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In my mind

Anna Kipnis
More than ever, science is in the unenviable position of competing for the hearts and minds of the public against utterly false accounts of our world. These false accounts are often deeply spiritual, poetic, sublime - despite being false, they can leave a mark on the human imagination. It is difficult to convey scientific research in a way that leaves the audience with a comparable sense of awe or a personal connection to the subject matter. This is an area where games as a cultural form can offer some assistance and insight...
July 20, 2018: Integrative and Comparative Biology
S C Barclay
Since 2015 the body known as NHS Improvement has published, and this year updated, its list of never events - defined as 'serious incidents that are entirely preventable because guidance or safety recommendations providing strong systemic protective barriers are available at a national level.' How this is interpreted, however, especially in dental terms, has been very poorly managed in my opinion, leading to the potential for increased risk of such events happening and raising anxiety levels among many colleagues, especially the newly qualified, and responses to them both at a local and national level potentially give the lie to the no-blame culture purported to exist within healthcare in the UK...
July 27, 2018: British Dental Journal
Neil MacRitchie, Pasquale Maffia
The hallmark features of atherosclerosis include accumulation of low-density lipoprotein (LDL) carrying cholesterol in the vessel wall, formation of lipid-laden foam cells, and the creation of a pro-inflammatory microenvironment. To date, no effective treatments are clinically available for increasing cholesterol efflux from vascular macrophages and inducing reverse cholesterol transport (RCT). In an article published recently in Clinical Science (vol 132, issue 6, 1199-1213), Zhang and colleagues identified the extracellular matrix protein mindin/spondin 2 as a positive regulator of atherosclerosis...
July 31, 2018: Clinical Science (1979-)
Pablo Buitron de la Vega, Christopher Coe, Michael K Paasche-Orlow, Jack A Clark, Katherine Waite, Maria Jose Sanchez, Emily Armstrong, Barbara G Bokhour
BACKGROUND: A patient's self-management of chronic disease is influenced in part by their explanatory model of illness (EMI) and daily lived experiences (DLE). Unfortunately, assessing patient's EMI and using this information to engage patients in chronic illness self-management continues to be a challenge. OBJECTIVE: "Health mind mapping" (HMM) is a novel process that captures a patient's EMI and DLE through the use of a graphic representation of ideas...
July 10, 2018: Journal of General Internal Medicine
Sofie Boldsen
Sensorimotor research is currently challenging the dominant understanding of autism as a deficit in the cognitive ability to 'mindread'. This marks an emerging shift in autism research from a focus on the structure and processes of the mind to a focus on autistic behavior as grounded in the body. Contemporary researchers in sensorimotor differences in autism call for a reconciliation between the scientific understanding of autism and the first-person experience of autistic individuals. I argue that fulfilling this ambition requires a phenomenological understanding of the body as it presents itself in ordinary experience, namely as the subject of experience rather than a physical object...
June 18, 2018: Culture, Medicine and Psychiatry
Alison Searle
The relationship between pain as a physical and emotional experience and the concept of suffering as an essential aspect of sanctification for faithful believers was a paradoxical and pressing theological and phenomenological issue for puritan and non-conformist communities in 17th-century England. Pain allows the paradox of non-conformists' valorisation and suppression of corporeality to be explored due to its simultaneous impact on the mind and body and its tendency to leak across boundaries separating an individual believer from other members of their family or faith community...
June 2018: Medical Humanities
Curt Tribble Md
To paraphrase the lyrics of a song by Matchbox Twenty ("It's 3AM, I must be lonely"), it's 3 AM, I must be on a Lear jet. We're heading out to get a pair of lungs for a transplant. It's pitch black out tonight, and there's small rain falling. At least it's not ice or snow, which we've heard is falling to the north of us. I am glad that we'll be heading south on this run. These organ procurement runs tend to violate one of the basic safety rules of flying, which is to avoid, whenever possible, being required to fly...
June 8, 2018: Heart Surgery Forum
Patrizia Fattoretti, Marco Malavolta, Paolo Fabbietti, Roberta Papa, Robertina Giacconi, Laura Costarelli, Roberta Galeazzi, Cristina Paoloni, Demetrio Postacchini, Fabrizia Lattanzio, Cinzia Giuli
BACKGROUND: Biomarkers of oxidative stress have been associated with cognitive status in humans and have been proposed to guide prognosis/treatment in Alzheimer's disease (AD) and mild cognitive impairment (MCI). OBJECTIVE: The aim of this study was to compare oxidative stress status in the plasma of mild-moderate AD, MCI, and healthy elderly with normal cognition (HE) undergoing a non-pharmacological intervention including multi-modal cognitive training ("My Mind Project")...
2018: Journal of Alzheimer's Disease: JAD
Nicole Pope, Mary Tallon, Gavin Leslie, Sally Wilson
PURPOSE: Pain management within emergency departments (ED) remains challenging. Given that unrelieved pain in children is linked to a number of negative physiological and psychological consequences, optimal management of children's pain is paramount. Many studies exploring children's pain have adopted quantitative methods or sought the perspectives of adults. Compared to adults, studies examining children's views on pain and pain management are limited. This study aimed to explore children's pain experiences, their perception of pain management and expectations of the role of the nurse...
May 23, 2018: Journal for Specialists in Pediatric Nursing: JSPN
Timothy P Daaleman
For several months I have been trying to tag a greyness that has shaded my doctoring. I was not burned out but uncovered the desert experience of mind and soul known as acedia, which is called the noonday demon because it vexes those in the mid-stages of life. Grappling with the noonday demon has upended all of my assumptions about the workings of hope in the practice of medicine. For me, hope is no longer the anticipation of a positive outcome, or the warm feeling associated with the validation of a correct diagnosis, or the conclusion of successful treatment...
May 2018: Annals of Family Medicine
Karl Friston
Is self-consciousness necessary for consciousness? The answer is yes. So there you have it-the answer is yes. This was my response to a question I was asked to address in a recent AEON piece ( What follows is based upon the notes for that essay, with a special focus on self-organization, self-evidencing and self-modeling. I will try to substantiate my (polemic) answer from the perspective of a physicist. In brief, the argument goes as follows: if we want to talk about creatures, like ourselves, then we have to identify the characteristic behaviors they must exhibit...
2018: Frontiers in Psychology
Dean P McKenzie, Marina G Downing, Jennie L Ponsford
BACKGROUND: Anxiety and depression are common problems following traumatic brain injury (TBI), warranting routine screening. Self-report rating scales including the Hospital Anxiety and Depression Scale (HADS) are associated with depression and anxiety diagnoses in individuals with TBI. The relationship between individual HADS symptoms and structured clinical interview methods (SCID) requires further investigation, particularly in regard to identifying a small number of key items that can potentially be recognised by clinicians and carers of individuals with TBI...
August 15, 2018: Journal of Affective Disorders
Katrin Fabian, Josiah Fannoh, George G Washington, Wilfred B Geninyan, Bethuel Nyachienga, Garmai Cyrus, Joyce N Hallowanger, Jason Beste, Deepa Rao, Bradley H Wagenaar
The integration of culturally salient idioms of distress into mental healthcare delivery is essential for effective screening, diagnosis, and treatment. This study systematically explored idioms, explanatory models, and conceptualizations in Maryland County, Liberia to develop a culturally-resonant screening tool for mental distress. We employed a sequential mixed-methods process of: (1) free-lists and semi-structured interviews (n = 20); patient chart reviews (n = 315); (2) pile-sort exercises, (n = 31); and (3) confirmatory focus group discussions (FGDs); (n = 3) from June to December 2017...
May 4, 2018: Culture, Medicine and Psychiatry
Madalina Vlasceanu, Rae Drach, Alin Coman
The mind is a prediction machine. In most situations, it has expectations as to what might happen. But when predictions are invalidated by experience (i.e., prediction errors), the memories that generate these predictions are suppressed. Here, we explore the effect of prediction error on listeners' memories following social interaction. We find that listening to a speaker recounting experiences similar to one's own triggers prediction errors on the part of the listener that lead to the suppression of her memories...
May 3, 2018: Psychonomic Bulletin & Review
David J Bartlett, Daniel S Childs, Carmen Radecki Breitkopf, Megan E Grudem, Jessica L Mitchell, Sherry A Looker, Jennifer L Ridgeway, Jennifer L Lee, Joseph H Butterfield, S John Weroha, Aminah Jatoi
OBJECTIVE: A growing number of cancer antineoplastic agents can cause life-threatening acute infusion reactions. Because previous studies have not studied these reactions from the perspective of patients, this study was undertaken with that objective in mind. METHODS: Patients who had an acute infusion reaction were interviewed based on the Leventhal model. Once saturation of content was achieved, interviews were transcribed and analyzed with qualitative methodology...
January 1, 2018: American Journal of Hospice & Palliative Care
Xavier Monnet, Jean-Louis Teboul
Many efforts have been made to predict, before giving fluid, whether it will increase cardiac output. Nevertheless, after fluid administration, it is also essential to assess the therapeutic efficacy and to look for possible adverse effects. Like for any drug, this step should not be missed. Basically, volume expansion is aimed at improving tissue oxygenation and organ function. To assess this final result, clinical signs are often unhelpful. The increase in urine output in case of acute kidney injury is a poor marker of the kidney perfusion improvement...
April 24, 2018: Annals of Intensive Care
Florian Schmidsberger, Henriette Löffler-Stastka
BACKGROUND: The current philosophical debate on empathy entails accounts of theory of mind and simulation as well as a phenomenological opposition. The first focuses on a detached observation of others from a 3rd person perspective and formulates the common claim that there is no direct access to the mental and emotional life of others, only simulation or analogy can grant access to the emotions and behaviour of others. The philosophical respectively phenomenological account of Fuchs instead opposes by focusing personal interaction within a 1st or 2nd person perspective claiming that the emotions of others are experienceable through bodily expression and bodily resonance...
April 5, 2018: BMC Medical Education
Gary Fuller
In the philosophy of mind and psychology, a central question since the 1960s has been that of how to give a philosophically adequate formulation of mind-body physicalism. A large quantity of work on the topic has been done in the interim. There have been, and continue to be, extensive discussions of the ideas of physicalism, identity, functionalism, realization, and constitution. My aim in this paper is a modest one: it is to get clearer about these ideas and some of their interrelations. After providing some background and history, I shall focus on two related topics: the distinction between a functional property and a structural one and the dispute over whether a realization account of the mental-physical relation provides a better physicalist account than a constitutional account...
April 2018: Studies in History and Philosophy of Science
Sherman Silber
A recent series of articles and reviews published in Fertility and Sterility have rekindled the more than half century debate on varicocelectomy. Every one of these articles favored strongly the repair of varicocele for male infertility. Since my review paper on this issue in 2001, published in Human Reproduction Update, and since advent of ICSI in 1993, I had thought that most reproductive physicians felt negatively about the benefit of varicocelectomy. However, more recent urological papers are causing this negative view to be re-evaluated...
June 2018: Journal of Assisted Reproduction and Genetics
Svend Brinkmann
Much theorizing in psychology and related disciplines begins with a given model of the mind that is then applied in research projects to study concrete phenomena. Sometimes psychological research can be theory-driven in quite an explicit way, approaching the logic of the hypothetico-deductive method. Others reject this and prefer to work inductively, and, in the extreme case of positivism, perhaps try to avoid theorizing altogether. In this article I shall suggest another way to think of the relationship between psychological theories and psychological phenomena...
June 2018: Integrative Psychological & Behavioral Science
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