Jinho Shin, Hae Young Lee, Wook Jin Chung, Ho Joong Youn, Eun Joo Cho, Ki Chul Sung, Shung Chull Chae, Byung Su Yoo, Chang Gyu Park, Soon-Jun Hong, Taek Jong Hong, Dong-Ju Choi, Jong Won Ha, Young Jo Kim, Young Keun Ahn, Myeong-Chan Cho, Soon Kil Kim, Sungha Park, Il-Suk Sohn, Chong-Jin Kim
OBJECTIVES: The aim of this study was to identify associations between the smoothness index of central SBP (CSBP) and changes of ambulatory carotid femoral pulse wave velocity in response to 20-week treatments with losartan and amlodipine vs. losartan and hydrochlorthiazide combinations. METHODS: For 142 (losartan and hydrochlorthiazide: 72, losartan and hydrochlorthiazide: 70) patients examined with ambulatory central blood pressure (BP) monitoring device, we calculated smoothness indices and trough-to-peak ratios of brachial SBP, CSBP, ambulatory pulse pressure amplification (APPA), ambulatory augmentation index at heart rate 75 beats per minute (AAIx75) and ambulatory carotid femoral pulse wave velocity (AcfPWV)...
August 1, 2019: Journal of Hypertension