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https://www.readbyqxmd.com/read/30315553/biomechanical-changes-of-tympanic-membrane-to-blast-waves
#1
Rong Z Gan
Eardrum or tympanic membrane (TM) is a multilayer soft tissue membrane located at the end of the ear canal to receive sound pressure and transport the sound into the middle ear and cochlea. Rupture of the TM is one of the most frequent injuries of the ear after blast exposure in military service members. The TM mechanical property changes induced by blast waves also affect progressive hearing loss in veterans. This chapter describes the biomechanical measurements and modeling of blast wave transduction through the ear and the TM mechanical property changes after blast exposure...
2018: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/30315218/fundamental-understanding-of-cellular-water-transport-process-in-bio-food-material-during-drying
#2
Md Imran H Khan, Troy Farrell, S A Nagy, M A Karim
Bio-food materials are heterogeneous in structure with cellular diversity, where the majority of the water is located in the intracellular spaces. Understanding of the nature of the microscopic behaviour of water transport is crucial to enhance the energy efficiency in food processing and obtain the better quality of processed food. In this research, apoplastic and symplastic transport of cellular water in the bio-food material during drying was investigated using 1 H-NMR-T2 relaxometry. We found that intracellular water (ICW) migrates from intracellular spaces to the intercellular spaces by progressive rupturing the cell membranes while drying at a higher temperatures (60 °C-70 °C)...
October 12, 2018: Scientific Reports
https://www.readbyqxmd.com/read/30312760/up-regulation-of-cox-2-and-mpges-1-by-27-hydroxycholesterol-and-4-hydroxynonenal-a-crucial-role-in-atherosclerotic-plaque-instability
#3
Simona Gargiulo, Daniela Rossin, Gabriella Testa, Paola Gamba, Erica Staurenghi, Fiorella Biasi, Giuseppe Poli, Gabriella Leonarduzzi
Atherosclerosis is currently understood to be mainly the consequence of a complicated inflammatory process at the different stages of plaque development. Among the several inflammatory molecules involved, up-regulation of the functional cyclooxygenase 2/membrane-bound prostaglandin E synthase 1 (COX-2/mPGES-1) axis plays a key role in plaque development. Excessive production of oxidized lipids, following low-density lipoprotein (LDL) oxidation, is a characteristic feature of atherosclerosis. Among LDLs, the oxysterol 27-hydroxycholesterol (27-OH) and the aldehyde 4-hydroxynonenal (HNE) substantially accumulate in the atherosclerotic plaque, contributing to its progression and instability through a variety of processes...
October 9, 2018: Free Radical Biology & Medicine
https://www.readbyqxmd.com/read/30309793/predictors-of-preterm-birth
#4
REVIEW
Yves Ville, Patrick Rozenberg
Cervical length (CL) measured by transvaginal ultrasound examination (TVUE) best identifies the risk for preterm birth (PTB). It identifies women at risk who can benefit from corticosteroids or in utero transfer. Early screening improves effectiveness of tocolysis. It reduces iatrogenicity and cost. In preterm premature rupture of membranes (PPROM), CL is devoid of infectious risk and predicts duration of the latency phase but not the risk of perinatal sepsis. Asymptomatic women at risk should be screened at a 2-week interval starting from 16 to 18 weeks, up to 24 weeks...
July 7, 2018: Best Practice & Research. Clinical Obstetrics & Gynaecology
https://www.readbyqxmd.com/read/30309412/-an-experiment-on-the-pathogenesis-of-early-biotrauma-in-ventilator-induced-lung-injury
#5
Jia Jia, Na Li, Guofu Li, Bin Zang
OBJECTIVE: To investigate the pathogenesis of early biotrauma in ventilator-induced lung injury (VILI). METHODS: Twenty-four 8-week-old male specific-pathogen-free Sprague-Dawley (SD) rats weighing 250-300 g were randomly divided into sham group (S group), conventional mechanical ventilation group (L group) and high tidal volume (VT) mechanical ventilation group (H group) with 8 rats in each group. All rats received tracheostomy after anesthesia. Rats in S group received no mechanical ventilation but breathe room air spontaneously...
September 2018: Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
https://www.readbyqxmd.com/read/30308685/obstetric-outcomes-among-syrian-refugees-a-comparative-study-at-a-tertiary-care-maternity-hospital-in-turkey
#6
Sule Ozel, Selen Yaman, Hatice Kansu-Celik, Necati Hancerliogullari, Nurgul Balci, Yaprak Engin-Ustun
OBJECTIVE:  The aim of this study was to analyze and compare obstetric and neonatal outcomes between Syrian refugees and ethnic Turkish women. METHODS:  Retrospective, observational study. A total of 576 Syrian refugees and 576 ethnic Turkish women were included in this study, which was conducted between January 2015 and December 2015 at a tertiary maternity training hospital in Ankara, Turkey. The demographic characteristics, obstetric and neonatal outcomes were compared...
October 11, 2018: Revista Brasileira de Ginecologia e Obstetrícia
https://www.readbyqxmd.com/read/30308501/cervical-and-amniotic-fluid-matrix-metalloproteinase-8-and-interleukin-6-concentrations-in-preterm-pregnancies-with-or-without-preterm-premature-rupture-of-membranes
#7
Emilia Holmström, Tarja Myntti, Timo Sorsa, Heidi Kruit, Juuso Juhila, Jorma Paavonen, Leena Rahkonen, Vedran Stefanovic
INTRODUCTION: Intra-amniotic inflammation is defined by elevated inflammatory biomarkers in the amniotic fluid (AF), either due to microbial invasion of the amniotic cavity (MIAC) or sterile inflammation. Amniocentesis being an invasive procedure, we wanted to investigate whether elevated matrix metalloproteinase-8 (MMP-8) or interleukin-6 (IL-6) concentrations could be detected from cervical fluid samples. MATERIALS AND METHODS: This prospective study included 67 women with singleton nondiabetic pregnancies with or without preterm premature rupture of membranes (PPROM) between 22+0 and 37+0 weeks of gestation...
October 11, 2018: Fetal Diagnosis and Therapy
https://www.readbyqxmd.com/read/30308113/porous-and-nonporous-silk-fibroin-sf-membranes-wrapping-for-achilles-tendon-at-repair-which-one-is-a-better-choice
#8
Shiyi Yao, Yuanlong Xie, Lingfei Xiao, Lin Cai, Zhaocheng Ma
Two types of silk fibroin (SF) membranes were developed for tendon repair: porous and nonporous SF membranes. The objective of this study was to compare the efficiency of these two films according to the ability of tendon regeneration using a rat Achilles tendon (AT) rupture suture wrapping model. The in vitro tests were conducted, and theSF membranes were proved to be with ultimate-biodegradability, good-biocompatibility and without toxicity. In vivo, 12 Sprague Dawley rats were used to create a rat AT rupture suture model wrapped by SF membranes...
October 11, 2018: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
https://www.readbyqxmd.com/read/30305790/spontaneous-colonic-rupture-related-to-the-segmental-absence-of-muscularis-propria-in-an-adult
#9
Chih-En Tseng, Shih-Pin Lin, Hou-Chi Huang, Mei-Chung Chin
Colonic perforation is a medical emergency that may be fatal if surgery cannot be performed in a timely manner. Colonic rupture in adults is caused by primary (idiopathic) and secondary factors. Although the segmental absence of muscularis propria (SAMP) is a recognized cause of secondary colonic rupture in neonates and infants, few cases have been reported in adults. Here, we present the case of a large colonic rupture caused by SAMP in a 60-year-old woman and a review of the literature. We suggest that SAMP should be included in the differential diagnosis of large perforation and/or periperforation membranous thinning of the colonic wall in adults...
October 2018: Ci Ji Yi Xue za Zhi, Tzu-chi Medical Journal
https://www.readbyqxmd.com/read/30304023/modification-of-cellular-membranes-conveys-cryoprotection-to-cells-during-rapid-non-equilibrium-cryopreservation
#10
Jan Huebinger
Rapid cooling and re-warming has been shown promising to cryopreserve living cells, which cannot be preserved by conventional slow freezing methods. However, success is limited by the cytotoxicity of highly concentrated cryoprotective agents. Recent results have shown that cryoprotective agents do not need to suppress intracellular ice crystals completely to allow for survival after cryopreservation. Cryoprotective agents like DMSO or ethylene glycol can also lead to a tolerance of cells towards intracellular ice...
2018: PloS One
https://www.readbyqxmd.com/read/30303742/drastic-induction-of-mmp-7-by-cortisol-in-the-human-amnion-implications-for-membrane-rupture-at-parturition
#11
Lu-Yao Wang, Wang-Sheng Wang, Ya-Wei Wang, Jiang-Wen Lu, Yi Lu, Chu-Yue Zhang, Wen-Jiao Li, Kang Sun, Hao Ying
Preterm premature rupture of fetal membranes precedes 30-40% of preterm births. Activation of matrix metalloproteases (MMPs) is the one of the major causes of extracellular matrix (ECM) degradation in membrane rupture. Increased cortisol, regenerated by 11β-hydroxysteroid dehydrogenase 1 in the amnion at parturition, is known to participate in a number of parturition-pertinent events. However, whether cortisol has a role in the regulation of MMPs in the membranes is not known. Here, we addressed this issue using human amnion tissue, the most tensile layer of the membranes...
October 10, 2018: FASEB Journal: Official Publication of the Federation of American Societies for Experimental Biology
https://www.readbyqxmd.com/read/30303159/primary-intrauterine-dysgerminoma-in-a-pregnant-woman-a-rare-case-report
#12
Mojgan Akbarzadeh-Jahromi, Fatemeh Sari Aslani, Fatemesadat Najib, Shahla Hosseini
Primary extraovarian dysgerminoma is very rare. Nearly all reported uterine germ cell tumors are nondysgerminoma. Herein, we reported a primary intrauterine dysgerminoma. A 21-year-old pregnant woman G2 L1 with a gestational age of 33 weeks referred to an obstetric ward with a chief complaint of labor pain and membrane rupture. Ultrasonography showed a large hypoechoic lobulated area adjacent to the lower part of her uterus. She underwent an operation and a huge mass was detected in her uterus, which was extended to her pelvic floor...
October 2018: Indian Journal of Pathology & Microbiology
https://www.readbyqxmd.com/read/30301357/the-patterns-of-self-reported-maternal-complications-in-indonesia-are-there-rural-urban-differences
#13
Vitri Widyaningsih, Khotijah Khotijah
INTRODUCTION: Specific and targeted intervention is needed to reduce the relatively high maternal mortality and morbidity in Indonesia. The apparent rural-urban disparities might require different intervention strategies. Therefore, this study aims to assess patterns and sociodemographic determinants of self-reported maternal morbidity in rural and urban areas. METHODS: Data from the Indonesian Demographic and Health Survey 2012 were analyzed. In this cross-sectional survey, maternal morbidity status and sociodemographic factors were obtained through questionnaire-based interviews...
October 2018: Rural and Remote Health
https://www.readbyqxmd.com/read/30298414/improved-results-of-acl-primary-repair-in-one-part-tears-with-intact-synovial-coverage
#14
Atesch Ateschrang, Anna Janine Schreiner, Sufian S Ahmad, Steffen Schröter, Michael T Hirschmann, Daniel Körner, Sandro Kohl, Ulrich Stöckle, Marc-Daniel Ahrend
PURPOSE: It was the aim to assess the influence of synovial sheath disruption on early failure of primary anterior cruciate ligament (ACL) repair. It was hypothesized that more-part ACL tears with disruption of the synovial sheath are associated with a higher risk of failure after primary ACL repair. METHODS: A cohort study was conducted comprising patients with primal ACL tears undergoing primary ACL repair and dynamic intraligamentary stabilization (DIS). The patients were stratified into three groups: A-one-part rupture with intact synovial membrane (n = 50), B-two-part ruptures resultant to separation of the ACL into two main bundles with synovial membrane tearing (n = 52) and C-more parts involving multilacerated ruptures with membrane disruption (n = 22)...
October 8, 2018: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/30294789/the-development-of-the-cloaca-in-the-human-embryo
#15
Nutmethee Kruepunga, Jill P J M Hikspoors, Hayelom K Mekonen, Greet M C Mommen, Krai Meemon, Wattana Weerachatyanukul, Somluk Asuvapongpatana, S Eleonore Köhler, Wouter H Lamers
Subdivision of cloaca into urogenital and anorectal passages has remained controversial because of disagreements about the identity and role of the septum developing between both passages. This study aimed to clarify the development of the cloaca using a quantitative 3D morphological approach in human embryos of 4-10 post-fertilisation weeks. Embryos were visualised with Amira 3D-reconstruction and Cinema 4D-remodelling software. Distances between landmarks were computed with Amira3D software. Our main finding was a pronounced difference in growth between rapidly expanding central and ventral parts, and slowly or non-growing cranial and dorsal parts...
October 7, 2018: Journal of Anatomy
https://www.readbyqxmd.com/read/30293468/impact-of-oocyte-donation-on-obstetric-and-perinatal-complications-in-twin-pregnancies
#16
Felix Boria, Maria de la Calle, Marcos Cuerva, Angela Sainz, Jose Luis Bartha
AIM: To evaluate obstetric and perinatal outcomes of twin pregnancies obtained after in vitro fertilization with donated oocytes. METHODS: This is a case-control study comparing 50 women with twin pregnancies after oocyte donation and 50 women after in vitro fertilization with autologous oocytes. Clinical records were reviewed and obstetric and perinatal outcome variables including rates of preeclampsia, gestational diabetes, pregnancy induced hypertension, preterm delivery, premature rupture of membranes, cesarean delivery, birth weight, Apgar score, pH test were compared...
October 8, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/30293462/interleukin-6-measured-using-the-automated-electrochemiluminescence-immunoassay-method-for-the-identification-of-intra-amniotic-inflammation-in-preterm-prelabor-rupture-of-membranes
#17
Ivana Musilova, Ctirad Andrys, Magdalena Holeckova, Veronika Kolarova, Lenka Pliskova, Marcela Drahosova, Radka Bolehovska, Radovan Pilka, Karel Huml, Teresa Cobo, Bo Jacobsson, Marian Kacerovsky
INTRODUCTION: We aimed to compare the amniotic fluid interleukin (IL)-6 concentrations measured using the automated electrochemiluminescence immunoassay method and ELISA, and to establish an IL-6 concentration cut-off value for intra-amniotic inflammation (IAI) in preterm prelabor rupture of membranes (PPROM), which can be used in the automated electrochemiluminescence immunoassay method. MATERIALS AND METHODS: A total of 120 women with PPROM were included in this study...
October 8, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/30293293/-perinatal-outcomes-of-thoraco-amniotic-shunting-for-severe-primary-fetal-hydrothorax
#18
X Wei, M Meng, G Zou, F H Zhou, Y J Yang, Y Zhang, M Z Yuan, F Y Wu, L M Sun
Objective: To evaluate the safety and perinatal outcomes of thoracoamniotic shunting in the treatment of fetuses with severe primary hydrothorax. Methods: 22 cases of suspected severe primary fetal hydrothorax which underwent thoraco-amniotic shunting in Shanghai First Maternity and Infant Hospital, Fetal Medicine Unit and Prenatal Diagnosis Center from January 2012 to December 2017 were analyzed retrospectively. Hydrothorax associated with structural or chromosomal abnormalities, infections and immune fetal hydrops were excluded...
September 25, 2018: Zhonghua Fu Chan Ke za Zhi
https://www.readbyqxmd.com/read/30292321/histological-investigations-on-the-dura-mater-vascular-system-of-mice
#19
Badreddine Mecheri, Frank Paris, Hermann Lübbert
The human dura mater encephali is a well innervated and vascularized membrane. Its vascular system plays a crucial role in disorders and pathological cases like dural hematoma, meningitis, and different headache types. To investigate these diseases mouse models are increasingly being used. However, the literature on the vascular system of the mouse dura mater is sparse and explicit studies concerned exclusively with its vasculature are lacking. Here we present a detailed light and scanning electron microscopic investigation of the supratentorial dura mater of the mouse species, with a focus on the largest part of it, the parietal dura mater...
October 3, 2018: Acta Histochemica
https://www.readbyqxmd.com/read/30291524/evaluation-of-silicon-membranes-for-extracorporeal-membrane-oxygenation-ecmo
#20
Emily N Abada, Benjamin J Feinberg, Shuvo Roy
While extracorporeal membrane oxygenation (ECMO) is a valuable therapy for patients with lung or heart failure, clinical use of ECMO remains limited due to hemocompatibility concerns with pro-coagulatory hollow fiber membrane geometries. Previously, we demonstrated the feasibility of silicon nanopore (SNM) and micropore (SμM) membranes for transport between two liquid-phase compartments in blood-contacting devices. Herein, we investigate various pore sizes of SNM and SμM membranes - alone or with a polydimethylsiloxane (PDMS) protective coating - for parameters that determine suitability for gas exchange...
October 5, 2018: Biomedical Microdevices
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