient with a right renal cell carcinoma of pT1b N0 M0...
2018: Journal of Endourology Case Reports
Ilaria Franco, Nicola de'Angelis, Florence Canoui-Poitrine, Bertrand Le Roy, Lise Courtot, Thibault Voron, Razvan Aprodu, Ephrem Salamé, Nour Bou Saleh, Anne Berger, Mehdi Ouaïssi, Donato Francesco Altomare, Denis Pezet, Didier Mutter, Francesco Brunetti, Riccardo Memeo
BACKGROUND: Laparoscopy for colorectal cancer treatment is widely accepted. However, there is no consensus as to whether or not laparoscopy can be considered the preferred treatment strategy in octogenarian and nonagenarian patients with colon cancer. The aim of this study was to compare operative and postoperative outcomes of laparoscopic right colectomy between oldest-old (≥80 years) and younger (<80 years) patients with colon cancer. METHODS: The study population was sampled from the CLIMHET Study Group cohort...
September 25, 2018: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
Duc Dang, Vincent Galand, Aurélie Loirat, Vincent Auffret, Nathalie Behar, Philippe Mabo, Jean-Claude Daubert, Christophe Leclercq, Raphaël P Martins
BACKGROUND: The rate of pacemaker (PM) implantations is constantly growing. Since life expectancy of the population is projected to increase, a large number of nonagenarian patients will need PM implantation. We aimed at analyzing short and long-term outcomes after PM implantation in nonagenarians. METHODS: Patients aged ≥90 yo referred for PM implantation from 2004 to 2017 were included. The primary clinical endpoint was total mortality. Secondary endpoints included procedure-related and in-hospital complications...
September 24, 2018: Clinical Cardiology
Kashish Goel, Tanush Gupta, Rajiv Gulati, Malcolm R Bell, Dhaval Kolte, Sahil Khera, Deepak L Bhatt, Charanjit S Rihal, David R Holmes
OBJECTIVES: This study sought to assess temporal trends and outcomes of percutaneous coronary intervention (PCI) in nonagenarians. BACKGROUND: With increasing life expectancy, nonagenarians requiring PCI are increasing even though outcomes data are limited. METHODS: The National Inpatient Sample was used to identify all hospitalizations for PCI in patients aged ≥90 years from January 1, 2003, to December 31, 2014. The primary outcome was in-hospital mortality...
September 24, 2018: JACC. Cardiovascular Interventions
Kirill Berezhnoi, Leonid Kokov, Aleksandr Vanyukov, Yongcheol Kim
No abstract text is available yet for this article.
2018: Cardiology Journal
Insa Marie Schmidt, Reinhold Kreutz, Dagmar Dräger, Christine Zwillich, Stefan Hörter, Adelheid Kuhlmey, Paul Gellert
BACKGROUND: Centenarians are considered as models of successful aging and represent a special group of patients. The aim of this study was to analyze heart failure epidemiology and treatment trajectories in centenarians compared to nonagenarians (90-99 years of age) and octogenarians (80-89 years of age) with heart failure and with heart failure and kidney disease combined. METHODS: This cohort study used quarterly structured routine data from 1398 German insurants over 6 years prior to death (398 centenarians were compared with 500 nonagenarians and 500 octogenarians)...
October 2018: Drugs & Aging
Rafel Ramos, Marc Comas-Cufí, Ruth Martí-Lluch, Elisabeth Balló, Anna Ponjoan, Lia Alves-Cabratosa, Jordi Blanch, Jaume Marrugat, Roberto Elosua, María Grau, Marc Elosua-Bayes, Luis García-Ortiz, Maria Garcia-Gil
OBJECTIVE: To assess whether statin treatment is associated with a reduction in atherosclerotic cardiovascular disease (CVD) and mortality in old and very old adults with and without diabetes. DESIGN: Retrospective cohort study. SETTING: Database of the Catalan primary care system (SIDIAP), Spain, 2006-15. PARTICIPANTS: 46 864 people aged 75 years or more without clinically recognised atherosclerotic CVD. Participants were stratified by presence of type 2 diabetes mellitus and as statin non-users or new users...
September 5, 2018: BMJ: British Medical Journal
Sara Sabeti, Zeinah Al-Darsani, Bryce Anthony Mander, Maria M Corrada, Claudia H Kawas
BACKGROUND: Several lines of research support associations between sleep and cognition in older adults. However, there is a paucity of data regarding sleep and cognition in nonagenarians and centenarians. AIMS: The current study examined self-reported sleep quantity and sleep quality in relation to hippocampal volume and cognition in adults aged 90 and older. METHODS: A total of 144 participants of The 90+ Study completed The Medical Outcomes Study sleep questionnaire...
September 3, 2018: Aging Clinical and Experimental Research
Andreas Wieland, Alice O Kamphorst, N Volkan Adsay, Jonathan J Masor, Juan Sarmiento, Tahseen H Nasti, Sam Darko, Daniel C Douek, Yue Xue, Walter J Curran, David H Lawson, Rafi Ahmed
PD-1-targeted therapy has dramatically changed advanced cancer treatment. However, many questions remain, including specificity of T cells activated by PD-1 therapy and how peripheral blood analysis correlates to effects at tumor sites. In this study, we utilized TCR sequencing to dissect the composition of peripheral blood CD8 T cells activated upon therapy, comparing it with tumor-infiltrating lymphocytes. We report on a nonagenarian melanoma patient who showed a prominent increase in peripheral blood Ki-67 + CD8 T cells following brain stereotactic radiation and anti-PD-1 immunotherapy...
November 2018: Cancer Immunology, Immunotherapy: CII
L Kocik, H Geinitz, C Track, M Geier, C Nieder
PURPOSE: Specific information about radiation therapy in nonagenarians is limited. In order to shed more light on the feasibility of radiotherapy in this challenging subgroup, a retrospective study was performed. METHODS: The data of 93 consecutive patients receiving irradiation treatment at the Department of Radiation Oncology, Ordensklinikum Linz Barmherzige Schwestern between June 2005 and December 2016 were analyzed. Patient- and treatment-related factors were extracted from the patient records...
August 30, 2018: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
Eleonora Poggiogalle, Katie E Cherry, L Joseph Su, Sangkyu Kim, Leann Myers, David A Welsh, S Michal Jazwinski, Eric Ravussin
OBJECTIVES: Body composition alterations occur during aging. The purpose of the present analysis was to explore the functional consequences of the overlap of sarcopenia and osteoporosis, and the potential role of insulin-like growth factor 1 (IGF1) in their development in the oldest old. SETTING AND PARTICIPANTS: Eighty-seven nonagenarians from the Louisiana Healthy Aging Study were included. MEASURES: The definition of sarcopenia was based on appendicular lean mass (ALM)...
August 24, 2018: Journal of the American Medical Directors Association
Kevin Roedl, Dominik Jarczak, Sophie Becker, Valentin Fuhrmann, Stefan Kluge, Jakob Müller
BACKGROUND: The number of cardiac arrests (CA) in the group of very elderly patients (≥ 90 years) is expected to increase markedly due to the world`s rapidly ageing population. However, only little is known about long term outcome, CA- and intensive care unit (ICU) characteristics of patient's ≥ 90 years (nonagenarians) suffering from CA. METHODS: This single-center retrospective study included all adult patients ≥ 90 years after CA and return of spontaneous circulation (ROSC) which were treated at our ICU between January 1st 2008 and September 15th 2016...
November 2018: Resuscitation
Eiji Ichimoto, Adam Arnofsky, Michael Wilderman, Richard Goldweit, Joseph De Gregorio
Background: Transcatheter aortic valve replacement (TAVR) has been performed for many elderly patients with severe aortic stenosis (AS). The SAPIEN 3 is one of the latest balloon-expandable prosthesis. This study aimed to investigate the early clinical outcomes after TAVR using the SAPIEN 3 in nonagenarians. Methods: A total of 97 consecutive patients underwent TAVR for severe AS between December 2015 and December 2016. Of these, 85 consecutive patients who underwent TAVR using the SAPIEN 3 were included...
June 2018: Journal of Geriatric Cardiology: JGC
Daniel A Tonetti, Bradley A Gross, Shashvat M Desai, Ashutosh P Jadhav, Brian T Jankowitz, Tudor G Jovin
BACKGROUND: Although elderly patients have generally worse outcomes after acute ischemic stroke, they may derive significant incremental benefit from thrombectomy as compared with medical management. Although several case series for octogenarians have been reported, data for nonagenarians are scarce. METHODS: A prospectively maintained institutional mechanical thrombectomy database was reviewed for nonagenarians who underwent thrombectomy between January 2013 and July 2017...
August 10, 2018: World Neurosurgery
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