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https://www.readbyqxmd.com/read/30309731/magnetic-compression-anastomosis-magnamosis-in-a-porcine-esophagus-proof-of-concept-for-potential-application-in-esophageal-atresia
#1
Nicholas E Bruns, Ian C Glenn, Domenic R Craner, Steve J Schomisch, Michael R Harrison, Todd A Ponsky
BACKGROUND: Magnetic compression anastomosis (magnamosis) is the process of forming a sutureless anastomosis of the gastrointestinal tract using two magnetic Harrison rings. It has been shown to be effective in stomach, small bowel and colon, but has not been implemented in the esophagus. A pure esophageal atresia porcine model was developed to test the concept. METHODS: Five pigs weighing between 35 and 65 kg were used. In all pigs, a percutaneous endoscopic gastrostomy (PEG) tube was placed, and a right thoracotomy was performed...
September 29, 2018: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/30291404/comparison-of-major-complications-in-children-after-laparoscopy-assisted-gastrostomy-and-percutaneous-endoscopic-gastrostomy-placement-a-meta-analysis
#2
Filip Sandberg, Margrét Brands Viktorsdóttir, Martin Salö, Pernilla Stenström, Einar Arnbjörnsson
PURPOSE: A meta-analysis was performed to compare the rates of the major complications associated with two gastrostomy tube placement techniques in a pediatric population: laparoscopy-assisted gastrostomy (LAG) and percutaneous endoscopic gastrostomy (PEG). METHODS: The PubMed electronic database was queried for comparative studies of the two insertion techniques. The Newcastle-Ottawa scale (NOS) was used for the assessment of the quality and risk of bias in the included studies...
October 5, 2018: Pediatric Surgery International
https://www.readbyqxmd.com/read/30285432/a-microbore-tubing-based-spiral-for-multi-step-cell-fractionation
#3
Laura Pasitka, Danny van Noort, Wanyoung Lim, Sungsu Park, Carl-Fredrik Mandenius
Cells were separated with the aid of a multi-step spiral fractionation device, utilising hydrodynamic forces in a spiral tubing. The spiral was fabricated using "off-the-shelf" microbore tubing, allowing for cheap and fast prototyping to achieve optimal cell separation. As a first step, a model system with 20 and 40 μm beads was used to demonstrate the effectiveness of the multi-step separation device. With an initial purity of 5%, a separation purity of 83% was achieved after a two-step separation with the addition of 0...
October 4, 2018: Analytical Chemistry
https://www.readbyqxmd.com/read/30281480/evaluation-of-skin-deformation-tactile-feedback-for-teleoperated-surgical-tasks
#4
Zhan Fan Quek, William Provancher, Allison Okamura
During interaction with objects using a tool, we experience force and tactile feedback. One form of tactile feedback is local fingerpad skin deformation. In this paper, we provide haptic feedback to users of a teleoperation system through a skin deformation tactile feedback device. The device is able to provide tangential and normal skin deformation in a coupled manner, and is designed so that users can grasp it with a precision grip using multiple fingerpads. By applying skin deformation feedback on multiple fingerpads, the device is able to provide multi-degree-of-freedom interaction force direction and magnitude information to the user...
October 1, 2018: IEEE Transactions on Haptics
https://www.readbyqxmd.com/read/30263877/refusal-of-peg-feeding-following-a-carotid-endarterectomy
#5
Adam L Jones
This case study presents a patient who has undergone right carotid endarterectomy complicated by glossopharyngeal nerve (or cranial nerve (CN) IX) injury. The patient had one transient ischaemic attack (TIA) three weeks before admission. A computed tomography (CT) scan two days after admission illustrated a right-sided parietal infarct. The patient subsequently had a CT angiogram, which showed a large, calcified plaque in the right internal carotid artery. He then underwent a right carotid endarterectomy...
July 25, 2018: Curēus
https://www.readbyqxmd.com/read/30248267/imatinib-loaded-micelles-of-hyaluronic-acid-derivatives-for-potential-treatment-of-neovascular-ocular-diseases
#6
Flavia Bongiovì, Calogero Fiorica, Fabio S Palumbo, Giulia Di Prima, Gaetano Giammona, Giovanna Pitarresi
In this work, new micellar systems able to cross corneal barrier and to improve the permeation of imatinib free base were prepared and characterized. HA-EDA-C16 , HA-EDA-C16 -PEG, and HA-EDA-C16 -CRN micelles were synthesized starting from hyaluronic acid (HA), ethylenediamine (EDA), hexadecyl chains (C16 ), polyethylene glycol (PEG), or l-carnitine (CRN). These nanocarriers showed optimal particle size and mucoadhesive properties. Imatinib-loaded micelles were able to interact with corneal barrier and to promote imatinib transcorneal permeation and penetration...
October 4, 2018: Molecular Pharmaceutics
https://www.readbyqxmd.com/read/30244635/bronchoscope-guided-percutaneous-endoscopic-gastrostomy-tube-placement-by-interventional-pulmonologists-a-feasibility-and-safety-study
#7
Erik Folch, Fayez Kheir, Amit Mahajan, Daniel Alape, Omar Ibrahim, Eugene Shostak, Adnan Majid
BACKGROUND: Percutaneous endoscopic gastrostomy (PEG) tube placement is a procedure frequently done in the intensive care unit. The use of a traditional endoscope can be difficult in cases of esophageal stenosis and theoretically confers an increased risk of infection due to its complex architecture. We describe a technique using the bronchoscope, which allows navigation through stenotic esophageal lesions and also minimizes the risk of endoscopy-associated infections. METHODS: Prospective series of patients who had PEG tube placement guided by a bronchoscope...
September 24, 2018: Journal of Intensive Care Medicine
https://www.readbyqxmd.com/read/30240081/use-of-nutritional-devices-in-cornelia-de-lange-syndrome-data-from-a-large-italian-cohort
#8
Valentina Decimi, Barbara Parma, Roberto Panceri, Chiara Fossati, Milena Mariani, Silvia Russo, Cristina C Gervasini, Maurizio Cheli, Anna Cereda, Angelo Selicorni
Cornelia de Lange syndrome (CdLS) is a genetic condition characterized by intellectual disability, peculiar facial dysmorphisms, multiorgan malformations, and growth problems. Majority cases of CdLS are caused by mutations in genes of Cohesin pathway. Although feeding problems are a well-known feature, no specific data have been published about the use of nutritional devices. We analyzed use, type, time of introduction, and duration of nutritional devices in 73 CdLS patients. In total, 29/73 (40%) used a device; nasogastric tube (NGT) in 28/73 (38%) and percutaneous endoscopic gastrostomy (PEG) in 7/73 (10%)...
September 2018: American Journal of Medical Genetics. Part A
https://www.readbyqxmd.com/read/30233750/a-ventriculoperitoneal-shunt-incidentally-found-in-the-stomach
#9
Dan Isaac Cohen-Addad, Kevin Hewitt, Donnie Bell
We report a case of a ventriculoperitoneal shunt incidentally found within the stomach while the patient was undergoing a percutaneous endoscopic gastrostomy (PEG) tube placement. Among the complications of ventriculoperitoneal shunt placement, bowel perforation is rare a complication found in 0.01%-0.07% of cases, and typically occurs in premature infants and neonates [1]. To date, less than 100 such cases have been recorded of which only a few have appeared in the radiological literature. Here we discuss the current literature, the radiological features, clinical presentations and the management...
December 2018: Radiology Case Reports
https://www.readbyqxmd.com/read/30197271/tolerability-and-safety-of-early-enteral-nutrition-in-children-after-percutaneous-endoscopic-gastrostomy-placement-a-multicentre-randomised-controlled-trial
#10
Anna Wiernicka, Małgorzata Matuszczyk, Agnieszka Szlagatys-Sidorkiewicz, Piotr Landowski, Ewa Toporowska-Kowalska, Beata Gębora-Kowalska, Katarzyna Popińska, Marta Sibilska, Urszula Grzybowska-Chlebowczyk, Sabina Więcek, Ewa Hapyn, Karolina Blimke-Kozieł, Jarosław Kierkuś
BACKGROUND & AIMS: We assessed the tolerability and safety of implementing early enteral nutrition in children at 3 h after percutaneous endoscopic gastrostomy (PEG) placement to establish an optimum feeding mode in paediatric patients that reduced the fasting period, the inadequate nutritional support interval, and the hospitalisation time. METHODS: Children with clinical indications for PEG placement were recruited from six medical centres in Poland to participate in the study...
August 28, 2018: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/30193459/surface-functionalized-polystyrene-latexes-using-itaconate-based-surfmers
#11
Saheli Chakraborty, S Ramakrishnan
Itaconic acid was readily transformed to a series of amphiphilic diesters via stepwise esterification of itaconic anhydride; the diesters carry one alkyl (cetyl or octyl) group and either a PEG, glyceryl, or dopamine segment. These diesters were used as surfmers for the preparation of polystyrene (PS) emulsions, with the expectation that the surface of the emulsion particles would carry PEG, glyceryl or dopamine units. NMR spectroscopic studies revealed that the surfmers were covalently incorporated into the polystyrene chains; furthermore, NMR tube polymerization experiments also confirmed that when the PEG surfmer was used, the PEG segments are indeed present on the surface of the emulsion particles...
October 2, 2018: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/30179861/feasibility-of-international-proposed-standardized-enteral-connector-for-semi-solid-formula-feeding
#12
Michio Maruyama, Shohei Iijima, Nobuya Ishibashi, Michio Inukai, Tetsuharu Oriishi, Naruo Kawasaki, Naomi Kurata, Yutaka Suzuki, Isao Tabei, Masahiro Chiba, Etsuko Nakamura, Takashi Higashiguchi
BACKGROUND/AIMS: The current study was undertaken to assess if the semi-solid formulas could be used with a new ENFit connector with similar force to current percutaneous endoscopic gastrostomy (PEG) tubes. METHODS: Experiment 1: We measured the applied pressure (force) needed to compress the syringe containing 7 viscous semi-solid formulas with a 20 Fr PEG tube and low-profile tube through the ENFit connector or the current connector. Experiment 2: This experiment was conducted to evaluate the compression force through 2 connectors in 3 infusion velocity, 7 PEG tube types with 2 semi-solid formulas...
2018: Annals of Nutrition & Metabolism
https://www.readbyqxmd.com/read/30132209/complications-of-percutaneous-endoscopic-and-radiologic-gastrostomy-tube-insertion-a-kasid-korean-association-for-the-study-of-intestinal-diseases-study
#13
Soo-Kyung Park, Ji Yeon Kim, Seong-Joon Koh, Yoo Jin Lee, Hyun Joo Jang, Soo Jung Park
BACKGROUND: Gastrostomy tube insertion is beneficial to selected patients, and percutaneous endoscopic gastrostomy (PEG) and percutaneous radiological gastrostomy (PRG) are two of the frequently used methods in gastrostomy. This study aimed to investigate the indications and complications of both PEG and PRG. METHODS: This was a retrospective multicenter cohort study. Patients who underwent initial PEG or PRG tube insertion for nutritional purpose between January 2010 and December 2015 at five university hospitals were included in the study...
August 21, 2018: Surgical Endoscopy
https://www.readbyqxmd.com/read/30042184/how-long-do-percutaneous-endoscopic-gastrostomy-feeding-tubes-last-a-retrospective-analysis
#14
Keith Siau, Tom Troth, Elizabeth Gibson, Anita Dhanda, Lauren Robinson, Neil C Fisher
BACKGROUND: Percutaneous endoscopic gastrostomy (PEG) tubes allow for long-term enteral feeding. Disk-retained PEG tubes may be suitable for long-term usage without planned replacement, but data on longevity are limited. We aimed to assess the rates and predictors of PEG longevity and post-PEG mortality. DESIGN: Single-centred retrospective cohort study of patients with disk-retained (Freka) PEG tubes. METHODS: All patients undergoing PEG between 2010 and 2013 were identified, and retrospective analysis of outcomes until 2017 (median 1062 days) was performed...
August 2018: Postgraduate Medical Journal
https://www.readbyqxmd.com/read/30037624/risk-of-gastric-cancer-following-percutaneous-endoscopic-gastrostomy-a-nationwide-population-based-cohort-study
#15
Chih-Cheng Tsao, Shih-Yu Lee, Wei-Kuo Chang, Kuen-Tze Lin, Sheng-Der Hsu, Chen-Liang Tsai, Chun-Shu Lin
OBJECTIVES: To investigate whether percutaneous endoscopic gastrostomy (PEG) tube placement is associated with increased risk of gastric cancer. METHODS: We conducted a nationwide population-based retrospective study in Taiwan. Inpatient data from 1997 to 2010 were collected from Taiwan National Health Insurance Research Database. Patients with age less than 20 years; those with histories of PEG before 2000; those with histories of cancers; and those diagnosed with gastric cancer before or within 6 months of the first PEG procedure were excluded...
September 2018: Medical Hypotheses
https://www.readbyqxmd.com/read/30014870/removal-of-percutaneous-endoscopic-gastrostomy-tubes-in-adults-using-the-cut-and-push-method-a-systematic-review
#16
J Pratt, S Green
BACKGROUND: PEG tubes are inserted for long term enteral feeding and may need to be removed at some point post insertion. A recognized method to remove the PEG is the cut and push method (CP). Some studies have suggested that CP is safe whilst others have reported complications and death. Subsequently the use of CP is not uniform but, if safe, could provide a cost effective, minimally invasive, alternative to gastroscopy. The aim of this study was to locate and critically appraise all publications relevant to CP in adult patients using a systematic approach...
October 2017: Clinical Nutrition ESPEN
https://www.readbyqxmd.com/read/30011232/buried-bumper-syndrome-do-we-have-enough-evidence
#17
Jose Bennell
Buried Bumper Syndrome (BBS) is a rare complication of percutaneous endoscopic gastrostomy (PEG) tubes. Advice in prevention guidelines differ, but locally agreed protocols can be agreed using the existing evidence. Consideration needs to be given as to how tightly a PEG is clipped after insertion to prevent gastric leakage, and how long after the procedure should it be loosened to prevent BBS. The distance a PEG tube is advanced and whether it should be rotated is also important in order to prevent BBS. The locally developed protocols need to include clear instructions for staff and patients and a supportive education programme, alongside clear record keeping...
July 1, 2018: British Journal of Community Nursing
https://www.readbyqxmd.com/read/30010147/tube-dependency-as-a-result-of-prematurity
#18
Karoline Pahsini, Sabine Marinschek, Zahra Khan, Berndt Urlesberger, Peter J Scheer, Marguerite Dunitz-Scheer
BACKGROUND: Enteral nutrition support (ENS) is a standard of care in all NICUs. As a result of long-term ENS, tube dependency can develop. Tube dependency is an inability to make the transition from tube to oral feeds despite the absence of medical reasons for ENS and might lead to symptoms like oral aversion and food refusal. This study aims to evaluate the prevalence of prematurity in a large cohort of tube dependent children. METHODS: Prospectively collected data on tube dependent children who participated in a program based on the "Graz Model of tube weaning" from January 2009 to December 2015 was analysed quantitatively...
2018: Journal of Neonatal-perinatal Medicine
https://www.readbyqxmd.com/read/30002806/repair-of-gastrocutaneous-fistula-utilizing-thickened-fluids-application-of-poiseuille-s-law-to-fistula-healing
#19
Simon P Batterham
Enterocutaneous fistulas are a rare occurrence after placement of a PEG tube. The key risk factor for their development is the time the PEG tube is in situ , giving time for the fistula tract to mature. Enterocutaneous fistulae are traditionally treated with parenteral nutrition or surgical management. We present a case of a 69-year-old woman who underwent surgical closure of an enterocutaneous fistula with a fibrin plug. The fistula recurred on post-operative Day 5, and the patient was placed on thickened fluids to increase the viscosity of the fluid exiting the fistula tract...
July 2018: Journal of Surgical Case Reports
https://www.readbyqxmd.com/read/29998988/-conservative-management-of-gastric-emphysema-and-hepatic-portal-venous-gas-a-case-report
#20
Masaya Iwamuro, Yuki Okamoto, Hiromitsu Kanzaki, Seiji Kawano, Shunsuke Tanabe, Hiromasa Yamamoto, Yoshiro Kawahara, Hiroyuki Okada
A 69-year-old Japanese man underwent successful percutaneous endoscopic gastrostomy (PEG) without any intra-procedural adverse event. However, 3 days postoperatively, he presented with melena and bloody discharge from the gastrostomy tube. Computed tomography revealed gastric emphysema, hepatic portal venous gas, portal vein thrombosis, and swelling of the ascending colon. We administered antibiotics and discontinued enteral feeding; this resulted in resolution of gastric emphysema, hepatic portal venous gas, and portal vein thrombosis and an improvement in the swelling of the ascending colon...
2018: Nihon Shokakibyo Gakkai Zasshi, the Japanese Journal of Gastro-enterology
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