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https://www.readbyqxmd.com/read/30119677/six-month-safety-evaluation-of-robenacoxib-tablets-onsior%C3%A2-in-dogs-after-daily-oral-administrations
#1
Céline E Toutain, Patrick Brossard, Stephen B King, Rainer Helbig
BACKGROUND: Robenacoxib is a non-steroidal anti-inflammatory drug available for canine and feline use for the control of pain and inflammation marketed as Onsior™. The aim of this target animal safety study was to evaluate the 6-month safety profile of oral robenacoxib administration. It was a randomized, negative-controlled, parallel group study. Thirty-two healthy, young, experimentally naïve, purebred Beagle dogs were administered 0 (sham control, Group 1), 2, 6, and 10 mg/kg robenacoxib (corresponding to the upper end of the dosage range [1X, Group 2] and multiples thereof [3X and 5X, Group 3 and 4]), orally once daily for 6 months...
August 17, 2018: BMC Veterinary Research
https://www.readbyqxmd.com/read/30094175/morphological-and-molecular-characterization-of-cystoisospora-sp-from-asian-small-clawed-otters-aonyx-cinereus
#2
Toshihiro Tokiwa, Ai Ohnuki, Rie Kubota, Kenichi Tamukai, Kazunori Ike
In this study, we provide the first description of Cystoisospora infection in Asian small-clawed otters ( Aonyx cinereus ). In July 2017, three juvenile otters recently imported from the Republic of Indonesia showed severe diarrhea and were diagnosed with coccidial infection; two of them eventually died. Fecal examination revealed the presence of numerous oocysts. Sporulated oocysts showed typical Cystoisospora features, measuring 24.6 ± 1.6 (22.0-27.0) × 21.8 ± 1.4 (19.0-25.0) μm, with an oocyst length/width ratio of 1...
December 2018: International Journal for Parasitology. Parasites and Wildlife
https://www.readbyqxmd.com/read/30083096/attractant-or-repellent-behavioral-responses-to-mammalian-blood-odor-and-to-a-blood-odor-component-in-a-mesopredator-the-meerkat-suricata-suricatta
#3
Henrik Pettersson, Mats Amundin, Matthias Laska
It is well-established that the odor of mammalian blood is attractive to top predators such as tigers and wolves and aversive to prey species such as mice and rats. Recent studies have shown that the mammalian blood odor component trans -4,5-epoxy-(E)-2-decenal (TED) elicits corresponding behavioral responses in these two groups of mammals. Here we assess whether a mesopredator, that is, a small-bodied carnivorous mammal that is both predator and prey, is attracted to or repelled by the odor of mammalian blood and TED...
2018: Frontiers in Behavioral Neuroscience
https://www.readbyqxmd.com/read/30066743/feline-heartworm-dirofilaria-immitis-infection-first-case-report-of-serological-diagnosis-in-brazil-confirmed-by-molecular-assay
#4
Barbara B Pereira, Bethânia F Bastos, Lucas Keidel, Daniela Leles, Beatriz Brener
The clinical importance of heartworm infection in cats has indeed increased in recent years. Dirofilaria immitis infection has been reported worldwide in cats and continues to be regularly diagnosed in endemic areas. The diagnosis can be overlooked easily, especially in Brazil, where there is not a specific feline immunodiagnostic test, forcing the veterinarians to use a test made for the canine host. In 2015, a 10-year-old female neutered cat was diagnosed with D. immitis using an antigen serological test, based on imunocromatography and designed for dogs...
July 26, 2018: Anais da Academia Brasileira de Ciências
https://www.readbyqxmd.com/read/30066413/canine-and-feline-cutaneous-screw-worm-myiasis-in-malaysia-clinical-aspects-in-76-cases
#5
Hock Siew Han, Peik Yean Toh, Hock Binn Yoong, Hooi Meng Loh, Lee Lee Tan, Yin Yin Ng
BACKGROUND: Cutaneous screw-worm myiasis in companion animals either due to the New World screw-worm, Cochliomyia hominivorax or the Old World screw-worm, Chrysomya bezziana, has been reported particularly in tropical and subtropical regions of the world. Although treatment of screw-worm myiasis in dogs has been described, few studies have been conducted regarding its clinical and epidemiological aspects in companion animals. OBJECTIVES: To describe clinical and epidemiological aspects of canine and feline screw-worm myiasis...
July 31, 2018: Veterinary Dermatology
https://www.readbyqxmd.com/read/30062728/a-survey-of-stereotactic-radiation-therapy-in-veterinary-medicine
#6
Elizabeth M Dunfield, Michelle M Turek, Kevin A Buhr, Neil C Christensen
Radiotherapy plays an important role in curative and palliative cancer treatment. As a novel radiation delivery technique, stereotactic radiotherapy utilizes three-dimensional-conformal treatment planning, high-precision beam delivery technology, and patient specific position verification to target tumors, often in one to five high-dose fractions. Currently, there is no consensus about best stereotactic radiotherapy practices in veterinary radiotherapy. The objective of this study was to document the breadth of perspectives, techniques, and applications of stereotactic radiotherapy in veterinary medicine...
July 30, 2018: Veterinary Radiology & Ultrasound
https://www.readbyqxmd.com/read/30044843/an-international-multi-centre-cohort-study-of-weight-loss-in-overweight-cats-differences-in-outcome-in-different-geographical-locations
#7
John Flanagan, Thomas Bissot, Marie-Anne Hours, Bernabe Moreno, Alexander J German
INTRODUCTION: Feline obesity is a worldwide concern which has recently been formally classified as a disease by the veterinary community. Management involves invoking controlled weight loss by feeding a purpose-formulated food in restricted quantities and altering physical activity. Most weight loss studies conducted in cats have been undertaken in research cat colonies from single geographic locations. The aim of this multi-centre cohort study was to determine the efficacy of a short-term dietary weight loss intervention in overweight pet cats across a range of geographical locations globally...
2018: PloS One
https://www.readbyqxmd.com/read/30040851/mouse-mammary-tumour-virus-like-env-nucleotide-and-p14-signal-peptide-are-present-in-feline-mammary-carcinomas-but-not-in-neoplastic-or-dysplastic-canine-mammary-lesions
#8
Prospero Civita, Michele Menicagli, Claudia Scopelliti, Francesca Lessi, Francesca Millanta, Sara Borsacchi, Francesca Parisi, Giulia Freer, Mauro Pistello, Chiara Maria Mazzanti, Alessandro Poli
Mouse mammary tumour virus-like (MMTV-like) is suspected to be involved in human breast cancer and it has been hypothesized that companion animals might have a role in viral transmission. The aim of our study was to investigate the presence of MMTV-like nucleotide sequences and viral protein in a larger number of feline (FMCs) and canine mammary carcinomas (CMCs) by nested PCR and immunohistochemistry. Results showed that the presence of MMTV-like env sequence in FMCs was 7% (6/86), while all the CMCs and canine dysplastic lesions scored negative...
2018: PloS One
https://www.readbyqxmd.com/read/30036744/human-associated-microbial-populations-as-evidence-in-forensic-casework
#9
Frederike C A Quaak, Tineke van Duijn, Jerry Hoogenboom, Ate D Kloosterman, Irene Kuiper
In forensic investigations involving human biological traces, cell type identification is often required. Identifying the cell type from which a human STR profile has originated can assist in verifying scenarios. Several techniques have been developed for this purpose, most of which focus on molecular characteristics of human cells. Here we present a microarray method focusing on the microbial populations that are associated with human cell material. A microarray with 863 probes targeting (sets of) species, specific genera, groups of genera or families was designed for this study and evaluated with samples from different body sites: hand, foot, groin, penis, vagina, mouth and faeces...
June 30, 2018: Forensic Science International. Genetics
https://www.readbyqxmd.com/read/30017081/molecular-assessment-of-neospora-caninum-and-toxoplasma-gondii-in-hooded-crows-corvus-cornix-in-tehran-iran
#10
Amir Abdoli, Mohsen Arbabi, Majid Pirestani, Mehran Mirzaghavami, Fatemeh Ghaffarifar, Abdolhossein Dalimi, Javid Sadraei
Neospora caninum and Toxoplasma gondii are two closely related protozoan parasites that have been detected from various species of bird hosts. However, little is known about the prevalence of N. caninum and T. gondii in crows. Hence, we examined the molecular frequency of N. caninum and T. gondii in the brain samples of hooded crows (Corvus cornix) that collected from different public parks of Tehran, Iran by nested-PCR method. We used the primers targeting the Nc5 and GRA6 genes for detection of N. caninum and T...
April 2018: Comparative Immunology, Microbiology and Infectious Diseases
https://www.readbyqxmd.com/read/30009528/sporotrichosis-in-southern-brazil-towards-an-epidemic
#11
Vanice Rodrigues Poester, Antonella Souza Mattei, Isabel Martins Madrid, Juliana Tavora Bertazo Pereira, Gabriel Baracy Klafke, Karine Ortiz Sanchotene, Tchana Martinez Brandolt, Melissa Orzechowski Xavier
Rio Grande do Sul (RS) is the second highest state with respect to sporotrichosis incidence in Brazil, with most cases occurring in the southern region. Given the importance of epidemiologic monitoring in hyperendemic areas, this study evaluated the spatial, geographical and annual sporotrichosis incidence over a period of 7 years in the southern region of RS, as well as the disease evolution over the last two decades. Data were collected from the Mycology Laboratory of the Federal University of Rio Grande (FAMED-FURG) and from the Centre for Zoonosis Control (CZC) of the Prefeitura Municipal of Pelotas city...
July 15, 2018: Zoonoses and Public Health
https://www.readbyqxmd.com/read/29999542/verification-of-the-heska-element-point-of-care-blood-gas-instrument-for-use-with-venous-blood-from-alpacas-and-llamas-with-determination-of-reference-intervals
#12
Lisa C Viesselmann, Ricardo Videla, Bente Flatland
BACKGROUND: The Heska Element POC ("EPOC") is a blood gas instrument intended for use with canine, feline, and equine whole blood; no verification for use with camelid specimens has been reported. OBJECTIVES: Using camelid specimens and commercial quality control materials (QCM), we investigatee EPOC analytical performance and establish EPOC camelid reference intervals (RIs). METHODS: Camelid blood (n = 124) was analyzed using the EPOC (pH, pCO2 , pO2 , HCO3 , base excess, SO2 , sodium, potassium, chloride, ionized calcium, TCO2 , anion gap, HCT, HGB, glucose, lactate, and creatinine); plasma was analyzed using a Roche Cobas c501 (sodium, potassium, chloride, TCO2 , anion gap, glucose, and creatinine)...
July 12, 2018: Veterinary Clinical Pathology
https://www.readbyqxmd.com/read/29977229/diagnostic-aspects-of-veterinary-and-human-aspergillosis
#13
Daniel Elad, Esther Segal
The genus Aspergillus is composed of more than 300 species, a fraction of which are involved in animal or human infections mostly following environmental exposure. Various risk factors (i.e., immunosuppression, tuberculosis) have been recognized for human whereas for veterinary infections, unhygienic management, trauma, anatomical conformation of the skull, or suspected immunological deficiencies have been suggested. In animals, aspergillosis is mostly sporadic but in some circumstance such as infections on poultry farms may involve the whole flock...
2018: Frontiers in Microbiology
https://www.readbyqxmd.com/read/29949938/dna-and-protein-analyses-to-confirm-the-absence-of-cross-contamination-and-support-the-clinical-reliability-of-extensively-hydrolysed-diets-for-adverse-food-reaction-pets
#14
Isabelle Lesponne, Jérôme Naar, Sébastien Planchon, Tommaso Serchi, Mauricio Montano
Adverse food reactions (AFR) are a common cause of skin diseases in cats and dogs. The correct diagnosis and management of AFR relies upon clinical nutrition. The reliability of commercial hypoallergenic diets commonly used in AFR has been questioned because studies have shown the presence of proteins not declared on the label ingredients. It is proposed that extensively hydrolysed protein-based diets constitute a reliable nutritional solution. Royal Canin Anallergenic™ Canine and Feline diets are formulated with very low molecular weight feather protein and purified corn starch...
June 26, 2018: Veterinary Sciences
https://www.readbyqxmd.com/read/29947433/evaluation-of-histogel-and-gelfoam-embedded-bronchoalveolar-lavage-and-transtracheal-wash-fluids-compared-with-cytocentrifuged-and-sediment-smear-preparations
#15
Laura Z Haysom, Tekla M Lee-Fowler, Elizabeth A Spangler
BACKGROUND: Storage and temperature significantly impact bronchoalveolar lavage fluid (BALF) analysis, and shipment of samples to diagnostic laboratories is often necessary. Alternative sample preparation methods could limit storage and temperature effects. OBJECTIVES: This study aimed to determine if airway wash samples that were fixed in formalin after being embedded in Histogel or Gelfoam gave comparable results to fresh cytocentrifuged or sediment smear preparations for the evaluation of cell morphology...
June 27, 2018: Veterinary Clinical Pathology
https://www.readbyqxmd.com/read/29942073/macroevolution-of-gastric-helicobacter-species-unveils-interspecies-admixture-and-time-of-divergence
#16
Annemieke Smet, Koji Yahara, Mirko Rossi, Alfred Tay, Steffen Backert, Ensser Armin, James G Fox, Bram Flahou, Richard Ducatelle, Freddy Haesebrouck, Jukka Corander
Since the discovery of the human pathogen Helicobacter pylori, various other Helicobacter species have been identified in the stomach of domesticated and wild mammals. To better understand the evolutionary history of these ecologically similar but genetically distinct species, we analyzed 108 gastric Helicobacter genomes and included 54 enterohepatic Helicobacter genomes for comparison purposes. An admixture analysis supported the presence of an ecological barrier, preventing the genetic exchange between the gastric and enterohepatic Helicobacter species, and unraveled many gene flow events within and across species residing in the stomach...
June 25, 2018: ISME Journal
https://www.readbyqxmd.com/read/29940943/otitis-in-a-cat-associated-with-corynebacterium-provencense
#17
Sonja Kittl, Isabelle Brodard, Lorenz Rychener, Jörg Jores, Petra Roosje, Stefanie Gobeli Brawand
BACKGROUND: The role of corynebacteria in canine and feline otitis has not been investigated in detail; however, members of this genus are increasingly recognized as pathogens of otitis in both human and veterinary medicine. CASE PRESENTATION: Here we report the first case of feline otitis associated with the recently described species Corynebacterium provencense. A seven-month old cat presented with a head tilt and ataxia was diagnosed with peripheral vestibular syndrome associated with an otitis media/interna...
June 25, 2018: BMC Veterinary Research
https://www.readbyqxmd.com/read/29937462/lymphoma-associated-hemophagocytic-syndrome-in-six-dogs
#18
Akihisa Suwa, Tetsuya Shimoda
Hemophagocytic syndrome (HPS) is a clinicopathological entity characterized by histiocytic proliferation, with marked hemophagocytosis in the reticuloendothelial organs. HPS caused by lymphoma is termed lymphoma-associated hemophagocytic syndrome (LAHS), and there are few reports on canine and feline LAHS. The objective of this study was to examine the clinical, diagnostic, and clinicopathologic features of LAHS in six dogs. The diagnostic criteria of LAHS consisted of lymphoma, bicytopenia or pancytopenia in the blood, and increased hemophagocytosis in the reticuloendothelial organs...
June 25, 2018: Journal of Veterinary Medical Science
https://www.readbyqxmd.com/read/29933739/-a-dog-related-demodex-spp-infestation-in-a-student-a-rare-demodex-case
#19
Fatma Esenkaya Taşbent, Bilal Dik
Demodicosis is an ectoparasitic cutaneous infestation of pilosebaceous unit caused by Demodex mites. Demodex spp. are considered to be pathogenic when they increase in number and infect dermis.They can be the cause of diseases such as pityriasis folliculorum, papulopustular rosacea, granulomatous rosacea, inflammatory papule, acne vulgaris, perioral dermatitis, blepharitis and folliculitis. These mites can be found in most mammals including human. Canine and feline demodicosis is a well-known example of severe dermatitis caused by the proliferation of Demodex mites...
April 2018: Mikrobiyoloji Bülteni
https://www.readbyqxmd.com/read/29917157/epidemiological-clinical-and-laboratory-features-of-toxocariasis-in-school-children-from-aragua-state-venezuela
#20
María Martínez, Jesica Montero, Adriana Pineda, Víctor Mijares, María Lares, Emily Catalano, Elizabeth Ferrer
Background: Toxocariasis is a widespread zoonosis caused by canine and feline Toxocara spp. In Venezuela, seroepidemiological studies in Aragua State have been carried out only in preschool children. The objective of this study was to determine the prevalence of anti-Toxocara spp. antibodies and identify clinical symptoms and risk factors of Toxocara spp. infection in school children in two municipalities of Aragua State of Venezuela. Methods: A cross-sectional field study with 259 children between 6 and 12 y of age was conducted in six schools in Aragua State...
June 1, 2018: Transactions of the Royal Society of Tropical Medicine and Hygiene
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