Eliah G Overbey, Krista Ryon, JangKeun Kim, Braden Tierney, Remi Klotz, Veronica Ortiz, Sean Mullane, Julian C Schmidt, Matthew MacKay, Namita Damle, Deena Najjar, Irina Matei, Laura Patras, J Sebastian Garcia Medina, Ashley Kleinman, Jeremy Wain Hirschberg, Jacqueline Proszynski, S Anand Narayanan, Caleb M Schmidt, Evan E Afshin, Lucinda Innes, Mateo Mejia Saldarriaga, Michael A Schmidt, Richard D Granstein, Bader Shirah, Min Yu, David Lyden, Jaime Mateus, Christopher E Mason
The SpaceX Inspiration4 mission provided a unique opportunity to study the impact of spaceflight on the human body. Biospecimen samples were collected from the crew at different stages of the mission, including before (L-92, L-44, L-3 days), during (FD1, FD2, FD3), and after (R+1, R+45, R+82, R+194 days) spaceflight, creating a longitudinal sample set. The collection process included samples such as venous blood, capillary dried blood spot cards, saliva, urine, stool, body swabs, capsule swabs, SpaceX Dragon capsule HEPA filter, and skin biopsies, which were processed to obtain aliquots of serum, plasma, extracellular vesicles, and peripheral blood mononuclear cells...
May 2, 2023: bioRxiv