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https://www.readbyqxmd.com/read/30517765/antimicrobial-stewardship-programs-in-long-term-care-settings-a-meta-analysis-and-systematic-review
#1
Julie Hui-Chih Wu, Bradley J Langford, Nick Daneman, Jan O Friedrich, Gary Garber
BACKGROUND: Antimicrobial stewardship programs have been established in hospitals, but less studied in long-term care facilities (LTCFs), a setting with unique challenges related to patient populations and available resources. This systematic review sought to provide a comprehensive assessment of antimicrobial stewardship interventions implemented in LTCFs, using meta-analysis to examine their impact on overall antimicrobial use. METHODS: Electronic searches of MEDLINE, Embase, and CINAHL (1990 to July 2018) identified any antimicrobial stewardship interventions in LTCFs, with no restriction on patient population, study design, or outcomes...
December 5, 2018: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/30517412/management-of-elderly-people-with-stroke-strategies-based-on-action-research
#2
Luna Vitória Cajé Moura, Larissa Chaves Pedreira, Tânia Maria de Oliva Menezes, Nildete Pereira Gomes, Alyne Henri Motta Coifman, Alice de Andrade Santos
OBJECTIVE: To elaborate and implement, through an educational intervention with the nursing team of the Emergency Unit, strategies that contribute to the management of elderly people suspected/affected by Stroke. METHOD: Action research with eighteen nursing professionals working in the Emergency Unit of a reference hospital. The data were collected through five pedagogical workshops and systematized through the thematic analysis. RESULTS: After a situational analysis and identification of the difficulties in the management of these elderly, a synthesis chart was prepared with strategic actions, responsible professionals and perspectives for implementation in the short, medium and long term...
November 2018: Revista Brasileira de Enfermagem
https://www.readbyqxmd.com/read/30517396/educational-program-for-coronary-artery-disease-patients-results-after-one-year
#3
Eliana de Cássia Arantes, Carina Aparecida Marosti Dessotte, Rosana Aparecida Spadoti Dantas, Lidia Aparecida Rossi, Rejane Kiyomi Furuya
OBJECTIVE: To evaluate the long-term results of an educational program compared to usual care. METHOD: A longitudinal study in which 56 participants from a previous study (randomized controlled clinical trial) were evaluated twelve months after the percutaneous coronary intervention (PCI). Health-related quality of life (HRQoL) was assessed by the Medical Outcomes Study: 36-item Short Form (SF-36), and anxiety and depression symptoms were assessed by the Hospital Anxiety and Depression Scale (HADS)...
November 2018: Revista Brasileira de Enfermagem
https://www.readbyqxmd.com/read/30517265/red-wine-consumption-coronary-calcification-and-long-term-clinical-evolution
#4
P L da Luz, D Favarato, E H Moriguchi, W de Carli, N Bruscato, R I Mochiduky, P Schwartzman, C E Rochitte, F R Laurindo
Coronary artery calcification (CAC) is associated with atherosclerotic complications. However, elevated CAC may not always imply a worse prognosis. Herein, we report the clinical evolution of long-term red wine (RW) drinkers in relation to CAC. We followed 200 healthy male habitual RW drinkers and compared them to 154 abstainers for a period of 5.5 years. The initial evaluation included coronary computed tomography angiography (CTA), clinical, demographics, and laboratory data. CAC was quantified by the Agatston score...
November 29, 2018: Brazilian Journal of Medical and Biological Research, Revista Brasileira de Pesquisas Médicas e Biológicas
https://www.readbyqxmd.com/read/30517130/investigating-clinical-handover-and-healthcare-communication-for-outpatients-with-chronic-disease-in-india-a-mixed-methods-study
#5
Claire Humphries, Suganthi Jaganathan, Jeemon Panniyammakal, Sanjeev Singh, Shifalika Goenka, Prabhakaran Dorairaj, Paramjit Gill, Sheila Greenfield, Richard Lilford, Semira Manaseki-Holland
OBJECTIVES: Research concentrating on continuity of care for chronic, non-communicable disease (NCD) patients in resource-constrained settings is currently limited and focusses on inpatients. Outpatient care requires attention as this is where NCD patients often seek treatment and optimal handover of information is essential. We investigated handover, healthcare communication and barriers to continuity of care for chronic NCD outpatients in India. We also explored potential interventions for improving storage and exchange of healthcare information...
2018: PloS One
https://www.readbyqxmd.com/read/30516928/prognostic-significance-of-body-mass-index-in-patients-with-localized-renal-cell-carcinoma
#6
Chengtao Wang, Zebin Chen, Jun Dong, Bixiu Wen, Yong Fang
OBJECTIVE: To investigate the relationship between the pretreatment body mass index (BMI) and the clinical outcomes in patients with localized stage I - III renal cell carcinoma (RCC) surgically treated. MATERIALS AND METHODS: From January 2000 to December 2012, 798 patients with stage I - III RCC were recruited from First Affiliated Hospital and Cancer Center of Sun Yat - Sen University. Patients were divided into two groups of BMI < 25 kg / m2 or BMI ≥ 25 kg / m2 according to the World Health Organization classifications for Asian populations...
November 2018: International Braz J Urol: Official Journal of the Brazilian Society of Urology
https://www.readbyqxmd.com/read/30516798/association-of-hospital-surgical-aortic-valve-replacement-quality-with-30-day-and-1-year-mortality-after-transcatheter-aortic-valve-replacement
#7
Harun Kundi, Jeffrey J Popma, Kamal R Khabbaz, Louis M Chu, Jordan B Strom, Linda R Valsdottir, Changyu Shen, Robert W Yeh
Importance: Hospital outcomes for transcatheter aortic valve replacement (TAVR) may be dependent on the quality of evaluation, personnel, and procedural and postprocedural care common to patients undergoing cardiac surgery. Objectives: We sought to assess whether those hospitals with better patient outcomes for surgical aortic valve replacement (SAVR) subsequently achieved better TAVR outcomes after launching TAVR programs. Design, Setting, and Participants: This national cohort included US patients 65 years and older...
December 5, 2018: JAMA Cardiology
https://www.readbyqxmd.com/read/30515666/transsphenoidal-surgery-for-pituitary-adenomas-early-results-from-a-single-center
#8
I Karamouzis, M Caputo, C Mele, A Nuzzo, M Zavattaro, P Car, G Panzarasa, F Prodam, P Marzullo, Gianluca Aimaretti
OBJECTIVE: To evaluate early results of transsphenoidal surgery for pituitary adenomas. DESIGN: Retrospective evaluation of 90 consecutive patients undergoing endoscopic pituitary adenoma surgery (2007-2016) at "Maggiore della Carità" Hospital in Novara, Italy. Age at diagnosis, sex, symptoms at presentation, hormonal and radiological data, complications of surgery, and short-term follow-up information were collected. RESULTS: The majority of patients were male (M/F: 1...
December 4, 2018: Hormones: International Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/30515555/gestational-age-and-the-long-term-impact-on-children-s-infectious-urinary-morbidity
#9
Elisheva Padeh, Tamar Wainstock, Eyal Sheiner, Daniella Landau, Asnat Walfisch
PURPOSE: Given the negative impact of prematurity on offspring's health, we sought to determine whether different gestational ages at birth impact differently on the prevalence of childhood infectious urinary morbidity in the offspring. METHODS: In this population-based cohort analysis, all singleton deliveries occurring between 1991 and 2014 at a single regional tertiary medical center were included. Gestational age upon delivery was sub-divided into early preterm (< 34 weeks), late preterm (34-36 6/7 weeks), early term (37-38 6/7 weeks), full term (39-40 6/7 weeks), late term (41-41 6/7 weeks) and post-term (> 42 weeks)...
December 5, 2018: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/30515002/patient-survival-after-acute-voluntary-poisoning-with-a-huge-dose-of-oxcarbazepine-and-olanzapine
#10
Vasiliki Kalogera, Dimitrios Galopoulos, Gerasimos Eleftheriotis, Evangelia Meimeti, Ioannis Malios, Georgios Marathonitis, Chariclia Loupa
Introduction: Oxcarbazepine is a carbamazepine pre-drug with less drug interactions. Its adverse effects, including hyponatremia, somnolence and ataxia, are dose dependent. Olanzapine is an atypical antipsychotic drug most commonly used to manage psychoses and symptoms of irritability and aggressive behavior. Main side effects include extrapyramidal and anticholinergic symptoms, weight gain, and hyperglycemia. Case Report: In this manuscript a case of oxcarbazepine and olanzapine intoxication is discussed...
October 2018: Medical Archives
https://www.readbyqxmd.com/read/30514257/recurrence-of-allergic-bronchopulmonary-aspergillosis-after-adjunctive-surgery-for-aspergilloma-a-case-report-with-long-term-follow-up
#11
Kohei Horiuchi, Takanori Asakura, Naoki Hasegawa, Fumitake Saito
BACKGROUND: Coexistence of aspergilloma and allergic bronchopulmonary aspergillosis (ABPA) has rarely been reported. Although the treatment for ABPA includes administration of corticosteroids and antifungal agents, little is known about the treatment for coexisting aspergilloma and ABPA. Furthermore, the impact of surgical resection for aspergilloma on ABPA is not fully understood. Here, we present an interesting case of recurrent ABPA with long-term follow-up after surgical resection of aspergilloma...
December 4, 2018: BMC Pulmonary Medicine
https://www.readbyqxmd.com/read/30513820/clinical-course-serologic-response-and-long-term-outcome-in-elderly-patients-with-early-lyme-borreliosis
#12
Katarina Boršič, Rok Blagus, Tjaša Cerar, Franc Strle, Daša Stupica
Infected elderly people often present with signs and symptoms that differ from those in younger adults, but data on the association between patient age and presentation of early Lyme borreliosis (LB) are limited. In this study, the association between patient age (18⁻44 years, young vs. 45⁻64 years, middle-aged vs. ≥ 65 years, elderly) and disease course, microbiologic characteristics, and the long-term outcome of treatment was investigated prospectively in 1220 adult patients with early LB manifesting as erythema migrans (EM) at a single-center university hospital...
December 2, 2018: Journal of Clinical Medicine
https://www.readbyqxmd.com/read/30513488/smoking-during-pregnancy-as-a-possible-risk-factor-for-pediatric-neoplasms-in-the-offspring-a-population-based-cohort-study
#13
Roy Kessous, Tamar Wainstock, Eyal Sheiner
OBJECTIVE: The aim of this study was to evaluate the association between maternal smoking during pregnancy and future risk of childhood neoplasm risk. STUDY DESIGN: A population based cohort analysis comparing the risk for long-term childhood neoplasms in children born (1991-2014) to mothers that smoked during pregnancy vs. those that did not. Childhood neoplasms were pre-defined based on ICD-9 codes, as recorded in the hospital medical files. Children with congenital malformations and multiple gestations were excluded from the analysis...
November 27, 2018: Addictive Behaviors
https://www.readbyqxmd.com/read/30513431/rare-earth-element-fluxes-over-15-years-into-a-major-european-estuary-garonne-gironde-sw-france-hospital-effluents-as-a-source-of-increasing-gadolinium-anomalies
#14
Antoine Lerat-Hardy, Alexandra Coynel, Lionel Dutruch, Clément Pereto, Cécile Bossy, Teba Gil-Diaz, Marion-Justine Capdeville, Gérard Blanc, Jörg Schäfer
New and rapidly developing technologies imply the emission of emerging potentially toxic contaminants such as Rare Earth Elements (REEs). Yet, the lithology-derived quantities and anthropogenic contributions, especially from urban areas, to annual REE fluxes into fluvial-estuarine systems remain widely unknown. The Garonne River drains water from ~20% of the French land surface hosting about 5,200,000 inhabitants and two large cities. Based on long-term monitoring (2003-2017) of water discharges and dissolved REEs concentrations at the outlet of the Garonne Watershed upstream from Bordeaux, this study aims at assessing REE anomalies and evaluating temporal evolution of annual dissolved REE fluxes into the Gironde Estuary...
November 24, 2018: Science of the Total Environment
https://www.readbyqxmd.com/read/30511889/long-term-outcome-for-open-and-endoscopically-resected-sinonasal-tumors
#15
Jan Hagemann, Jana Roesner, Soenke Helling, Christian Jacobi, Johannes Doescher, Matthias Engelbarts, Julian Kuenzel, Philipp Krauss, Sven Becker, Christian Stephan Betz
OBJECTIVE: Endoscopic resection of sinonasal cancer has become an alternative to open craniofacial surgery and leads to safe and satisfying results in emerging numbers. Randomized study data comparing outcomes between approaches are missing. Hence, it remains unclear which subgroups of patients might profit most from each technique. We aimed to identify such patient and tumor characteristics and gather information for future prospective study design. STUDY DESIGN: Case series with chart review...
December 4, 2018: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/30511739/childhood-health-and-education-outcomes-following-early-term-induction-for-large-for-gestational-age-a-population-based-record-linkage-study
#16
Ibinabo Ibiebele, Jennifer R Bowen, Tanya A Nippita, Jonathan M Morris, Jane B Ford
INTRODUCTION: There is debate about optimal management of pregnancies with a large-for-gestational age baby. A recent randomized controlled trial reported that early term induction of labor reduced cesarean section rates and infant morbidity. However, long term childhood outcomes have not been assessed. The aim of this study was to assess maternal, neonatal and child health and education outcomes for large-for-gestational age babies induced at 37-38 weeks gestation. MATERIAL AND METHODS: Population-based record linkage study of term (37+ weeks), cephalic-presenting singleton pregnancies with a large-for-gestational age baby in New South Wales, Australia, 2002-2006...
December 4, 2018: Acta Obstetricia et Gynecologica Scandinavica
https://www.readbyqxmd.com/read/30511350/revisiting-the-concept-of-subjective-tolerability-to-antipsychotic-medications-in-schizophrenia-and-its-clinical-and-research-implications-30-years-later
#17
A George Awad
Schizophrenia is a long-term psychiatric disorder that impacts important mental functions and requires indefinite treatment, as well as psychosocial and economic support. The introduction of chlorpromazine, the first antipsychotic, and the subsequent development of a long list of similar dopamine-blocking antipsychotic medications, has changed the treatment of schizophrenia as medications have become the cornerstone of clinical management. The enthusiasm that greeted the introduction of antipsychotics was soon tempered by the realisation that they induced significant side effects, such as extrapyramidal and autonomic symptoms...
December 3, 2018: CNS Drugs
https://www.readbyqxmd.com/read/30511319/long-term-outcomes-of-video-assisted-thoracoscopic-surgery-lobectomy-vs-thoracotomy-lobectomy-for-stage-ia-non-small-cell-lung-cancer
#18
Risa Oda, Katsuhiro Okuda, Satoshi Osaga, Takuya Watanabe, Tadashi Sakane, Tsutomu Tatematsu, Keisuke Yokota, Hiroshi Haneda, Ryoichi Nakanishi
OBJECTIVES: Video-assisted thoracoscopic surgery (VATS) lobectomy is performed widely for patients with clinical stage I non-small cell lung cancer (NSCLC) because of its superior short-term outcomes to those of thoracotomy lobectomy. However, the long-term outcomes of VATS lobectomy vs. thoracotomy lobectomy remain controversial. METHODS: We reviewed the clinical data of 202 consecutive patients who underwent lobectomy for clinical stage IA NSCLC at our institution between January, 2008 and December, 2013...
December 3, 2018: Surgery Today
https://www.readbyqxmd.com/read/30511310/propensity-score-matched-comparison-of-short-term-and-long-term-outcomes-between-endoscopic-submucosal-dissection-and-surgery-for-treatment-of-early-gastric-cancer-in-a-western-setting
#19
R Bausys, A Bausys, J Stanaitis, I Vysniauskaite, K Maneikis, B Bausys, E Stratilatovas, K Strupas
BACKGROUND: Endoscopic submucosal dissection (ESD) is a standard treatment option for early gastric cancer (EGC) in Asia; however, data about ESD efficacy in Western populations are limited. Furthermore, outcomes of EGC treatment after ESD or surgery have not been compared in Western cohorts. This study aimed to compare short-term and long-term results of ESD and surgery for EGC. METHODS: This retrospective case-control study included patients with EGC treated in two largest cancer centers in Eastern Lithuania between 2005 and 2016...
December 3, 2018: Surgical Endoscopy
https://www.readbyqxmd.com/read/30511151/time-course-of-neoangiogenesis-after-indirect-bypass-surgery-for-moyamoya-disease-comparison-of-short-term-and-long-term-follow-up-angiography
#20
Yahui Zhao, Junlin Lu, Qian Zhang, Yan Zhang, Dong Zhang, Rong Wang, Yuanli Zhao
OBJECTIVE: Indirect bypass surgery, which induces spontaneous neoangiogenesis in ischemic brain tissue and improves cerebral blood flow, is an effective treatment for moyamoya disease (MMD). The time course of neoangiogenesis development has not yet been investigated. This study aimed to determine the critical period of neovascularization after indirect bypass in MMD patients. METHODS: Patients with MMD who underwent indirect bypass surgery at Peking University International Hospital between January 2015 and October 2017 were retrospectively reviewed...
December 3, 2018: Clinical Neuroradiology
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