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Psoas muscle and sarcopenia

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https://www.readbyqxmd.com/read/30317377/pre-operative-psoas-major-measurement-compared-to-p-possum-as-a-prognostic-indicator-in-over-80s-undergoing-emergency-laparotomy
#1
Gregory Simpson, Alexander Parker, Philip Hopley, Jeremy Wilson, Conor Magee
INTRODUCTION: Emergency laparotomy in patients over the age of 80 is associated with high morbidity and mortality. Accurate risk prediction in this patient population is desirable. Sarcopenia has been shown to be associated with outcome in multiple clinical settings and the psoas major muscle as measured on computed tomography (CT) imaging has been demonstrated as a marker of sarcopenia. We aim to assess the use of psoas major measurement on pre-operative CT as a prognostic indicator in over-80s undergoing emergency laparotomy and compare this measurement to P-POSSUM...
October 13, 2018: European Journal of Trauma and Emergency Surgery: Official Publication of the European Trauma Society
https://www.readbyqxmd.com/read/30316376/a-longer-history-of-hemodialysis-can-lead-to-sarcopenia-in-renal-transplantation-patients
#2
D Takamoto, T Kawahara, T Mochizuki, K Makiyama, J Teranishi, H Uemura
BACKGROUND: Sarcopenia is a condition in which the amount of skeletal muscle decreases. Recent studies have suggested that sarcopenia is a risk factor for the incidence of postoperative complications, longer hospitalization, and a poorer prognosis. In this study, we examined the impact of sarcopenia in association with a history of hemodialysis in renal transplantation patients. METHODS: A total of 157 patients who underwent renal transplantation at Yokohama City University Medical Center (Yokohama, Japan) from 2005 to 2016 were analyzed in this study...
October 2018: Transplantation Proceedings
https://www.readbyqxmd.com/read/30295589/association-between-sarcopenia-and-functional-status-in-liver-transplant-patients
#3
Natasha H Dolgin, Andrew J Smith, Samantha G Harrington, Babak Movahedi, Paulo N A Martins, Adel Bozorgzadeh
OBJECTIVES: A growing body of evidence shows that frailty and functional performance predict liver transplant outcomes. The Organ Procurement and Transplant Network uses the Karnofsky Performance Status scale to adjust for transplant center case mix in assessing quality measures. This study explores the strength of the relationship between Karnofsky Performance Status scores and objective measures of frailty. MATERIALS AND METHODS: This observational study includes 136 adult, first-time liver transplant recipients at UMass Memorial (2006-2015) who had 2 abdominal computed tomography scans available (at ≤ 90 days pretransplant and ≥ 7 days before that)...
October 5, 2018: Experimental and Clinical Transplantation
https://www.readbyqxmd.com/read/30270315/decreased-psoas-muscle-computed-tomography-value-predicts-poor-outcome-in-peripheral-artery-disease
#4
Takayuki Sugai, Tetsu Watanabe, Yoichiro Otaki, Jun Goto, Ken Watanabe, Taku Toshima, Tetsuya Takahashi, Miyuki Yokoyama, Harutoshi Tamura, Satoshi Nishiyama, Takanori Arimoto, Hiroki Takahashi, Tetsuro Shishido, Masafumi Watanabe
BACKGROUND: The prognosis of peripheral artery disease (PAD) and comorbid sarcopenia is poor. Some reports indicate that the computed tomography (CT) value of skeletal muscle, which reflects intramuscular fat deposition as well as skeletal muscle mass, is considered a marker of sarcopenia. However, it remains unclear if skeletal muscle area and CT value are associated with poor outcomes in patients with PAD. Methods and Results: Psoas muscle area and CT value were measured by manual trace at the level of the third lumbar vertebral body in 327 consecutive patients with PAD undergoing endovascular therapy (EVT)...
September 29, 2018: Circulation Journal: Official Journal of the Japanese Circulation Society
https://www.readbyqxmd.com/read/30269421/poor-performance-of-psoas-muscle-index-for-identification-of-patients-with-higher-waitlist-mortality-risk-in-cirrhosis
#5
Maryam Ebadi, Connie W Wang, Jennifer C Lai, Srinivasan Dasarathy, Matthew R Kappus, Michael A Dunn, Elizabeth J Carey, Aldo J Montano-Loza
BACKGROUND: Sarcopenia, characterized by low muscle mass, associates with mortality in patients with cirrhosis. Skeletal muscle area in a single computed tomography image at the level of the third lumbar vertebrate (L3) is a valid representative of whole body muscle mass. Controversy remains regarding applicability of psoas muscle to identify patients at greater risk of mortality. We aimed to determine psoas muscle index (PMI) association with skeletal muscle index (SMI) and to evaluate the capacity of PMI to predict liver transplant waitlist mortality...
September 29, 2018: Journal of Cachexia, Sarcopenia and Muscle
https://www.readbyqxmd.com/read/30180152/pretransplant-sarcopenia-in-patients-with-nash-cirrhosis-does-not-impact-rehospitalization-or-mortality
#6
Elizabeth S Aby, Edward Lee, Satvir S Saggi, Matthew R Viramontes, Jonathan F Grotts, Vatche G Agopian, Ronald W Busuttil, Sammy Saab
BACKGROUND: Malnutrition and muscle wasting are common in patients with end-stage liver disease (ESLD), yet go underdiagnosed. Frequently used indices of nutritional status, such as body mass index, are inflated in patients with ESLD due to a fluid overloaded state. Previous work has demonstrated a strong association between psoas muscle area, a surrogate for sarcopenia, and worse survival following liver transplantation; however, the impact of sarcopenia on post liver transplant outcomes in patients with nonalcoholic steatohepatitis (NASH) cirrhosis has not been evaluated...
September 1, 2018: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/30173713/determining-the-impact-of-sarcopenia-on-postoperative-complications-after-ventral-hernia-repair
#7
Leandra A Barnes, Alexander Y Li, Derrick C Wan, Arash Momeni
BACKGROUND: Postoperative complication following ventral hernia repair (VHR) is a major clinical and financial burden. Preoperative risk assessment is necessary to minimize adverse outcomes following VHR. This study examines the ability of an independent parameter to predict postoperative morbidity following VHR. METHODS: A retrospective analysis of 58 patients who underwent VHR by component separation between January 2009 and December 2013 was performed. Preoperative abdominal CT scans were analyzed to assess sarcopenia...
September 2018: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
https://www.readbyqxmd.com/read/30144881/sarcopenia-is-associated-with-a-greater-incidence-of-delayed-gastric-emptying-following-pancreaticoduodenectomy
#8
James Tankel, Amir Dagan, Elena Vainberg, Elad Boaz, Liel Mogilevsky, Irit Hadas, Petachia Reissman, Menahem Ben Haim
BACKGROUND AND AIMS: Sarcopenia is the degenerative loss of skeletal muscle and has been associated with a variety of post-operative complications. We propose sarcopenia is associated with delayed gastric emptying (DGE) following elective pancreaticoduodenectomy (PD). METHODS: A retrospective analysis of a computerised database maintained in real time of all patients undergoing PD within our hepatobiliary unit was performed. The cross-sectional area of the psoas muscle at the upper border of L3 was calculated and corrected for patient height...
October 2018: Clinical Nutrition ESPEN
https://www.readbyqxmd.com/read/30139644/the-impact-of-preoperative-sarcopenia-defined-based-on-psoas-muscle-area-on-long-term-outcomes-of-heart-valve-surgery
#9
Homare Okamura, Naoyuki Kimura, Keisuke Tanno, Makiko Mieno, Harunobu Matsumoto, Atsushi Yamaguchi, Hideo Adachi
OBJECTIVE: Sarcopenia, age-related loss of muscle mass, is an objective and comprehensive marker of frailty. We aimed to clarify the influence of sarcopenia on the outcomes after heart valve surgery. METHODS: We retrospectively reviewed 1119 patients who underwent valve surgery via median sternotomy at our institution from June 2009 to December 2013. Patients aged <70 years, urgent/emergent cases, and patients without preoperative computed tomography of the abdomen were excluded...
July 27, 2018: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/30124775/opportunistic-measurement-of-skeletal-muscle-size-and-muscle-attenuation-on-computed-tomography-predicts-one-year-mortality-in-medicare-patients
#10
Leon Lenchik, Kristin M Lenoir, Josh Tan, Robert D Boutin, Kathryn E Callahan, Stephen B Kritchevsky, Brian J Wells
Background: Opportunistic assessment of sarcopenia on CT examinations is becoming increasingly common. This study aimed to determine relationships between CT-measured skeletal muscle size and attenuation with one-year risk of mortality in older adults enrolled in a Medicare Shared Savings Program (MSSP). Methods: Relationships between skeletal muscle metrics and all-cause mortality were determined in 436 participants (52% women, mean age 75 years) who had abdominopelvic CT examinations...
August 16, 2018: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
https://www.readbyqxmd.com/read/30122406/sarcopenia-defined-by-a-computed-tomography-estimate-of-the-psoas-muscle-area-does-not-predict-frailty-in-geriatric-trauma-patients
#11
Ashley Mccusker, Muhammad Khan, Narong Kulvatunyou, Muhammad Zeeshan, Joseph V Sakran, Haya Hayek, Terence O'Keeffe, Mohammad Hamidi, Andrew Tang, Bellal Joseph
INTRODUCTION: The aim of our study was to assess the correlation between frailty & sarcopenia and impact of each condition on outcomes in geriatric trauma patients. METHODS: We performed a four-year (2013-2016) secondary analysis of our prospectively maintained frailty database and included all trauma patients age ≥65 y who had CT-abdomen. Trauma-Specific-Frailty-Index (TSFI) was used to calculate frailty. Patients were classified as non-frail or frail. Sarcopenia was defined as the lowest sex-specific-quartile of total-psoas-index (TPI)...
August 3, 2018: American Journal of Surgery
https://www.readbyqxmd.com/read/30048632/albumin-is-predictive-of-1-year-mortality-after-transcatheter-aortic-valve-replacement
#12
Katherine R Hebeler, Heike Baumgarten, John J Squiers, Jordan Wooley, Benjamin D Pollock, Cecile Mahoney, Giovanni Filardo, Brian Lima, J Michael DiMaio
BACKGROUND: A validated model for predicting 1-year outcomes after transcatheter aortic valve replacement (TAVR) does not exist. TAVR-specific risk models may benefit from frailty markers, and sarcopenia may represent an objective frailty marker. This study assessed the predictive ability of sarcopenia and frailty markers on 1-year mortality after TAVR. METHODS: We evaluated 470 patients undergoing TAVR at a single center. Frailty was assessed using four markers: gait speed, hand grip strength, serum albumin, and Katz activities of daily living...
July 23, 2018: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/30040184/relationship-between-total-body-protein-and-cross-sectional-skeletal-muscle-area-in-liver-cirrhosis-is-influenced-by-overhydration
#13
Cameron I Wells, John L McCall, Lindsay D Plank
Sarcopenia as defined by reduced skeletal muscle area (SMA) on cross-sectional abdominal imaging has been proposed as an objective measure of malnutrition, and is associated with both waitlist mortality and post-transplant complications in patients with cirrhosis. SMA, however, has never been validated against the gold-standard measurement of total body protein (TBP) by in vivo neutron activation analysis (IVNAA). Furthermore, overhydration is common in cirrhosis and its effect on muscle area measurement remains unknown...
July 24, 2018: Liver Transplantation
https://www.readbyqxmd.com/read/30014202/association-of-paraspinal-muscle-water-fat-mri-based-measurements-with-isometric-strength-measurements
#14
Sarah Schlaeger, Stephanie Inhuber, Alexander Rohrmeier, Michael Dieckmeyer, Friedemann Freitag, Elisabeth Klupp, Dominik Weidlich, Georg Feuerriegel, Florian Kreuzpointner, Ansgar Schwirtz, Ernst J Rummeny, Claus Zimmer, Jan S Kirschke, Dimitrios C Karampinos, Thomas Baum
OBJECTIVES: Chemical shift encoding-based water-fat MRI derived proton density fat fraction (PDFF) of the paraspinal muscles has been emerging as a surrogate marker in subjects with sarcopenia, lower back pain, injuries and neuromuscular disorders. The present study investigates the performance of paraspinal muscle PDFF and cross-sectional area (CSA) in predicting isometric muscle strength. METHODS: Twenty-six healthy subjects (57.7% women; age: 30 ± 6 years) underwent 3T axial MRI of the lumbar spine using a six-echo 3D spoiled gradient echo sequence for chemical shift encoding-based water-fat separation...
July 16, 2018: European Radiology
https://www.readbyqxmd.com/read/30005446/ratio-between-estimated-glomerular-filtration-rates-of-creatinine-and-cystatin-c-predicts-overall-survival-in-patients-with-hepatocellular-carcinoma
#15
Yasuyuki Tamai, Motoh Iwasa, Yuya Kawasaki, Naohiko Yoshizawa, Suguru Ogura, Ryosuke Sugimoto, Akiko Eguchi, Norihiko Yamamoto, Kazushi Sugimoto, Hiroshi Hasegawa, Yoshiyuki Takei
AIM: Hepatocellular carcinoma (HCC) patients with sarcopenia have a poor survival, but there are no predictive markers for survival relating to muscle mass and liver function. Therefore, we investigated whether the ratio between estimated glomerular filtration rates of serum creatinine (Scre) and serum cystatin C (Scys) (eGFRcre/eGFRcys) can be used as a predictive marker of survival in HCC patients. METHODS: First, the correlation between Scre/Scys ratio and muscle mass was examined in 50 patients with chronic liver disease...
July 13, 2018: Hepatology Research: the Official Journal of the Japan Society of Hepatology
https://www.readbyqxmd.com/read/29991895/muscle-fat-infiltration-assessed-by-total-psoas-density-on-computed-tomography-predicts-mortality-in-cirrhosis
#16
Maria Kalafateli, Andreas Karatzas, Georgios Tsiaoussis, Efstratios Koutroumpakis, Paraskevi Tselekouni, Nikolaos Koukias, Christos Konstantakis, Stelios Assimakopoulos, Charalambos Gogos, Konstantinos Thomopoulos, Christina Kalogeropoulou, Christos Triantos
Background: Ongoing evidence suggests that sarcopenia adversely affects outcomes in cirrhosis. The aim of this study was to evaluate muscle fat infiltration as a component of sarcopenia and its prognostic value in this setting. Methods: In 98 consecutive patients with cirrhosis, muscle density was measured during a computed tomography scan at the level of the fourth to fifth lumbar (L4) vertebrae. Univariate and multivariate Cox regression analysis was used to determine predictors of survival...
July 2018: Annals of Gastroenterology: Quarterly Publication of the Hellenic Society of Gastroenterology
https://www.readbyqxmd.com/read/29805792/preoperative-evaluation-of-skeletal-muscle-mass-in-the-risk-assessment-for-the-short-term-outcome-of-elderly-colorectal-cancer-patients-undergoing-colectomy
#17
Hiroshi Tamagawa, Toru Aoyama, Kenta Iguchi, Hirohito Fujikawa, Sho Sawazaki, Tsutomu Sato, Hiroyuki Musiake, Takashi Oshima, Norio Yukawa, Yasushi Rino, Munetaka Masuda
The prevalence of colorectal cancer in the elderly population is increasing; therefore, surgical interventions with a risk of potential complications are more frequently performed. The aim of the present study was to elucidate whether sarcopenia has a clinical impact on short-term outcomes, such as morbidity and hospital stay after surgery, in elderly patients with colorectal cancer. A total of 82 elderly patients undergoing colectomy for colorectal cancer between January 2011 and December 2015 in our institute were included in the study, and skeletal muscle mass was measured as total psoas area at the level of the third lumbar vertebra (L3) using enhanced computed tomography scans...
June 2018: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/29789798/the-relation-between-sarcopenia-and-mortality-in-patients-at-intensive-care-unit
#18
Mehmet Toptas, Mazhar Yalcin, İbrahim Akkoc, Eren Demir, Cagatay Metin, Yildiray Savas, Muhsin Kalyoncuoglu, Mehmet Mustafa Can
Background and Aim: Psoas muscle area (PMA) can reflect the status of skeletal muscle in the whole body. It has been also reported that decreased PMA was associated with postoperative mortality or morbidity after several surgical procedures. In this study, we aimed to investigate the relation between PMA and mortality in all age groups in intensive care unit (UNIT). Materials and Method: The study consists of 362 consecutive patients. The demographic characteristics of patients, indications for ICU hospitalization, laboratory parameters, and clinical parameters consist of mortality and length of stay, and surgery history was obtained from intensive care archive records...
2018: BioMed Research International
https://www.readbyqxmd.com/read/29761898/clinical-impact-of-muscle-quantity-and-quality-in-colorectal-cancer-patients-a-propensity-score-matching-analysis
#19
Yoshinaga Okugawa, Yuji Toiyama, Akira Yamamoto, Tsunehiko Shigemori, Chengzeng Yin, Aya Narumi, Yusuke Omura, Shozo Ide, Takahito Kitajima, Hiroyuki Fujikawa, Hiromi Yasuda, Junichiro Hiro, Shigeyuki Yoshiyama, Minako Kobayashi, Toshimitsu Araki, Donald C McMillan, Chikao Miki, Masato Kusunoki
BACKGROUND: Sarcopenia is defined as the loss of skeletal muscle mass, accompanied by decreased muscle strength, and consists of myopenia and myosteatosis. Recent evidence has suggested the predictive value of sarcopenia for the risk of perioperative and oncological outcomes in various malignancies. The aim of this study was to clarify the clinical impact of myopenia and myosteatosis in colorectal cancer (CRC) patients. METHODS: We analyzed the preoperative psoas muscle mass index and intramuscular adipose tissue content using preoperative computed tomography images from 308 CRC patients using statistical methods...
May 15, 2018: JPEN. Journal of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/29751134/sarcopenia-in-resected-nsclc-effect-on-postoperative-outcomes
#20
Ryota Nakamura, Yoshihisa Inage, Rika Tobita, Satoshi Yoneyama, Takeshi Numata, Kyoko Ota, Hidetoshi Yanai, Takeo Endo, Yukinori Inadome, Shingo Sakashita, Hiroaki Satoh, Kenji Yuzawa, Toru Terashima
INTRODUCTION: Skeletal muscle depletion, referred to as sarcopenia, has recently been identified as a risk factor for poor outcomes in various malignancies. However, the prognostic significance of sarcopenia in patients with NSCLC after surgery has not been adequately determined. This study investigated the impact of sarcopenia in patients undergoing pulmonary resection for lung cancer. METHODS: This retrospective study consisted of 328 patients with pathologically confirmed NSCLC who underwent curative resection between January 2005 and April 2017...
July 2018: Journal of Thoracic Oncology
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