T MacDonald, J J Sackett, M Gaskill-Shipley, R Rao, R Chaudhary, R Curry, J Forbes, N Andaluz, M Zuccarello, L Yogendran, S Sengupta, T D Struve Iii, R E Vatner, L E Pater, A E Mascia, J C Breneman, K Wang
PURPOSE/OBJECTIVE(S): Patients undergoing reirradiation (ReRT) for high grade glioma are at risk for tumor progression, pseudoprogression, and radiation necrosis. We investigated factors associated with neurologic events and disease control after re-irradiation with protons and photons at a single academic center. MATERIALS/METHODS: We reviewed records and MRIs of patients receiving scanning beam proton (since center opening in 2016) and photon (since 2015) reirradiation in ≥10 fractions for grade 3 anaplastic astrocytoma (AA) and grade 4 glioblastoma (GBM), excluding 1p19q co-deleted oligodendrogliomas and extensive multifocal/leptomeningeal disease...
October 1, 2023: International Journal of Radiation Oncology, Biology, Physics