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Irritable bowel syndrome, ibs, functional dyspepsia

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https://www.readbyqxmd.com/read/30114898/the-effect-of-trimebutine-on-the-overlap-syndrome-model-of-guinea-pigs
#1
Zahid Hussain, Da Hyun Jung, Young Ju Lee, Hyojin Park
Background/Aims: Functional dyspepsia (FD) and irritable bowel syndrome (IBS) are common gastrointestinal (GI) disorders and these patients frequently overlap. Trimebutine has been known to be effective in controlling FD co-existing diarrhea-dominant IBS, however its effect on overlap syndrome (OS) patients has not been reported. Therefore, we investigated the effect of trimebutine on the model of OS in guinea pigs. Methods: Male guinea pigs were used to evaluate the effects of trimebutine in corticotropin-releasing factor (CRF) induced OS model...
August 16, 2018: Journal of Neurogastroenterology and Motility
https://www.readbyqxmd.com/read/30101368/is-henoch-sch%C3%A3-nlein-purpura-a-susceptibility-factor-for-functional-gastrointestinal-disorders-in-children
#2
Rabia Miray Kisla Ekinci, Sibel Balcı, Okkes Ozgur Mart, Gokhan Tumgor, Sibel Yavuz, Halil Celik, Dilek Dogruel, Derya Ufuk Altintas, Mustafa Yilmaz
Henoch-Schönlein purpura (HSP), the most common childhood vasculitis is characterized by non-thrombocytopenic palpable purpura, arthritis/arthralgia, abdominal pain and renal involvement. Functional gastrointestinal disorders (FGIDs) are heterogeneous disease spectrum with unclear etiology and include the most common subtypes: functional dyspepsia, irritable bowel syndrome (IBS), functional abdominal pain and functional constipation. Formerly, FGIDs were known as non-organic disorders; however, recent advances revealed that low-grade inflammation may also play a role...
August 12, 2018: Rheumatology International
https://www.readbyqxmd.com/read/30094945/functional-gi-disorders-are-prevalent-among-pediatric-patients-with-persistent-asthma
#3
Ruben J Colman, Neal Bryan S Rosario, Analydia Gutierrez Bonilla, Gabriela Benavidez Alvarez, Joel Benavidez Alvarez, Vincent P Uy, Paulo R Pina, David H Rubin
AIM: Functional gastrointestinal disorders (such as functional abdominal pain, irritable bowel syndrome and functional dyspepsia) are a common cause of chronic GI symptoms in children. Prior studies demonstrated a high comorbidity of functional GI disorders (FGIDs) among patients with asthma. However, data exploring specific disease characteristics within the US populations are scarce. This study aimed to assess the prevalence and comorbidities of FGIDs among pediatric asthma patients at a university-affiliated urban community hospital...
August 9, 2018: Journal of Digestive Diseases
https://www.readbyqxmd.com/read/30094624/sleep-disturbances-are-commonly-reported-among-patients-presenting-to-a-gastroenterology-clinic
#4
Sarah Ballou, Eaman Alhassan, Elise Hon, Cara Lembo, Vikram Rangan, Prashant Singh, William Hirsch, Thomas Sommers, Johanna Iturrino, Judy Nee, Anthony Lembo
BACKGROUND: Poor sleep quality is common among patients with gastrointestinal (GI) disorders. However, few studies have assessed the presence of insomnia or reported circadian preferences and none have directly compared sleep between common GI conditions. AIMS: To compare clinical sleep characteristics in patients presenting to a tertiary care GI clinic for irritable bowel syndrome (IBS), functional dyspepsia (FD), inflammatory bowel disease (IBD), gastroesophageal reflux disease (GERD), and celiac disease (CD)...
August 9, 2018: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/30045261/an-observational-study-of-headaches-in-children-and-adolescents-with-functional-abdominal-pain-relationship-to-mucosal-inflammation-and-gastrointestinal-and-somatic-symptoms
#5
Craig Friesen, Meenal Singh, Vivekanand Singh, Jennifer V Schurman
Headaches and abdominal pain are among the most common pediatric pain conditions. Mast cells have been implicated in the pathophysiology of migraines, as well as functional dyspepsia (FD) and irritable bowel syndrome (IBS). The primary aims of the current study were to assess headache prevalence in patients with FD and to assess the association between headaches and mucosal mast cells and eosinophils. An additional aim was to explore associations of headache with other symptoms.We conducted a cross-sectional retrospective chart review of 235 consecutive patients with chronic abdominal pain...
July 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/30024695/frequency-of-food-hypersensitivity-in-patients-with-functional-gastrointestinal-disorders
#6
F W Ismail, S Abid, S Awan, F Lubna
BACKGROUND AND STUDY AIMS: Food hypersensitivity (FH), irritable bowel syndrome (IBS) and functional dyspepsia (FD) have many overlapping symptoms, including abdominal discomfort, bloating, and altered bowel habits. We aimed to determine the frequency of FH in patients with IBS and functional FD. PATIENTS AND METHODS: Adult patients of either gender diagnosed with IBS and/or FD as per the Rome III criteria were recruited. Patients underwent serological testing against 6 food allergens: beef, shrimp, egg white, milk, peanut, and soy-bean...
April 2018: Acta Gastro-enterologica Belgica
https://www.readbyqxmd.com/read/29956418/the-biology-first-hypothesis-functional-disorders-may-begin-and-end-with-biology-a-scoping-review
#7
P Enck, N Mazurak
While it is generally accepted that gastrointestinal infections can cause functional disturbances in the upper and lower gastrointestinal tract-known as postinfectious irritable bowel syndrome (PI-IBS) and functional dyspepsia (PI-FD)-it has still not been widely recognized that such an infection can also initiate functional non-intestinal diseases, and that non-intestinal infections can provoke both intestinal and non-intestinal functional disturbances. We conducted a scoping review of the respective literature and-on the basis of these data-hypothesize that medically unexplained functional symptoms and syndromes following an infection may have a biological (genetic, endocrine, microbiological) origin, and that psychological and social factors, which may contribute to the disease "phenotype," are secondary to this biological cause...
June 28, 2018: Neurogastroenterology and Motility: the Official Journal of the European Gastrointestinal Motility Society
https://www.readbyqxmd.com/read/29915405/wheat-intolerance-and-chronic-gastrointestinal-symptoms-in-an-australian-population-based-study-association-between-wheat-sensitivity-celiac-disease-and-functional-gastrointestinal-disorders
#8
Michael D E Potter, Marjorie M Walker, Michael P Jones, Natasha A Koloski, Simon Keely, Nicholas J Talley
OBJECTIVES: Wheat avoidance in the absence of celiac disease (CD) is common but occurrence of concurrent functional gastrointestinal disorders (FGIDs) in this group is uncertain. The aims of this study were to determine the prevalence of self-reported wheat or gluten sensitivity and doctor diagnosed CD in an Australian population, define the associated gastrointestinal (GI) symptoms and FGIDs, and determine the relationship between self-reported wheat sensitivity, demographic and medical factors...
July 2018: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/29906324/electroacupuncture-treatments-for-gut-motility-disorders
#9
REVIEW
J D Z Chen, M Ni, J Yin
Functional gastrointestinal (GI) diseases are common and there are patients who are refractory to medical therapies as not all treatments work in all patients. Consequently, a large number of patients with functional GI diseases use complementary and alternative medicine, such as acupuncture or electroacupuncture (EA). In this issue, Zheng et al. reported interesting results of a multi-center placebo-controlled clinical study on the use of EA for treating refractory functional dyspepsia; another study reported a multi-center clinical trial on EA for chronic functional constipation; Liang et al...
July 2018: Neurogastroenterology and Motility: the Official Journal of the European Gastrointestinal Motility Society
https://www.readbyqxmd.com/read/29904158/association-between-ultra-processed-food-consumption-and-functional-gastrointestinal-disorders-results-from-the-french-nutrinet-sant%C3%A3-cohort
#10
Laure Schnabel, Camille Buscail, Jean-Marc Sabate, Michel Bouchoucha, Emmanuelle Kesse-Guyot, Benjamin Allès, Mathilde Touvier, Carlos A Monteiro, Serge Hercberg, Robert Benamouzig, Chantal Julia
OBJECTIVES: Ultra-processed foods (UPF) consumption has increased over the last decades and is raising concerns about potential adverse health effects. Our objective was to assess the association between UPF consumption and four functional gastrointestinal disorders (FGIDs): irritable bowel syndrome (IBS), functional constipation (FC), functional diarrhea (FDh), and functional dyspepsia (FDy), in a large sample of French adults. METHODS: We analyzed dietary data of 33,343 participants from the web-based NutriNet-Santé cohort, who completed at least three 24 h food records, prior to a Rome III self-administered questionnaire...
June 15, 2018: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/29774764/irritable-bowel-syndrome-and-functional-dyspepsia-what-can-epidemiology-tell-us-about-etiology
#11
Nicholas J Talley, Gerald Holtmann
No abstract text is available yet for this article.
July 2018: Expert Review of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/29728848/effectiveness-of-menthacarin-on-symptoms-of-irritable-bowel-syndrome
#12
Ahmed Madisch, Stephan Miehlke, Joachim Labenz, Berenike Stracke, Stephan Köhler
Irritable bowel syndrome (IBS) and functional dyspepsia (FD) are common functional gastrointestinal disorders with overlapping symptoms. Effectiveness and safety of Menthacarin (Menthacarin® is the active ingredient of the product Carmenthin® [Dr. Willmar Schwabe GmbH & Co. KG, Karlsruhe, Germany]) in FD treatment were already demonstrated. We assessed the effectiveness of Menthacarin in reducing concomitant IBS-associated symptoms in FD patients. A systematic search to identify eligible double-blind, randomized controlled trials (RCTs) investigating Menthacarin in FD patients and focusing on IBS-associated symptoms was performed...
May 4, 2018: Wiener Medizinische Wochenschrift
https://www.readbyqxmd.com/read/29702295/functional-dyspepsia-and-severity-of-psychologic-symptoms-associate-with-postprandial-symptoms-in-patients-with-irritable-bowel-syndrome
#13
Daniel Pohl, Lukas Van Oudenhove, Hans Törnblom, Boris Le Nevé, Jan Tack, Magnus Simrén
BACKGROUND & AIMS: Patients with irritable bowel syndrome (IBS) have an increased response of postprandial symptoms to a combined lactulose nutrient challenge test, compared with healthy volunteers. We investigated the associations among comorbid functional dyspepsia (FD), severity of psychologic symptoms, and breath test results in response to this test. METHODS: We performed a prospective study of 205 patients with IBS (Rome III criteria), 94 of whom also had FD (IBS-FD), and 83 healthy volunteers in Sweden from 2008 through 2015...
April 24, 2018: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29681874/alexithymia-in-gastroenterology-and-hepatology-a-systematic-review
#14
Danilo Carrozzino, Piero Porcelli
Background: Alexithymia is a multifaceted personality construct that represents a deficit in the cognitive processing of emotions and is currently understood to be related to a variety of medical and psychiatric conditions. The present review aims to investigate the relationship of alexithymia with gastrointestinal (GI) disorders as functional gastrointestinal disorders (FGID, as irritable bowel syndrome (IBS) and functional dyspepsia) and inflammatory bowel disease (IBD) [ulcerative colitis (UC) and Crohn's disease (CD)] and liver diseases as chronic hepatitis C (CHC), cirrhosis, and liver transplantation...
2018: Frontiers in Psychology
https://www.readbyqxmd.com/read/29605983/self-reported-sleep-impairment-in-functional-dyspepsia-and-irritable-bowel-syndrome
#15
Seung Young Kim, Rok Seon Choung, Seung Ku Lee, Jung Wan Choe, Sung Woo Jung, Jong Jin Hyun, Ja Seol Koo, Sang Woo Lee, Chol Shin
Background/Aims: Sleep impairment is a common complaint among patients with irritable bowel syndrome (IBS) and functional dyspepsia (FD). This study aimed to evaluate the prevalence of sleep impairment in FD or IBS patients, and to determine whether IBS-FD overlap induced more sleep disturbance than FD or IBS alone. Methods: A population-based cohort in South Korea including 2251 subjects was asked about gastrointestinal symptoms including IBS and dyspepsia-related symptoms...
April 30, 2018: Journal of Neurogastroenterology and Motility
https://www.readbyqxmd.com/read/29550809/presenting-symptoms-and-delay-in-diagnosis-of-gastrointestinal-and-pancreatic-neuroendocrine-tumours
#16
Ron Basuroy, Cathy Bouvier, John K Ramage, Maia Sissons, Alexandra Kent, Raj Srirajaskanthan
The gastrointestinal tract and pancreas are common primary sites for neuroendocrine tumours (NETs). Patients often report a long duration of non-specific symptoms in the year prior to diagnosis. The aims of this study were, firstly, to establish pre-diagnosis patterns of symptoms, and secondly, to determine the time from onset of symptoms to NET diagnosis and understand the interaction with primary and secondary healthcare providers. A survey was designed on a web-based survey platform with the focus on patient symptoms prior to diagnosis and a screen for functional diarrhoea (Rome III criteria [C4])...
2018: Neuroendocrinology
https://www.readbyqxmd.com/read/29549882/classification-of-pediatric-functional-gastrointestinal-disorders-related-to-abdominal-pain-using-rome-iii-vs-rome-iv-criterions
#17
Trent Edwards, Craig Friesen, Jennifer V Schurman
BACKGROUND: The primary purpose of this study was to compare Rome III and IV evaluation criteria for irritable bowel syndrome (IBS), functional dyspepsia (FD), and an overlap syndrome consisting of both IBS and FD by assessing the frequency of each diagnosis in a population of children with chronic abdominal pain. Frequencies of Rome IV FD subtypes of postprandial distress syndrome (PDS) and epigastric pain syndrome (EPS) were determined and FD/IBS overlap symptom associations were also assessed...
March 17, 2018: BMC Gastroenterology
https://www.readbyqxmd.com/read/29533398/identification-of-individuals-with-functional-dyspepsia-with-a-simple-minimally-invasive-test-a-single-center-cohort-study-of-the-oral-capsaicin-test
#18
Johann Hammer
OBJECTIVES: The diagnosis of functional dyspepsia (FD) is challenging due to the lack of reliable biological markers to support the diagnosis. We assessed the relevance of a previously validated simple test for chemical hypersensitivity in the setting of a gastrointestinal outpatient department. METHODS: A total of 224 outpatients who were referred for evaluation of gastrointestinal symptoms in the absence of alarm symptoms swallowed a capsule containing 0.75 mg capsaicin...
April 2018: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/29435308/complementary-and-alternative-treatment-in-functional-dyspepsia
#19
REVIEW
Giuseppe Chiarioni, Marcella Pesce, Alberto Fantin, Giovanni Sarnelli
Introduction and aim: The popularity of complementary and alternative medicine (CAM) in treating functional gastrointestinal disorders (FGIDs) has steadily increased in Western countries. We aimed at analyzing available data on CAM effectiveness in functional dyspepsia (FD) patients. Methods: A bibliographical search was performed in PubMed using the following keywords: "complementary/alternative medicine," "hypnosis," "acupuncture" and/or "functional dyspepsia...
February 2018: United European Gastroenterology Journal
https://www.readbyqxmd.com/read/29421817/stw-5-iberogast-therapy-in-gastrointestinal-functional-disorders
#20
REVIEW
Peter Malfertheiner
Functional gastrointestinal disorders (FGIDs) are very common and affect populations worldwide. A majority of patients are affected by a variety of heterogenous gastrointestinal symptoms (GIS) related to the upper and lower digestive system with frequent overlap and mostly of mild to moderate degree. The herbal medicinal preparation STW 5 is documented as an effective therapeutic option for treating FGID. Studies Conducted in Summary: STW 5 has been in use for more than 50 years in clinical practice and proven to be effective and safe in the management of FGID...
2017: Digestive Diseases
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