Dina Villanueva-García, Marcelo Ghezzi, Patricia Mora-Medina, Ismael Hernández-Ávalos, Adriana Olmos-Hernández, Alejandro Casas-Alvarado, Karina Lezama-García, Adriana Domínguez-Oliva, Daniela Rodríguez-González, Miriam Marcet-Rius
Intrapartum asphyxia, fetal hypoxia, and their consequences (e.g., acidosis, hypercapnia, hypoglycemia, and hypothermia) are the main factors related to physio-metabolic imbalances that increase neonatal mortality in piglets, particularly in piglets with low birthweight and low vitality scores. This study aimed to evaluate the effect of three different doses of caffeine (10, 20, and 30 mg/kg) administered orally to 480 newborn piglets with low birthweight and low vitality scores. Blood gas parameters (pH, pO2 , pCO2 , and HCO3 - ), physio-metabolic profile (Ca++ , glucose, and lactate), and the thermal response assessed through infrared thermography in four thermal windows (ocular, auricular, snout, and hindlimb) and rectal temperature were evaluated during the first 24 h of life...
November 12, 2023: Animals: An Open Access Journal From MDPI