keyword
https://read.qxmd.com/read/38651366/pathogenesis-of-pm-2-5-related-disorders-in-different-age-groups-children-adults-and-the-elderly
#1
REVIEW
Teerachai Amnuaylojaroen, Nichapa Parasin
The effects of PM2.5 on human health fluctuate greatly among various age groups, influenced by a range of physiological and immunological reactions. This paper compares the pathogenesis of the disease caused by PM2.5 in people of different ages, focusing on how children, adults, and the elderly are each susceptible to it because of differences in their bodies. Regarding children, exposure to PM2.5 is linked to many negative consequences. These factors consist of inflammation, oxidative stress, and respiratory problems, which might worsen pre-existing conditions and potentially cause neurotoxicity and developmental issues...
March 31, 2024: Epigenomes
https://read.qxmd.com/read/38650504/analysis-of-spatial-and-demographic-factors-associated-with-chikungunya-in-esp%C3%A3-rito-santo-state-brazil
#2
JOURNAL ARTICLE
Marcus Vinicius Salvador Clipes, Creuza Rachel Vicente, Theresa Cristina Cardoso da Silva, Lilyan Correia Resende, Crispim Cerutti Junior
BACKGROUND: Chikungunya (CHIK) emerged in Brazil in 2014 and since then several epidemics have been observed. This study aims to describe the spatial, social and demographic characteristics of individuals affected by CHIK in Espírito Santo state. METHODS: A cross-sectional study was performed using data from individuals with a confirmed diagnosis of CHIK in Espírito Santo state, Brazil, from 2018 to 2020. Monthly incidence was calculated and annual spatial distribution maps were constructed...
April 23, 2024: Transactions of the Royal Society of Tropical Medicine and Hygiene
https://read.qxmd.com/read/38646684/gender-violence-during-the-three-ages-of-life-and-the-impact-of-the-covid-19-pandemic-a-review
#3
REVIEW
Gaetano Di Donna, Pierpaolo Di Lorenzo, Carmen Imma Aquino, Mariagrazia Marisei, Claudia Casella, Daniela Surico, Massimo Niola, Maurizio Guida
Children, women, and older people suffer different types of violence, which appears to have been exacerbated during the COVID-19 pandemic and the relative lockdown. The aim of this study is to analyze the literature about gender violence and abuse in the different ages of life and during the COVID-19 lockdown. Data were obtained from an electronic literature search using various online sources such as PubMed, Google Scholar, Science Direct and Web of Science. The terms "child abuse" were the most frequently used, followed in frequency by "gender violence," "femicide," and, lastly, "elderly abuse...
April 22, 2024: Int J Soc Determinants Health Health Serv
https://read.qxmd.com/read/38638133/apigenin-and-rutaecarpine-reduce-the-burden-of-cellular-senescence-in-bone-marrow-stromal-stem-cells
#4
JOURNAL ARTICLE
Dalia Ali, Meshail Okla, Sarah Abuelreich, Radhakrishnan Vishnubalaji, Nicholas Ditzel, Rimi Hamam, Justyna M Kowal, Ahmed Sayed, Abdullah Aldahmash, Nehad M Alajez, Moustapha Kassem
INTRODUCTION: Osteoporosis is a systemic age-related disease characterized by reduced bone mass and microstructure deterioration, leading to increased risk of bone fragility fractures. Osteoporosis is a worldwide major health care problem and there is a need for preventive approaches. METHODS AND RESULTS: Apigenin and Rutaecarpine are plant-derived antioxidants identified through functional screen of a natural product library (143 compounds) as enhancers of osteoblastic differentiation of human bone marrow stromal stem cells (hBMSCs)...
2024: Frontiers in Endocrinology
https://read.qxmd.com/read/38636331/predictive-health-monitoring-leveraging-artificial-intelligence-for-early-detection-of-infectious-diseases-in-nursing-home-residents-through-discontinuous-vital-signs-analysis
#5
JOURNAL ARTICLE
Alberto Garcés-Jiménez, María-Luz Polo-Luque, Juan A Gómez-Pulido, Diego Rodríguez-Puyol, José M Gómez-Pulido
This research addresses the problem of detecting acute respiratory, urinary tract, and other infectious diseases in elderly nursing home residents using machine learning algorithms. The study analyzes data extracted from multiple vital signs and other contextual information for diagnostic purposes. The daily data collection process encounters sampling constraints due to weekends, holidays, shift changes, staff turnover, and equipment breakdowns, resulting in numerous nulls, repeated readings, outliers, and meaningless values...
April 14, 2024: Computers in Biology and Medicine
https://read.qxmd.com/read/38631257/treatment-of-elderly-patients-with-head-and-neck-cancer-in-an-aging-society-focus-on-geriatric-assessment-and-surgical-treatment
#6
REVIEW
Ryo Ishii, Akira Ohkoshi, Yukio Katori
Previous studies of the treatment of elderly head and neck cancer (HNC) patients were very limited and sometimes controversial. Although conclusions differ across various reports, it is often concluded that advanced chronological age does not directly affect prognosis, but that comorbidities and declines in physical and cognitive functions promote the occurrence of adverse events, especially with surgical treatment. Geriatric assessment (GA) and its screening tools are keys to help us understand overall health status and problems, predict life expectancy and treatment tolerance, and to influence treatment choices and interventions to improve treatment compliance...
April 16, 2024: Auris, Nasus, Larynx
https://read.qxmd.com/read/38630374/geo-visualizing-the-hotspots-of-smog-induced-health-effects-in-district-gujranwala-pakistan-a-community-perspective
#7
JOURNAL ARTICLE
Shakeel Mahmood, Aqib Ali, Huda Jamal Jumaah
This study aims to examine the health effects of smog on different age groups in Gujranwala and its associated health effects. To achieve this, primary data was gathered through a questionnaire survey focused on health issues faced by elderly individuals during the smog season. The results of the survey revealed that older adults in Gujranwala are particularly vulnerable to a range of health problems during this period, including coughing, throat infections, irritated eyes, runny noses, shortness of breath, chest pain while breathing, wheezing, asthma, heart problems, and respiratory issues...
April 17, 2024: Environmental Monitoring and Assessment
https://read.qxmd.com/read/38625858/fall-prediction-in-a-quiet-standing-balance-test-via-machine-learning-is-it-possible
#8
JOURNAL ARTICLE
Juliana Pennone, Natasha Fioretto Aguero, Daniel Marczuk Martini, Luis Mochizuki, Alexandre Alarcon do Passo Suaide
The elderly population is growing rapidly in the world and falls are becoming a big problem for society. Currently, clinical assessments of gait and posture include functional evaluations, objective, and subjective scales. They are considered the gold standard to indicate optimal mobility and performance individually, but their sensitivity and specificity are not good enough to predict who is at higher risk of falling. An innovative approach for fall prediction is the machine learning. Machine learning is a computer-science area that uses statistics and optimization methods in a large amount of data to make outcome predictions...
2024: PloS One
https://read.qxmd.com/read/38622895/syringaresinol-attenuates-tau-phosphorylation-and-ameliorates-cognitive-dysfunction-induced-by-sevoflurane-in-aged-rats
#9
JOURNAL ARTICLE
Simin Zheng, Yunpeng Teng, Hongtao Liu, Jiaxuan He, Shaobo Zhang, Hongfei Xiong
Cognitive dysfunction following anesthesia with agents such as sevoflurane is a significant clinical problem, particularly in elderly patients. This study aimed to explore the protective effects of the phytochemical syringaresinol (SYR) against sevoflurane-induced cognitive deficits in aged Sprague-Dawley rats and to determine the underlying mechanisms involved. We assessed the impact of SYR on sevoflurane-induced cognitive impairment, glial activation, and neuronal apoptosis through behavioral tests (Morris water maze), immunofluorescence, Western blotting for key proteins involved in apoptosis and inflammation, and enzyme-linked immunosorbent assays for interleukin-1β, tumor necrosis factor-α, and interleukin-6...
April 15, 2024: Journal of Neuropathology and Experimental Neurology
https://read.qxmd.com/read/38622542/exploring-the-knowledge-and-skills-for-effective-family-caregiving-in-elderly-home-care-a-qualitative-study
#10
JOURNAL ARTICLE
Gebrezabher Niguse Hailu, Muntaha Abdelkader, Feven Asfaw, Hailemariam Atsbeha Meles
BACKGROUND: Family caregivers play a crucial role in providing physical, emotional, and social support to the elderly, allowing them to maintain their independence and stay in their preferred living environment. However, family caregivers face numerous challenges and require specific knowledge and skills to provide effective care. Therefore, understanding the knowledge and skills required for effective family caregiving in elderly home care is vital to support both the caregivers and the elderly recipients...
April 15, 2024: BMC Geriatrics
https://read.qxmd.com/read/38622013/relationship-between-pain-and-dementia-the-mediating-effect-of-depression-among-chinese-elderly
#11
JOURNAL ARTICLE
Wenrong Duan, Jian Huang, Qiuling Huang, Birong Dong
BACKGROUND: Chronic pain poses a significant problem for older adults and may potentially impact cognitive function. This study aimed to examine the cross-sectional relationship between pain severity and cognitive function in elderly individuals residing in the community. Additionally, this study sought to examine the mediating effect of depression on the relationship between pain and dementia. METHODS: The study sample was derived from the 2018 China Health and Aging Longitudinal Study (CHARLS), comprising cross-sectional data from 4559 community residents aged 65 years or older...
April 2024: Actas Españolas de Psiquiatría
https://read.qxmd.com/read/38617580/elderly-s-homesickness-development-of-elderly-homesickness-questionnaire
#12
JOURNAL ARTICLE
Zeming Deng, Yuehong Qiu, Xueer Xiao, Can Jiao
INTRODUCTION: Homesickness is a result of migration, and is related to adjustment difficulties and health problems, as well as clinical disorders. The aim of this study was to measure and explore the homesickness of Chinese elderly. METHODS: A total of 355 non-local Chinese elderly in Shenzhen were recruited to measure demographic information and homesickness. and tested for reliability and validity. Patterns and influences of homesickness among Chinese elderly were explored through latent profile analysis and One-way ANOVA on the basis of EHQ...
2024: Psychology Research and Behavior Management
https://read.qxmd.com/read/38616372/awareness-and-self-reported-knowledge-and-training-on-nutrition-in-older-people-among-primary-care-practitioners
#13
JOURNAL ARTICLE
L Rodríguez-Mañas, J M Moreno-Villares, J Álvarez Hernández, A A Romero Secín, M L López Díaz-Ufano, F Suárez González, A Costa-Grille, J López-Miranda, J M Fernández-Garcia
OBJECTIVES: To assess the awareness and training of primary care physicians on nutrition in older patients. DESIGN: Observational, real-world data survey. SETTING: Primary Care. PARTICIPANTS: One hundred sixty-two physicians, generalists and specialists, working in primary care. MEASUREMENTS: Participants received an online questionnaire with 18 questions concerning the importance of nutrition, degree of knowledge, needs, and training in nutrition...
2024: Journal of Frailty & Aging
https://read.qxmd.com/read/38616290/informed-consent-in-clinical-practice-old-problems-new-challenges
#14
JOURNAL ARTICLE
Isaac Ks Ng
Informed consent is a fundamental tenet of patient-centred clinical practice as it upholds the ethical principle of patient autonomy and promotes shared decision-making. In the medicolegal realm, failure to meet the accepted standards of consent can be considered as medical negligence which has both legal and professional implications. In general, valid consent requires three core components: (1) the presence of mental capacity - characterised by the patient's ability to comprehend, retain information, weigh options and communicate the decision, (2) adequate information disclosure - based on the 'reasonable physician' or 'reasonable patient' standards and (3) voluntariness in decision-making...
April 14, 2024: Journal of the Royal College of Physicians of Edinburgh
https://read.qxmd.com/read/38609163/manhattan-vision-screening-and-follow-up-study-nyc-sight-a-nested-cross-sectional-assessment-of-falls-risk-within-a-cluster-randomised-trial
#15
JOURNAL ARTICLE
Lisa A Hark, Yujia Wang, Prakash Gorroochurn, Phyllis R Simon, Stefania C Maruri, Desiree R Henriquez, Daniel F Diamond, Jason D Horowitz, Lisa Park, Qing Wang, James D Auran, Jailine Carrion, David S Friedman, Jeffrey L Liebmann, George A Cioffi, Noga Harizman
BACKGROUND: To investigate the feasibility of using the Stopping Elderly Accidents, Deaths and Injuries (STEADI) Falls Risk Tool Kit during community-based eye health screenings to assess falls risk of participants enrolled in the Manhattan Vision Screening and Follow-Up Study (NYC-SIGHT). METHODS: Cross-sectional analysis of data from a 5-year prospective, cluster-randomised clinical trial conducted in affordable housing developments in New York City in adults age 40 years and older...
April 12, 2024: British Journal of Ophthalmology
https://read.qxmd.com/read/38607735/age-related-dysfunction-in-balance-a-comprehensive-review-of-causes-consequences-and-interventions
#16
REVIEW
Jixian Wang, Yongfang Li, Guo-Yuan Yang, Kunlin Jin
This review delves into the multifaceted aspects of age-related balance changes, highlighting their prevalence, underlying causes, and the impact they have on the elderly population. Central to this discussion is the exploration of various physiological changes that occur with aging, such as alterations in the vestibular, visual, proprioceptive systems, and musculoskeletal degeneration. We examine the role of neurological disorders, cognitive decline, and medication side effects in exacerbating balance issues...
March 21, 2024: Aging and Disease
https://read.qxmd.com/read/38606809/predictors-of-fall-protection-motivation-among-older-adults-in-rural-communities-in-a-middle-income-country-a-cross-sectional-study-using-the-protection-motivation-theory
#17
JOURNAL ARTICLE
Mei Fong Ong, Kim Lam Soh, Rosalia Saimon, Hasni Idayu Saidi, Ing Khieng Tiong, Wai Wai Myint, Manfred Mortell, Salimah Japar
AIMS: To evaluate factors associated with fall protection motivation to engage in fall preventive behaviour among rural community-dwelling older adults aged 55 and above using the protection motivation theory scale. DESIGN: A cross-sectional study. METHODS: The study was conducted in a healthcare clinic in Malaysia, using multistage random sampling from November 2021 to January 2022. Three hundred seventy-five older adults aged 55 and older were included in the final analysis...
April 12, 2024: Journal of Advanced Nursing
https://read.qxmd.com/read/38605804/a-cross-sectional-study-to-assess-the-under-nutrition-amongst-the-elderly-population-in-a-rural-area-of-district-gautam-buddha-nagar-uttar-pradesh
#18
JOURNAL ARTICLE
Meraj Gohar, Kabita Barua, Shalini Srivastava, Harsh Mahajan, Amit S Pawaiya, Sachin K Nagar
BACKGROUND: Ageing is a universal process. It is influenced by a person's genetic makeup, lifestyle, and environmental factors. Nutrition plays a significant role in modulation of ageing. In developing countries like India, the health and nutritional status of the elderly population is not satisfactory. OBJECTIVES: The current study was done to assess undernutrition amongst the elderly population and to find the various associations with sociodemographic factors and social determinants...
February 2024: Journal of Family Medicine and Primary Care
https://read.qxmd.com/read/38605326/association-of-8-hydroxy-2-deoxyguanosine-with-motoric-cognitive-risk-in-elderly-chinese-people-rugao-longevity-and-aging-cross-sectional-study
#19
JOURNAL ARTICLE
Qingqing Dai, Yajun Ma, Chang Liu, Ruixue Zhao, Qi Chen, Weijia Chen, Xiaofeng Wang, Xiaoyan Jiang, Shujuan Li
BACKGROUND: Motor cognitive risk syndrome (MCR) represents a critical pre-dementia and disability state characterized by a combination of objectively measured slow walking speed and subjective memory complaints (SMCs). This study aims to identify risk factors for MCR and investigate the relationship between plasma levels of 8-hydroxy-2'-deoxyguanosine (8-OHdG) and MCR among Chinese community-dwelling elderly populations. METHODS: A total of 1312 participants were involved in this study based on the data of the Rugao Longevity and Aging Study (RuLAS)...
April 11, 2024: BMC Geriatrics
https://read.qxmd.com/read/38603945/-bibliometric-study-and-analysis-of-citation-networks-of-visual-screening-in-primary-care
#20
JOURNAL ARTICLE
R Coca-Serrano, M A Sánchez-Tena, C Álvarez-Peregrina, C Martínez-Pérez, M Moriche-Carretero
AIM: Screenings make it possible to detect anomalies that can be treated and identify patients who require referral to a specialist. The objective is to identify the different areas of research and determine the most cited publications on screening in primary care. METHODS: An analysis of publications and visualization of citation networks has been carried out using the Citation Network Explorer software. The bibliographic search was carried out with the Web of Science (WOS) database using the search term: "screening AND (vision OR eye OR ocular OR visual)"...
April 10, 2024: Semergen
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