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https://www.readbyqxmd.com/read/29775413/human-cerebral-collateral-arteriole-function-in-normal-cognition-mild-cognitive-impairment-and-dementia-subjects
#1
Raymond Q Migrino, Seth Truran, Nina Karamanova, Geidy Serrano, Calvin Madrigal, Hannah A Davies, Jillian Madine, Peter Reaven, Thomas G Beach
Clinical and preclinical studies suggest a link between cardiovascular disease and dementia disorders but the role of collateral brain circulation in cognitive dysfunction remains unknown. We aim to test the hypothesis that leptomeningeal arteriole (LMA) function and response to metabolic stressors differ among dementia, mild cognitive impairment (MCI) and normal cognition (CN) subjects. Following rapid autopsy, LMA were isolated from CN (N=10), MCI (N=12) or dementia subjects (N=42, Alzheimer's disease [AD], vascular dementia [VaD], or Other Dementia) and endothelial and smooth muscle-dependent function were measured at baseline and following exposure to β-amyloid (Aβ42 2 μM), palmitic acid (PA 150 μM) or medin (5μM) and compared...
May 18, 2018: American Journal of Physiology. Heart and Circulatory Physiology
https://www.readbyqxmd.com/read/29766224/stable-and-enriched-cenarchaeum-symbiosum-and-uncultured-betaproteobacteria-hf1-in-the-microbiome-of-the-mediterranean-sponge-haliclona-fulva-demospongiae-haplosclerida
#2
Erika García-Bonilla, Pedro F B Brandão, Thierry Pérez, Howard Junca
Sponges harbor characteristic microbiomes derived from symbiotic relationships shaping their lifestyle and survival. Haliclona fulva is encrusting marine sponge species dwelling in coralligenous accretions or semidark caves of the Mediterranean Sea and the near Atlantic Ocean. In this work, we characterized the abundance and core microbial community composition found in specimens of H. fulva by means of electron microscopy and 16S amplicon Illumina sequencing. We provide evidence of its low microbial abundance (LMA) nature...
May 15, 2018: Microbial Ecology
https://www.readbyqxmd.com/read/29759775/real-time-x-mri-guided-left-ventricular-lead-implantation-for-targeted-delivery-of-cardiac-resynchronization-therapy
#3
Jonathan M Behar, Peter Mountney, Daniel Toth, Sabrina Reiml, Maria Panayiotou, Alexander Brost, Bernhard Fahn, Rashed Karim, Simon Claridge, Tom Jackson, Ben Sieniewicz, Nik Patel, Mark O'Neill, Reza Razavi, Kawal Rhode, Christopher Aldo Rinaldi
OBJECTIVES: This study sought to test the feasibility of a purpose-built, integrated software platform to process, analyze, and overlay cardiac magnetic resonance (CMR) data in real time within a combined cardiac catheter laboratory and magnetic resonance imaging scanner suite (X-MRI) to guide left ventricular (LV) lead implantation. BACKGROUND: Suboptimal LV lead position is a major determinant of poor cardiac resynchronization therapy (CRT) response, and the optimal site is highly patient specific...
August 2017: JACC. Clinical Electrophysiology
https://www.readbyqxmd.com/read/29756057/clinical-application-of-limiting-laryngeal-mask-airway-cuff-pressures-utilizing-inflating-syringe-intrinsic-recoil
#4
David M Corda, Christopher B Robards, Mark J Rice, Timothy E Morey, Nikolaus Gravenstein, Terrie Vasilopoulos, Sorin J Brull
Background: Overinflation of the laryngeal mask airway (LMA) cuff may cause many of the complications associated with the use of the LMA. There is no clinically acceptable (cost effective and practical) method to ensure cuff pressure is maintained below the manufacturer's recommended maximum value of 60 cm H2 O (44 mmHg). We studied the use of the intrinsic recoil of the LMA inflating syringe as an effective and practical way to limit cuff pressures at or below the manufacturer's recommended values...
April 2018: Romanian Journal of Anaesthesia and Intensive Care
https://www.readbyqxmd.com/read/29755138/modulation-of-surface-initiated-atrp-by-confinement-mechanism-and-applications
#5
Edmondo M Benetti, Chengjun Kang, Joydeb Mandal, Mohammad Divandari, Nicholas D Spencer
The mechanism of surface-initiated atom transfer polymerization (SI-ATRP) of methacrylates in confined volumes is systematically investigated by finely tuning the distance between a grafting surface and an inert plane by means of nanosized patterns and micrometer thick foils. The polymers were synthesized from monolayers of photocleavable initiators, which allow the analysis of detached brushes by size-exclusion chromatography (SEC). Compared to brushes synthesized under "open" polymerization mixtures, nearly a 4-fold increase in brush molar mass was recorded when SI-ATRP was performed within highly confined reaction volumes...
August 8, 2017: Macromolecules
https://www.readbyqxmd.com/read/29751056/sex-and-trait-anxiety-differences-in-psychological-stress-are-modified-by-environment
#6
James Liu, John Scira, Simone Donaldson, Nina Kajiji, Gordon H Dash, S Tiffany Donaldson
Evidence-based research has revealed how physiological and emotional responses to acute stress are adaptive. However, under conditions of unpredictable or protracted stress, health and drug vulnerability can be compromised. In this study, we examined anxiety-like behavioral responses of 4th generation adolescent male and female Long Evans rats selectively bred for high (HAn) and low (LAn) anxiety-like behavior when housed in an isolated environment (IE) versus a social environment (SE). After 35 days in IE or SE, animals were tested in the elevated plus maze (EPM), injected with amphetamine (AMPH: 0...
May 8, 2018: Neuroscience
https://www.readbyqxmd.com/read/29749630/divergent-trait-and-environment-relationships-among-parallel-radiations-in-pelargonium-geraniaceae-a-role-for-evolutionary-legacy
#7
Timothy E Moore, Carl D Schlichting, Matthew E Aiello-Lammens, Kerri Mocko, Cynthia S Jones
Functional traits in closely related lineages are expected to vary similarly along common environmental gradients as a result of shared evolutionary and biogeographic history, or legacy effects, and as a result of biophysical tradeoffs in construction. We test these predictions in Pelargonium, a relatively recent evolutionary radiation. Bayesian phylogenetic mixed effects models assessed, at the subclade level, associations between plant height, leaf area, leaf nitrogen content and leaf mass per area (LMA), and five environmental variables capturing temperature and rainfall gradients across the Greater Cape Floristic Region of South Africa...
May 11, 2018: New Phytologist
https://www.readbyqxmd.com/read/29743619/co-regulation-of-photosynthetic-capacity-by-nitrogen-phosphorus-and-magnesium-in-a-subtropical-karst-forest-in-china
#8
Jing Wang, Xuefa Wen, Xinyu Zhang, Shenggong Li, Da-Yong Zhang
Leaf photosynthetic capacity is mainly constrained by nitrogen (N) and phosphorus (P). Little attention has been given to the photosynthetic capacity of mature forests with high calcium (Ca) and magnesium (Mg) in the Karst critical zone. We measured light-saturated net photosynthesis (Asat ), photosynthetic capacity (maximum carboxylation rate [Vcmax ], and maximum electron transport rate [Jmax ]) as well as leaf nutrient contents (N, P, Ca, Mg, potassium [K], and sodium [Na]), leaf mass per area (LMA), and leaf thickness (LT) in 63 dominant plants in a mature subtropical forest in the Karst critical zone in southwestern China...
May 9, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29737389/4d-asl-based-mr-angiography-for-visualization-of-distal-arteries-and-leptomeningeal-collateral-vessels-in-moyamoya-disease-a-comparison-of-techniques
#9
Osamu Togao, Akio Hiwatashi, Makoto Obara, Koji Yamashita, Daichi Momosaka, Ataru Nishimura, Koichi Arimura, Nobuhiro Hata, Koji Yoshimoto, Koji Iihara, Marc Van Cauteren, Hiroshi Honda
OBJECTIVES: To evaluate the performance of four-dimensional pseudo-continuous arterial spin labeling (4D-pCASL)-based angiography using CENTRA-keyhole and view sharing (4D-PACK) in the visualization of flow dynamics in distal cerebral arteries and leptomeningeal anastomosis (LMA) collaterals in moyamoya disease in comparison with contrast inherent inflow-enhanced multiphase angiography (CINEMA), with reference to digital subtraction angiography (DSA). METHODS: Thirty-two cerebral hemispheres from 19 patients with moyamoya disease (mean age, 29...
May 8, 2018: European Radiology
https://www.readbyqxmd.com/read/29726946/influence-of-feeding-thermally-peroxidized-soybean-oil-to-finishing-pigs-on-carcass-characteristics-loin-quality-and-shelf-life-of-loin-chops
#10
M F Overholt, G D Kim, D D Boler, B J Kerr, A C Dilger
The objective of this study was to evaluate the effect of feeding soybean oil (SO) with varying levels of peroxidation on carcass traits and shelf life of loins. Fifty-six barrows were randomly assigned to 1 of 4 diets containing 10% fresh SO (22.5°C) or thermally processed SO (45°C for 288 h, 90°C for 72 h, or 180°C for 6 h), each infused with air at a rate of 15L/min. Individually housed pigs were provided ad libitum access to feed for 81 d. At 82 d pigs were slaughtered and hot carcass weight (HCW) and liver weights were recorded...
May 3, 2018: Journal of Animal Science
https://www.readbyqxmd.com/read/29724857/divergent-drivers-of-leaf-trait-variation-within-species-among-species-and-among-functional-groups
#11
Jeanne L D Osnas, Masatoshi Katabuchi, Kaoru Kitajima, S Joseph Wright, Peter B Reich, Sunshine A Van Bael, Nathan J B Kraft, Mirna J Samaniego, Stephen W Pacala, Jeremy W Lichstein
Understanding variation in leaf functional traits-including rates of photosynthesis and respiration and concentrations of nitrogen and phosphorus-is a fundamental challenge in plant ecophysiology. When expressed per unit leaf area, these traits typically increase with leaf mass per area ( LMA ) within species but are roughly independent of LMA across the global flora. LMA is determined by mass components with different biological functions, including photosynthetic mass that largely determines metabolic rates and contains most nitrogen and phosphorus, and structural mass that affects toughness and leaf lifespan ( LL )...
May 3, 2018: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/29722013/effect-of-shading-intensity-on-morphological-and-color-traits-and-chemical-components-of-new-tea-camellia-sinensis-l-shoots-under-direct-covering-cultivation
#12
Tomohito Sano, Hideki Horie, Akiko Matsunaga, Yuhei Hirono
BACKGROUND: Use of covering cultivation to shade tea (Camellia sinensis L.) trees to produce high-quality, high-priced green tea has recently increased in Japan. Knowledge of shading effects on morphological and color traits, and chemical components of new tea shoots is important for product quality and productivity. We assessed these traits of tea shoots and their relationships under covering cultivation of various radiation intensities. RESULTS: Leaf thickness, LMA (leaf mass per area), and leaf density of new tea leaves were smaller under covering culture than under open-field culture...
May 2, 2018: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/29714527/comparison-of-the-force-required-for-dislodgement-between-secured-and-unsecured-airways
#13
Curtis Davenport, Christian Martin-Gill, Henry E Wang, James Mayrose, Jestin N Carlson
INTRODUCTION: Airway device placement and maintenance are of utmost importance when managing critically ill patients. The best method to secure airway devices is currently unknown. STUDY OBJECTIVE: We sought to determine the force required to dislodge 4 types of airways with and without airway securing devices. METHODS: We performed a prospective study using 4 commonly used airway devices (endotracheal tube [ETT], laryngeal mask airway [LMA], King laryngeal tube [King], and iGel) performed on 5 different mannequin models...
May 1, 2018: Prehospital Emergency Care
https://www.readbyqxmd.com/read/29707376/is-laryngeal-mask-airway-general-anesthesia-feasible-for-minimally-invasive-esophagectomy
#14
Rui-Xiang Zhang, Yin Li, Xian-Ben Liu, Xi-Hua Lu, Hai-Bo Sun, Zong-Fei Wang, Shi-Lei Liu, Yan Zheng, Xiao-Fei Liu, Xiu-Xia Wu
Minimally invasive esophagectomy (MIE) has been identified as an oncological method with lower mortality and morbidity. This procedure is usually performed under general anesthesia using double endotracheal tube intubation and one-lung ventilation for a good visualization like other video-assisted thoracoscopic surgery (VATS). However, it is difficult to differentiate weather the postoperative hoarseness is caused by intubation or by recurrent laryngeal nerve injury during operation, and some complications related to intubation also are the focus of thoracic surgeons...
March 2018: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29705658/laminarin-improves-developmental-competence-of-porcine-early-stage-embryos-by-inhibiting-oxidative-stress
#15
Hao Jiang, Shuang Liang, Xue-Rui Yao, Yong-Xun Jin, Xing-Hui Shen, Bao Yuan, Jia-Bao Zhang, Nam-Hyung Kim
Laminarin (LMA), a β-glucan mixture with good biocompatibility, improves the growth performance and immune response when used as food additives and nutraceuticals. The aim of the present research was to explore the effects of LMA on porcine early stage embryo development, as well as the underlying mechanisms. The results showed that the developmental competence of porcine early stage embryos was dramatically improved after LMA supplementation during the in vitro culture period. The presence of 20 μg/mL LMA during the in vitro culture period significantly improved cleavage rate, blastocyst formation rates, hatching rate, and total cell number in the blastocyst compared to that in the control group...
April 23, 2018: Theriogenology
https://www.readbyqxmd.com/read/29686691/evaluation-of-morpho-physiological-traits-adjustment-of-prosopis-tamarugo-under-long-term-groundwater-depletion-in-the-hyper-arid-atacama-desert
#16
Marco Garrido, Herman Silva, Nicolás Franck, Jorge Arenas, Edmundo Acevedo
Water extraction from the underground aquifers of the Pampa del Tamarugal (Atacama Desert, Chile) reduced the growing area of Prosopis tamarugo , a strict phreatic species endemic to northern Chile. The objective of this work was to evaluate the effect of various architectural and morpho-physiological traits adjustment of P. tamarugo subjected to three groundwater depletion intervals (GWDr): <1 m (control), 1-4 m and 6-9 m. The traits were evaluated at three levels, plant [height, trunk cross-section area, leaf fraction ( f GCC), and crown size], organ [length of internodes, leaf mass per unit area (LMA), leaflet mass and area], and tissue level [wood density (WD), leaf 13 C, 18 O isotope composition (δ), and intrinsic water use efficiency (iWUE)]...
2018: Frontiers in Plant Science
https://www.readbyqxmd.com/read/29676468/cell-wall-properties-in-oryza-sativa-influence-mesophyll-co-2-conductance
#17
Patrícia V Ellsworth, Patrick Z Ellsworth, Nuria K Koteyeva, Asaph B Cousins
Diffusion of CO2 from the leaf intercellular air space to the site of carboxylation (gm ) is a potential trait for increasing net rates of CO2 assimilation (Anet ), photosynthetic efficiency, and crop productivity. Leaf anatomy plays a key role in this process; however, there are few investigations into how cell wall properties impact gm and Anet . Online carbon isotope discrimination was used to determine gm and Anet in Oryza sativa wild-type (WT) plants and mutants with disruptions in cell wall mixed-linkage glucan (MLG) production (CslF6 knockouts) under high- and low-light growth conditions...
April 20, 2018: New Phytologist
https://www.readbyqxmd.com/read/29669076/effect-of-lower-energy-higher-fiber-diets-on-pigs-divergently-selected-for-residual-feed-intake-when-fed-higher-energy-lower-fiber-diets
#18
E D Mauch, J M Young, N V L Serão, W L Hsu, J F Patience, B J Kerr, T E Weber, N K Gabler, J C M Dekkers
Residual feed intake (RFI) is the difference between observed and predicted feed intake of an animal, based on growth and maintenance requirements. In Yorkshire pigs, divergent selection for increased (Low RFI) and decreased (High RFI) RFI was carried out over 10 generations (G) while feeding a corn- and soybean-meal-based, higher-energy, lower-fiber (HELF) diet. In G8 to G10, representing 4 replicates, barrows and gilts (n = 649) of the RFI lines were fed the HELF diet and a diet incorporating coproducts that were lower in energy and higher in dietary fiber (LEHF)...
April 14, 2018: Journal of Animal Science
https://www.readbyqxmd.com/read/29650147/source-sink-relations-of-sunflower-plants-as-affected-by-a-parasite-modifies-carbon-allocations-and-leaf-traits
#19
Shahar Pincovici, Amnon Cochavi, Arnon Karnieli, Jhonathan Ephrath, Shimon Rachmilevitch
Sunflower broomrape (Orobanche cumana) is a root holoparasitic plant causing major damage to sunflower (Helianthus annuus L.). Parasite infection initiates source-sink relations between the parasite (sink) and the host (source), allocating carbohydrates, water and nutrients to the parasite. The primary aim of the current study was to explore responses of sunflower to broomrape parasitism, specifically to examine alternations in leaf area, leaf mass per area (LMA), mesophyll structure and root hydraulic conductivity...
June 2018: Plant Science: An International Journal of Experimental Plant Biology
https://www.readbyqxmd.com/read/29644401/-skill-retention-using-extraglottic-airways-in-out-of-hospital-emergencies-efficacy-and-long-term-results-of-simulator-based-medical-education-a-prospective-follow-up-study
#20
V Mann, F Limberg, S T W Mann, S Little, M Müller, M Sander, R Röhrig
OBJECTIVE: For emergency medicine personnel (EMP), there is little evidence concerning the adequate timing for refresher courses to maintain routine in the application of extraglottic airways. The aim of this study was to evaluate the efficacy and long-term results of a simulator-based education concept teaching the basic airway management skills with extraglottic airways for EMP and also to draw conclusions concerning the adequate time interval for refresher courses. METHODS: By use of an explorative, prospective simulator-study with nonphysician EMP, airway management skills using the Larynxmaske Supreme® (LMA‑S) after an introduction lecture were examined...
April 11, 2018: Medizinische Klinik, Intensivmedizin und Notfallmedizin
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