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Daniel A Tonetti, Bradley A Gross, Shashvat M Desai, Ashutosh P Jadhav, Brian T Jankowitz, Tudor G Jovin
No abstract text is available yet for this article.
August 10, 2018: World Neurosurgery
Sofía Alejandra González Chávez, Vicente Romero Estarlich, Susana Muñoz Yépez, Francisco Javier Ortiz Alonso, José Antonio Serra Rexach
No abstract text is available yet for this article.
August 7, 2018: Revista Española de Geriatría y Gerontología
Takeshi Oichi, Yasushi Oshima, Hiroki Matsui, Kiyohide Fushimi, Sakae Tanaka, Hideo Yasunaga
STUDY DESIGN: Retrospective cohort study. OBJECTIVE: To compare morbidity and mortality between nonagenarians and other older adult patients who underwent elective spine surgery. SUMMARY OF BACKGROUND DATA: There is a lack of information of the perioperative risks of nonagenarians undergoing spine surgery. METHODS: Data of patients aged ≥65 years who underwent elective spine surgery from July 2010 to March 2013 were extracted from the Diagnosis Procedure Combination database, a nationwide administrative inpatient database in Japan...
August 7, 2018: Spine
Qianhui Yu, Zhisong He, Dmitry Zubkov, Shuyun Huang, Ilia Kurochkin, Xiaode Yang, Tobias Halene, Lothar Willmitzer, Patrick Giavalisco, Schahram Akbarian, Philipp Khaitovich
Lipids are essential to brain functions, yet they remain largely unexplored. Here we investigated the lipidome composition of prefrontal cortex gray matter in 396 cognitively healthy individuals with ages spanning 100 years, as well as 67 adult individuals diagnosed with autism (ASD), schizophrenia (SZ), and Down syndrome (DS). Of the 5024 detected lipids, 95% showed significant age-dependent concentration differences clustering into four temporal stages, and resulting in a gradual increase in membrane fluidity in individuals ranging from newborn to nonagenarian...
August 8, 2018: Molecular Psychiatry
Xiaofan Guo, Robert M Hayward, Eric Vittinghoff, Yamin Liu, Sun Yong Lee, Mark J Pletcher, Byron K Lee
Cardiac devices are increasingly an element of treatment for the elderly, leading to more frequent transvenous lead removal (TLR) procedures in this population. Data on TLR in very elderly patients, especially nonagenarians, is scarce. We used Healthcare Cost and Utilization Project Nationwide Inpatient Sample to identify a total of 36,099 patients ≥70 years who underwent TLR from 2005 to 2012, with outcomes including in-hospital mortality and complications. The in-hospital mortality rate was significantly higher in nonagenarians without device infection (0...
June 2, 2018: American Journal of Cardiology
Gabriele Doblhammer, Alexander Barth
We assessed the prevalence of morbidity in long-lived individuals according to age and age at death and explored the association between dementia and other diseases and surviving to age 90 and 100. Using health claims data from the largest German health insurer from 2004 to 2013, we followed birth cohorts from 1908 to 1913 from age 95 until death or survival to age 100 (n=2,865) and compared them with birth cohorts from 1918 to 1923 and their survival from age 85 to age 90 (n=17,013). We observed their exact date of death and main categories of morbidity based on International Classification of Diseases, Tenth Revision, diagnoses...
July 2, 2018: Journal of the American Geriatrics Society
Kerstin Amadori
No abstract text is available yet for this article.
June 27, 2018: Zeitschrift Für Gerontologie und Geriatrie
Tomasz Tokarek, Zbigniew Siudak, Artur Dziewierz, Tomasz Rakowski, Róża Krycińska, Andżelika Siwiec, Dariusz Dudek
BACKGROUND: Despite an increase in the proportion of nonagenarians in demographic structure, there is still a paucity of data on the utilization and outcome of percutaneous coronary interventions (PCIs) in this population. Also, very old patients are under-represented in randomized clinical trials and their treatment is still an emerging challenge. Thus, we sought to compare patient profiles and periprocedural outcomes of PCI in nonagenarians and patients younger than 90 years. PATIENTS AND METHODS: Data were based on the Polish National Registry of PCI (ORPKI)...
June 15, 2018: Coronary Artery Disease
Wolfgang G Kunz, Myriam G Hunink, Konstantinos Dimitriadis, Thomas Huber, Franziska Dorn, Felix G Meinel, Bastian O Sabel, Ahmed E Othman, Maximilian F Reiser, Birgit Ertl-Wagner, Wieland H Sommer, Kolja M Thierfelder
Purpose To determine the impact of patient age on the cost-effectiveness of endovascular therapy (EVT) in addition to standard care (SC) in large-vessel-occlusion stroke for patients aged 50 to 100 years in the United States. Materials and Methods A decision-analytic Markov model was used to estimate direct and indirect lifetime costs and quality-adjusted life years (QALYs). Age-dependent input parameters were obtained from the literature. Deterministic and probabilistic sensitivity analysis for age at index stroke were used...
August 2018: Radiology
Linda Enroth, Mari Aaltonen, Jani Raitanen, Lily Nosraty, Marja Jylhä
Long-term care (LTC) use increases with ageing due to an age-related increase in disability. Both the levels of disability and social resources vary among socioeconomic groups. The association of socioeconomic status with LTC use is largely unexplored for the oldest old. This study examined how occupational class is associated with LTC use among nonagenarians in the context of universal care coverage. A population-based prospective cohort study with 2862 participants who answered the Vitality 90 + Study surveys in 2001, 2003, 2007, or 2010 in Tampere, Finland, was combined with national register data on LTC use...
June 2018: European Journal of Ageing
Giuseppe Toro, Hugo Bothorel, Mo Saffarini, Laurent Jacquot, Julien Chouteau, Jean-Charles Rollier
PURPOSE: While uncemented THA has proven benefits over cemented THA, the use of uncemented components in the elderly remains controversial. The purpose of this study was to compare functional outcomes and complication rates of uncemented THA in patients aged > 80 to patients aged < 80, and determine factors that independently influence functional outcomes. METHODS: The authors evaluated 411 consecutive uncemented THAs at a follow-up of 3.1 ± 0...
June 2, 2018: European Journal of Orthopaedic Surgery & Traumatology: Orthopédie Traumatologie
Yue-Bin Lv, Simin Liu, Zhao-Xue Yin, Xiang Gao, Virginia Byers Kraus, Chen Mao, Jin-Qiu Yuan, Juan Zhang, Jie-Si Luo, Hua-Shuai Chen, Yi Zeng, Xiao-Ming Shi
OBJECTIVE: Current international and national guidelines for body mass index (BMI) and waist circumference (WC) have been recommended to all adults. However, whether recommendations applied to the oldest old (aged 80+) is poorly known. The study objective was to investigate the relation of BMI and WC with 3-year all-cause mortality among the oldest old. DESIGN, SETTING, AND PARTICIPANTS: A total of 4361 Chinese oldest old (mean age 91.8) participated in this community-based prospective cohort study...
May 25, 2018: Journal of the American Medical Directors Association
Stephanie Au, Nicholas T Ventham, Satheesh Yalamarthi, Natarajan Manimaran
BACKGROUND: Increased life expectancy and improved medical management of co-morbidities has led to an increasing number of nonagenarian patients with colorectal cancer being considered for surgical intervention. This study aims to describe the morbidity and mortality of nonagenarians who had operative and non-operative management for colorectal cancer. MATERIALS AND METHODS: A retrospective study of consecutive colorectal cancer patients from 2010 to 2016 in a district general hospital in Scotland who were 90 years old or above was performed...
July 2018: International Journal of Surgery
K Eredics, K M Bretterbauer, E Comploj, A Friedl, T Gschliesser, S Lenart, S Seklehner, F Wimpissinger, S Madersbacher
INTRODUCTION: To investigate the oncological outcome of nonagenarians with bladder cancer as a substantial rise of bladder cancer in the old-old age group in the upcoming decades is expected, due to demographic changes and the peak incidence around the age of 85yrs. The paucity of data of nonagenarians prompted us to investigate the outcome of such patients. PATIENTS AND METHODS: A retrospective, multicenter study was designed to assess patient demographics, tumor patterns, treatment strategies and outcome in patients equal or older than 90 years treated at participating centers...
May 27, 2018: BJU International
Gonzalo Tapia Rico, Christos Karapetis, Amanda R Townsend, Cynthia Piantadosi, Rob Padbury, Amitesh Roy, Guy Maddern, James Moore, Scott Carruthers, David Roder, Timothy J Price
No abstract text is available yet for this article.
May 18, 2018: Acta Oncologica
G Pagliai, F Sofi, F Vannetti, S Caiani, G Pasquini, R Molino Lova, F Cecchi, S Sorbi, C Macchi
OBJECTIVES: To investigate eating habits and adherence to Mediterranean Diet (MD) in relation to the risk of depression in a cohort of nonagenarians enrolled within the Mugello Study, an epidemiological study aimed at investigating both clinically relevant geriatric items and various health issues, including those related to nutritional status. DESIGN: Cross-sectional study. SETTING: Homes and nursing homes in the Mugello area, Florence, Italy...
2018: Journal of Nutrition, Health & Aging
Qiukui Hao, Yuting Wang, Xiang Ding, Biao Dong, Ming Yang, Birong Dong, Yuquan Wei
Frailty is characterized by a decline in physiological reserve and increased vulnerability. Previous studies have shown that KLOTHO (KL) plays a protective role in several age-related diseases. We hypothesize a probable protective effect of KL on frailty in the elderly population and included a cohort of Chinese nonagenarians and centenarians for our study. This study is part of a cross-sectional study and secondary analysis of the Project of Longevity and Aging in Dujiangyan (PLAD) study, which was conducted in Southwest China...
April 30, 2018: Scientific Reports
Sayuri Suwa, Saori Otani, Mayuko Tsujimura, Kotoko Nogawa, Yoko Shiya
AIM: This study aimed to explore the experiences and thoughts of a nonagenarian-centenarian woman with dementia living alone, through detailed analysis of her unsolicited diary. DATA SOURCE: After receiving consent from Aki (a pseudonym), her family and caregivers, copies of her diaries, hand-written in Japanese, were provided for analysis. METHODS: The content of the diaries was broadly organized into themes and qualitative content analysis carried out for each theme along a sequential timeline...
April 2018: International Journal of Nursing Practice
Hiroko Okinaga, Hideo Yasunaga, Kiyoshi Hasegawa, Kiyohide Fushimi, Norihiro Kokudo
Background: As the population is aging, the indication for hepatocellular carcinoma (HCC) resection in patients aged over 80 years will increase. Japan is facing the most aging society worldwide. We examined the safety of hepatectomy in octogenarians and nonagenarians using large-scale data from the Diagnosis Procedure Combination database, a national administrative database in Japan. Method: We conducted a survey to collect data for all inpatients from 2007 and 2012...
March 2018: Liver Cancer
Rajkumar Doshi, Vaibhav Patel, Priyank Shah
Background: Aortic valve stenosis (AS) is very common in the elderly patients above 80 years. Transcatheter aortic valve replacement (TAVR) in such patients is being increasingly performed. This study sought to assess in-hospital outcome differences between octogenarians and nonagenarians and predictors of mortality in nonagenarians undergoing TAVR with severe AS. Method: The study population was derived from the National Inpatient Sample (NIS) for the years 2012-2014 using ICD-9 CM procedure codes 35...
February 2018: Journal of Geriatric Cardiology: JGC
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