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https://www.readbyqxmd.com/read/29152934/a-prospective-randomised-trial-of-the-ambu-auragain-laryngeal-mask-versus-the-lma-protector-airway-in-paralysed-anaesthetised-adult-men
#1
Berthold Moser, Laurent Audigé, Christian Keller, Joseph Brimacombe, Lukas Gasteiger, Heinz R Bruppacher
BACKGROUND: We hypothesise that oropharyngeal leak pressures differ between the LMA® ProtectorTM and the AuraGainTM, two novel supraglottic airway devices offering the possibility of intubation. METHODS: 98 male patients ASAI-II were randomly assigned to the AuraGainTM or ProtectorTM group. Oropharyngeal leak pressure was measured by incrementing cuff volume in 10 ml steps from 10 ml to 40 ml. The primary outcome was oropharyngeal leak pressure at 40 ml cuff volume...
November 17, 2017: Minerva Anestesiologica
https://www.readbyqxmd.com/read/29152207/endotracheal-intubation-in-patients-with-difficult-airway-using-laryngeal-mask-airway-with-bougie-versus-video-laryngoscopy
#2
Hesameddin Modir, Esmail Moshiri, Bita Malekianzadeh, Gholamreza Noori, Abolfazl Mohammadbeigi
Airway management is essential for safe anesthesia and endotracheal intubation is the most important procedure by which critically ill patients can be better managed, especially if done quickly and successfully. This study aimed to compare the techniques of intubation through laryngeal mask airway (LMA) using a bougie versus video laryngoscopy (VL) regarding to intubation success and the quality of intubation indices in patients with difficult airways. This randomized clinical trial was performed on 96 patients aged 16-76 years with Mallampati class 3 or 4 who underwent elective surgery...
July 2017: Medical Gas Research
https://www.readbyqxmd.com/read/29142433/prosopis-juliflora-pods-alkaloid-rich-fraction-in-vitro-anthelmintic-activity-on-goat-gastrointestinal-parasites-and-its-cytotoxicity-on-vero-cells
#3
Helimar Gonçalves Lima, Danilo Cavalcante Gomes, Nathália Silva Santos, Êuder Reis Dias, Mariana Borges Botura, Maria José Moreira Batatinha, Alexsandro Branco
Background: This study was designed to assess the in vitro anthelmintic activity of the fraction containing alkaloid from Prosopis juliflora pods on goat gastrointestinal nematodes using the egg hatch assay (EHA), larval migration inhibition assay (LMIA), and larval motility assay (LMA). Materials and Methods: The alkaloid-rich fraction (AF) - content juliprosopine as major alkaloid - was obtained from ethyl acetate extract after fractionation in Sephadex LH-20 chromatography column and its characterization were made by nuclear magnetic resonance analysis together with literature data comparison...
October 2017: Pharmacognosy Magazine
https://www.readbyqxmd.com/read/29131411/the-salt-matters-enhanced-reversibility-of-li-o2-batteries-with-a-li-cf3-so2-n-c4-f9-so2-n-based-electrolyte
#4
Bo Tong, Jun Huang, Zhibin Zhou, Zhangquan Peng
The safety hazards and cycle instability of lithium metal anodes (LMA) constitute significant barriers to progress in lithium metal batteries. This situation is worse in Li-O2 batteries because the LMA is prone to be chemically attacked by O2 shuttled from the cathode. Notwithstanding, efforts on LMA are much sparse than those on the cathode in the realm of Li-O2 batteries. Here, a novel lithium salt of Li[(CF3 SO2 )(n-C4 F9 SO2 )N] (LiTNFSI) is reported, which can effectively suppress the parasitic side reactions and dendrite growth of LMA during cycling and thereby significantly enhance the overall reversibility of Li-O2 batteries...
November 13, 2017: Advanced Materials
https://www.readbyqxmd.com/read/29111401/biofilm-production-is-not-associated-with-poor-clinical-outcome-in-485-patients-with-staphylococcus-aureus-bacteremia
#5
María Guembe, Beatriz Alonso, José Lucio, María Jesús Pérez-Granda, Raquel Cruces, Carlos Sánchez-Carrillo, Ana Fernández-Cruz, Emilio Bouza
OBJECTIVE: Staphylococcus aureus biofilm may constitute a major cause of virulence. Our main objective was to analyze whether there was an association between biofilm production and poor outcome in patients with S. aureus bacteremia. METHODS: We studied 485 S. aureus strains isolated from the blood of patients with bacteremia from 2012 to 2015. We assessed in vitro biomass production using the crystal violet assay (CV) and metabolic activity using the tetrazolium salt assay (XTT)...
October 27, 2017: Clinical Microbiology and Infection
https://www.readbyqxmd.com/read/29109373/development-of-a-lethal-intranasal-exposure-model-of-ebola-virus-in-the-cynomolgus-macaque
#6
Kendra J Alfson, Laura E Avena, Gabriella Worwa, Ricardo Carrion, Anthony Griffiths
Ebola virus (EBOV) is a filovirus that can cause Ebola virus disease (EVD). No approved vaccines or therapies exist for filovirus infections, despite an urgent need. The development and testing of effective countermeasures against EBOV requires use of animal models and a thorough understanding of how the model aligns with EVD in humans. The majority of published studies report outcomes of parenteral exposures for emulating needle stick transmission. However, based on data from EVD outbreaks, close contact exposures to infected bodily fluid seems to be one of the primary routes of EBOV transmission...
October 29, 2017: Viruses
https://www.readbyqxmd.com/read/29073151/inhalation-of-volatile-anesthetics-via-a-laryngeal-mask-is-associated-with-lower-incidence-of-intraoperative-awareness-in-non-critically-ill-patients
#7
Pei-Jen Kuo, Chia-Ling Lee, Jen-Huang Wang, Shiu-Ying Hsieh, Shian-Che Huang, Chen-Fuh Lam
BACKGROUND: Increased incidence of intraoperative awareness was reported in critically ill patients during major operations, particularly under total intravenous (TIVA) or endotracheal general anesthesia (ETGA). However, the incidence and effect of anesthesia techniques on awareness in generally healthy, non-critically ill patients during operations have yet to receive significant attention. METHODS AND RESULTS: This retrospective matched case-control study was conducted between January 2009 to December 2014...
2017: PloS One
https://www.readbyqxmd.com/read/29068977/endotracheal-intubation-in-elective-cervical-surgery-a-randomized-controlled-assessor-blinded-study
#8
RANDOMIZED CONTROLLED TRIAL
Hongna Fan, Huijuan Cao, Yingjie Sun, Keyan Chen, Yugang Diao, Nan Zhou, Guoquan Yao, Jin Zhou, Tiezheng Zhang
BACKGROUND: We compared the effectiveness and safety of endotracheal intubation using the GlideScope (GS) video laryngoscope, CTrach laryngeal mask airway (LMA), or Shikani optical stylet rigid laryngoscope (SOS) during elective cervical surgery. METHODS: Forty-five patients undergoing elective cervical surgery were randomly and equally assigned to endotracheal intubation via GS, LMA, or SOS airway management. RESULTS: Endotracheal intubation was successfully completed in all patients...
October 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29067047/the-use-of-flexible-laryngeal-mask-airway-for-adenoidectomies-an-experience-of-814paediatric-patients
#9
Ozlem Ozmete, Mesut Sener, Esra Caliskan, Meltem Kipri, Anis Aribogan
OBJECTIVE: To assess flexible laryngeal mask airway (F-LMA) use during pediatric adenoidectomies in terms of patient safety, comfort, complication rates and surgeon satisfaction levels. METHODS: Patients who had undergone an elective adenoidectomy after receiving general anesthesia using F-LMA from June 2012 to November 2015 were included. Patients' demographics and the incidence of perioperative complications were investigated. The surgeon's satisfaction level was also evaluated by questionnaire...
July 2017: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/29046894/fatty-acid-mimetic-micelles-for-dual-delivery-of-antigens-and-imidazoquinoline-adjuvants
#10
Sema Sevimli, Frances C Knight, Pavlo Gilchuk, Sebastian Joyce, John T Wilson
Vaccine design has undergone a shift towards the use of purified protein subunit vaccines, which offer increased safety and greater control over antigen specificity, but at the expense of immunogenicity. Here we report the development of a new polymer-based vaccine delivery platform engineered to enhance immunity through the co-delivery of protein antigens and the Toll-like receptor 7 (TLR7) agonist imiquimod (IMQ). Owing to the preferential solubility of IMQ in fatty acids, a series of block copolymer micelles with a fatty acid-mimetic core comprising lauryl methacrylate (LMA) and methacrylic acid (MAA), and a poly(ethylene glycol) methyl ether methacrylate (PEGMA) corona decorated with pyridyl disulfide ethyl methacrylate (PDSM) moieties for antigen conjugation were synthesized via reversible addition-fragmentation chain transfer (RAFT) polymerization...
February 13, 2017: ACS Biomaterials Science & Engineering
https://www.readbyqxmd.com/read/29045961/-effects-of-recent-upper-respiratory-tract-infections-on-incidence-of-the-perioperative-respiratory-adverse-events-in-children-a-prospective-cohort-study
#11
C Q Li, D X Wang, T Cheng, X Y Zheng
OBJECTIVE: To investigate the effects of the recent upper respiratory tract infections (URI) on the incidence of perioperative respiratory adverse events in children scheduled to undergo general anesthesia and elective surgery. METHODS: In the study, 232 children undergoing general anesthesia with laryngeal mask airway (LMA) for elective ophthalmic surgeries at Peking University First Hospital, Beijing, China, from Nov. 1, 2015 to May 10, 2016 were enrolled. On the day of the surgery, the parents of the children were preoperatively asked to fill out a questionnaire regarding the baseline characteristics and medical history of the children, including gender, age, height, weight, history of URI within the last 2 weeks before anesthesia, history of premature, long-term passive smoking exposure, habitual sleep snoring, and history of asthma...
October 18, 2017: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
https://www.readbyqxmd.com/read/29041644/thermally-induced-mode-loss-evolution-in-the-coiled-ytterbium-doped-large-mode-area-fiber
#12
Lingchao Kong, Jinyong Leng, Pu Zhou, Zongfu Jiang
We propose a model to calculate the thermally induced mode loss evolution in the coiled ytterbium doped large mode area (LMA) fiber. The mode loss evolution in the coiled conventional step index LMA 20/400 fiber is investigated. Meanwhile, a model of fiber amplifier considering thermally induced mode loss evolution is established. The higher order mode (HOM) suppression between a co-pumping scheme and counter-pumping scheme under the heat load are compared. The simulation shows that the HOM loss decreases quasi-exponentially with the heat load and the bending radius of the ytterbium doped fiber (YDF) should be optimized according to the heat load to achieve effectively single mode operation...
September 18, 2017: Optics Express
https://www.readbyqxmd.com/read/29041484/large-mode-area-inverse-index-fiber-with-a-graded-index-profile-for-high-power-single-mode-operation
#13
Hyun Su Kim, Seongwoo Yoo
We propose a new gain fiber structure with an inverse index profile for high power amplification of a Gaussian single mode beam. A large mode area (LMA) design can be fulfilled with the inverse index profile by implementing a graded index in the depressed core. We numerically show that the proposed gain fiber can guide a single mode Gaussian beam with a large beam area and amplify the beam to a kW level output power.
September 4, 2017: Optics Express
https://www.readbyqxmd.com/read/29041258/manipulating-refractive-index-homogeneity-and-spectroscopy-of-yb-3-doped-silica-core-glass-towards-high-power-large-mode-area-photonic-crystal-fiber-lasers
#14
Fan Wang, Lili Hu, Wenbin Xu, Meng Wang, Suya Feng, Jinjun Ren, Lei Zhang, Danping Chen, Nadège Ollier, Guojun Gao, Chunlei Yu, Shikai Wang
Output power scaling of single mode large mode area (LMA) photonic crystal fiber (PCF) amplifiers urgently requires the low refractive index of Yb(3+)-doped silica glasses whilst maintaining high optical homogeneity. In this paper, we report on a promising alternative Yb(3+)/Al(3+)/F(-)/P(5+)-co-doped silica core-glass (YAFP), which is prepared by modified sol-gel method developed by our group and highly suitable for fabricating high power LMA PCF amplifiers. By controlling the doping combinations of Al(3+)/F(-)/P(5+) in Yb(3+)-doped silica glass,it not only ensures low refractive index (RI) but also maintains the excellent optical homogeneity and spectroscopic properties of Yb(3+)...
October 16, 2017: Optics Express
https://www.readbyqxmd.com/read/29033724/comparison-of-laryngeal-tube-suction-ii-and-proseal-lma%C3%A2-in-pediatric-patients-undergoing-elective-surgery
#15
Saurabh Chandrakar, Deepak Kumar Sreevastava, Sidharth Bhasin, Mridul Dhar
BACKGROUND: Supraglottic airway devices now have an established place in pediatric anesthesia practice. The laryngeal tube suction (LTS) II, a recent revision of the LTS, has very few studies evaluating its use in pediatric patients. The aim of this study was to compare insertion and ventilation profiles of the LTS-II size 2 and the ProSeal™ Laryngeal Mask Airway (PLMA) size 2 in pediatric patients undergoing elective surgeries. MATERIALS AND METHODS: A randomized prospective study was conducted in 100 children aged 2-5 years between 12 and 25 kg weight, of the American Society of Anesthesiologists physical status I and II scheduled for routine elective surgeries of <90 min duration...
October 2017: Saudi Journal of Anaesthesia
https://www.readbyqxmd.com/read/29033717/comparison-of-oropharyngeal-leak-pressure-of-air-q%C3%A2-i-gel%C3%A2-and-laryngeal-mask-airway-supreme%C3%A2-in-adult-patients-during-general-anesthesia-a-randomized-controlled-trial
#16
Srinath Damodaran, Sameer Sethi, Surender Kumar Malhotra, Tanvir Samra, Souvik Maitra, Vikas Saini
STUDY OBJECTIVE: Various randomized controlled trials and a meta-analysis have compared i-gel™ and laryngeal mask airway Supreme™ (LMA-S™) in adult patients and found that both the devices provided equivalent oropharyngeal leak pressure (OLP). However, no randomized controlled trial has compared air-Q™ with i-gel™ and LMA-S™ in adult patient. Hence, we designed this study to compare air-Q™ with LMA-S™ and i-gel™ in adult patients. MATERIALS AND METHODS: A total of 75 adult patients of the American Society of Anesthesiologists physical status I/II of both sexes, between 18 and 60 years, were included in this prospective randomized controlled trial conducted in a tertiary care center...
October 2017: Saudi Journal of Anaesthesia
https://www.readbyqxmd.com/read/28989912/effect-of-low-dose-atracurium-on-laryngeal-mask-airway-insertion-conditions-a-randomized-double-blind-clinical-trial
#17
Karim Nasseri
BACKGROUND: The amount of sedation and muscle relaxation of the jaw may have an impact on complications caused by laryngeal mask airway (LMA). The aim of this study is to evaluate the effect of low-dose Atracurium on conditions of insertion, complications, and hemodynamic responses to LMA insertion following induction of anesthesia with propofol, in patients undergoing cataract surgery. PATIENTS AND METHODS: In this double-blind randomized clinical trial study, 60 patients were randomly divided into two groups...
2017: Advanced Biomedical Research
https://www.readbyqxmd.com/read/28984089/airway-management-with-fastrach-laryngeal-mask-versus-spritztube-a-prospective-randomised-manikin-based-study
#18
Silvia DE Rosa, Fiorenza Ferrari, Stefano Carboni Checcacci, Alessandro Rigobello, Paolo Gennaro, Daniele DE Luca, Mirco Primadei, Federico Politi, Adriano Pellizzari, Raffaele Bonato
BACKGROUND: A new promising device, the Spritztube (ST), was developed combining the ability to perform both supraglottic ventilation and orotracheal fibreoptic intubation using the same device, allowing an easy passage from supraglottic ventilation to tracheal ventilation avoiding apnea. The present study aims to compare the speed and the subjective ease of in- sertion of the novel tracheal tube (Spritztube ®) compared to the intubating laryngeal mask airway FastrachTM [FT-LMA] in a simulation environment...
October 4, 2017: Minerva Anestesiologica
https://www.readbyqxmd.com/read/28981578/potassium-not-lepidimoide-is-the-principal-allelochemical-of-cress-seed-exudate-that-promotes-amaranth-hypocotyl-elongation
#19
Stephen C Fry
Background and Aims: Imbibed cress ( Lepidium sativum L.) seeds exude 'allelochemicals' that promote excessive hypocotyl elongation and inhibit root growth in neighbouring competitors, e.g. amaranth ( Amaranthus caudatus L.) seedlings. The major hypocotyl promoter has recently been shown not to be the previously suggested acidic disaccharide, lepidimoic acid (LMA), a fragment of the pectic polysaccharide domain rhamnogalacturonan-I. The nature of the hypocotyl promoter has now been re-assessed...
October 17, 2017: Annals of Botany
https://www.readbyqxmd.com/read/28960037/myocardial-assessment-in-school-aged-children-with-past-kawasaki-disease
#20
Heeyoung Lee, Jaeeun Shin, Lucy Eun
Coronary artery involvement remains the most important complication with Kawasaki disease (KD). Additional myocardial injury can be caused by inflammatory response and ischemic event. However, the long-term outcome of myocardial function has not been fully known in KD. The purpose of this study is to evaluate myocardial function in school-aged children who had the past history of KD. Sixty-seven children in the second grade of elementary schools, who had the past history of KD, were included. Echocardiographic measurements of each coronary artery and myocardial function were obtained as the long-term follow-up data, and compared with the baseline data at the time of initial presentation of KD...
November 2017: Journal of Korean Medical Science
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