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https://www.readbyqxmd.com/read/27913009/quantitative-changes-in-late-gadolinium-enhancement-at-cardiac-magnetic-resonance-in-the-early-phase-of-acute-myocarditis
#1
Enrico Ammirati, Francesco Moroni, Paola Sormani, Angelica Peritore, Angela Milazzo, Giuseppina Quattrocchi, Manlio Cipriani, Fabrizio Oliva, Cristina Giannattasio, Maria Frigerio, Alberto Roghi, Paolo G Camici, Patrizia Pedrotti
BACKGROUND: The presence of late gadolinium enhancement (LGE) at cardiac magnetic resonance (CMR) has diagnostic and prognostic value in patients with acute myocarditis (AM). Aim of our study was to quantify the changes in LGE extension (LGE%) early after AM and evaluate its relations with biventricular function and morphology. METHODS: We investigated 76 consecutive patients with AM (acute onset of chest pain/heart failure/ventricular arrhythmias not explained by other causes, and raised troponin) that met CMR criteria based on myocardial oedema at T2-weighted images and LGE on post-contrast images at median time of 6days from onset of symptoms...
November 23, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/27912983/hypertrophic-obstructive-cardiomyopathy
#2
REVIEW
Josef Veselka, Nandan S Anavekar, Philippe Charron
Hypertrophic obstructive cardiomyopathy is an inherited myocardial disease defined by cardiac hypertrophy (wall thickness ≥15 mm) that is not explained by abnormal loading conditions, and left ventricular obstruction greater than or equal to 30 mm Hg. Typical symptoms include dyspnoea, chest pain, palpitations, and syncope. The diagnosis is usually suspected on clinical examination and confirmed by imaging. Some patients are at increased risk of sudden cardiac death, heart failure, and atrial fibrillation...
November 29, 2016: Lancet
https://www.readbyqxmd.com/read/27909540/association-between-left-atrial-compression-and-atrial-fibrillation-a-case-presentation-and-a-short-review-of-literature
#3
Niloy Ahmed Md, Morales-Mangual Carlos Md, Gunsburg Moshe Md, Rosen Yitzhak Md
This case report describes a patient who developed palpitations and chest pain and was found to be in atrial fibrillation, which was likely due to the presence of an extra-cardiac mass. This was compressing the left atrium. The mass was related to small cell carcinoma, which decreased significantly in size after chemotherapy. Resolution of the atrial fibrillation correlated temporally with reduction in the size of the mass and alleviation of the left atrial compression.
August 2016: Journal of Atrial Fibrillation
https://www.readbyqxmd.com/read/27909290/highly-sensitive-detection-of-minimal-cardiac-ischemia-using-positron-emission-tomography-imaging-of-activated-platelets
#4
Melanie Ziegler, Karen Alt, Brett M Paterson, Peter Kanellakis, Alex Bobik, Paul S Donnelly, Christoph E Hagemeyer, Karlheinz Peter
A reliable method for the diagnosis of minimal cardiac ischemia would meet a strong demand for the sensitive diagnosis of coronary artery disease in cardiac stress testing and risk stratification in patients with chest pain but unremarkable ECGs and biomarkers. We hypothesized that platelets accumulate early on in ischemic myocardium and a newly developed technology of non-invasive molecular PET imaging of activated platelets can thus detect minimal degrees of myocardial ischemia. To induce different degrees of minimal cardiac ischemia, the left anterior descending artery (LAD) was ligated for 10, 20 or 60 min...
December 2, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27907878/ultrasound-in-cardiac-trauma
#5
Theodosios Saranteas, Andreas F Mavrogenis, Christina Mandila, John Poularas, Fotios Panou
In the perioperative period, the emergency department or the intensive care unit accurate assessment of variable chest pain requires meticulous knowledge, diagnostic skills, and suitable usage of various diagnostic modalities. In addition, in polytrauma patients, cardiac injury including aortic dissection, pulmonary embolism, acute myocardial infarction, and pericardial effusion should be immediately revealed and treated. In these patients, arrhythmias, mainly tachycardia, cardiac murmurs, or hypotension must alert physicians to suspect cardiovascular trauma, which would potentially be life threatening...
November 5, 2016: Journal of Critical Care
https://www.readbyqxmd.com/read/27902153/nurse-led-medicines-monitoring-a-study-examining-the-effects-of-the-west-wales-adverse-drug-reaction-profile
#6
Richard Jones, Christopher Moyle, Sue Jordan
Aim The physical health of people with mental health conditions is often suboptimal, and in many cases this may be related to their prescription medicines. One issue is that patients are monitored inconsistently for adverse drug reactions (ADRs). The aim of this study was to explore whether the nurse-led West Wales Adverse Drug Reaction (WWADR) Profile for Mental Health Medicines could improve recognition and management of ADRs in a crisis resolution home treatment service. Method The WWADR Profile was implemented in addition to usual care, in a one-group 'before and after' comparison study (n=20)...
November 30, 2016: Nursing Standard
https://www.readbyqxmd.com/read/27899427/a-56-year-old-woman-with-breathlessness
#7
Alastair J Moss, Marc R Dweck, Peter D O'Kane
CLINICAL INTRODUCTION: A 56-year-old female with adult-onset asthma was admitted to the cardiology service with intermittent left-sided chest pain and progressive dyspnoea. Twelve months prior to this admission, she had received a course of prednisolone for bilateral anterior uveitis. Physical examination was unremarkable with blood sampling revealing a marked eosinophilia (eosinophil count 17.3×10(9)/L) and a perinuclear antineutrophil cytoplasmic antibody staining pattern on indirect immunofluorescence microscopy (myeloperoxidase antibodies 83 IU/mL)...
November 29, 2016: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/27899132/cardiac-t1-mapping-and-extracellular-volume-ecv-in-clinical-practice-a-comprehensive-review
#8
REVIEW
Philip Haaf, Pankaj Garg, Daniel R Messroghli, David A Broadbent, John P Greenwood, Sven Plein
Cardiovascular Magnetic Resonance is increasingly used to differentiate the aetiology of cardiomyopathies. Late Gadolinium Enhancement (LGE) is the reference standard for non-invasive imaging of myocardial scar and focal fibrosis and is valuable in the differential diagnosis of ischaemic versus non-ischaemic cardiomyopathy. Diffuse fibrosis may go undetected on LGE imaging. Tissue characterisation with parametric mapping methods has the potential to detect and quantify both focal and diffuse alterations in myocardial structure not assessable by LGE...
November 30, 2016: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/27899069/gastric-dilatation-and-intestinal-obstruction-mimicking-acute-coronary-syndrome-with-dynamic-electrocardiographic-changes
#9
H M M T B Herath, Anne Thushara Matthias, B S D P Keragala, W A E Udeshika, Aruna Kulatunga
BACKGROUND: ST elevation myocardial infarction is a medical emergency and the electrocardiogram is a part of the mainstay in the initial diagnosis. A variety of non-cardiac conditions have been known to mimic the electrocardiographic changes seen in acute coronary syndrome. We present a patient presenting with acute partial intestinal obstruction causing gastric distension and intestinal dilatation who also had dynamic electrocardiographic changes, mimicking anterior ST elevation myocardial infarction...
November 29, 2016: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/27895882/primary-pleural-synovial-sarcoma-with-metastatic-cardiac-involvement-a-case-report
#10
Ji-Hye Won, Susie Chin, Jai Soung Park, Sang Hyun Paik, Heon Lee, Jang Gyu Cha, Hwa Kyoon Shin, Eun Suk Koh
Primary pleuropulmonary synovial sarcomas are rare soft tissue malignancies; combined metastatic involvement of the heart is extremely rare. In this case report, a 17-year-old female presented with a history of chest pain. Chest radiographs revealed a round mass in the left upper hemithorax, and computed tomography (CT) showed a well-defined heterogeneous enhancing mass abutting the pleura. A core needle biopsy revealed malignant spindle cells. Surgical resection was performed, and a final diagnosis of primary pleural synovial sarcoma, monophasic fibrous type, was made...
October 2016: Iranian Journal of Radiology: a Quarterly Journal Published By the Iranian Radiological Society
https://www.readbyqxmd.com/read/27894070/the-strategy-study-stress-cardiac-magnetic-resonance-versus-computed-tomography-coronary-angiography-for-the-management-of-symptomatic-revascularized-patients-resources-and-outcomes-impact
#11
Gianluca Pontone, Daniele Andreini, Andrea I Guaricci, Cristina Rota, Marco Guglielmo, Saima Mushtaq, Andrea Baggiano, Virginia Beltrama, Laura Fusini, Anna Solbiati, Chiara Segurini, Edoardo Conte, Paola Gripari, Andrea Annoni, Alberto Formenti, Maria Petulla', Federico Lombardi, Giuseppe Muscogiuri, Antonio L Bartorelli, Mauro Pepi
BACKGROUND: Computed tomography coronary angiography (cTCA) and stress cardiac magnetic resonance (stress-CMR) are suitable tools for diagnosing obstructive coronary artery disease in symptomatic patients with previous history of revascularization. However, performance appraisal of noninvasive tests must take in account the consequent diagnostic testing, invasive procedures, clinical outcomes, radiation exposure, and cumulative costs rather than their diagnostic accuracy only. We aimed to compare an anatomic (cTCA) versus a functional (stress-CMR) strategy in symptomatic patients with previous myocardial revascularization procedures...
October 2016: Circulation. Cardiovascular Imaging
https://www.readbyqxmd.com/read/27891257/melas-syndrome-with-cardiac-involvement-a-multimodality-imaging-approach
#12
Sara Seitun, Laura Massobrio, Anna Rubegni, Claudia Nesti, Margherita Castiglione Morelli, Sara Boccalini, Athena Galletto Pregliasco, Irilda Budaj, Luca Deferrari, Gian Marco Rosa, Fabrizio Montecucco, Alberto Valbusa
A 49-year-old man presented with chest pain, dyspnea, and lactic acidosis. Left ventricular hypertrophy and myocardial fibrosis were detected. The sequencing of mitochondrial genome (mtDNA) revealed the presence of A to G mtDNA point mutation at position 3243 (m.3243A>G) in tRNA(Leu(UUR)) gene. Diagnosis of cardiac involvement in a patient with Mitochondrial Encephalomyopathy, Lactic Acidosis, and Stroke-like episodes syndrome (MELAS) was made. Due to increased risk of sudden cardiac death, cardioverter defibrillator was implanted...
2016: Case Reports in Cardiology
https://www.readbyqxmd.com/read/27890686/cardiac-and-skeletal-muscles-metastases-from-squamous-cell-carcinoma-of-the-bladder-pet-ct-findings
#13
Luis Gorospe, Ernesto García-Santana, Pablo Jane-Soler, María Del Val Gómez-Martínez, Victoria Gómez-Dos-Santos, Isabel García-Gómez-Muriel, Raquel García-Latorre
We describe the PET/CT findings of a patient who underwent a radical cystectomy six months earlier because of a squamous cell carcinoma of the bladder (SCCB) that presented to the ER with chest pain and palpitations. Cardiac catheterization ruled out coronary artery occlusion, but PET/CT showed multiple FDG-avid lesions involving multiple skeletal muscles and the heart, consistent with metastases. A CT-guided biopsy of one skeletal muscle lesion confirmed a metastasis with the same pathologic features as the SCCB...
November 24, 2016: Urology
https://www.readbyqxmd.com/read/27889211/takotsubo-cardiomyopathy-associated-with-epinephrine-use-a-systematic-review-and-meta-analysis
#14
Salik Nazir, Saroj Lohani, Niranjan Tachamo, Sushil Ghimire, Dilli Ram Poudel, Anthony Donato
BACKGROUND: Takotsubo cardiomyopathy is a syndrome of transient cardiac dysfunction that is frequently associated with sudden emotional or physical stress. Epinephrine use has been implicated in precipitating Takotsubo cardiomyopathy in multiple case reports and case series. We sought to systematically review the current English literature on this association. METHODS: We searched relevant articles on Takotsubo cardiomyopathy associated with epinephrine administration and extracted data on demographic characteristics, clinical features, investigations and clinical outcomes...
November 22, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/27887782/ambient-particulate-matter-landscape-fire-smoke-and-emergency-ambulance-dispatches-in-sydney-australia
#15
Farhad Salimi, Sarah B Henderson, Geoffrey G Morgan, Bin Jalaludin, Fay H Johnston
BACKGROUND: Emergency ambulance dispatches (EAD) are a novel outcome for evaluating the public health impacts of air pollution. We assessed the relationships between ambient particulate matter (PM) from all sources, PM from landscape fire smoke (LFS), and EADs likely to be associated with cardiorespiratory problems in the Sydney greater metropolitan region for an 11-year period from 2004 to 2015. METHODS: EAD codes are assigned at the time of the call to emergency services using standard computer assisted algorithms...
November 22, 2016: Environment International
https://www.readbyqxmd.com/read/27873006/feasibility-of-omitting-provocation-test-with-50%C3%A2-%C3%AE-g-of-acetylcholine-in-left-coronary-artery
#16
Yuichi Saito, Hideki Kitahara, Toshihiro Shoji, Satoshi Tokimasa, Takashi Nakayama, Kazumasa Sugimoto, Yoshihide Fujimoto, Yoshio Kobayashi
According to the Japanese Circulation Society guideline of vasospastic angina, incremental doses of acetylcholine (ACh) are prescribed for coronary spasm provocation: 20 and 50 μg for the right coronary artery (RCA), and 20, 50 and 100 μg for the left coronary artery (LCA). However, provocation by low doses of ACh in patients with low vasoreactivity may be less needed, and the requirement of 50 μg of ACh for the LCA in these patients has not been evaluated. In the present study, patients who underwent ACh provocation test for both the RCA and LCA were included...
November 21, 2016: Heart and Vessels
https://www.readbyqxmd.com/read/27869490/congenital-diaphragmatic-hernia-causing-cardiac-arrest-in-a-30-year-old-woman
#17
H J Manson, Y M Goh, P Goldsmith, P Scott, P Turner
Congenital diaphragmatic hernia (CDH) usually presents in infancy with respiratory failure requiring urgent surgical correction. Mortality in this group of patients remains poor and persistent pulmonary hypertension is a significant contributor. It is therefore rare for patients to reach adulthood undiagnosed. CDH is often identified incidentally in adults but when symptoms arise, they relate to the organ involved, and include gastrointestinal symptoms of dyspepsia and obstruction, as well as respiratory complaints such as dyspnoea...
November 21, 2016: Annals of the Royal College of Surgeons of England
https://www.readbyqxmd.com/read/27867587/acute-chest-pain-in-a-triathlete-rupture-of-the-noncoronary-sinus-of-valsalva-into-the-right-ventricle
#18
Ernan Zhu, Ralf Westenfeld, Mareike Gastl, Florian Bönner, Alexander Assmann, Amir M Nia, Malte Kelm, Christian Jung
Sinus of Valsalva (SoV) aneurysm is a rare cardiac disease which can be congenital or acquired. A ruptured SoV aneurysm presents a clinical emergency and can lead to progressively deteriorating heart failure. Therefore, appropriate treatment requires prompt and accurate diagnosis. Most ruptured or nonruptured SoV aneurysms are diagnosed by the means of echocardiography. However, cardiovascular magnetic resonance (CMR) can provide information on precise anatomy and mechanisms due to its excellent soft tissue contrast and high resolution, and thereby allows for optimized preoperative planning of the repair strategy...
October 2016: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/27865485/comparison-of-the-effectiveness-of-stress-echocardiography-versus-myocardial-perfusion-imaging-in-patients-presenting-to-the-emergency-department-with-low-risk-chest-pain
#19
Rhian Davies, Guodong Liu, Christopher Sciamanna, William R Davidson, Douglas L Leslie, Andrew J Foy
The aim of this study was to compare clinically relevant cardiovascular outcomes and downstream resource utilization associated with stress echocardiography (SE) and myocardial perfusion imaging (MPI) in emergency department patients with low-risk chest pain. This was a retrospective analysis of health insurance claims data for a national sample of privately insured patients over the period January 1 to December 31, 2011. Subjects were selected who presented to the emergency department with a primary or secondary diagnosis of chest pain and underwent either SE or MPI...
December 15, 2016: American Journal of Cardiology
https://www.readbyqxmd.com/read/27865194/high-sensitivity-cardiac-troponin-t-levels-in-the-emergency-department-in-patients-with-chest-pain-but-no-myocardial-infarction
#20
Axel C Carlsson, Nadia Bandstein, Andreas Roos, Ola Hammarsten, Martin J Holzmann
BACKGROUND: High-sensitivity cardiac troponin T (hs-cTnT) was recently introduced into clinical practice. The increased sensitivity has decreased the specificity. We aimed to determine the predictors for and prevalence of hs-cTnT levels above the 99th percentile in a stable population of patients without myocardial infarction (MI) who sought medical attention for chest pain in the emergency department. METHODS: We included 11,847 patients with chest pain and at least one hs-cTnT measurement during 2011 and 2012...
November 9, 2016: International Journal of Cardiology
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