Nicola Zizzo, Rosa Patruno, Francesco Alfredo Zito, Aldo Di Summa, Antonella Tinelli, Sante Troilo, Andrea Misino, Eustachio Ruggieri, Veronica Goffredo, Cosmo Damiano Gadaleta, Girolamo Ranieri
Published data strongly suggest that tumor progression and malignancy are associated with increased angiogenesis. However, no data have been published concerning the relationship between microvascular density (MVD), tumor cytosol, and blood vascular endothelial growth factor (VEGF) concentrations in canine non-Hodgkin lymphoma (C-NHL), a neoplasm that shares biological and clinical characteristics with human NHL. We have evaluated MVD and tumor cytosol, serum (S), platelet-poor plasma (P-PP), plasma-activated platelet rich (P-APR) VEGF concentration in a series of 63 B-cells C-NHL by means of immunohistochemistry and enzyme-linked immuno-sorbent assay (ELISA) detection of VEGF...
February 2010: Leukemia & Lymphoma