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the rheumatologist

Nida Saleem, Tahir Aziz Ahmed, Mukarram Bashir, Muhammad Omair Riaz, Ali Hamid
OBJECTIVE: To compare the frequency and the functional state of the collagen II reactive T cells with disease activity in rheumatoid arthritis patients and healthy controls. METHODS: This case-control cross-sectional study was carried out at the Department of Immunology; Armed Forces Institute of Pathology, Rawalpindi, Pakistan, from June to October 2014. Rheumatologist from Rehmat Noor Rheumatology Clinic, a private health facility of the city, was requested to send in patients with clinical diagnosis of rheumatoid arthritis...
August 2018: JPMA. the Journal of the Pakistan Medical Association
Chantal Plomb-Holmes, Philippe Clavert, Frank Kolo, Eileen Tay, Alexandre Lädermann, French Society Of Arthroscopy
Ultrasound (US) imaging is an efficient, easy to use and inexpensive tool allowing for facilitated diagnosis and management of the painful shoulder. It remains primarily used by radiologists and rheumatologists, despite having shown excellent diagnostic accuracy when used by different medical specialities in their office-based consultation. It also has advantages over other imaging modalities in the evaluation of the post-operative shoulder for rotator cuff integrity and correct anchor and suture placement, as well as rotator cuff analysis following arthroplasty...
August 11, 2018: Orthopaedics & Traumatology, Surgery & Research: OTSR
Mehret Birru Talabi, Megan E B Clowse, Susan J Blalock, Larry Moreland, Nalyn Siripong, Sonya Borrero
OBJECTIVE: To determine contraception use among a cohort of reproductive-age women (18-50 years) with rheumatic diseases. METHODS: We conducted a study of administrative data from a single, large medical center between years 2013 and 2014. Women who had 1 of 21 rheumatic disease diagnoses and had at least 2 outpatient rheumatology visits were included in this analysis. We used logistic regression analyses to evaluate adjusted associations between the use of prescription contraception, use of potentially fetotoxic medications, and visits with rheumatologists, primary care providers (PCP), and gynecologists...
August 14, 2018: Arthritis Care & Research
Ichiro Katayama
We have reported characteristic cutaneous manifestations of Sjögren syndrome (SS) with special references to autoimmune anhidrosis or hypoidrosis and related mucocutaenous manifestations in addition to annular erythema or cutaneous vasculitis. Although significance of cutaneous manifestations of SS has been gradually recognized in rheumatologists, sudomotor function has not been fully evaluated and recognized in the diagnosis of SS except for dermatologists. SS is a relatively underestimated collagen disease in contrast to SLE, systemic sclerosis, or dermatomyositis, special care should be needed not to make misdiagnosis of SS when we see the patients with common skin disease such as, drug eruption, infections skin disease or xerosis in the daily practice...
August 10, 2018: Allergology International: Official Journal of the Japanese Society of Allergology
Thurayya Arayssi, Manale Harfouche, Andrea Darzi, Samar Al Emadi, Khaled A Alnaqbi, Humeira Badsha, Farida Al Balushi, Carole Dib, Bassel Elzorkany, Hussein Halabi, Mohammed Hammoudeh, Wissam Hazer, Basel Masri, Mira Merashli, Mohammed Omair, Nelly Salloum, Imad Uthman, Sumeja Zahirovic, Nelly Ziade, Raveendhara R Bannuru, Timothy McAlindon, Mohamed A Nomier, Jasvinder A Singh, Robin Christensen, Peter Tugwell, Holger Schünemann, Elie A Akl
Clinical practice guidelines can assist rheumatologists in the proper prescription of newer treatment for rheumatoid arthritis (RA). The objective of this paper is to report on the recommendations for the management of patients with RA in the Eastern Mediterranean region. We adapted the 2015 American College of Rheumatology guidelines in two separate waves. We used the adolopment methodology, and followed the 18 steps of the "Guidelines 2.0" comprehensive checklist for guideline development. For each question, we updated the original guidelines' evidence synthesis, and we developed an Evidence Profile (EP) and an Evidence to Decision (EtD) table...
August 10, 2018: Clinical Rheumatology
Jonathan H Chung, Jonathan G Goldin
Idiopathic pulmonary fibrosis (IPF) is a progressive fibrosing interstitial lung disease (ILD). In this review, we describe the central role of high-resolution computed tomography (HRCT) in the diagnosis of IPF and discuss how communication between pulmonologists and radiologists might be improved to make the interpretation of HRCT scans more effective. Clinical information is important in the interpretation of HRCT scans, as the likelihood that specific radiologic features reflect IPF is not absolute, but dependent on the clinical context...
August 10, 2018: Lung
Zhenyu Li, Ting Fu, Lin Li, Yafei Cui, Chen Dong, Jing Li, Zhifeng Gu
Dry eye and dry mouth are typical clinical symptoms of primary Sjögren's syndrome (pSS), yet not considered in the assessment of severity and predictors in China. This study aimed to investigate the prevalence, severity, and potential predictors of dry eye/dry mouth among Chinese pSS patients. A cross-sectional study was conducted from the Affiliated Hospital of Nantong University. A series of questionnaires were applied: Ocular Surface Disease Index (OSDI), EULAR Sjogren's Syndrome Patient Reported Index (ESSPRI)-dry mouth items, fatigue severity scale (FSS), the 10 cm visual analog scale (VAS)...
August 9, 2018: Clinical Rheumatology
Juliana C O A Ferreira, Vitor C Trindade, Graciela Espada, Zoilo Morel, Eloisa Bonfá, Claudia S Magalhães, Clovis Artur Silva
To assess epidemiology and management practices of Latin America Pediatric Rheumatologists (LAPR) about childhood-onset systemic lupus erythematosus (cSLE). A cross-sectional study was performed in 288 LAPR PANLAR members based on online survey about cSLE practices. The response rate of web-based survey by LAPR was 170/288(59%) and the majority worked in university hospitals (63%). The ACR and/or SLICC classification criteria (99%) and disease activity tools (97%) were almost universally used by LAPR, whereas damage index (70%) and CHAQ (58%) instruments were less frequently used...
August 9, 2018: Clinical Rheumatology
Eric S Zollars, Madison Hyer, Bethany Wolf, Russell Chapin
Objective: Arthritis in SLE is poorly described, and there is no objective measure for quantification of arthritis. In this pilot study, we aim to assess the utility of the Rheumatoid Arthritis MRI Scoring System (RAMRIS) for the quantification of lupus arthritis. Methods: Patients were eligible for entry into the study if they were evaluated at the Medical University of South Carolina Lupus Center and determined by their treating rheumatologist to have active hand arthritis due to SLE...
2018: Lupus Science & Medicine
Lídia Teixeira, Cristina Fonseca, Sandra Sousa, Filipe Vinagre, Ana Cordeiro, Pedro Gonçalves, Maria José Santos, José Canas da Silva
Hepatitis C virus (HCV) infection is a major public health problem. Because Tumour Necrosis Factor (TNF) seems to have an important role in immune response to HCV infection, suppression by TNFi (TNF inhibitors) may pose a potential worsening of chronic HCV infection. We report our experience with 3 cases of patients with chronic HCV infection and advanced liver disease, with different Rheumatic diseases, treated with a TNFi, etanercept (ETN), for a period ranging from 4 months to 4 years without hepatitis C treatment and, in two of them, concomitant therapy with direct-acting antiviral agents (DAA) and afterwards...
April 2018: Acta Reumatológica Portuguesa
Rehab Ali Ibrahim, Nour El-Hoda Hussien Abdalla, Engy Amr Husssein Shabaan, Noha Bassiouny Hassan Mostafa
BACKGROUND: Scleroderma or systemic sclerosis (SSc) is a rare systemic autoimmune disease. Many conditions mimic the presentation of SSc, especially skin thickening and fibrosis. One of these conditions is scleredema, a rare collagen and mucin deposition disorder which was found to be associated with diabetes mellitus, streptococcal infection or monoclonal gammopathy. CASE PRESENTATION: A 55 years old female presented with insidious onset and progressive course of diffuse skin thickening of face, neck, arms, forearms, thighs, chest, back, and sparing both hands and feet of 6 years duration associated with arthralgia, dysphagia and dyspnea on exertion of 1-year duration...
August 7, 2018: Current Rheumatology Reviews
C Fiehn, H-M Lorenz
No abstract text is available yet for this article.
August 2018: Zeitschrift Für Rheumatologie
Kristy S Yap, Justine Y Ye, Suzanne Li, Dafna D Gladman, Vinod Chandran
OBJECTIVE: We aimed to determine the agreement between rheumatologist-judged inflammatory back pain (IBP) and criteria defining IBP in patients with psoriatic arthritis (PsA) and predictive value of IBP in identifying axial involvement in PsA. METHODS: Using prospectively collected data, we investigated the agreement between rheumatologist judgement of IBP and IBP criteria (Calin, Rudwaleit and Assessment of Spondyloarthritis International Society) using the kappa coefficient...
August 4, 2018: Annals of the Rheumatic Diseases
Rok Ješe, Katja Perdan-Pirkmajer, Alojzija Hočevar, Žiga Rotar, Sanja Markez, Milena Pavič-Nikolič, Matija Tomšič
Epidemiological data for rheumatoid arthritis (RA) differ according to ethnicity and geographical region. Moreover, despite of clear RA management guidelines, the implementation of treat-to-target (T2T) strategy often remains incomplete. Our objectives were to determine the incidence rate of RA, the clinical characteristics, and the level of adherence to the T2T guidelines in Slovenia. We analyzed prospectively the collected data of adult patients diagnosed with RA from 2014 through 2016 at the Department of Rheumatology, University Medical Centre Ljubljana, Ljubljana, Slovenia...
August 2, 2018: Clinical Rheumatology
MaryAnn Zhang, Monica A Pessina, Jay B Higgs, Eugene Y Kissin
Background: We evaluated the risk of lateral circumflex femoral artery (LCFA) injury during ultrasound-guided intra-articular hip injections. Methods: This study was divided into three parts. (1) Four ultrasound-guided hip injections were performed on human cadavers. With needles in place, tissues were dissected to expose the LCFA. (2) Ultrasound-trained rheumatologists marked a planned needle trajectory from skin to hip joint on live human ultrasound images during an Observed Structured Clinical Examination (OSCE)...
April 2018: Journal of Medical Ultrasound
Jane C Burns, Tomoyo Matsubara
PURPOSE OF REVIEW: Kawasaki disease presents many challenges to the diverse group of physicians who care for these patients including infectious disease specialists, rheumatologists, and cardiologists. Here we review some of the progress being made toward improved understanding of disease pathogenesis, treatment, and long-term outcomes. RECENT FINDINGS: Epidemiologic studies in different populations documented increasing numbers of cases in countries with high physician awareness of the disease...
July 30, 2018: Current Opinion in Pediatrics
Valderilio Feijó Azevedo, Alejandra Babini, Carlo V Caballero-Uribe, Gilberto Castañeda-Hernández, Cecilia Borlenghi, Heather E Jones
BACKGROUND/HISTORICAL PERSPECTIVE: Availability of biologic disease-modifying antirheumatic drugs (bDMARDs) has improved clinical outcomes in rheumatoid arthritis, but it also increased the cost of treatment. Biosimilars, the regulated copies of biologic products, have a potential to reduce health care costs and expand access to treatment. However, because of a complex development process, biosimilars can be considered only those noninnovator biologics with satisfactory supporting evidence (ranging from structural to clinical), as outlined in the recommendations by the World Health Organization (WHO)...
July 27, 2018: Journal of Clinical Rheumatology: Practical Reports on Rheumatic & Musculoskeletal Diseases
Fabiola Atzeni, Rossella Talotta, Valeria Nucera, Francesca Marino, Elisabetta Gerratana, Donatella Sangari, Ignazio Francesco Masala, Piercarlo Sarzi-Puttini
A new class of oral synthetic drugs has been developed for the treatment of rheumatoid arthritis (RA) with the aim of blocking the JAK-STAT system. Tofacitinib and baricitinib have been approved for the treatment RA patients who inadequately respond to methotrexate or anti-tumour necrosis factor drugs. The aim of this narrative review is to summarise the data concerning the drugs' basic mechanisms and clinical trial results in order to inform clinicians about the serious and non-serious adverse events associated with JAK inhibitors...
July 30, 2018: Expert Review of Clinical Immunology
Erin M Wilfong, Robert J Lentz, Adam Guttentag, James J Tolle, Joyce E Johnson, Jonathan A Kropski, Peggy L Kendall, Timothy S Blackwell, Leslie J Crofford
Interstitial lung disease remains a cause of significant morbidity and mortality in patients with connective tissue disease associated ILD. While some patients meet clear classification criteria for a systemic rheumatic disease, there is a subset of patients not meeting classification criteria who still benefit from immunosuppressive therapy. In 2015, the American Thoracic Society and European Respiratory Society described classification criteria for interstitial pneumonia with autoimmune features (IPAF) to identify patients with lung predominant connective tissue disease who lack sufficient features of a systemic rheumatic disease to meet classification criteria...
July 29, 2018: Arthritis & Rheumatology
Simran Kaur Nahal, Carlo Selmi, M Eric Gershwin
Systemic lupus erythematosus (SLE) primarily affects women of childbearing age. One of the major changes in SLE focuses on the timing of a successful pregnancy. In the past, pregnancy was strongly discouraged in SLE, especially in the presence of risk factors such as nephritis, use of immunosuppressive therapies, or positivity of specific autoantibodies such as anti-phospholipids and anti-Ro/SSA, La/SSBA. Thanks to our better knowledge on the disease and management, pregnancy success rates in SLE patients have significantly improved care by the a multidisciplinary team which fosters a successful pregnancy with minimal complications for the mother and fetus when the disease is inactive or in remission...
July 27, 2018: Journal of Autoimmunity
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