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Preterm pregnancy

Sinan Ates, Mahmut Alp Karahan, Nuray Altay, Kazim Akelci, Nagehan Ikiz, Bulent Guzel, Mandeley Wilhelmina Ozer, Haci Durmus Yilmaz
OBJECTIVE: Scorpion stings remain a serious health problem in many parts of the world. There is very limited information regarding the effects of therapies delivered for scorpion stings in pregnant women on the mother and fetus. They can cause acute conditions such as fetal loss, preterm delivery, or placental abnormalities and can also result in other conditions that may have an effect on the baby in the long term. MATERIALS AND METHODS: In this study the medical records of 24 pregnant women who were admitted to the emergency room at Suruç State Hospital due to scorpion stings between January 1, 2013 and January 1, 2014 were retrospectively reviewed...
October 2018: Taiwanese Journal of Obstetrics & Gynecology
Li-Jie Xiang, Yan Wang, Guo-Yuan Lu, Qin Huang
OBJECTIVE: Microangiopathy is common after a long duration in type 1 diabetes mellitus (T1DM). Pregnancies with end-age vascular complications are a big challenge to multidisciplinary physicians. The objective of this study was to assess the risk of microangiopathy for adverse pregnancy outcome in T1DM. MATERIALS AND METHODS: PubMed, EMBASE, and Cochrane Library databases were searched for relevant articles appearing in the literature up to October 1, 2017. Analysis of cohort studies were performed with Review Manager 5...
October 2018: Taiwanese Journal of Obstetrics & Gynecology
Olivier Blanchard, Séverine Deguen, Wahida Kihal-Talantikite, Romain François, Denis Zmirou-Navier
BACKGROUND: Prenatal exposure to outdoor air pollution has been shown to have health effects in many studies; low birth weight, preterm delivery, small for gestational age, and stillbirth are the most often cited. However, exposure of pregnant women is difficult to quantify, especially with regard to their mobility, which is rarely taken into account in epidemiological studies. This study aimed to assess the impact of mobility of pregnant women living in Paris, France, on their exposure estimates to nitrogen dioxide (NO2 )...
October 19, 2018: Environmental Health: a Global Access Science Source
Xingchen Zhou, Xiaoqian Yang, Huihui Chen, Xuhong Fang, Xipeng Wang
BACKGROUND: Although vaginal repair has been conducted to manage caesarean scar diverticula, most studies evaluated only the gynaecological outcomes post-surgery, and their obstetrical outcomes were unknown. This study aimed to evaluate the obstetrical outcomes in vaginal repair-treated caesarean scar diverticula patients. METHODS: A series of 51 symptomatic women with caesarean scar defects or a thickness of the remaining muscular layer of less than 3 mm according to transvaginal ultrasound were included...
October 19, 2018: BMC Pregnancy and Childbirth
Pieta Näsänen-Gilmore, Marika Sipola-Leppänen, Marjaana Tikanmäki, Hanna-Maria Matinolli, Johan G Eriksson, Marjo-Riitta Järvelin, Marja Vääräsmäki, Petteri Hovi, Eero Kajantie
Very preterm birth, before the gestational age (GA) of 32 weeks, increases the risk of obstructed airflow in adulthood. We examined whether all preterm births (GA<37 weeks) are associated with poorer adult lung function and whether any associations are explained by maternal, early life/neonatal, or current life factors. Participants of the ESTER Preterm Birth Study, born between 1985 and 1989 (during the pre-surfactant era), at the age of 23 years participated in a clinical study in which they performed spirometry and provided detailed medical history...
2018: PloS One
Ahizechukwu C Eke, Jeanne Sheffield, Ernest M Graham
INTRODUCTION: To evaluate whether there are additional benefits of 17-hydroxyprogesterone caproate (17-OHPC) supplementation in preventing recurrent spontaneous preterm birth in women with a prophylactic cerclage. MATERIAL AND METHODS: Electronic databases (MEDLINE, Scopus, ClinicalTrials gov, PROSPERO, EMBASE, Scielo and the Cochrane Central Register of Controlled Trials) were searched for studies published before June 2018. Keywords included "preterm birth," "prophylactic cerclage," "history-indicated cerclage," "pregnancy" and "17-hydroxyprogesterone caproate...
October 19, 2018: Acta Obstetricia et Gynecologica Scandinavica
Ling-Wei Chen, Roisin Fitzgerald, Celine M Murrin, John Mehegan, Cecily C Kelleher, Catherine M Phillips
Background: Maternal caffeine intake is associated with adverse birth outcomes, but in most studies the primary caffeine source is coffee; the influence of tea caffeine remains unclear. Objective: The aim of the study was to examine the association between maternal caffeine intake and birth outcomes in a population with tea as the predominant caffeine source. Design: Data from 941 Irish mother-child pairs of the Lifeways Cross Generation Cohort Study were examined...
October 19, 2018: American Journal of Clinical Nutrition
Natalie Suff, Lisa Story, Andrew Shennan
Preterm birth, defined as birth occurring prior to 37 weeks gestation, is a serious obstetric problem accounting for 11% of pregnancies worldwide. It is associated with significant neonatal morbidity and mortality. Predictive tests for preterm birth are incredibly important, given the huge personal, economic, and health impacts of preterm birth. They can provide reassurance for women who are unlikely to deliver early, but they are also important for highlighting those women at higher risk of premature delivery so that we can offer prophylactic interventions and help guide antenatal management decisions...
September 28, 2018: Seminars in Fetal & Neonatal Medicine
Ilaria Fantasia, Walkyria Andrade, Argyro Syngelaki, Ranjit Akolekar, Kypros H Nicolaides
OBJECTIVES: To investigate the relationship between fetal congenital heart defects (CHD) and placental perfusion assessed by uterine artery pulsatility index (UtA-PI) in relation to development of preeclampsia (PE). METHODS: This was a prospective screening study in singleton pregnancies at 19-24 weeks' gestation. Transvaginal ultrasound was used to measure the UtA-PI and the values were converted into multiples of the normal median (MoM). Median MoM values in pregnancies with fetuses with isolated major CHD were compared to those without CHD in relation to development of PE...
October 17, 2018: Ultrasound in Obstetrics & Gynecology
Liang Wang
Serial cervical length (CL) measurement in mid-trimester is recommended in post-conization pregnancy to estimate the risk of spontaneous preterm birth (SPTB). A short mid-trimester cervix (CL < 25 mm) has been considered as a strong predictor for SPTB. However, the low incidence of short cervix limits the utility of mid-trimester CL measurement in prediction of SPTB. A great proportion of women who develop SPTB don't have a short mid-trimester cervix. Therefore, this study was aimed to investigate the additional value of serial CL measurement in predicting SPTB in addition to detecting short cervix alone...
October 17, 2018: Scientific Reports
Maia Brik, Irene Fernández-Buhigas, Aránzazu Martin-Arias, Marina Vargas Terrones, Rubén Barakat, Belén Santacruz
OBJECTIVE: to evaluate differences in maternal weight gain and fetal cardiac function according to exercise during pregnancy METHODS: A randomized controlled trial was performed at Hospital de Torrejón, Madrid, including 120 pregnant women, allocated into Exercise Group (EG) and Control Group (CG). The primary outcome was maternal weight. Secondary outcomes included caesarean section, preterm delivery, induction of labor, birth weight and fetal cardiac function parameters. A sample size of 45 (90 both groups) was planned to detect differences in maternal weight gain of at least 1 Kg, with a power of >80% (>0...
October 17, 2018: Ultrasound in Obstetrics & Gynecology
Renata H Benjamin, Laura E Mitchell, Mark A Canfield, Adrienne T Hoyt, Dejian Lai, Tunu A Ramadhani, Suzan L Carmichael, Amy P Case, D Kim Waller
OBJECTIVE: To evaluate the relationships between maternal fish consumption and pregnancy outcomes in a large, population-based sample of women in the USA. DESIGN: We collected average fish consumption prior to pregnancy using a modified version of the semi-quantitative Willett FFQ. We estimated adjusted OR (aOR) and 95 % CI for associations between different levels of fish consumption and preterm birth (<37 weeks), early preterm birth (<32 and <35 weeks) and small-for-gestational-age infants (SGA; <10th percentile)...
October 17, 2018: Public Health Nutrition
Maryam Nesari, Joanne K Olson, Ben Vandermeer, Linda Slater, David M Olson
BACKGROUND: Evidence relating maternal history of abuse before pregnancy with pregnancy outcomes is controversial. This study aims to examine the association between maternal histories of abuse before pregnancy and the risk of preterm delivery and low birth weight. METHODS: We searched Subject Headings and keywords for exposure and the outcomes through MEDLINE, EMBASE, Cochrane Database of Systematic Reviews, Cochrane Central Register of Controlled Trials, Psycinfo, CINAHL, Scopus, PILOTS, ProQuest Dissertations & Theses Global and Web of Science Core Collection in April 2017...
October 16, 2018: BMC Pregnancy and Childbirth
Vera Ehrenstein, Nickolaj Risbo Kristensen, Brigitta Ursula Monz, Barry Clinch, Andy Kenwright, Henrik Toft Sørensen
BACKGROUND: Prenatal exposure to influenza or fever is associated with risk of congenital malformations. Oseltamivir is used to treat influenza and to provide post-exposure prophylaxis. We examined the association between oseltamivir use during pregnancy and birth outcomes. METHODS: This was a nationwide registry-based prevalence study with individual level data linkage, in a setting of universal health care access. We included all recorded pregnancies in Denmark in 2002-2013, and used data from population registries to examine associations between dispensings for oseltamivir during pregnancy (first trimester, second/third trimester, none) and congenital malformations, foetal death, preterm birth, foetal growth, and low 5-min Apgar score...
October 16, 2018: BMC Infectious Diseases
Faruk Uguz, Goksen Yuksel, Ozge Sahmelikoglu Onur, Cagatay Karsidag, Kazim Gezginc, Nazile Arpaci
OBJECTIVE: The objective of the present study was to compare neonatal outcomes including gestational age, birth weight and hospitalization of newborns of pregnant women with treated with antidepressants and untreated panic disorder. METHODS: The study sample included 146 pregnant women (44 patients with panic disorder treated with antidepressants, 52 patients with untreated panic disorder, and 50 healthy controls). Panic disorder was diagnosed by means of the Structured Clinical Interview for the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition...
October 9, 2018: Comprehensive Psychiatry
(no author information available yet)
OBJECTIVES: to investigate whether specific nucleoside reverse transcriptase inhibitor (NRTI) backbones are associated with risk of adverse pregnancy outcomes among pregnant women starting antiretroviral therapy (ART) DESIGN:: Seven observational studies across eight European countries of pregnancies in HIV-positive women METHODS:: Individual-level data were pooled on singleton pregnancies conceived off-ART in which a single combination ART regimen was initiated ≥2 weeks before delivery, and ending in a live birth in 2008-2014...
October 15, 2018: AIDS
Sebastian Quezada, Margie Castillo-Melendez, David W Walker, Mary Tolcos
KEY POINTS: Normal folding of the cerebral cortex (gyrification) is fundamental for neurodevelopment. Some molecular mechanisms of gyrification during fetal development have been identified, but the impact of maternal health and the intrauterine environment has been largely overlooked. Recent evidence suggests that the intrauterine environment has a significant impact on the normal folding of the fetal cerebral cortex. This article reviews evidence for the effect of the most common intrauterine alterations on the normal development of the cortical folding in the fetus...
October 16, 2018: Journal of Physiology
Kingi Mochache, Muthoni Mathai, Onesmus Gachuno, Ann Vander Stoep, Manasi Kumar
[This corrects the article DOI: 10.1186/s12991-018-0202-6.].
2018: Annals of General Psychiatry
Hagar Rahel Haviv, Joanne Said, Ben Willem Mol
Infants born in the late preterm period and via non-labour caesarean section in the early term period are at increased risk of respiratory morbidity when compared to their term-born counterparts. The morbidity in these infants is less frequent and severe than in early preterm infants. Antenatal corticosteroids reduce respiratory morbidity in these populations; however, the magnitude of the reduction appears to be small and predominantly in the self-limiting condition of transient tachypnoea of the neonate. The smaller benefit, along with possible harmful effects of corticosteroids, raises a question about the role of antenatal corticosteroids in this population...
October 4, 2018: Seminars in Fetal & Neonatal Medicine
Damien Subtil, Gilles Brabant, Emma Tilloy, Patrick Devos, Frédérique Canis, Annie Fruchart, Marie-Christine Bissinger, Jean-Charles Dugimont, Catherine Nolf, Christophe Hacot, Sophie Gautier, Jérôme Chantrel, Marielle Jousse, David Desseauve, Jean Louis Plennevaux, Christine Delaeter, Sylvie Deghilage, Anne Personne, Emmanuelle Joyez, Elisabeth Guinard, Eric Kipnis, Karine Faure, Bruno Grandbastien, Pierre-Yves Ancel, François Goffinet, Rodrigue Dessein
BACKGROUND: Preterm delivery during pregnancy (<37 weeks' gestation) is a leading cause of perinatal mortality and morbidity. Treating bacterial vaginosis during pregnancy can reduce poor outcomes, such as preterm birth. We aimed to investigate whether treatment of bacterial vaginosis decreases late miscarriages or spontaneous very preterm birth. METHODS: PREMEVA was a double-blind randomised controlled trial done in 40 French centres. Women aged 18 years or older with bacterial vaginosis and low-risk pregnancy were eligible for inclusion and were randomly assigned (2:1) to three parallel groups: single-course or triple-course 300 mg clindamycin twice-daily for 4 days, or placebo...
October 12, 2018: Lancet
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