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Cervical pathology and colposcopy guidelines

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https://www.readbyqxmd.com/read/30146348/update-on-primary-hpv-screening-for-cervical-cancer-prevention
#1
REVIEW
Anthony E Rizzo, Sarah Feldman
In the coming decade, primary testing for human papillomavirus (HPV) will likely become the standard of care for cervical cancer screening in both low- and high-resource settings. This change comes as evidence has accumulated to support HPV testing as more sensitive to detect high-grade precancerous disease. Furthermore, negative HPV testing has demonstrated a lower cumulative incidence of cervical intraepithelial neoplasia (CIN) grade 3 or worse pathology (CIN3+) when compared to negative "Pap smears" over several rounds of screening...
August 14, 2018: Current Problems in Cancer
https://www.readbyqxmd.com/read/29957658/impact-of-acetic-acid-on-hpv-testing-using-hybrid-capture-2
#2
Annick Pina, Philippe Sauthier, François Coutlée, Helen Trottier, Marie-Hélène Mayrand
As per the American Society for Colposcopy and Cervical Pathology guidelines, human papillomavirus (HPV) testing is currently used as part of cervical cancer screening and during colposcopy follow-up. The present project evaluated if the application of acetic acid (AA) impacts HPV test results. METHODS: We conducted a prospective nonrandomized interventional study. Participants referred for colposcopy were eligible if immunocompetent, older than 18 years, and not pregnant. Women in group A (controls) received 2 consecutive HPV tests without application of AA...
October 2018: Journal of Lower Genital Tract Disease
https://www.readbyqxmd.com/read/29874685/guidelines-for-hpv-dna-testing-for-cervical-cancer-screening-in-brazil
#3
Luiz Carlos Zeferino, Joana Bragança Bastos, Diama Bhadra Andrade Peixoto do Vale, Rita Maria Zanine, Yara Lucia Mendes Furtado de Melo, Walquíria Quida Salles Pereira Primo, Flávia de Miranda Corrêa, Isabel Cristina Chulvis do Val, Fábio Russomano
Evidence-based clinical guidelines ensure best practice protocols are available in health care. There is a widespread use of human papillomavirus deoxyribonucleic acid (HPV-DNA) tests in Brazil, regardless of the lack of official guidelines. On behalf of the Brazilian Association for the Lower Genital Tract Pathology and Colposcopy (ABPTGIC, in the Portuguese acronym), a team of reviewers searched for published evidence and developed a set of recommendations for the use of HPV-DNA tests in cervical cancer screening in Brazil...
June 2018: Revista Brasileira de Ginecologia e Obstetrícia
https://www.readbyqxmd.com/read/29797678/immediate-histopathologic-follow-up-of-cervista-and-aptima-high-risk-hpv-assays-in-women-with-lsil-cytology
#4
Huina Zhang, Kavita R Varma, Min Han, Jonee Matsko, Chengquan Zhao
BACKGROUND: Recent guidelines recommended the optional deferral of colposcopy for postmenopausal women with low-grade squamous intraepithelial lesion (LSIL) Papanicolaou (Pap) test results and negative human papillomavirus (HPV) testing. The objective of the current study was to assess the histopathologic follow-up of Cervista and Aptima high-risk HPV (hrHPV) testing in patients with LSIL cytology. METHODS: Women with LSIL Pap test results and Cervista or Aptima hrHPV testing results were retrospectively identified from June 2013 through July 2017...
August 2018: Cancer Cytopathology
https://www.readbyqxmd.com/read/29733302/excess-cost-of-cervical-cancer-screening-beyond-recommended-screening-ages-or-after-hysterectomy-in-a-single-institution
#5
Deanna Teoh, Gretchen Hultman, McKenzie DeKam, Rachel Isaksson Vogel, Levi S Downs, Melissa A Geller, Chap Le, Genevieve Melton, Shalini Kulasingam
OBJECTIVE: The aim of the study was to estimate the excess cost of guideline nonadherent cervical cancer screening in women beyond the recommended screening ages or posthysterectomy in a single healthcare system. MATERIALS AND METHODS: All Pap tests performed between September 1, 2012, and August 31, 2014, in women younger than 21 years, older than 65 years, or after hysterectomy, were coded as guideline adherent or nonadherent per the 2012 America Society of Colposcopy and Clinical Pathology guidelines...
July 2018: Journal of Lower Genital Tract Disease
https://www.readbyqxmd.com/read/29671553/cervical-cancer-screening
#6
Caitlyn M Rerucha, Rebecca J Caro, Vernon L Wheeler
Screening in women has decreased the incidence and mortality of cervical cancer. Precancerous cervical lesions (cervical intraepithelial neoplasias) and cervical carcinomas are strongly associated with sexually-transmitted high-risk human papillomavirus (HPV) infection, which causes more than 99% of cervical cancers. Screening methods include cytology (Papanicolaou test) and HPV testing, alone or in combination. The American Academy of Family Physicians and the U.S. Preventive Services Task Force recommend starting screening in immunocompetent, asymptomatic women at 21 years of age...
April 1, 2018: American Family Physician
https://www.readbyqxmd.com/read/29660849/comparison-of-human-papillomavirus-genotyping-and-cytology-triage-compact-study-design-methods-and-baseline-results-in-14-642-women
#7
MULTICENTER STUDY
Satomi Aoyama-Kikawa, Hiromasa Fujita, Sharon J B Hanley, Mitsunori Kasamo, Kokichi Kikuchi, Toshihiko Torigoe, Yoshihiro Matsuno, Akiko Tamakoshi, Takayuki Sasaki, Motoki Matsuura, Yasuhito Kato, Peixin Dong, Hidemichi Watari, Tsuyoshi Saito, Kazuo Sengoku, Noriaki Sakuragi
Although cytology-based screening programs have significantly reduced mortality and morbidity from cervical cancer, the global consensus is that primary human papillomavirus (HPV) testing for cervical screening increases detection of high-grade cervical intraepithelial neoplasia (CIN) and invasive cancer. However, the optimal triage strategy for HPV-positive women to avoid over-referral to colposcopy may be setting specific. As Japan requires data that have been generated domestically to modify screening guidelines, we conducted a 3-year prospective study, COMparison of HPV genotyping And Cytology Triage (COMPACT), to evaluate the potential role of HPV16/18 partial genotyping and cytology for primary HPV screening...
June 2018: Cancer Science
https://www.readbyqxmd.com/read/29528922/quality-improvement-to-demonstrate-the-lack-of-reliability-of-the-human-papillomavirus-mrna-assay-to-identify-women-with-latent-human-papillomavirus-infections
#8
Sarah Cotton, Robert E Brown, Elizabeth K Nugent, Sonia C Robazetti, Pamela D Berens, Judith A Smith
OBJECTIVE: To assess the consistency between human papillomavirus (HPV) mRNA testing in women with a history of previous HPV infections diagnosed by HPV DNA assay and the potential effects on follow-up HPV screening. METHODS: This was a quality improvement study that used data from a pathology laboratory software database reviewed from November 2014 to June 2016 to identify female patients aged 30 years or older with greater than one HPV-positive result, including one or more HPV mRNA assay results and one or more documented HPV DNA assay results for comparison...
April 2018: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29460502/immediate-biopsy-of-cervical-cytology-negative-and-non-hpv-16-18-oncogenic-types-positive-patients
#9
İbrahim Karaca, Mustafa Öztürk, Cihan Comba, Gökhan Demirayak, İsmail Alay, Volkan Şakir Erdoğan, Murat Hoşgören, Levent Yaşar
BACKGROUND: According to the American Society of Colposcopy and Cervical Pathology (ASCCP), a co-test is recommended for patients one year after the detection of non-HPV 16/18 viral types in association with a negative cervical cytology. In this study, we used immediate colposcopy to evaluate the risks to the patient during the one year waiting period. METHODS: We included 544 Hpv-positive/cervical cytology-negative patients who underwent cervical cancer screening from June 2015 to June 2017...
April 2018: Diagnostic Cytopathology
https://www.readbyqxmd.com/read/29365341/improving-the-accuracy-of-a-clinical-decision-support-system-for-cervical-cancer-screening-and-surveillance
#10
K E Ravikumar, Kathy L MacLaughlin, Marianne R Scheitel, Maya Kessler, Kavishwar B Wagholikar, Hongfang Liu, Rajeev Chaudhry
BACKGROUND: Clinical decision support systems (CDSS) for cervical cancer prevention are generally limited to identifying patients who are overdue for their next routine/next screening, and they do not provide recommendations for follow-up of abnormal results. We previously developed a CDSS to automatically provide follow-up recommendations based on the American Society of Colposcopy and Cervical Pathology (ASCCP) guidelines for women with both previously normal and abnormal test results leveraging information available in the electronic medical record (EMR)...
January 2018: Applied Clinical Informatics
https://www.readbyqxmd.com/read/29333334/the-effect-of-the-2012-asccp-consensus-guideline-for-abnormal-cervical-cytology-on-resident-colposcopy-training
#11
Cori-Ann M Hirai, Bliss Kaneshiro, Mark K Hiraoka
The primary objective was to determine the theoretical number of colposcopies at a resident clinic if the 2012 American Society for Colposcopy and Cervical Pathology (ASCCP) guidelines were applied. The secondary objective was to determine the actual number of colposcopies before and after the ASCCP guidelines. This was a two-part descriptive study. The first part applied the 2012 ASCCP guidelines to all pre-guideline colposcopy cases at a single resident clinic. These theoretical results were then compared to the actual number of colposcopies...
January 2018: Hawai'i Journal of Medicine & Public Health: a Journal of Asia Pacific Medicine & Public Health
https://www.readbyqxmd.com/read/29212399/conservative-management-of-cin2-national-audit-of-british-society-for-colposcopy-and-cervical-pathology-members-opinion
#12
Madeleine Macdonald, John H F Smith, John A Tidy, Julia E Palmer
There is no doubt that organised cervical screening programmes have significantly reduced the rates of cervical cancer by detection and treatment of high-grade cervical intraepithelial neoplasia (CIN2, CIN3). National UK guidelines do not differentiate between CIN2 and CIN3 as separate entities and recommend treatment for both, although a degree of uncertainty exists regarding the natural history of CIN2. This national survey of British Society for Colposcopy and Cervical Pathology members aimed to assess attitudes towards conservative management (CM) of CIN2 in the UK and identify potential selection criteria...
April 2018: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28953116/risks-of-cin-2-cin-3-and-cancer-by-cytology-and-human-papillomavirus-status-the-foundation-of-risk-based-cervical-screening-guidelines
#13
Maria Demarco, Thomas S Lorey, Barbara Fetterman, Li C Cheung, Richard S Guido, Nicolas Wentzensen, Walter K Kinney, Nancy E Poitras, Brian Befano, Philip E Castle, Mark Schiffman
OBJECTIVES: The next round of the American Society for Colposcopy and Cervical Pathology (ASCCP)-sponsored cervical cancer screening and management guidelines will recommend clinical actions based on risk, rather than test-based algorithms. This article gives preliminary risk estimates for the screening setting, showing combinations of the 2 most important predictors, human papillomavirus (HPV) status and cytology result. MATERIALS AND METHODS: Among 1,262,713 women aged 25 to 77 years co-tested with HC2 (Qiagen) and cytology at Kaiser Permanente Northern California, we estimated 0-5-year cumulative risk of cervical intraepithelial neoplasia (CIN) 2+, CIN 3+, and cancer for combinations of cytology (negative for intraepithelial lesion or malignancy [NILM], atypical squamous cells of undetermined significance [ASC-US], low-grade squamous intraepithelial lesion [LSIL], atypical squamous cells cannot exclude HSIL [ASC-H], high-grade squamous intraepithelial lesion [HSIL], atypical glandular cells [AGC]) and HPV status...
October 2017: Journal of Lower Genital Tract Disease
https://www.readbyqxmd.com/read/28953114/systematic-review-of-international-colposcopy-quality-improvement-guidelines
#14
REVIEW
Edward J Mayeaux, Akiva P Novetsky, David Chelmow, Kim Choma, Francisco Garcia, Angela H Liu, Theognosia Papasozomenos, Mark H Einstein
OBJECTIVES: The American Society for Colposcopy and Cervical Pathology Colposcopy Standards Committee organized multiple working groups to draft colposcopy standards for the United States. As part of this project, international quality assurance and improvement measures were examined. MATERIALS AND METHODS: The quality improvement working group performed a systematic review of the literature to collate international guidelines related to quality improvement. Source guidelines were collected using searches in Medline, Google Scholar, the International Federation of Cervical Pathology and Colposcopy Web site, other regional colposcopy group's Web sites, and communications with International Federation of Cervical Pathology and Colposcopy board of directors' members and other expert members of various national groups...
October 2017: Journal of Lower Genital Tract Disease
https://www.readbyqxmd.com/read/28953113/asccp-colposcopy-standards-colposcopy-quality-improvement-recommendations-for-the-united-states
#15
Edward J Mayeaux, Akiva P Novetsky, David Chelmow, Francisco Garcia, Kim Choma, Angela H Liu, Theognosia Papasozomenos, Mark H Einstein, L Stewart Massad, Nicolas Wentzensen, Alan G Waxman, Christine Conageski, Michelle J Khan, Warner K Huh
OBJECTIVES: The American Society for Colposcopy and Cervical Pathology (ASCCP) Colposcopy Standards recommendations address the role of and approach to colposcopy and biopsy for cervical cancer prevention in the United States. The recommendations were developed by an expert working group appointed by ASCCP's Board of Directors. The ASCCP Quality Improvement Working Group developed evidence-based guidelines to promote best practices and reduce errors in colposcopy and recommended indicators to measure colposcopy quality...
October 2017: Journal of Lower Genital Tract Disease
https://www.readbyqxmd.com/read/28953112/asccp-colposcopy-standards-how-do-we-perform-colposcopy-implications-for-establishing-standards
#16
Alan G Waxman, Christine Conageski, Michelle I Silver, Candice Tedeschi, Elizabeth A Stier, Barbara Apgar, Warner K Huh, Nicolas Wentzensen, L Stewart Massad, Michelle J Khan, Edward J Mayeaux, Mark H Einstein, Mark H Schiffman, Richard S Guido
OBJECTIVES: The American Society for Colposcopy and Cervical Pathology (ASCCP) Colposcopy Standards recommendations address the role of and approach to colposcopy and biopsy for cervical cancer prevention in the United States. The recommendations were developed by an expert working group appointed by ASCCP's Board of Directors. Working group 3 defined colposcopy procedure guidelines for minimum and comprehensive colposcopy practice and evaluated the use of colposcopy adjuncts. MATERIALS AND METHODS: The working group performed a systematic literature review to identify best practices in colposcopy methodology and to evaluate the use of available colposcopy adjuncts...
October 2017: Journal of Lower Genital Tract Disease
https://www.readbyqxmd.com/read/28885082/human-papillomavirus-testing-by-veterans-administration-women-s-health-providers-are-they-adhering-to-guidelines
#17
Laura D Hallett, Megan R Gerber
BACKGROUND: Evidence-based guidelines have been created by professional societies, including the United States Preventive Services Task Force (USPSTF) and American Society for Colposcopy and Cervical Pathology (ASCCP), for use of human papillomavirus (HPV) cotesting in cervical cancer screening. We investigated whether Veterans Health Administration (VA) providers at one VA medical center follow these guidelines. MATERIALS AND METHODS: Retrospective chart review of women aged 21-65 who had an HPV test ordered with pap testing in fiscal year 2014 at one Veterans Administration (VA) medical center to evaluate concordance of HPV ordering with screening (USPSTF) and management (ASCCP) guidelines...
February 2018: Journal of Women's Health
https://www.readbyqxmd.com/read/28843222/accuracy-of-cervical-visual-inspection-with-acetic-acid-guide-for-4-quadrant-random-cervical-biopsies-by-general-practitioners-in-women-with-abnormal-pap-smears
#18
Patrada Suwansura, Darigar Darojn
Objective: To study the performance of visual inspection with acetic acid plus 4-quadrant cervical biopsy (V4B) by general practitioners in detecting high grade cervical lesion, compared to highest histopathologic grade from the American Society for Colposcopy and Cervical Pathology American Society for Colposcopy and Cervical Pathology (ASCCP) 2013 work up guidelines. Materials and methods: Patients with abnormal cervical cytologic screening results suggesting low grade lesions underwent V4B by general practitioners followed by colposcopy on the same day bases on ASCCP 2013 guidelines...
August 27, 2017: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/28791267/atypical-squamous-cells-of-undetermined-significance-and-low-grade-squamous-intraepithelial-lesion-triage-in-korean-women-revisiting-the-2012-american-society-of-colposcopy-and-cervical-pathology-screening-guidelines
#19
Ji Yeon Hyun, Kyung-Jin Min, Sun Young Yang, Jae-Kwan Lee, Jin Hwa Hong
OBJECTIVE: To determine whether triage for atypical squamous cells of undetermined significance (ASC-US) and low-grade squamous intraepithelial lesion (LSIL) from the updated American Society for Colposcopy and Cervical Pathology cervical cancer screening guidelines is applicable in Korean women. METHODS: We investigated women with ASC-US or LSIL including referred from local hospitals visited for cervical cancer screening at Korea University Guro Hospital from February 2004 to December 2014...
July 2017: Obstetrics & Gynecology Science
https://www.readbyqxmd.com/read/28725782/use-of-pathology-data-to-improve-high-value-treatment-of-cervical-neoplasia
#20
Barbara S Ducatman, Mahreen Hashmi, Morgan Darrow, Melina B Flanagan, Pamela Courtney, Alan M Ducatman
We investigated the influence of pathology data to improve patient outcomes in the treatment of high-grade cervical neoplasia in a joint pathology and gynecology collaboration. Two of us (B.S.D. and M.D.) reviewed all cytology, colposcopy and surgical pathology results, patient history, and pregnancy outcomes from all patients with loop electrosurgical excision procedure specimens for a 33-month period (January 2011-September 2013). We used this to determine compliance to 2006 consensus guidelines for the performance of loop electrosurgical excision procedure and shared this information in 2 interprofessional and interdisciplinary educational interventions with Obstetrics/Gynecology and Pathology faculty at the end of September 2013...
January 2016: Academic Pathology
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