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https://www.readbyqxmd.com/read/30113564/reducing-radiation-dose-for-high-resolution-flat-panel-ct-imaging-of-superior-semicircular-canal-dehiscence
#1
Amgad El Mekabaty, Seth E Pross, Mesha Martinez, John P Carey, Monica S Pearl
OBJECTIVE: High-resolution flat panel computed tomography (FPCT) is useful for the evaluation of temporal bone pathologies. While radiation exposure remains a concern, efforts have been devoted to reduce dose, while maintaining image quality. We hypothesize that removing the antiscatter grid (ASG) results in decreased radiation exposure, while maintaining diagnostic image quality for the evaluation of superior semicircular canal dehiscence (SSCD). METHODS: Ten patients with clinical suspicion for SSCD participated in this prospective study...
September 2018: Otology & Neurotology
https://www.readbyqxmd.com/read/30112436/antibody-drug-conjugates-in-bladder-cancer
#2
REVIEW
Panagiotis J Vlachostergios, Christopher D Jakubowski, Muhammad J Niaz, Aileen Lee, Charlene Thomas, Amy L Hackett, Priyanka Patel, Naureen Rashid, Scott T Tagawa
Urothelial carcinoma (UC) is characterized by expression of a plethora of cell surface antigens, thus offering opportunities for specific therapeutic targeting with use of antibody-drug conjugates (ADCs). ADCs are structured from two major constituents, a monoclonal antibody (mAb) against a specific target and a cytotoxic drug connected via a linker molecule. Several ADCs are developed against different UC surface markers, but the ones at most advanced stages of development include sacituzumab govitecan (IMMU-132), enfortumab vedotin (ASG-22CE/ASG-22ME), ASG-15ME for advanced UC, and oportuzumab monatox (VB4-845) for early UC...
July 30, 2018: Bladder Cancer
https://www.readbyqxmd.com/read/30105290/peroral-endoscopic-myotomy-is-effective-and-safe-in-non-achalasia-esophageal-motility-disorders-an-international-multicenter-study
#3
Mouen A Khashab, Pietro Familiari, Peter V Draganov, Hanaa Dakour Aridi, Joo Young Cho, Michael Ujiki, Ricardo Rio Tinto, Hubert Louis, Pankaj N Desai, Vic Velanovich, Eduardo Albéniz, Amyn Haji, Jeffrey Marks, Guido Costamagna, Jacques Devière, Yaseen Perbtani, Mason Hedberg, Fermin Estremera, Luis A Martin Del Campo, Dennis Yang, Majidah Bukhari, Olaya Brewer, Omid Sanaei, Lea Fayad, Amol Agarwal, Vivek Kumbhari, Yen-I Chen
Background and study aims : The efficacy of per oral endoscopic myotomy (POEM) in non-achalasia esophageal motility disorders such as esophagogastric junction outflow obstruction (EGJOO), diffuse esophageal spasm (DES), and jackhammer esophagus (JE) has not been well demonstrated. The aim of this international multicenter study was to assess clinical outcomes of POEM in patients with non-achalasia disorders, namely DES, JE, and EGJOO, in a large cohort of patients. Patients and methods : This was a retrospective study at 11 centers...
August 2018: Endoscopy International Open
https://www.readbyqxmd.com/read/30083337/detection-and-characterization-of-colorectal-polyps-using-high-definition-white-light-and-i-scan-evidence-based-consensus-recommendations-using-a-modified-delphi-process
#4
Pradeep Bhandari, Sreedhari Thayalasekaran, Ralf Keisslich, Raf Bisschops, Arthur Hoffmann, Rehan Haidry, Jose Esteban, Bartolomé López Viedma, Elina Godzhello, Majid Almadi, Helmut Neumann, Silvia Sanduleanu
Background: i-Scan is an image enhancement modality, which provides enhanced views of mucosal structures and vascular patterns. Methods: A modified Delphi process was used to develop a series of evidence-based statements on the role of high-definition white light (HDWL) and i-Scan for the detection and diagnosis of colorectal neoplasms. Each statement was voted to achieve consensus (i.e. >80% agreement). Results: Seven proposed statements achieved consensus: (1) HDWL is recommended rather than standard definition (SD) for detection and diagnosis of colorectal neoplasms; (2) HDWL colonoscopy with i-Scan improves polyp and adenoma detection rates when compared with SD colonoscopy; (3) HDWL + i-Scan is superior to HDWL alone for the optical diagnosis of colorectal neoplasms; (4) HDWL + i-Scan in expert hands meets American Society for Gastrointestinal Endoscopy (ASGE) in the Preservation and Incorporation of Valuable Endoscopic Innovations (PIVI) standards for optical diagnosis of diminutive neoplasms; (5) HDWL + i-Scan in non-expert hands does not meet ASGE PIVI standards for optical diagnosis of diminutive neoplasms; (6) optical diagnosis of polyps with i-Scan has a learning curve and needs systematic training; and (7) the performance of i-Scan for the in vivo diagnosis of colorectal neoplasms is similar to Narrow Band Imaging (NBI) and Fuji Intelligent Chromo Endoscopy (FICE)...
June 2018: United European Gastroenterology Journal
https://www.readbyqxmd.com/read/30078850/standards-of-care-for-procedural-sedation-focus-on-differing-perceptions-among-societies
#5
Satyen Parida, Pankaj Kundra, V K Mohan, Sandeep K Mishra
Adherence to established standards of care is important for anaesthesiologists to avoid undesirable legal consequences of their actions. The judiciary lays stress on the need to perpetuate healthy doctor-patient correspondence, good documentation, and to bestow a justifiable standard of care. But what defines standard of care and who delineates such standards is something that lacks clarity. The American Society for Gastrointestinal Endoscopy (ASGE) has recently released updated guidelines on the use of sedation and anaesthesia for gastrointestinal endoscopic procedures...
July 2018: Indian Journal of Anaesthesia
https://www.readbyqxmd.com/read/29989911/economic-outcomes-of-a-precision-medicine-blood-test-to-assess-obstructive-coronary-artery-disease-results-from-the-preset-registry
#6
Joseph A Ladapo, Matthew J Budoff, Pejman Azarmina, David Sharp, Alice Baker, Bruce Maniet, Lee Herman, Mark Monane
PURPOSE: The evaluation of obstructive coronary artery disease (CAD) is inefficient and costly. Previous studies of an age/sex/gene expression score (ASGES) in this diagnostic workup have shown a 96% negative predictive value, as well as an 85% decreased likelihood of cardiac referral among low-score outpatients at 45 days. The objective was to explore the one-year cost implications of ASGES use among symptomatic outpatients. DESIGN: A prospective PRESET Registry (NCT01677156) enrolled stable, nonacute adult patients presenting with symptoms suggestive of obstructive CAD at 21 U...
June 2018: Managed Care
https://www.readbyqxmd.com/read/29987568/the-asge-grading-system-for-ercp-can-predict-success-and-complication-rates-in-a-tertiary-referral-hospital
#7
Nadav Sahar, Danielle La Selva, Michael Gluck, S Ian Gan, Shayan Irani, Michael Larsen, Andrew S Ross, Richard A Kozarek
BACKGROUND: The utility of the American Society for Gastrointestinal Endoscopy (ASGE) grading scale assessing complexity of endoscopic retrograde cholangiopancreatography (ERCP) has not been evaluated in clinical practice. METHODS: Patients that underwent ERCP between January 2015 and December 2015 were included. Procedural difficulty was graded according to the grading system proposed by the ASGE workshop. Technical success rates and complications were recorded...
July 9, 2018: Surgical Endoscopy
https://www.readbyqxmd.com/read/29943988/granular-slow-release-fertilizer-from-urea-formaldehyde-ammonium-polyphosphate-and-amorphous-silica-gel-a-new-strategy-using-cold-extrusion
#8
Yang Xiang, Xudong Ru, Jinguo Shi, Jiang Song, Haidong Zhao, Yaqing Liu, Guizhe Zhao
A new granular, slow-release fertilizer prepared by a cold-extrusion strategy (GSRFEx) based on urea-formaldehyde (UF), ammonium polyphosphate (APP), and amorphous silica gel (ASG) was presented. Characterizations showed that there were strong hydrogen-bond interactions and good compatibility among UF, APP, and ASG in GSRFEx. The mechanical properties as well as the slow-release properties of GSRFEx were greatly enhanced after the addition of APP and ASG to UF. Rape pot experiments indicated that GSRFEx could improve N-use efficiency dramatically and thereby facilitate the growth of rape...
July 25, 2018: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/29905337/radiofrequency-ablation-devices
#9
Udayakumar Navaneethan, Nirav Thosani, Adam Goodman, Michael Manfredi, Rahul Pannala, Mansour A Parsi, Zachary L Smith, Shelby A Sullivan, Subhas Banerjee, John T Maple
No abstract text is available yet for this article.
October 2017: VideoGIE: an official video journal of the American Society for Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/29905301/egd-core-curriculum
#10
Richard S Kwon, Raquel E Davila, Daniel K Mullady, Mohammad A Al-Haddad, Ji Young Bang, Juliane Bingener-Casey, Brian P Bosworth, Jennifer A Christie, Gregory A Cote, Sarah Diamond, Jennifer Jorgensen, Thomas E Kowalski, Nisa Kubiliun, Joanna K Law, Keith L Obstein, Waqar A Qureshi, Francisco C Ramirez, Robert E Sedlack, Franklin Tsai, Shivakumar Vignesh, Mihir S Wagh, Daniel Zanchetti, Walter J Coyle, Jonathan Cohen
No abstract text is available yet for this article.
July 2017: VideoGIE: an official video journal of the American Society for Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/29791417/-accuracy-of-asge-predictors-in-diagnosis-of-coledocolithiasis-in-a-public-hospital-of-lima-peru
#11
Paúl Gomez Hinojosa, Jorge Espinoza-Ríos, Alvaro Bellido Caparo, José Luis Pinto Valdivia, Mavel Rosado Cipriano, Ricardo Prochazka Zarate, Eduar Bravo Alban, Arturo Zegarra Chang
BACKGROUND: The predictors proposed by the American Society of Gastrointestinal Endoscopy (ASGE) are commonly used topredict the presence and management of choledocholithiasis. OBJECTIVE: To evaluate the performance and precision of thepredictors of choledocholithiasis proposed by ASGE. MATERIALS AND METHODS: Prospective and longitudinal study performed ata third level hospital during January 2015 to June 2017. All patients with high and intermediate probability of choledocholithiasiswho underwent endoscopic retrograde cholangiopancreatography (ERCP) were included according to the criteria proposedby the ASGE...
January 2018: Revista de Gastroenterología del Perú: órgano Oficial de la Sociedad de Gastroenterología del Perú
https://www.readbyqxmd.com/read/29730228/an-international-multicenter-comparative-trial-of-eus-guided-gastrogastrostomy-assisted-ercp-versus-enteroscopy-assisted-ercp-in-patients-with-roux-en-y-gastric-bypass-anatomy
#12
Majidah Bukhari, Thomas Kowalski, Jose Nieto, Rastislav Kunda, Nitin K Ahuja, Shayan Irani, Apeksha Shah, David Loren, Olaya Brewer, Omid Sanaei, Yen-I Chen, Saowanee Ngamruengphong, Vivek Kumbhari, Vikesh Singh, Hanaa Dakour Aridi, Mouen A Khashab
BACKGROUND AND AIMS: ERCP is challenging in patients with Roux-en-Y gastric bypass (RYGB) anatomy. EUS-guided gastrogastrostomy (GG) creation is a promising novel technique to access the excluded stomach to facilitate conventional ERCP. We aimed to compare procedural outcomes and adverse events (AEs) between EUS-guided GG-assisted ERCP (EUS-GG-ERCP) and enteroscopy-assisted ERCP (e-ERCP) in patients with RYGB. METHODS: Patients with RYGB anatomy who underwent EUS-GG-ERCP or e-ERCP between 2014 and 2016 at 5 tertiary centers were included...
May 3, 2018: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/29704965/changes-in-problematic-anger-shame-and-disgust-in-anxious-and-depressed-adults-undergoing-treatment-for-emotion-dysregulation
#13
Andrada D Neacsiu, Joscelyn Rompogren, Jeremy W Eberle, Kibby McMahon
Emotion dysregulation, the pervasive difficulty managing negative emotions, is a core problem across mood and anxiety disorders. Anger, shame, and disgust are particularly problematic emotions, impacting both disorder severity and treatment outcome. We previously found that a 16-week dialectical behavior therapy skills training group (DBT-ST) was superior to an activities-based support group (ASG) in decreasing emotion dysregulation in 44 adults with high emotion dysregulation who met diagnostic criteria for an anxiety or depressive disorder...
May 2018: Behavior Therapy
https://www.readbyqxmd.com/read/29674323/hemoglobin-a-1c-accurately-predicts-continuous-glucose-monitoring-derived-average-glucose-in-youth-and-young-adults-with-cystic-fibrosis
#14
Christine L Chan, Emma Hope, Jessica Thurston, Timothy Vigers, Laura Pyle, Philip S Zeitler, Kristen J Nadeau
OBJECTIVE: In cystic fibrosis (CF), hemoglobin A1c (HbA1c ) is thought to underestimate glycemia. However, few studies have directly assessed the relationship between HbA1c and average glucose in CF. We determined the relationships among glycemic markers-HbA1c , fructosamine (FA), glycated albumin (%GA), and 1,5-anhydroglucitol (1,5-AG)-and continuous glucose monitoring (CGM) in CF, hypothesizing that alternate markers would better predict average sensor glucose (ASG) than HbA1c . RESEARCH DESIGN AND METHODS: CF participants and a group of healthy control subjects (HCs), ages 6-25 years, wore CGM for up to 7 days...
July 2018: Diabetes Care
https://www.readbyqxmd.com/read/29593696/transmission-of-turnip-yellows-virus-by-myzus-persicae-is-reduced-by-feeding-aphids-on-double-stranded-rna-targeting-the-ephrin-receptor-protein
#15
Michaël Mulot, Baptiste Monsion, Sylvaine Boissinot, Maryam Rastegar, Sophie Meyer, Nicole Bochet, Véronique Brault
Aphid-transmitted plant viruses are a threat for major crops causing massive economic loss worldwide. Members in the Luteoviridae family are transmitted by aphids in a circulative and non-replicative mode. Virions are acquired by aphids when ingesting sap from infected plants and are transported through the gut and the accessory salivary gland (ASG) cells by a transcytosis mechanism relying on virus-specific receptors largely unknown. Once released into the salivary canal, virions are inoculated to plants, together with saliva, during a subsequent feeding...
2018: Frontiers in Microbiology
https://www.readbyqxmd.com/read/29576004/volumetric-nephrogram-represents-renal-function-and-complements-aortic-anatomic-severity-grade-in-predicting-evar-outcomes
#16
Mark D Balceniuk, Lauren Trakimas, Claudia Aghaie, Doran Mix, Khurram Rasheed, Matthew Seaman, Jennifer Ellis, Roan Glocker, Adam Doyle, Michael C Stoner
INTRODUCTION: Chronic kidney disease (CKD) is a predictor of poor outcomes for patients undergoing endovascular aortic aneurysm repair (EVAR). Anatomic severity grade (ASG) represents a quantitative mechanism for assessing anatomical suitability for endovascular aortic repair. Anatomic severity grade has been correlated with repair outcomes and resource utilization. The purpose of this study was to identify a novel renal perfusion metric as a way to assist ASG with predicting EVAR outcomes...
July 2018: Vascular and Endovascular Surgery
https://www.readbyqxmd.com/read/29573782/asge-guideline-for-infection-control-during-gi-endoscopy
#17
Audrey H Calderwood, Lukejohn W Day, V Raman Muthusamy, James Collins, Ralph David Hambrick, Andrew S Brock, Nalini M Guda, Jonathan M Buscaglia, Bret T Petersen, Navtej S Buttar, Lauren G Khanna, Vladimir M Kushnir, Aparna Repaka, Nicolas A Villa, Glenn M Eisen
No abstract text is available yet for this article.
May 2018: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/29571779/the-asge-s-vision-for-developing-clinical-practice-guidelines-the-path-forward
#18
COMMENT
Sachin Wani, Shahnaz Sultan, Bashar Qumseya, Jennifer Michalek, John Dewitt, Steven A Edmundowicz, Karen L Woods
No abstract text is available yet for this article.
April 2018: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/29571175/development-and-validation-of-the-simple-endoscopic-classification-of-diminutive-and-small-colorectal-polyps
#19
Marietta Iacucci, Cristina Trovato, Marco Daperno, Oluseyi Akinola, David Greenwald, Seth A Gross, Arthur Hoffman, Jeffrey Lee, Brendan C Lethebe, Mark Lowerison, Jennifer Nayor, Helmut Neumann, Timo Rath, Silvia Sanduleanu, Prateek Sharma, Ralf Kiesslich, Subrata Ghosh, John R Saltzman
BACKGROUND: Prediction of histology of small polyps facilitates colonoscopic treatment. The aims of this study were: 1) to develop a simplified polyp classification, 2) to evaluate its performance in predicting polyp histology, and 3) to evaluate the reproducibility of the classification by trainees using multiplatform endoscopic systems. METHODS: In phase 1, a new simplified endoscopic classification for polyps - Simplified Identification Method for Polyp Labeling during Endoscopy (SIMPLE) - was created, using the new I-SCAN OE system (Pentax, Tokyo, Japan), by eight international experts...
August 2018: Endoscopy
https://www.readbyqxmd.com/read/29543510/subacromial-decompression-yields-a-better-clinical-outcome-than-therapy-alone-a-prospective-randomized-study-of-patients-with-a-minimum-10-year-follow-up
#20
Stefanos Farfaras, Ninni Sernert, Lars Rostgard Christensen, Erling K Hallström, Jüri-Toomas Kartus
BACKGROUND: The long-term outcome after the treatment of subacromial impingement syndrome (SAIS) with either nonsurgical or surgical methods has not been thoroughly investigated. Hypothesis/Purpose: The purpose was to evaluate the long-term clinical outcome and the presence of rotator cuff injuries and osteoarthritis (OA) after the surgical and nonsurgical treatment of SAIS. The hypothesis was that, at a minimum 10 years after the initial treatment, patients who had undergone acromioplasty would have a better clinical outcome and run a lower risk of developing rotator cuff ruptures and OA as compared with those treated with physical therapy...
May 2018: American Journal of Sports Medicine
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