Bahar Banasaz, Razieh Zamzam, Davood Aghadoost, Khodayar Golabchi, Mohammadamin Morshedi, Mobina Bayat, Javid Sadri Nahand, Amirhossein Sheida, Reza Eshraghi, Zoha Rahimzadeh, Seyed Gholamabbas Mosavi, Pouya Goleij, Aryan Rezaee, Hamed Mirzaei
Pseudoexfoliation syndrome (PEX) is a critical clinical and biological extracellular matrix systemic disorder. Despite the unknown nature of PEX etiopathogenesis, it is proven to be associated with various genes and factors. The present research focused on analyzing the expression of miR and inflammatory cytokines in PEX. Serum and aqueous humor (AH) were collected prior to cataract surgery or trabeculectomy from 99 participants (64 with PEX glaucoma, and 35 controls). Real-time PCR was used for assessing the expression pattern of some miRNAs namely let-7b, miR-29a, miR-126, miR-34a, and miR-181a-5p...
August 2, 2023: Pathology, Research and Practice