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Manual diagnosis

Annalisa Nicoletti, Nicola Di Girolamo, Ulrich Zeyen, Paolo Selleri, Marco Masi, Paolo Fonti
PURPOSE: Cecal appendix is the terminal part of cecum and is characteristic of rabbit, among domestic animals. The purpose of this work is to evaluate its morphology upon ultrasound. METHODS: A prospective study was planned for the duration of approximately 1 year. Rabbits presented in the study period for abdominal ultrasound with no clinically evident alterations of the gastrointestinal tract were eligible for inclusion in the study. Abdominal ultrasound was performed under manual restrain with a high frequency linear probe (8-18 MHz)...
August 10, 2018: Journal of Ultrasound
Karem D Marcomini, Eduardo F C Fleury, Vilmar M Oliveira, Antonio A O Carneiro, Homero Schiabel, Robert M Nishikawa
Purpose: Evaluation of the performance of a computer-aided diagnosis (CAD) system based on the quantified color distribution in strain elastography imaging to evaluate the malignancy of breast tumors. Methods: The database consisted of 31 malignant and 52 benign lesions. A radiologist who was blinded to the diagnosis performed the visual analysis of the lesions. After six months with no eye contact on the breast images, the same radiologist and other two radiologists manually drew the contour of the lesions in B-mode ultrasound, which was masked in the elastography image...
August 9, 2018: Bioengineering
Qi Feng, Yuanjun Chen, Zhengluan Liao, Hongyang Jiang, Dewang Mao, Mei Wang, Enyan Yu, Zhongxiang Ding
Background: Alzheimer's disease (AD) is a progressive neurodegenerative disease that causes the decline of some cognitive impairments. The present study aimed to identify the corpus callosum (CC) radiomic features related to the diagnosis of AD and build and evaluate a classification model. Methods: Radiomics analysis was applied to the three-dimensional T1-weighted magnetization-prepared rapid gradient echo (MPRAGE) images of 78 patients with AD and 44 healthy controls (HC). The CC, in each subject, was segmented manually and 385 features were obtained after calculation...
2018: Frontiers in Neurology
C E McCafferty, D Abi-Hanna, M J Aghajani, G T Micali, I Lockart, K Vickery, I B Gosbell, S O Jensen
BACKGROUND AND AIM(S): Endoscopic procedures are vital to gastrointestinal disease diagnosis and management, but risk infection transmission. In Australia, endoscopes undergo monthly-to-quarterly microbiological testing, to prevent patient infection. Endoscopes are used more frequently, meaning contamination may not be detected by this surveillance before infection transmission occurs. This study aimed to evaluate the use of adenosine triphosphate (ATP) measurement, alongside standard microbiological cultures in detecting endoscope contamination before high-level disinfection...
August 6, 2018: Journal of Hospital Infection
Bahar Khorram, Mehran Yazdi
Image segmentation is considered as one of the most fundamental tasks in image processing applications. Segmentation of magnetic resonance (MR) brain images is also an important pre-processing step, since many neural disorders are associated with brain's volume changes. As a result, brain image segmentation can be considered as an essential measure toward automated diagnosis or interpretation of regions of interest, which can help surgical planning, analyzing changes of brain's volume in different tissue types, and identifying neural disorders...
August 8, 2018: Journal of Digital Imaging: the Official Journal of the Society for Computer Applications in Radiology
Joseph T Giacino, Douglas I Katz, Nicholas D Schiff, John Whyte, Eric J Ashman, Stephen Ashwal, Richard Barbano, Flora M Hammond, Steven Laureys, Geoffrey S F Ling, Risa Nakase-Richardson, Ronald T Seel, Stuart Yablon, Thomas S D Getchius, Gary S Gronseth, Melissa J Armstrong
OBJECTIVE: To update the 1995 American Academy of Neurology (AAN) practice parameter on persistent vegetative state and the 2002 case definition for the minimally conscious state (MCS) by reviewing the literature on the diagnosis, natural history, prognosis, and treatment of disorders of consciousness lasting at least 28 days. METHODS: Articles were classified per the AAN evidence-based classification system. Evidence synthesis occurred through a modified Grading of Recommendations Assessment, Development and Evaluation process...
August 8, 2018: Neurology
Leticia A Barajas-Nava, Andrea Sandoval-Campos, Karen Aguirre-Raya
Introducción: El ensayo clínico es la manera más rigurosa de conducir los experimentos en seres humanos. Desde su introducción en investigación biomédica se han implementado cambios en el modo de establecer las bases para el diagnóstico, pronóstico y la terapéutica en la práctica clínica. Se han realizado estudios para identificar los ensayos clínicos publicados en diferentes áreas médicas, pero hasta el momento ninguno había identificado los ensayos clínicos publicados en el Boletín Médico del Hospital Infantil de México (BMHIM)...
2018: Boletín Médico del Hospital Infantil de México
Yuxin Lin, Wentao Wu, Zhandong Sun, Li Shen, Bairong Shen
MicroRNAs (miRNAs) are small non-coding RNAs with the potential as biomarkers for disease diagnosis, prognosis and therapy. In the era of big data and biomedical informatics, computer-aided biomarker discovery has become the current frontier. However, most of the computational models are highly dependent on specific prior knowledge and training-testing procedures, very few are mechanism-guided or evidence-based. To the best of our knowledge, untill now no general rules have been uncovered and applied to miRNA biomarker screening...
August 6, 2018: RNA Biology
Tharshanah Thayabaranathan, Nadine E Andrew, Monique F Kilkenny, Rene Stolwyk, Amanda G Thrift, Rohan Grimley, Trisha Johnston, Vijaya Sundararajan, Natasha A Lannin, Dominique A Cadilhac
PURPOSE: Approximately 30-50% of survivors experience problems with anxiety or depression post-stroke. It is important to understand the factors associated with post-stroke anxiety or depression to identify effective interventions. METHODS: Patient-level data from the Australian Stroke Clinical Registry (years 2009-2013), from participating hospitals in Queensland (n = 23), were linked with Queensland Hospital Emergency and Admission datasets. Self-reported anxiety or depression was assessed using the EQ-5D-3L, obtained at 90-180 days post-stroke...
August 4, 2018: Quality of Life Research
Matthew C Coombs, Daniel J Bonthius, Xingju Nie, Michael K Lecholop, Martin B Steed, Hai Yao
PURPOSE: Accurate description of the temporomandibular size and shape (morphometry) is critical for clinical diagnosis and surgical planning and the design and development of regenerative scaffolds and prosthetic devices and to model the temporomandibular loading environment. The study objective was to determine the 3-dimensional morphometry of the temporomandibular joint (TMJ) condyle and articular disc using cone-beam computed tomography (CBCT), magnetic resonance imaging (MRI), and physical measurements of the same joints using a repeated measures design and to determine the effect of the measurement technique on temporomandibular size and shape...
July 10, 2018: Journal of Oral and Maxillofacial Surgery
Amir M Tahmasebi, Henghui Zhu, Gabriel Mankovich, Peter Prinsen, Prescott Klassen, Sam Pilato, Rob van Ommering, Pritesh Patel, Martin L Gunn, Paul Chang
In today's radiology workflow, free-text reporting is established as the most common medium to capture, store, and communicate clinical information. Radiologists routinely refer to prior radiology reports of a patient to recall critical information for new diagnosis, which is quite tedious, time consuming, and prone to human error. Automatic structuring of report content is desired to facilitate such inquiry of information. In this work, we propose an unsupervised machine learning approach to automatically structure radiology reports by detecting and normalizing anatomical phrases based on the Systematized Nomenclature of Medicine-Clinical Terms (SNOMED CT) ontology...
August 3, 2018: Journal of Digital Imaging: the Official Journal of the Society for Computer Applications in Radiology
Mariana Santos, Eva Osório, Sarah Finnegan, Matt Clarkson, Sertório Timóteo, Isabel Brandão, António Roma-Torres, Nick C Fox, António J Bastos-Leite
We aimed to determine whether variation in the body mass index (BMI)-a marker of anorexia nervosa (AN) severity-is associated with brain volume changes longitudinally estimated using registration-based methods on serial high-resolution T1-weighted magnetic resonance images (MRI). Fifteen female patients (mean age = 21 years; standard deviation [SD] = 5.7; range: 15-33 years) with the diagnosis of AN of the restricting type (AN-r)-according to the Diagnostic and Statistic Manual of Mental Disorders, 5th edition criteria-underwent T1-weighted MRI at baseline and after a mean follow-up period of 11 months (SD = 6...
July 9, 2018: Psychiatry research. Neuroimaging
Melinda Randall, Kristine J Egberts, Aarti Samtani, Rob Jpm Scholten, Lotty Hooft, Nuala Livingstone, Katy Sterling-Levis, Susan Woolfenden, Katrina Williams
BACKGROUND: Autism spectrum disorder (ASD) is a behaviourally diagnosed condition. It is defined by impairments in social communication or the presence of restricted or repetitive behaviours, or both. Diagnosis is made according to existing classification systems. In recent years, especially following publication of the Diagnostic and Statistical Manual of Mental Disorders - Fifth Edition (DSM-5; APA 2013), children are given the diagnosis of ASD, rather than subclassifications of the spectrum such as autistic disorder, Asperger syndrome, or pervasive developmental disorder - not otherwise specified...
July 24, 2018: Cochrane Database of Systematic Reviews
Erik Kudela, Jozef Visnovsky, Tomas Balharek, Anna Farkasova, Pavol Zubor, Lukas Plank, Jan Danko
PURPOSE: The aim of this study was to evaluate and correlate the amplification of chromosomal regions 3q26 and 5p15 in different cytological and histological subgroups of patients and to compare the sensitivity and specificity of amplification tests with cytology, colposcopy and HPV status. METHODS: The work was conducted at the Department of Obstetrics and Gynaecology in cooperation with the Institute of Pathological Anatomy, JFM CU in Martin and UNM during years 2013-2016...
August 2018: Annals of Diagnostic Pathology
Michelle Jackman, Iona Novak, Natasha Lannin, Elspeth Froude, Laura Miller, Claire Galea
BACKGROUND: Functional hand splinting is a common therapeutic intervention for children with neurological conditions. The aim of this study was to investigate the effectiveness of the Cognitive Orientation to daily Occupational Performance (CO-OP) approach over and above conventional functional hand splinting, and in combination with splinting, for children with cerebral palsy or brain injury. METHODS: A multisite, assessor-blinded, parallel, randomized controlled trial was conducted in Australia...
July 31, 2018: BMC Pediatrics
Michael P Wendel, Kelsey L Shnaekel, Everett F Magann
Importance: Uterine inversion is frequently accompanied by postpartum hemorrhage and hypovolemic shock. Morbidity and mortality occur in as many as 41% of cases. Prompt recognition and management are of utmost importance. Objective: The aim of this review is to describe risk factors, clinical and radiographic diagnostic criteria, and management of this rare but potentially life-threatening complication of pregnancy. Evidence Acquisition: A PubMed, Web of Science, and CINAHL search was undertaken with no limitations on the number of years searched...
July 2018: Obstetrical & Gynecological Survey
Robin L Gabriels, Zhaoxing Pan, Noémie A Guérin, Briar Dechant, Gary Mesibov
This paper presents 6-month follow-up data of 44% ( N = 64/116) of participants (ages 6-16 years) with a diagnosis of autism spectrum disorder, who participated in a previously-published randomized controlled trial of therapeutic horseback riding (THR) compared to a no-horse contact active control. The objective of this study was to examine whether significant improvements of irritability, hyperactivity, social, and communication behaviors observed in participants randomized to receive a 10-week manual-based THR intervention were sustained 6 months after the intervention conclusion...
2018: Frontiers in Veterinary Science
Samuel D James, Alexander T Hawkins, Amosy E M'Koma
Adenocarcinoma that occurs at the ileostomy site after proctocolectomy (TPC) with an end ileostomy for ulcerative colitis (UC) and/or familial adenomatous polyposis (FAP) is a late and uncommon complication. To ascertain the rate of adenocarcinoma at the empirical ileostomy site following TPC, a review of the literature was conducted. PubMed, MEDLINE, the Cumulative Index of Nursing and Allied Health Literature, EMBASE, Google search engine, and the Cochrane Database were investigated for research published between January 1975 and December 2016...
June 2018: Ostomy/wound Management
Wieland A Worthoff, Aliaksandra Shymanskaya, N Jon Shah
PURPOSE: Sodium imaging delivers valuable information about in vivo metabolism and pathophysiology. Image quantification can benefit the diagnosis and characterization of existing pathologies and the clinical course of a disease. An enhanced SISTINA sequence is proposed for sodium imaging and for the estimation of sodium tissue parameters for a 2-compartment model of the brain, such as relaxation times in intracellular space and tissue, intracellular volume fraction, and intracellular molar fraction...
July 29, 2018: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
Joana Ribeiro, Olinda Rebelo, Ana Fernández-Marmiesse, Luís Negrão
A group of heterogeneous muscle diseases are caused by dystrophin gene ( DMD ) mutations. We hereby present a male patient with a diagnosis of symptomatic dilated cardiomyopathy at 44 years-old who developed, soon after, weakness of distal right upper limb. At the age of 58, neurological examination revealed severe atrophy of right thenar muscles, flexion contractures on the right elbow, wrist and fingers, bilateral calf hypertrophy, myotatic areflexia in the upper limbs and hyporeflexia in the lower limbs...
June 2018: Acta Myologica: Myopathies and Cardiomyopathies: Official Journal of the Mediterranean Society of Myology
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