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Axel S Koopman, Idsart Kingma, Gert S Faber, Michiel P de Looze, Jaap H van Dieën
With mechanical loading as the main risk factor for LBP in mind, exoskeletons are designed to reduce the load on the back by taking over a part of the required moment. The present study assessed the effect of a passive exoskeleton on back and abdominal muscle activation, hip and lumbar flexion and on the contribution of both the human and the exoskeleton to the L5/S1 net moment, during static bending at five different hand heights. Two configurations of the exoskeleton (LOW & HIGH) differing in angle-torque characteristics were tested...
November 26, 2018: Journal of Biomechanics
Wenbin Hua, Yukun Zhang, Xinghuo Wu, Yong Gao, Shuai Li, Kun Wang, Xianlin Zeng, Shuhua Yang, Cao Yang
The purpose of this retrospective study was to assess the clinical outcomes of discectomy by using full-endoscopic visualization technique via the interlaminar approach versus the transforaminal approach under general anesthesia in the treatment of L5-S1 disc herniation.Sixty patients with L5-S1 disc herniation were non-randomly recruited and assigned into two groups. One group (thirty patients) underwent discectomy by using full-endoscopic visualization technique via the interlaminar approach under general anesthesia, while the other group (thirty patients) underwent discectomy by using full-endoscopic visualization technique via the transforaminal approach under general anesthesia...
November 2018: Medicine (Baltimore)
Cong Ning, Yuanyi Wang, Feng Xu, Wenjing Zhang, Wei Liu, Zhenshan Lv, Yadong Liu, Changfeng Fu
RATIONALE: The accurate and smooth establishment of a working cannula guarantees rapid and minimally invasive treatment effects using percutaneous endoscopic lumbar discectomy (PELD) for lumbar disc herniation (LDH). With anatomic variations such as a hyperplastic superior articular process (SAP), the conventional transforaminal approach cannot achieve an ideal result. PATIENT CONCERNS: A 48-year-old male patient suffered waist and left lower limb pain, with exacerbation of symptoms after exertion...
November 2018: Medicine (Baltimore)
Abdulaziz A Qurashi, Louise A Rainford, Khalid M Alshamrani, Shane J Foley
The aim of this study was to evaluate how iterative reconstruction can compensate for the noise increase in low radiation dose abdominal computed tomography (CT) technique for large size patients and the general impact of obesity on abdominal organ doses and image quality in CT. An anthropomorphic phantom layered with either none or a single layer of 3-cm- thick circumferential animal fat packs to simulate obese patients was imaged using a 128MDCT scanner. Abdominal protocols (n = 12) were applied using automatic tube current modulation (ATCM) with various quality reference mAs (150, 200, 250 and 300)...
December 1, 2018: Radiation Protection Dosimetry
Danica Cvetković, Vladimir Živković, Slobodan Nikolić
An accident occurred at a construction site and a 27-year-old worker was fatally injured. Equipped with personal protective equipment (helmet and a safety belt), he was standing on an 8-meter-high platform holding a large hose that was attached to a pipe connected to a concrete pump truck. Whilst in use the pipe broke and the hose sent the man flying with force, knocking down the platform railing. Autopsy examination showed that man fell to the ground landing on his head. Prominent Simon's hemorrhages were noted on the L5-S1 and L4-L5 intervertebral discs...
December 1, 2018: Forensic Science, Medicine, and Pathology
Leili Adinehmehr, Sohrab Salimi, Mohammad Azad Majedi, Azadeh Alizadeh, Shahryar Sane
Background: Heat loss and core-to-peripheral redistribution of body heat occur in patients undergoing neuraxial anesthesia resulted to decrease of core temperature and early reach of shivering threshold. Because shivering has deleterious metabolic and cardiovascular effects, it should ideally be prevented by pharmacologic or other means. Tizanidine is an alpha-2 agonist. We evaluated the usefulness of oral tizanidine (TI) and tramadol in preventing of shivering in patients undergoing spinal anesthesia for transurethral resection of the prostate (TURP)...
2018: Advanced Biomedical Research
Ju-Eun Kim, Dae-Jung Choi
Foraminal decompression using a minimally invasive technique to preserve facet joint stability and function without fusion reportedly improves the radicular symptoms in approximately 80% of patients and is considered one of the good surgical treatment choices for lumbar foraminal or extraforaminal stenosis. However, proper decompression was not possible because of the inability to access the foramen at the L5-S1 level due to prominence of the iliac crest. To overcome this challenge, endoscopy-based minimally invasive spine surgery has recently gained attention...
December 2018: Clinics in Orthopedic Surgery
Alfredo Tarantino, Justyna Paulina Jablonska, Paola D'Aprile
Objectives: The aim of this study was to determine the prevalence of "rheumatic" and "non-rheumatic" changes of the sacro-iliac joints (SIJ). Material and methods: We performed MRI in 210 patients with suspected inflammatory low back pain. We sorted and analysed the characteristics of sacroiliac bone lesions in "rheumatic" and "non-rheumatic" patients and assessed the diagnostic values of their extent and location. SIJ lesions were classified on the basis of their location into two categories: unilateral and bilateral...
2018: Reumatologia
Tuan-Mao Guo, Jian Lu, Yan-Li Xing, Guo-Xiong Liu, Hai-Yun Zhu, Lan Yang, Xi-Min Qiao
BACKGROUND: Transforaminal lumbar interbody fusion (TLIF) is an effective treatment of upper lumbar intervertebral disc herniation. However, its clinical efficacy for adjacent segment disc degeneration (ASDD) remains undefined. Therefore, the biomechanical evaluation of ASDD caused by TLIF after pedicle screw fixation (PSF) was explored via a three-dimensional (3D) finite element analysis. METHODS: Computed tomography (CT) images of a healthy male adult volunteer were used in this study...
November 29, 2018: World Neurosurgery
Abdulhamit Misir, Turan Bilge Kizkapan, Suleyman Kasim Tas, Kadir Ilker Yildiz, Mustafa Ozcamdalli, Mehmet Yetis
PURPOSE: This study aimed to compare differences in lumbosacral and spinopelvic parameters between pain developers and non-pain developers as well as the effects of various posture changes. METHODS: A total of 38 consecutive participants, 20 standing-induced low back pain developers (mean age: 27.7 ± 5.3; mean BMI: 22.64 ± 2.95) and 18 non-pain developers (mean age: 29.0 ± 7.5; mean BMI: 24.2 ± 1.87) (p > 0.05), were prospectively evaluated...
November 29, 2018: European Spine Journal
Ferran Jardí, Nari Kim, Michaël R Laurent, Rougin Khalil, Ludo Deboel, Dieter Schollaert, Harry van Lenthe, Brigitte Decallonne, Geert Carmeliet, Frank Claessens, Dirk Vanderschueren
Androgens via the androgen receptor (AR) are required for optimal male bone health. The target cell(s) for the effects of androgens on cortical bone remain(s) incompletely understood. In females, estrogen receptor alpha in neurons is a negative regulator of cortical and trabecular bone. Whether neuronal AR regulates bone mass in males remains unexplored. Here, we inactivated AR in neurons using a tamoxifen-inducible CreERT2 under the control of the neuronal promoter Thy1. Tamoxifen induced a 70-80% reduction of AR mRNA levels in Thy1-CreERT2 positive brain regions cerebral cortex and brainstem as well as in the peripheral nervous tissue of male neuronal AR knockout (N-ARKO) mice...
November 29, 2018: Journal of Bone and Mineral Research: the Official Journal of the American Society for Bone and Mineral Research
Ramsis F Ghaly, Tatiana Tverdohleb, Kenneth D Candido, Nebojsa Nick Knezevic
Background: Ependymomas represent 50-60% of all brain and central nervous system tumors. Previous lumbar spine surgery for resection of an ependymoma should not be considered a relative contraindication for the administration of epidural/subarachnoid anesthesia to patients in labor. Case Description: A 34-year-old G1P0, who underwent resection of an L1-L3 intramedullary ependymoma 8 years previously, presented in active labor with residual left leg numbness and tingling...
2018: Surgical Neurology International
Menekse Salar Barim, Richard F Sesek, M Fehmi Capanoglu, Phil Drinkaus, Mark C Schall, Sean Gallagher, Gerard A Davis
The impact of manual material handling such as lifting, lowering, pushing, pulling and awkward postures have been studied, and models using these external demands to assess risk of injury have been developed and employed by safety and health professionals. However, ergonomic models incorporating personal characteristics into a comprehensive model are lacking. This study explores the utility of adding personal characteristics such as the estimated L5/S1 Intervertebral Disc (IVD) cross-sectional area, age, gender and Body Mass Index to the Revised NIOSH Lifting Equation (RNLE) with the goal to improve risk assessment...
January 2019: Applied Ergonomics
Jacob J Banks, Graham E Caldwell
Tables of maximal acceptable weight limits (MAWL) are used to select safe lifting loads and help reduce workplace injuries. However, their subjective basis provides little information on the underlying load selection rationale, and few studies have examined MAWLs in relation to full-body joint demands. Therefore, link-segment biomechanical modeling was applied for 18 participants during three sagittal 4.3 lifts/minute tasks at chosen MAWL levels. Each lift produced unique kinematics, kinetics, MAWL loads and most highly stressed joints...
January 2019: Applied Ergonomics
(no author information available yet)
OBJECTIVEThe authors sought to investigate the efficiency of percutaneous endoscopic discectomy (PED) in adolescent patients with lumbar disc herniation (LDH), compare PED outcomes in adolescent patients with those in young adult LDH patients as controls, and discuss relevant technical notes.METHODSThis was a retrospective study involving 19 adolescent LDH patients (age > 13 and < 18 years, 20 discectomies) and 38 young adults (age < 40 years, 38 discectomies) who also had LDH and were matched to the adolescent group for sex and body mass index...
October 1, 2018: Journal of Neurosurgery. Pediatrics
(no author information available yet)
OBJECTIVEThe surgical correction of adult spinal deformity (ASD) often involves modifying lumbar lordosis (LL) to restore ideal sagittal alignment. However, corrections that include large changes in LL increase the risk for development of proximal junctional kyphosis (PJK). Little is known about the impact of cranial versus caudal correction in the lumbar spine on the occurrence of PJK. The goal of this study was to investigate the impact of the location of the correction on acute PJK development.METHODSThis study was a retrospective review of a prospective multicenter database...
October 1, 2018: Journal of Neurosurgery. Spine
Yosuke Yamaguchi, Kentaro Oh-Hashi, Yutaka Matsuoka, Hitomi Takemura, Shunsuke Yamakita, Megumi Matsuda, Teiji Sawa, Fumimasa Amaya
Little is known about the functional relationship between endoplasmic reticulum (ER) stress and development of pain hypersensitivity after nerve injury. The aim of this study was to investigate the role of ER stress in the development of pain hypersensitivity in the dorsal root ganglion (DRG) after spinal nerve ligation (SNL). SNL was performed in male Sprague-Dawley rats. Real-time PCR and immunohistochemistry were performed to investigate ER stress markers including glucose-regulated protein (GRP) 78, C/EBP homologous protein (CHOP), and spliced form of the X-box binding protein 1 (sXBP1) in L4 and L5 DRG...
December 1, 2018: Neuroscience
Felix Kiepe, Elvis Josef Hermann, Hans E Heissler, Helga Henseler, Peter M Vogt, Joachim K Krauss
We introduce a novel technique for the treatment of severe kyphosis in myelomeningocele. A 5-year-old paraplegic boy with myelomeningocele presented with severe thoracolumbar kyphosis and a chronic ulcus at the site of the gibbus. The myelomeningocele had been treated during his first week of life, and an accompanying Chiari type II malformation had been treated by ventriculoperitoneal shunting. He subsequently developed a rapidly progressive thoracolumbar kyphosis with an angle of 180° between T10 and L5...
November 27, 2018: Pediatric Neurosurgery
Jie Li, Wenkai Wang, Rui Zuo, Yue Zhou
BACKGROUND: Minimally invasive transformational lumbar interbody fusion (MI-TLIF) with unilateral pedicle screw (UPS) fixation was controversial. The aim of this study was to compare the stability between UPS and bilateral pedicle screw (BPS) fixation before and after graft fusion. METHODS: A L3-L5 finite element model was modified to simulate L4/5 MI-TLIF. Five different status of posterior instrumentation were simulated: UPS fixation or BPS fixation before and after graft fusion, and remove posterior instrumentation after graft fusion...
November 24, 2018: World Neurosurgery
Daniela Linhares, Pedro Cacho Rodrigues, Manuel Ribeiro da Silva, Rui Matos, Vitorino Veludo, Rui Pinto, Nuno Neves
PURPOSE: To describe and analyze the use of the V-rod technique described by Gillet to repair spondylolysis in both early and late postoperative periods. METHODS: Patients submitted to surgical correction of lumbar spondylolysis with a V-rod system were selected upon exclusion of adjacent disk degenerative changes and high-grade spondylolisthesis. A preoperative clinical (ODI and VAS) and radiological evaluation was performed, along with assessments on the early (clinical evaluation-up to 1 year) and late (clinical and radiological-at least 10 years) postoperative periods...
November 26, 2018: European Spine Journal
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