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https://www.readbyqxmd.com/read/29144300/enhancing-dewaterability-of-waste-activated-sludge-by-combined-oxidative-conditioning-process-with-zero-valent-iron-and-peroxymonosulfate
#1
Xu Zhou, Wenbiao Jin, Hongyi Chen, Chuan Chen, Songfang Han, Renjie Tu, Wei Wei, Shu-Hong Gao, Guo-Jun Xie, Qilin Wang
The enhancement of sludge dewaterability is of great importance for facilitating the sludge disposal during the operation of wastewater treatment plants. In this study, a novel oxidative conditioning approach was applied to enhance the dewaterability of waste activated sludge by the combination of zero-valent iron (ZVI) and peroxymonosulfate (PMS). It was found that the dewaterability of sludge was significantly improved after the addition of ZVI (0-4 g/g TSS) (TSS: total suspended solids) and PMS (0-1 g/g TSS)...
November 2017: Water Science and Technology: a Journal of the International Association on Water Pollution Research
https://www.readbyqxmd.com/read/29142413/antiurolithiatic-potential-of-neeri-against-calcium-oxalate-stones-by-crystallization-inhibition-free-radicals-scavenging-and-nrk-52e-cell-protection-from-oxalate-injury
#2
Parveen Kumar Goyal, Santosh Kumar Verma, Anil Kumar Sharma
Background: Neeri is a well-established polyherbal formulation prescribed for renal stones by the physicians but has not been experimentally evaluated for its antiurolithiatic potential using cell-lines. Objective: This study is aimed to scientifically substantiate the antiurolithiatic effect of Neeri extract (NRE) through calcium oxalate (CaOx) crystallization inhibition, scavenging of free radicals, and protection of renal tubular epithelial NRK-52E cells from oxalate-induced injury...
October 2017: Pharmacognosy Magazine
https://www.readbyqxmd.com/read/29142401/phytochemical-compositions-and-in-vitro-assessments-of-antioxidant-and-antidiabetic-potentials-of-fractions-from-ehretia-cymosa-thonn
#3
Akintayo Ogundajo, Anofi Tom Ashafa
Background: Ehretia cymosa Thonn. is a popular medicinal plant used in different parts of West Africa for the treatment of various ailments including diabetes mellitus. Objective: The current study investigates bioactive constituents and in vitro antioxidant and antidiabetic potentials of fractions from extract of E. cymosa. Materials and Methods: Phytochemical investigation and antioxidant assays were carried out using standard procedures...
October 2017: Pharmacognosy Magazine
https://www.readbyqxmd.com/read/29141822/epidemiological-and-clinical-characteristics-of-multiple-sclerosis-in-paediatric-population-in-slovenia-a-descriptive-nation-wide-study
#4
Neli Bizjak, Damjan Osredkar, Mirjana Perković Benedik, Saša Šega Jazbec
BACKGROUND: Although multiple sclerosis usually affects young adults, paediatric-onset multiple sclerosis (pMS) is increasingly recognized in the past ten years. The aim of the present study was to evaluate the incidence of pMS in Slovenia and to characterize the clinical, laboratory and neuroradiological characteristics of pMS at the disease onset. METHODS: We performed a national retrospective descriptive study including all patients diagnosed with pMS between January 1992 and June 2017...
November 2017: Multiple Sclerosis and related Disorders
https://www.readbyqxmd.com/read/29134198/%C3%AF-3-polyunsaturated-fatty-acids-direct-differentiation-of-the-membrane-phenotype-in-mesenchymal-stem-cells-to-potentiate-osteogenesis
#5
Kandice R Levental, Michal A Surma, Allison D Skinkle, Joseph H Lorent, Yong Zhou, Christian Klose, Jeffrey T Chang, John F Hancock, Ilya Levental
Mammalian cells produce hundreds of dynamically regulated lipid species that are actively turned over and trafficked to produce functional membranes. These lipid repertoires are susceptible to perturbations from dietary sources, with potentially profound physiological consequences. However, neither the lipid repertoires of various cellular membranes, their modulation by dietary fats, nor their effects on cellular phenotypes have been widely explored. We report that differentiation of human mesenchymal stem cells (MSCs) into osteoblasts or adipocytes results in extensive remodeling of the plasma membrane (PM), producing cell-specific membrane compositions and biophysical properties...
November 2017: Science Advances
https://www.readbyqxmd.com/read/29134189/toward-uniform-implementation-of-parametric-map-digital-imaging-and-communication-in-medicine-standard-in-multisite-quantitative-diffusion-imaging-studies
#6
Dariya Malyarenko, Andriy Fedorov, Laura Bell, Melissa Prah, Stefanie Hectors, Lori Arlinghaus, Mark Muzi, Meiyappan Solaiyappan, Michael Jacobs, Maggie Fung, Amita Shukla-Dave, Kevin McManus, Michael Boss, Bachir Taouli, Thomas E Yankeelov, Christopher Chad Quarles, Kathleen Schmainda, Thomas L Chenevert, David C Newitt
This paper reports on results of a multisite collaborative project launched by the MRI subgroup of Quantitative Imaging Network to assess current capability and provide future guidelines for generating a standard parametric diffusion map Digital Imaging and Communication in Medicine (DICOM) in clinical trials that utilize quantitative diffusion-weighted imaging (DWI). Participating sites used a multivendor DWI DICOM dataset of a single phantom to generate parametric maps (PMs) of the apparent diffusion coefficient (ADC) based on two models...
January 2018: Journal of Medical Imaging
https://www.readbyqxmd.com/read/29133981/electrostatic-interactions-between-polyglutamic-acid-and-polylysine-yields-stable-polyion-complex-micelles-for-deoxypodophyllotoxin-delivery
#7
Yutong Wang, Liping Huang, Yan Shen, Lidan Tang, Runing Sun, Di Shi, Thomas J Webster, Jiasheng Tu, Chunmeng Sun
To achieve enhanced physical stability of poly(ethylene glycol)-poly(d,l-lactide) polymeric micelles (PEG-PDLLA PMs), a mixture of methoxy PEG-PDLLA-polyglutamate (mPEG-PDLLA-PLG) and mPEG-PDLLA-poly(l-lysine) (mPEG-PDLLA-PLL) copolymers was applied to self-assembled stable micelles with polyion-stabilized cores. Prior to micelle preparation, the synthetic copolymers were characterized by (1)H-nuclear magnetic resonance (NMR) and infrared spectroscopy (IR), and their molecular weights were calculated by (1)H-NMR and gel permeation chromatography (GPC)...
2017: International Journal of Nanomedicine
https://www.readbyqxmd.com/read/29132536/effects-of-acute-hyperinsulinemia-on-skeletal-muscle-mitochondrial-function-reactive-oxygen-species-production-and-metabolism-in-premenopausal-women
#8
Jonathan L Warren, Sule Bulur, Fernando Ovalle, Samuel T Windham, Barbara A Gower, Gordon Fisher
BACKGROUND: Acute metabolic demands that promote excessive and/or prolonged reactive oxygen species production may stimulate changes in mitochondrial oxidative capacity. PURPOSE: To assess changes in skeletal muscle H2O2 production, mitochondrial function, and expression of genes at the mRNA and protein levels regulating energy metabolism and mitochondrial dynamics following a hyperinsulinemic-euglycemic clamp in a cohort of 11 healthy premenopausal women. METHODS: Skeletal muscle biopsies of the vastus lateralis were taken at baseline and immediately following the conclusion of a hyperinsulinemic-euglycemic clamp...
December 2017: Metabolism: Clinical and Experimental
https://www.readbyqxmd.com/read/29132173/premenstrual-syndrome-diagnosis-a-comparative-study-between-the-daily-record-of-severity-of-problems-drsp-and-the-premenstrual-symptoms-screening-tool-psst
#9
Aline Henz, Charles Francisco Ferreira, Carolina Leão Oderich, Carin Weirich Gallon, Juliana Rintondale Sodré de Castro, Maiara Conzatti, Marcelo Pio de Almeida Fleck, Maria Celeste Osório Wender
Objective To validate the premenstrual symptoms screening tool (PSST) in relation to the daily record of severity of problems (DRSP) for premenstrual syndrome (PMS) and premenstrual dysphoric disorder (PMDD) diagnoses. Methods A cross-sectional study with 127 women (20-45 years) with PMS complaints. The women were evaluated in terms of weight, height and body mass index (BMI). After using the primary care evaluation of mental disorders (PRIME-MD) questionnaire to exclude the diagnosis of depression, the PSST was completed and the women were instructed to fill out the DRSP for two consecutive menstrual cycles...
November 13, 2017: Revista Brasileira de Ginecologia e Obstetrícia
https://www.readbyqxmd.com/read/29130949/performance-of-the-surprise-question-compared-to-prediction-models-in-hemodialysis-patients-a-prospective-study
#10
Rakesh Malhotra, Xia Tao, Yuedong Wang, Yuqi Chen, Rebecca H Apruzzese, Paul Balter, Qingqing Xiao, Len A Usvyat, Peter Kotanko, Stephan Thijssen
BACKGROUND: The surprise question (SQ) ("Would you be surprised if this patient were still alive in 6 or 12 months?") is used as a mortality prognostication tool in hemodialysis (HD) patients. We compared the performance of the SQ with that of prediction models (PMs) for 6- and 12-month mortality prediction. METHODS: Demographic, clinical, laboratory, and dialysis treatment indicators were used to model 6- and 12-month mortality probability in a HD patients training cohort (n = 6,633) using generalized linear models (GLMs)...
November 7, 2017: American Journal of Nephrology
https://www.readbyqxmd.com/read/29130044/the-effect-of-pterygomasseteric-sling-s-area-in-the-postoperative-stability-after-mandibular-setback-surgery
#11
Chun-Ming Chen, Chun-Chan Ting, Jung-Hsuan Cheng, Kun-Jung Hsu, Yu-Chuan Tseng
Purpose: The purpose of the present study was to investigate the correlation between the postoperative stability and area of pterygomasseteric sling (PMS). Materials and Methods: Forty patients of mandibular prognathism were treated by isolated mandibular setback. Serial lateral cephalograms were collected (preoperatively [T1], immediately after surgery [T2], and more than 1 year postoperatively [T3]). The postoperative stability (T32) was divided into 3 groups (total, forward, and backward movements)...
2017: BioMed Research International
https://www.readbyqxmd.com/read/29127924/application-of-peroxymonosulfate-ozone-advanced-oxidation-process-for-simultaneous-waste-activated-sludge-stabilization-and-dewatering-purposes-a-comparative-study
#12
Gagik Badalians Gholikandi, Nazanin Zakizadeh, Hamidreza Masihi
In this study, the efficiency of the Peroxymonosulfate-ozone (PMS+O3) advanced oxidation process in lab scale by the aim of stabilization and dewatering the biological excess sludge was investigated and the results were compared with persulfate-ozone (PS+O3), hydrogen peroxide-ozone (H2O2+O3) and ozonation (O3) processes. The results show that the PMS+O3 is more effective than other mentioned procedures. Therefore, under optimized conditions (pH = 11, PMS/O3 = 0.06 and Dose O3 = 12.5 mmol), VS (Volatile solids) and fecal coliforms reduced respectively 42% and 89% after 60 min and the stabilized sludge in term of pathogen reduction requirements was class B...
November 8, 2017: Journal of Environmental Management
https://www.readbyqxmd.com/read/29127807/electrochemical-activation-of-persulfates-at-bdd-anode-radical-or-nonradical-oxidation
#13
Haoran Song, Linxia Yan, Jin Jiang, Jun Ma, Zhongxiang Zhang, Jiaming Zhang, Pingxin Liu, Tao Yang
The combination of persulfates (peroxydisulfate (PDS) and peroxymonosulfate (PMS)) and electrolysis using boron-doped diamond (BDD) anode is a promising green advanced oxidation process. In comparison with electrolysis alone, electrochemical activation of persulfates at BDD anode considerably enhanced the degradation of carbamazepine (CBZ). The experimental results indicate that the surface-adsorbed hydroxyl radical (HO) played the dominant role. The generally proposed nonradical oxidation mechanism ignored hydroxyl radical (HO) oxidation because low concentration of radical scavenger (<10 M methanol or 5 M tertbutanol) could not effectively scavenge the surface-adsorbed HO...
October 12, 2017: Water Research
https://www.readbyqxmd.com/read/29126394/prospective-study-of-autism-phenomenology-and-the-behavioural-phenotype-of-phelan-mcdermid-syndrome-comparison-to-fragile-x-syndrome-down-syndrome-and-idiopathic-autism-spectrum-disorder
#14
Caroline Richards, Laurie Powis, Jo Moss, Christopher Stinton, Lisa Nelson, Christopher Oliver
BACKGROUND: The limited behavioural phenotype literature on Phelan-McDermid syndrome (PMS) indicates atypically high levels of activity, impulsivity and autism spectrum disorder (ASD) behaviours. Divergent profiles of ASD in PMS are also reported, with some studies demonstrating similarities to idiopathic ASD and others indicating an uneven profile of social and communication impairments and repetitive behaviours. An evaluation of the behavioural phenotype of PMS and the prevalence and phenomenology of ASD is warranted, particularly given the causal involvement of the SHANK3 gene in the aetiology of PMS...
November 10, 2017: Journal of Neurodevelopmental Disorders
https://www.readbyqxmd.com/read/29122535/limited-output-transcranial-electrical-stimulation-lotes-2017-engineering-principles-regulatory-statutes-and-industry-standards-for-wellness-over-the-counter-or-prescription-devices-with-low-risk
#15
Marom Bikson, Bhaskar Paneri, Andoni Mourdoukoutas, Zeinab Esmaeilpour, Bashar W Badran, Robin Azzam, Devin Adair, Abhishek Datta, Xiao Hui Fang, Brett Wingeier, Daniel Chao, Miguel Alonso-Alonso, Kiwon Lee, Helena Knotkova, Adam J Woods, David Hagedorn, Doug Jeffery, James Giordano, William J Tyler
We present device standards for low-power non-invasive electrical brain stimulation devices classified as limited output transcranial electrical stimulation (tES). Emerging applications of limited output tES to modulate brain function span techniques to stimulate brain or nerve structures, including transcranial direct current stimulation (tDCS), transcranial alternating current stimulation (tACS), and transcranial pulsed current stimulation (tPCS), have engendered discussion on how access to technology should be regulated...
October 17, 2017: Brain Stimulation
https://www.readbyqxmd.com/read/29114701/prevalence-of-premenstrual-syndrome-and-its-relationship-to-depressive-symptoms-in-first-year-university-students
#16
Ayla Acikgoz, Ayfer Dayi, Tolga Binbay
To determine the prevalence of and factors influencing premenstrual syndrome (PMS) in first-year students at a university health campus and to evaluate the relationship between depression and PMS. Methods: This cross-sectional study was conducted on a population of 618 university students from March to June 2016 at Dokuz Eylül University, Izmir, Turkey. Data were collected using the Premenstrual Syndrome Scale (PMSS), Beck Depression Inventory and Student Identification Form. The data were analyzed with Version 20...
November 2017: Saudi Medical Journal
https://www.readbyqxmd.com/read/29113676/computational-lipidomics-of-the-neuronal-plasma-membrane
#17
Helgi I Ingólfsson, Timothy S Carpenter, Harsh Bhatia, Peer-Timo Bremer, Siewert J Marrink, Felice C Lightstone
Membrane lipid composition varies greatly within submembrane compartments, different organelle membranes, and also between cells of different cell stage, cell and tissue types, and organisms. Environmental factors (such as diet) also influence membrane composition. The membrane lipid composition is tightly regulated by the cell, maintaining a homeostasis that, if disrupted, can impair cell function and lead to disease. This is especially pronounced in the brain, where defects in lipid regulation are linked to various neurological diseases...
November 4, 2017: Biophysical Journal
https://www.readbyqxmd.com/read/29111950/methods-for-coping-with-premenstrual-change-development-and-validation-of-the-german-premenstrual-change-coping-inventory-pms-cope
#18
Gudrun Kaiser, Johanna N Kues, Maria Kleinstäuber, Gerhard Andersson, Cornelia Weise
During the premenstrual phase, psychological and physiological changes can occur, which are associated with different levels of disability. When they appear with Premenstrual Dysphoric Disorder (PMDD), different coping strategies may be used by women to deal with premenstrual changes. Currently no German measure exists for assessing premenstrual symptom-related coping strategies. Therefore, we developed the Premenstrual Change Coping Inventory (PMS-Cope). First, the 33-item questionnaire was tested with an exploratory factor analytic approach (EFA) in a sample of 150 women prospectively diagnosed with PMDD or severe Premenstrual Syndrome from August 2013 until March 2016...
November 7, 2017: Women & Health
https://www.readbyqxmd.com/read/29084193/-high-speed-digital-imaging-in-the-clinical-analysis-of-voice-change-as-a-parameter-of-premenstrual-syndrome
#19
Bożena Kosztyła-Hojna, Anna Łobaczuk-Sitnik, Maciej Zdrojkowski, Jolanta Biszewska, Diana Biszewska, Piotr Sitnik
Technique of high-speed digital imaging (HSDI) is unique technology, allowing assessment of real vocal fold vibrations. AIM: The aim of the study is to present the usefulness of HSDI in the diagnosis of premenstrual dysphonia as a parameter of premenstrual syndrome (PMS). MATERIALS AND METHODS: In study conducted by Department of Clinical Phonoaudiology and Logopedics at the Medical University of Białystok participated 21 women aged between 20-31 years old. HSDI technique with a digital High Speed HS camera was used for visualization of the larynx...
October 23, 2017: Polski Merkuriusz Lekarski: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29074353/clinical-features-of-regorafenib-induced-liver-injury-in-japanese-patients-from-postmarketing-experience
#20
Hiroyuki Uetake, Kenichi Sugihara, Kei Muro, Toshiyuki Sunaya, Yuka Horiuchi-Yamamoto, Hajime Takikawa
BACKGROUND: Regorafenib (Stivarga) is an oral multikinase inhibitor currently approved for patients with metastatic colorectal cancer or gastrointestinal stromal tumor. Although hepatotoxicity has been a known product profile feature of regorafenib since its initial approval, its clinical features are limited to those found in the clinical trials. PATIENTS AND METHODS: The present study was conducted in 2 analysis sets: a safety analysis set for metastatic colorectal cancer from solicited postmarketing surveillance (PMS) in Japan (n = 1227) and an analysis set for serious hepatic adverse drug reactions (n = 210) from all patients registered for regorafenib use...
September 28, 2017: Clinical Colorectal Cancer
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