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https://www.readbyqxmd.com/read/30341712/thalidomide-and-neurotrophism
#1
REVIEW
Judith R Soper, S Fiona Bonar, Dudley J O'Sullivan, Janet McCredie, Hans-Georg Willert
BACKGROUND: Following the thalidomide disaster (1958-62), Henkel and Willert analysed the pattern of dysmelia in the long bones (J Bone Joint Surg Br. 51:399-414, 1969) and the extremities, Willert and Henkel (Z Orthop Ihre Grenzgeb. 107:663-75, 1970). Willert's material from deformed extremities is re-examined here asking "How does thalidomide reduce the skeleton?" MATERIALS AND METHODS: We reviewed the original data collection of Willert and Henkel (Z Orthop Ihre Grenzgeb...
October 19, 2018: Skeletal Radiology
https://www.readbyqxmd.com/read/30338477/automatic-lumbar-mri-detection-and-identification-based-on-deep-learning
#2
Yujing Zhou, Yuan Liu, Qian Chen, Guohua Gu, Xiubao Sui
The aim of this research is to automatically detect lumbar vertebras in MRI images with bounding boxes and their classes, which can assist clinicians with diagnoses based on large amounts of MRI slices. Vertebras are highly semblable in appearance, leading to a challenging automatic recognition. A novel detection algorithm is proposed in this paper based on deep learning. We apply a similarity function to train the convolutional network for lumbar spine detection. Instead of distinguishing vertebras using annotated lumbar images, our method compares similarities between vertebras using a beforehand lumbar image...
October 18, 2018: Journal of Digital Imaging: the Official Journal of the Society for Computer Applications in Radiology
https://www.readbyqxmd.com/read/30338337/epidural-needle-insertion-a-large-registry-analysis
#3
H Bomberg, N Paquet, A Huth, S Wagenpfeil, P Kessler, H Wulf, T Wiesmann, T Standl, A Gottschalk, J Döffert, W Hering, J Birnbaum, B Kutter, J Winckelmann, S Liebl-Biereige, W Meissner, O Vicent, T Koch, H Bürkle, D I Sessler, A Raddatz, T Volk
BACKGROUND: Dural puncture, paraesthesia and vascular puncture are the most common complications of epidural catheter insertion. Their association with variation in midline needle insertion depth is unknown. OBJECTIVE: This study evaluated the risk of dural and vascular punctures and the unwanted events paraesthesia and multiple skin punctures related to midline needle insertion depth. MATERIAL AND METHODS: A total of 14,503 epidural catheter insertions including lumbar (L1-L5; n = 5367), low thoracic (T7-T12, n = 8234) and upper thoracic (T1-T6, n = 902) insertions, were extracted from the German Network for Regional Anaesthesia registry between 2007 and 2015...
October 18, 2018: Der Anaesthesist
https://www.readbyqxmd.com/read/30338114/estimation-of-visceral-fat-in-9-to-13-year-old-girls-using-dual-energy-x-ray-absorptiometry-dxa-and-anthropometry
#4
V Lee, R Blew, M Hetherington-Rauth, D Blew, J-P Galons, T Hagio, J Bea, T Lohman, S Going
Objectives: Accumulation of visceral fat (VF) in children increases the risk of cardiovascular disease and type 2 diabetes, and measurement of VF in children using computed tomography and magnetic resonance imaging (MRI) is expensive. Dual-energy X-ray absorptiometry (DXA) may provide a low-cost alternative. This study aims to determine if DXA VF estimates can accurately estimate VF in young girls, determine if adding anthropometry would improve the estimate and determine if other DXA fat measures, with and without anthropometry, could be used to estimate VF in young girls...
October 2018: Obesity Science & Practice
https://www.readbyqxmd.com/read/30336901/vascular-and-lymphatic-complications-after-thoracic-duct-cannulation
#5
Jacob J Bundy, Ravi N Srinivasa, Rajiv N Srinivasa, Joseph J Gemmete, Anthony N Hage, Jeffrey Forris Beecham Chick
OBJECTIVE: The objective of this study was to determine the incidence of vascular and lymphatic complications after attempted transabdominal thoracic duct cannulation. METHODS: There were 58 patients who underwent attempted thoracic duct cannulation. Patients presented with chyle leak in the chest (n = 40), abdomen (n = 9), neck (n = 8), and pelvis (n = 1). Vertebral body level and geographic access, needle gauge, additional access for treatment, technical success, intervention performed, immediate and delayed complications, and follow-up duration were recorded...
November 2018: Journal of Vascular Surgery. Venous and Lymphatic Disorders
https://www.readbyqxmd.com/read/30333223/body-fatness-adipose-tissue-compartments-and-biomarkers-of-inflammation-and-angiogenesis-in-colorectal-cancer-the-colocare-study
#6
Caroline Himbert, Jennifer Ose, Johanna Nattenmüller, Christy A Warby, Andreana N Holowatyj, Jürgen Böhm, Tengda Lin, Mariam Haffa, Biljana Gigic, Sheetal Hardikar, Dominique Scherer, Lin Zielske, Petra Schrotz-King, Torsten Koelsch, Erin M Siegel, David Shibata, Alexis Ulrich, Martin Schneider, Stephen D Hursting, Hans-Ulrich Kauczor, Cornelia M Ulrich
BACKGROUND: Adiposity has been linked to both risk and prognosis of colorectal cancer; however, the impact of different fat areas [visceral (VFA) vs. subcutaneous fat area (SFA)] is unclear. We investigated associations between adiposity and biomarkers of inflammation and angiogenesis among patients with colorectal cancer. METHODS: Preoperative serum samples and computed tomography scans were obtained from 188 patients diagnosed with primary invasive stage I-IV colorectal cancer enrolled in the ColoCare Study...
October 17, 2018: Cancer Epidemiology, Biomarkers & Prevention
https://www.readbyqxmd.com/read/30327754/lumbar-intradiscal-invaginated-inferior-vena-cava-aneurysm
#7
Seung Young Jeong, Jin Uk Kim, Soo Yong Park, Jun Ho Lee, Kyu Jae Lee
The objective of this study is to present a rare case of an invaginated inferior vena cava (IVC) aneurysm in the lumbar intradiscal space. A 73-year-old woman with lower back pain and bilateral lower extremity swelling presented to the clinic. She had undergone spinal surgery performed thrice at the same site (L4-L5) in another hospital and a separate posterolateral fusion surgery procedure 3 years previously. On plain radiography, pseudarthrosis was observed at L4-L5 segment. Contrast computed tomography (CT) imaging revealed a dilatation of the IVC in the intradiscal space of L4-L5...
October 2018: NMC Case Report Journal
https://www.readbyqxmd.com/read/30327739/diagnostic-quandary-salmonella-agbeni-vertebral-osteomyelitis-and-epidural-abscess
#8
Ryan K Dahlberg, Mary Elizabeth Lyvers, Thomas K Dahlberg
Salmonella vertebral discitis/osteomyelitis is a rare manifestation of Salmonella infection. Here, we report a case of a 54-year-old Caucasian male who presented with five weeks of progressively worsening bilateral low back, buttock, and lower extremity pain following an 8-foot fall onto concrete from a ladder. Initial workup following the fall included hip X-ray and MRI of the lumbar spine and revealed only mild lumbar facet arthropathy and moderate left neural foraminal stenosis at L3-L4 without any concomitant hip or spine fracture...
2018: Case Reports in Orthopedics
https://www.readbyqxmd.com/read/30326694/the-relationship-of-facet-joint-orientation-and-tropism-with-lumbar-disc-herniation-and-degenerative-spondylolisthesis-in-the-lower-lumbar-spine
#9
Devanand Degulmadi, Bharat Dave, Ajay Krishnan, Denish Patel
Study Design: Retrospective study. Purpose: This study aimed to clarify the relationship of both facet tropism (FT) and the sagittally aligned facet (SAF) joint with lumbar disc herniation (LDH) and degenerative spondylolisthesis (DS). Overview of Literature: Despite several studies conducted, there is no consensus on the association of the SAF joint and FT with DH and DS. Methods: Between June 2015 and December 2017, magnetic resonance imaging scans of 250 consecutive patients who underwent surgery for LDH and DS were analyzed...
October 18, 2018: Asian Spine Journal
https://www.readbyqxmd.com/read/30326319/variation-in-human-vertebral-body-strength-for-vertebral-body-samples-from-different-locations-in-segments-l1-l5
#10
M B Ogurkowska, A Błaszczyk
BACKGROUND: The human spine, in particular the lumbar spine, is subject to significant compressive and bending stresses, which affect the structure of the bone tissue of the vertebrae. The more heterogeneous the structure of the spongy bone tissue, the less resistant the whole vertebral body. It is therefore necessary to establish variations in bone strength parameters within one particular vertebral body. METHODS: The research material comprised human L1-L5 lumbar vertebrae sampled from 15 donors aged 29-35...
October 10, 2018: Clinical Biomechanics
https://www.readbyqxmd.com/read/30326296/axons-morphometry-in-the-human-spinal-cord
#11
Tanguy Duval, Ariane Saliani, Harris Nami, Antonio Nanci, Nikola Stikov, Hugues Leblond, Julien Cohen-Adad
Due to the technical challenges of large-scale microscopy and analysis, to date only limited knowledge has been made available about axon morphometry (diameter, shape, myelin thickness, volume fraction), thereby limiting our understanding of neuronal microstructure and slowing down research on neurodegenerative pathologies. This study addresses this knowledge gap by establishing a state-of-the-art acquisition and analysis framework for mapping axon morphometry, and providing the first comprehensive mapping of axon morphometry in the human spinal cord...
October 13, 2018: NeuroImage
https://www.readbyqxmd.com/read/30325826/a-case-of-tophaceous-pseudogout-on-18f-fdg-pet-ct-imaging
#12
Guohua Shen, Minggang Su, Bin Liu, Anren Kuang
A 53-year-old man with a 10-year history of gout was admitted to our hospital due to chronic low back pain. Initial CT examinations showed a high-density mass with bone destruction of bilateral facet joints at the L3 to L5 level. MRI findings also revealed lesion with the dural sac compression. On PET/CT, the juxta-articular mass of bilateral L3 to L5 facet joints showed abnormal FDG uptake with an SUVmax of 4.2. The possible diagnosis may be gouty tophi; however, the biopsy revealed the diagnosis of calcium pyrophosphate dihydrate deposition disease, also referred to as pseudogout...
October 15, 2018: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/30323789/associations-between-lumbar-vertebral-bone-marrow-and-paraspinal-muscle-fat-compositions-an-investigation-by-chemical-shift-encoding-based-water-fat-mri
#13
Nico Sollmann, Michael Dieckmeyer, Sarah Schlaeger, Alexander Rohrmeier, Jan Syvaeri, Maximilian N Diefenbach, Dominik Weidlich, Stefan Ruschke, Elisabeth Klupp, Daniela Franz, Ernst J Rummeny, Claus Zimmer, Jan S Kirschke, Dimitrios C Karampinos, Thomas Baum
Purpose: Advanced magnetic resonance imaging (MRI) methods enable non-invasive quantification of body fat situated in different compartments. At the level of the lumbar spine, the paraspinal musculature is the compartment spatially and functionally closely related to the vertebral column, and both vertebral bone marrow fat (BMF) and paraspinal musculature fat contents have independently shown to be altered in various metabolic and degenerative diseases. However, despite their close relationships, potential correlations between fat compositions of these compartments remain largely unclear...
2018: Frontiers in Endocrinology
https://www.readbyqxmd.com/read/30322253/segmental-lordosis-of-the-spondylolytic-vertebrae-in-adolescent-lumbar-spondylolysis-differences-between-bilateral-l5-and-l4-spondylolysis
#14
Kazuhiro Sugawara, Noriyuki Iesato, Masaki Katayose
Study Design: Retrospective study. Purpose: This study aimed to investigate whether segmental lumbar hyperlordosis of the affected vertebra in patients with spondylolysis occurs only at L5 or also occurs at L4. Overview of Literature: To the best of our knowledge, increase in segmental lordosis of the spondylolytic vertebrae has only been investigated in bilateral L5 spondylolysis; it has not been examined at different levels of bilateral spondylolysis...
October 16, 2018: Asian Spine Journal
https://www.readbyqxmd.com/read/30322250/evaluation-of-the-degenerative-changes-of-the-distal-intervertebral-discs-after-internal-fixation-surgery-in-adolescent-idiopathic-scoliosis
#15
Morteza Dehnokhalaji, Mohammad Reza Golbakhsh, Babak Siavashi, Parham Talebian, Sina Javidmehr, Mohammadreza Bozorgmanesh
Study Design: Retrospective study. Purpose: Lumbar intervertebral disc degeneration is an important cause of low back pain. Overview of Literature: Spinal fusion is often reported to have a good course for adolescent idiopathic scoliosis (AIS). However, many studies have reported that adjacent segment degeneration is accelerated after lumbar spinal fusion. Radiography is a simple method used to evaluate the orientation of the vertebral column...
October 16, 2018: Asian Spine Journal
https://www.readbyqxmd.com/read/30321680/endoscope-assisted-anterior-lumbar-interbody-fusion-with-ct-guided-image-navigated-unilateral-cortical-bone-trajectory-screw-fixation-in-managing-adjacent-segment-disease-in-l5-s1-a-technical-note
#16
Vit Kotheeranurak, Guang-Xun Lin, Akaworn Mahatthanatrakul, Jin-Sung Kim
No abstract text is available yet for this article.
October 12, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/30320297/revisiting-radiographic-l5-s1-parallelism-using-mri-t1-mapping
#17
Julien Galley, Federico Balagué
Purpose: Thirty years ago, we reported that parallel aspect of the L5-S1 disc on a lateral view of the spine might be considered to be an initial stage of disk degeneration. The current study represents an attempt to increase the validity of parallel sign on conventional radiograph using MR real T1 mapping. Methods: Forty-four young asymptomatic volunteers (mean age 21.6 ± 2.3) underwent lumbar spine MRI, twice the same day, morning and afternoon. Dedicated sequences using the inversion-recovery technique were used to calculate the T1 relaxation time...
September 27, 2018: Journal of the Belgian Society of Radiology
https://www.readbyqxmd.com/read/30318428/age-related-changes-in-axial-and-sagittal-orientation-of-the-facet-joints-comparison-with-changes-in-degenerative-spondylolisthesis
#18
Masatoshi Morimoto, Kosaku Higashino, Hiroaki Manabe, Fumitake Tezuka, Kazuta Yamashita, Yoichiro Takata, Shoichiro Takao, Toshinori Sakai, Takashi Chikawa, Akihiro Nagamachi, Koichi Sairyo
BACKGROUND: Despite facet joints being three-dimensional structures, previous computed tomography and magnetic resonance imaging studies have evaluated facet joint orientation in only the axial plane. Facet joint orientation in the sagittal plane has rarely been studied using these imaging techniques. The aim of this study was to elucidate facet joint orientation in both the axial and sagittal planes on computed tomography. METHODS: A total of 568 patients (343 men, 225 women) (excluding orthopedic outpatients) for whom abdominal and pelvic computed tomography scans were obtained at our hospital between September 2010 and October 2012 were included...
October 11, 2018: Journal of Orthopaedic Science: Official Journal of the Japanese Orthopaedic Association
https://www.readbyqxmd.com/read/30315838/a-model-of-pain-behaviors-in-freely-moving-rats-generated-by-controllable-electrical-stimulation-of-the-peripheral-nerve
#19
Amber L Harris Bozer, Ai-Ling Li, Perry N Fuchs, Yuan B Peng
BACKGROUND: Neuropathic pain patients have described experiencing unprovoked, intermittent pain attacks with shooting, stabbing, and burning qualities. Rodent models used in previous literature usually only involve acute exposure, and/or are unable to manipulate the stimulation intensity in vivo by the experimenter during an experiment. NEW METHOD: This paper describes a method to induce controllable pain behaviors in rodents using a wireless portable electronic device that can be manipulated within the course of an experiment...
October 10, 2018: Journal of Neuroscience Methods
https://www.readbyqxmd.com/read/30314520/exploratory-analysis-of-predictors-of-revision-surgery-for-proximal-junctional-kyphosis-or-additional-postoperative-vertebral-fracture-following-adult-spinal-deformity-surgery-in-elderly-patients-a-retrospective-cohort-study
#20
Hiroshi Uei, Yasuaki Tokuhashi, Masafumi Maseda, Masahiro Nakahashi, Hirokatsu Sawada, Koji Matsumoto, Hiroyuki Miyakata
BACKGROUND: Proximal junctional kyphosis (PJK) following adult spinal deformity (ASD) surgery in elderly patients is markedly influenced by osteoporosis causing additional vertebral fracture and loosening of pedicle screws (PS). This study aimed to investigate the association between mean bone density represented in Hounsfield units (HU) on spinal computed tomography (CT) and revision surgery for PJK or postoperative additional vertebral fracture following ASD surgery in elderly patients...
October 12, 2018: Journal of Orthopaedic Surgery and Research
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