Karima Al-Akioui Sanz, Carlos Echecopar Parente, Cristina Ferreras, Marta Menéndez Ribes, Alfonso Navarro, Carmen Mestre, Laura Clares, José Luis Vicario, Antonio Balas, Raquel De Paz, Eduardo López Granados, Elena Sánchez Zapardiel, Carlos Jiménez, María López-Oliva, Esther Ramos, Francisco Hernández-Oliveros, Antonio Pérez-Martínez
BACKGROUND: Immunocompromised patients are susceptible to high-risk opportunistic infections and malignant diseases. Most antiviral and antifungal drugs are quite toxic, relatively ineffective, and induce resistance in the long term. The transfer of pathogen-specific Cytotoxic T-Lymphocytes has shown a minimal toxicity profile and effectiveness in treating Cytomegalovirus, Adenovirus, Epstein - Barr virus, BK Virus and Aspergillus infections, but this therapy have the main limitations of regulatory issues, high cost, and absence of public cell banks...
2023: Frontiers in Medicine