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https://www.readbyqxmd.com/read/30497820/the-cambridge-experience-with-buried-bumpers
#1
Ayman Goneidy, Georgina Malakounides, Adil Aslam
AIM: Buried Bumper (BB) is a complication of percutaneous endoscopic gastrostomy (PEG) that leads to tube dysfunction and major morbidity. Although many techniques have been described to manage BB, none are universally adopted, and laparotomy remains the mainstay. We introduce a novel endoscopic technique in paediatric surgery that avoids laparotomy. METHODS: A retrospective review of medical records of patients who presented with BB to Cambridge University Hospital, UK, between January 2012 and June 2018 was done...
November 7, 2018: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/30482189/in-vitro-and-in-vivo-accumulation-of-magnetic-nanoporous-silica-nanoparticles-on-implant-materials-with-different-magnetic-properties
#2
Hilke Catherina Janßen, Dawid Peter Warwas, David Dahlhaus, Jessica Meißner, Piriya Taptimthong, Manfred Kietzmann, Peter Behrens, Janin Reifenrath, Nina Angrisani
BACKGROUND: In orthopedic surgery, implant-associated infections are still a major problem. For the improvement of the selective therapy in the infection area, magnetic nanoparticles as drug carriers are promising when used in combination with magnetizable implants and an externally applied magnetic field. These implants principally increase the strength of the magnetic field resulting in an enhanced accumulation of the drug loaded particles in the target area and therewith a reduction of the needed amount and the risk of undesirable side effects...
November 27, 2018: Journal of Nanobiotechnology
https://www.readbyqxmd.com/read/30481287/optima-a-phase-ii-dose-and-volume-de-escalation-trial-for-human-papillomavirus-positive-oropharyngeal-cancer
#3
T Y Seiwert, C C Foster, E A Blair, T G Karrison, N Agrawal, J M Melotek, L Portugal, R J Brisson, A Dekker, S Kochanny, Z Gooi, M W Lingen, V M Villaflor, D T Ginat, D J Haraf, E E Vokes
Background: Patients with HPV+ oropharyngeal squamous cell carcinoma (OPSCC) were assigned to dose and volume de-escalated radiotherapy (RT) or chemoradiotherapy (CRT) based on response to induction chemotherapy in an effort to limit treatment-related toxicity while preserving efficacy. Patients and Methods: Patients were classified as low-risk (≤T3, ≤N2B, ≤10 pack-year history [PYH]) or high-risk (T4 or ≥N2C or > 10 PYH). After 3 cycles of carboplatin/nab-paclitaxel, response was assessed using Response Evaluation Criteria in Solid Tumors 1...
November 27, 2018: Annals of Oncology: Official Journal of the European Society for Medical Oncology
https://www.readbyqxmd.com/read/30463774/comparing-outcomes-between-pull-versus-push-percutaneous-endoscopic-gastrostomy-in-acute-care-surgery-under-reported-pull-percutaneous-endoscopic-gastrostomy-incidence-of-tube-dislodgement
#4
Narong Kulvatunyou, Steven A Zimmerman, Moutamn Sadoun, Bellal A Joseph, Randall S Friese, Lynn M Gries, Terence O'Keeffe, Andrew L Tang
BACKGROUND: Percutaneous endoscopic gastrostomy (PEG) complications are often under-reported in the literature, especially regarding the incidence of tube dislodgement (TD). TD can cause significant morbidity depending on its timing. We compared outcomes between "push" and "pull" PEGs. We hypothesized that push PEGs, because of its T-fasteners and balloon tip, would have a lower incidence of TD and complications compared with pull PEGs. METHODS: We performed a chart review of our prospectively maintained acute care surgery database for patients who underwent PEG tube placement from July 1, 2009 through June 30, 2013...
December 2018: Journal of Surgical Research
https://www.readbyqxmd.com/read/30454430/endoscopically-assisted-transcervical-esophagogastric-tube-placement-for-nonoperative-intestinal-obstruction-an-alternative-to-peg-placement
#5
Asif Talukder, Karen Draper, Carsten Schroeder
No abstract text is available yet for this article.
April 1, 2018: American Surgeon
https://www.readbyqxmd.com/read/30424936/percutaneous-endoscopic-gastrostomy-indications-care-and-complications
#6
REVIEW
Carmen Molina Villalba, Juan Antonio Vázquez Rodríguez, Francisco Gallardo Sánchez
Percutaneous endoscopic gastrostomy (PEG) is an effective and safe method for nutritional support in patients with malnutrition and impossibility of oral intake with an estimated survival higher than the months that require enteral nutrition beyond four weeks. The main indications include neoplasms of the upper air-digestive tract and neurological diseases, with dementia currently considered a controversial indication. Anatomical alterations and infectious diseases are the most frequent contraindications. There are different endoscopic techniques; the most widely used being the "pull" method, with a low mortality...
November 10, 2018: Medicina Clínica
https://www.readbyqxmd.com/read/30416926/accurate-control-of-the-covalent-functionalization-of-single-walled-carbon-nanotubes-for-the-electro-enzymatically-controlled-oxidation-of-biomolecules
#7
Naoual Allali, Veronika Urbanova, Mathieu Etienne, Xavier Devaux, Martine Mallet, Brigitte Vigolo, Jean-Joseph Adjizian, Chris P Ewels, Sven Oberg, Alexander V Soldatov, Edward McRae, Yves Fort, Manuel Dossot, Victor Mamane
Single-walled carbon nanotubes (SWCNTs) were functionalized by ferrocene through ethyleneglycol chains of different lengths (FcETGn) and the functionalized SWCNTs (f-SWCNTs) were characterized by different complementary analytical techniques. In particular, high-resolution scanning electron transmission microscopy (HRSTEM) and electron energy loss spectroscopy (EELS) analyses support that the outer tubes of the carbon-nanotube bundles were covalently grafted with FcETGn groups. This result confirms that the electrocatalytic effect observed during the oxidation of the reduced form of nicotinamide adenine dinucleotide (NADH) co-factor by the f-SWCNTs is due to the presence of grafted ferrocene derivatives playing the role of a mediator...
2018: Beilstein Journal of Nanotechnology
https://www.readbyqxmd.com/read/30409477/primary-placement-of-a-skin-level-cecostomy-tube-for-antegrade-colonic-enema-administration-using-a-modification-of-the-laparoscopic-assisted-percutaneous-endoscopic-cecostomy-lapec
#8
Christopher D Graham, Leonel Rodriguez, Alejandro Flores, Samuel Nurko, Terry L Buchmiller
PURPOSE: Children failing medical management for severe constipation and/or fecal incontinence may undergo surgical intervention for antegrade enema administration. We present a modification of the laparoscopic-assisted percutaneous endoscopic cecostomy (LAPEC) procedure that allows primary placement of a skin-level device. METHODS: A single-institution retrospective review was performed from 2009 to 2015. In the modified technique the colonoscope is advanced to the cecum, cecal suspension sutures are placed under laparoscopic visualization, and percutaneous needle puncture of the cecum is performed under direct laparoscopic and endoscopic visualization...
October 2, 2018: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/30407112/laparoscopic-magnet-assisted-percutaneous-endoscopic-gastrostomy-placement
#9
Kara A Rothenberg, Barnard J Palmer, Olajire Idowu, Sunghoon Kim
BACKGROUND: There are various methods to place a gastrostomy tube. We report a laparoscopic method to place a standard percutaneous endoscopic gastrostomy (PEG) tube without the use of endoscopy. METHODS: Laparoscopic magnet-assisted PEG placement was carried out using an orogastric tube attached with a magnet that is used to retrieve the PEG wire that has been percutaneously placed into the stomach. RESULTS: Four pediatric patients (mean age 31 months) underwent a PEG tube placement using the laparoscopic magnet-assisted PEG tube insertion technique during 2017...
November 8, 2018: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/30401272/endoscopically-assisted-transcervical-esophagogastric-tube-placement-for-nonoperative-intestinal-obstruction-an-alternative-to-peg-placement
#10
Asif Talukder, Karen Draper, Carsten Schroeder
No abstract text is available yet for this article.
April 1, 2018: American Surgeon
https://www.readbyqxmd.com/read/30363413/percutaneous-endoscopic-transgastric-jejunostomy-peg-j-tube-placement-for-levodopa-carbidopa-intrajejunal-gel-therapy-in-the-interventional-radiology-suite-a-long-term-follow-up
#11
Maria Valeria Saddi, Marianna Sarchioto, Giulia Serra, Daniela Murgia, Valeria Ricchi, Marta Melis, Roberta Arca, Pierpaolo Carreras, Loredana Sitzia, Sandro Zedda, Giovanni Dui, Rosario Rossi, Anna Ticca, Maurizio Melis, Giovanni Cossu
Background: Percutaneous endoscopic gastrojejunostomy (PEG) and radiologically inserted gastrojejunostomy (RIG) are both safe and effective techniques for gastrojejunal tube placement. The authors compared these 2 procedures in patients with advanced Parkinson's disease (PD) who required the continuous intrajejunal delivery of a levodopa/carbidopa gel suspension (LCIG). Methods: Outcomes were retrospectively collated from 30 PEG and 12 RIG procedures performed at 2 centers in patients with advanced PD for the delivery of LCIG...
March 2018: Movement Disorders Clinical Practice
https://www.readbyqxmd.com/read/30337506/percutaneous-endoscopic-gastrostomy-peg-in-elderly-patients-with-dementia-and-anorexia-medical-and-ethical-issues-regarding-placement
#12
Luigi Sivero, Donato Alessandro Telesca, Maurizio Gentile, Giovanni Aprea, Guido Massa, Giovanni Cestaro, Michele Danzi, Stefania Sivero, Cesare Formisano
BACKGROUND AND AIMS: Ethical and medico-legal issues reviews of Percutaneous Endoscopic Gastrostomy (PEG) placement in elderly patients is an important topic of international medical literature. PEG is often inappropriately placed in patients with not spontaneous oral feeding intake, cause of unrealistic expectations. We performed a critical review of the literature for placement of PEG in geriatric patients. METHODS: A literature review was performed about the positioning of the PEG in geriatric patients with dementia and severe anorexia...
2018: Annali Italiani di Chirurgia
https://www.readbyqxmd.com/read/30320118/gastrostomy-tube-placement-by-radiological-methods-for-older-patients-requiring-enteral-nutrition-not-to-be-forgotten
#13
Vered Hermush, Yitshal Berner, Yael Katz, Yanina Kunin, Irena Krasniansky, Yael Schwartz, Debbie Mimran Nahon, Ana Elizariev, Gad Mendelson
Background: The use of gastrostomy tubes for long-term nutritional support in older patients is frequent. Percutaneous gastrostomy tube placement may be performed using various techniques, including endoscopic, surgical, and radiologically-guided methods. While percutaneous endoscopic gastrostomy (PEG) placement is the most widely used and accepted approach, experience with the use of percutaneous radiological gastrostomy (PRG) is more limited. Objective: To evaluate the safety and short-term outcomes of PRG in older patients requiring long-term enteral feeding...
2018: Frontiers in Medicine
https://www.readbyqxmd.com/read/30309731/magnetic-compression-anastomosis-magnamosis-in-a-porcine-esophagus-proof-of-concept-for-potential-application-in-esophageal-atresia
#14
Nicholas E Bruns, Ian C Glenn, Domenic R Craner, Steve J Schomisch, Michael R Harrison, Todd A Ponsky
BACKGROUND: Magnetic compression anastomosis (magnamosis) is the process of forming a sutureless anastomosis of the gastrointestinal tract using two magnetic Harrison rings. It has been shown to be effective in stomach, small bowel and colon, but has not been implemented in the esophagus. A pure esophageal atresia porcine model was developed to test the concept. METHODS: Five pigs weighing between 35 and 65 kg were used. In all pigs, a percutaneous endoscopic gastrostomy (PEG) tube was placed, and a right thoracotomy was performed...
September 29, 2018: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/30291404/comparison-of-major-complications-in-children-after-laparoscopy-assisted-gastrostomy-and-percutaneous-endoscopic-gastrostomy-placement-a-meta-analysis
#15
Filip Sandberg, Margrét Brands Viktorsdóttir, Martin Salö, Pernilla Stenström, Einar Arnbjörnsson
PURPOSE: A meta-analysis was performed to compare the rates of the major complications associated with two gastrostomy tube placement techniques in a pediatric population: laparoscopy-assisted gastrostomy (LAG) and percutaneous endoscopic gastrostomy (PEG). METHODS: The PubMed electronic database was queried for comparative studies of the two insertion techniques. The Newcastle-Ottawa scale (NOS) was used for the assessment of the quality and risk of bias in the included studies...
December 2018: Pediatric Surgery International
https://www.readbyqxmd.com/read/30285432/a-microbore-tubing-based-spiral-for-multistep-cell-fractionation
#16
Laura Pasitka, Danny van Noort, Wanyoung Lim, Sungsu Park, Carl-Fredrik Mandenius
Cells were separated with the aid of a multistep spiral fractionation device, utilizing hydrodynamic forces in a spiral tubing. The spiral was fabricated using "off-the-shelf" microbore tubing, allowing for cheap and fast prototyping to achieve optimal cell separation. As a first step, a model system with 20 and 40 μm beads was used to demonstrate the effectiveness of the multistep separation device. With an initial purity of 5%, a separation purity of 83% was achieved after a two-step separation with the addition of 0...
November 6, 2018: Analytical Chemistry
https://www.readbyqxmd.com/read/30281480/evaluation-of-skin-deformation-tactile-feedback-for-teleoperated-surgical-tasks
#17
Zhan Fan Quek, William Provancher, Allison Okamura
During interaction with objects using a tool, we experience force and tactile feedback. One form of tactile feedback is local fingerpad skin deformation. In this paper, we provide haptic feedback to users of a teleoperation system through a skin deformation tactile feedback device. The device is able to provide tangential and normal skin deformation in a coupled manner, and is designed so that users can grasp it with a precision grip using multiple fingerpads. By applying skin deformation feedback on multiple fingerpads, the device is able to provide multi-degree-of-freedom interaction force direction and magnitude information to the user...
October 1, 2018: IEEE Transactions on Haptics
https://www.readbyqxmd.com/read/30263877/refusal-of-peg-feeding-following-a-carotid-endarterectomy
#18
Adam L Jones
This case study presents a patient who has undergone right carotid endarterectomy complicated by glossopharyngeal nerve (or cranial nerve (CN) IX) injury. The patient had one transient ischaemic attack (TIA) three weeks before admission. A computed tomography (CT) scan two days after admission illustrated a right-sided parietal infarct. The patient subsequently had a CT angiogram, which showed a large, calcified plaque in the right internal carotid artery. He then underwent a right carotid endarterectomy...
July 25, 2018: Curēus
https://www.readbyqxmd.com/read/30248267/imatinib-loaded-micelles-of-hyaluronic-acid-derivatives-for-potential-treatment-of-neovascular-ocular-diseases
#19
Flavia Bongiovì, Calogero Fiorica, Fabio S Palumbo, Giulia Di Prima, Gaetano Giammona, Giovanna Pitarresi
In this work, new micellar systems able to cross corneal barrier and to improve the permeation of imatinib free base were prepared and characterized. HA-EDA-C16 , HA-EDA-C16 -PEG, and HA-EDA-C16 -CRN micelles were synthesized starting from hyaluronic acid (HA), ethylenediamine (EDA), hexadecyl chains (C16 ), polyethylene glycol (PEG), or l-carnitine (CRN). These nanocarriers showed optimal particle size and mucoadhesive properties. Imatinib-loaded micelles were able to interact with corneal barrier and to promote imatinib transcorneal permeation and penetration...
October 4, 2018: Molecular Pharmaceutics
https://www.readbyqxmd.com/read/30244635/bronchoscope-guided-percutaneous-endoscopic-gastrostomy-tube-placement-by-interventional-pulmonologists-a-feasibility-and-safety-study
#20
Erik Folch, Fayez Kheir, Amit Mahajan, Daniel Alape, Omar Ibrahim, Eugene Shostak, Adnan Majid
BACKGROUND: Percutaneous endoscopic gastrostomy (PEG) tube placement is a procedure frequently done in the intensive care unit. The use of a traditional endoscope can be difficult in cases of esophageal stenosis and theoretically confers an increased risk of infection due to its complex architecture. We describe a technique using the bronchoscope, which allows navigation through stenotic esophageal lesions and also minimizes the risk of endoscopy-associated infections. METHODS: Prospective series of patients who had PEG tube placement guided by a bronchoscope...
September 24, 2018: Journal of Intensive Care Medicine
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