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Adam J Katz

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https://www.readbyqxmd.com/read/30496540/international-stakeholder-community-of-pain-experts-and-leaders-call-for-an-urgent-action-on-forced-opioid-tapering
#1
Beth D Darnall, David Juurlink, Robert D Kerns, Sean Mackey, Brent Van Dorsten, Keith Humphreys, Julio A Gonzalez-Sotomayor, Andrea Furlan, Adam J Gordon, Debra B Gordon, Diane E Hoffman, Joel Katz, Stefan G Kertesz, Sally Satel, Richard A Lawhern, Kate M Nicholson, Rosemary C Polomano, Owen D Williamson, Heath McAnally, Ming-Chih Kao, Stephan Schug, Robert Twillman, Terri A Lewis, Richard L Stieg, Kate Lorig, Theresa Mallick-Searle, Robert W West, Sarah Gray, Steven R Ariens, Jennifer Sharpe Potter, Penney Cowan, Chad D Kollas, Danial Laird, Barby Ingle, J Julian Grove, Marian Wilson, Kashelle Lockman, Fiona Hodson, Carol S Palackdharry, Roger B Fillingim, Jeffrey Fudin, Jennifer Barnhouse, Ajay Manhapra, Steven R Henson, Bruce Singer, Marie Ljosenvoor, Marlisa Griffith, Jason N Doctor, Kimeron Hardin, Cathleen London, Jon Mankowski, Andrea Anderson, Linda Ellsworth, Lisa Davis Budzinski, Becky Brandt, Greg Harkootley, Debbie Nickels Heck, Mark J Zobrosky, Celeste Cheek, Megan Wilson, Cynthia E Laux, Geralyn Datz, Justin Dunaway, Eileen Schonfeld, Melissa Cady, Thérèse LeDantec-Boswell, Meredith Craigie, John Sturgeon, Pamela Flood, Melita Giummarra, Jessica Whelan, Beverly E Thorn, Richard L Martin, Michael E Schatman, Maurice D Gregory, Joshua Kirz, Patti Robinson, James G Marx, Jessica R Stewart, Phillip S Keck, Scott E Hadland, Jennifer L Murphy, Mark A Lumley, Kathleen S Brown, Michael S Leong, Mechele Fillman, James W Broatch, Aaron Perez, Kristine Watford, Kari Kruska, Dokyoung Sophia You, Stacy Ogbeide, Amy Kukucka, Susan Lawson, James B Ray, T Wade Martin, James B Lakehomer, Anne Burke, Robert I Cohen, Peter Grinspoon, Marc S Rubenstein, Stephani Sutherland, Kristie Walters, Travis Lovejoy
No abstract text is available yet for this article.
November 29, 2018: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/30398913/-please-help-me-see-the-dragon-i-am-slaying-implementation-of-a-novel-patient-pathologist-consultation-program-and-survey-of-patient-experience
#2
Adam L Booth, Matthew S Katz, Michael J Misialek, Timothy Craig Allen, Lija Joseph
CONTEXT.—: Pathologists evaluate human disease and teach medical students, residents, and clinicians. Historically recognized as the "doctor's doctor," pathologists are well suited to be a direct patient resource of individualized, accurate information. OBJECTIVE.—: To develop and implement a pathology consultation service whereby patients review their tissue slides directly with the pathologists. DESIGN.—: A pathologist conducted patient consultations, reviewing biopsy or surgery findings on a multiheaded microscope or computer screen...
November 6, 2018: Archives of Pathology & Laboratory Medicine
https://www.readbyqxmd.com/read/30383584/historical-roots-of-modern-plastic-surgery-a-cited-reference-analysis
#3
Mustafa Chopan, Lohrasb Sayadi, Patrick J Buchanan, Adam J Katz, Bruce A Mast
BACKGROUND: Highly cited publications are referred to as citation classics and can signify important contributions to a discipline. Although citation classics in plastic surgery have been identified, none were published before 1960. Citation classics in earlier periods may contain the historical roots or intellectual origins of the field. We set out to identify such scholarly works and analyze their characteristics. METHODS: A novel technique of citation analysis, referred to as reference publication year spectroscopy, was used to analyze the literature...
October 31, 2018: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/30245019/efficacy-of-breast-reconstruction-with-fat-grafting-a-systematic-review-and-meta-analysis
#4
REVIEW
Mikkel Herly, Mathias Ørholt, Andreas Larsen, Christian B Pipper, Rikke Bredgaard, Christina S Gramkow, Adam J Katz, Krzysztof T Drzewiecki, Peter V Vester-Glowinski
BACKGROUND: Breast reconstruction with fat grafting is a new alternative to prosthetic implants and flaps for women with breast cancer. In this study, we investigate the efficacy of fat grafting for breast reconstruction in a meta-analysis. METHODS: The study followed the PRISMA and MOOSE guidelines for systematic reviews and meta-analyses. Studies were included if the patients underwent complete breast reconstruction with fat grafting as the only treatment modality...
December 2018: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
https://www.readbyqxmd.com/read/30153023/hydrophobic-inorganic-oxide-pigments-via-polymethylhydrosiloxane-grafting-dispersion-in-aqueous-solution-at-extraordinarily-high-solids-concentrations
#5
Yijun Guo, Manish K Mishra, Futianyi Wang, Joseph Jankolovits, Ahmet Kusoglu, Adam Z Weber, Ant Van Dyk, Kebede Beshah, James C Bohling, John A Roper Iii, Clayton J Radke, Alexander Katz
Building on the recent demonstration of aqueous-dispersible hydrophobic pigments that retain their surface hydrophobicity even after drying, we demonstrate the synthesis of surface-modified Ti-Pure R-706 (denoted R706) titanium dioxide-based pigments, consisting of a thin (one to three monolayers) grafted polymethylhydrosiloxane (PMHS) coating, which (i) are hydrophobic in the dry state according to capillary rise and dynamic vapor sorption measurements and (ii) form stable aqueous dispersions at solid contents exceeding 75 wt % (43 vol %), without added dispersant, displaying similar rheology to R706 native oxide pigments at 70 wt % (37 vol %) consisting of an optimal amount of conventional polyanionic dispersant (0...
October 2, 2018: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/30152296/developing-a-real-time-pcr-assay-based-on-multiplex-high-resolution-melt-curve-analysis-a-pilot-study-in-detection-and-discrimination-of-soil-transmitted-helminth-and-schistosome-species
#6
Lucas J Cunningham, J Russell Stothard, Mike Osei-Atweneboana, Samuel Armoo, Jaco J Verweij, Emily R Adams
With the push towards control and elimination of soil-transmitted helminthiasis and schistosomiasis in low- and middle-income countries, there is a need to develop alternative diagnostic assays that complement the current in-country resources, preferably at a lower cost. Here, we describe a novel high-resolution melt (HRM) curve assay with six PCR primer pairs, designed to sub-regions of the nuclear ribosomal locus. Used within a single reaction and dye detection channel, they are able to discriminate Ancylostoma duodenale, Necator americanus, Strongyloides stercoralis, Ascaris lumbricoides, Trichuris trichiuria and Schistosoma spp...
November 2018: Parasitology
https://www.readbyqxmd.com/read/30053297/lewy-body-pathology-and-chronic-traumatic-encephalopathy-associated-with-contact-sports
#7
Jason W Adams, Victor E Alvarez, Jesse Mez, Bertrand R Huber, Yorghos Tripodis, Weiming Xia, Gaoyuan Meng, Caroline A Kubilus, Kerry Cormier, Patrick T Kiernan, Daniel H Daneshvar, Alicia S Chua, Sarah Svirsky, Raymond Nicks, Bobak Abdolmohammadi, Laney Evers, Todd M Solomon, Jonathan D Cherry, Nurgul Aytan, Ian Mahar, Sherral Devine, Sanford Auerbach, Michael L Alosco, Christopher J Nowinski, Neil W Kowall, Lee E Goldstein, Brigid Dwyer, Douglas I Katz, Robert C Cantu, Robert A Stern, Rhoda Au, Ann C McKee, Thor D Stein
Traumatic brain injury has been associated with increased risk of Parkinson disease and parkinsonism, and parkinsonism and Lewy body disease (LBD) can occur with chronic traumatic encephalopathy (CTE). To test whether contact sports and CTE are associated with LBD, we compared deceased contact sports athletes (n = 269) to cohorts from the community (n = 164) and the Boston University Alzheimer disease (AD) Center (n = 261). Participants with CTE and LBD were more likely to have β-amyloid deposition, dementia, and parkinsonism than CTE alone (p < 0...
September 1, 2018: Journal of Neuropathology and Experimental Neurology
https://www.readbyqxmd.com/read/29950434/neuropalliative-care-priorities-to-move-the-field-forward
#8
REVIEW
Claire J Creutzfeldt, Benzi Kluger, Adam G Kelly, Monica Lemmon, David Y Hwang, Nicholas B Galifianakis, Alan Carver, Maya Katz, J Randall Curtis, Robert G Holloway
Neuropalliative care is an emerging subspecialty in neurology and palliative care. On April 26, 2017, we convened a Neuropalliative Care Summit with national and international experts in the field to develop a clinical, educational, and research agenda to move the field forward. Clinical priorities included the need to develop and implement effective models to integrate palliative care into neurology and to develop and implement informative quality measures to evaluate and compare palliative approaches. Educational priorities included the need to improve the messaging of palliative care and to create standards for palliative care education for neurologists and neurology education for palliative specialists...
July 31, 2018: Neurology
https://www.readbyqxmd.com/read/29726623/contemporary-analysis-of-practicing-otolaryngologists
#9
Willard C Harrill, David E Melon, Merritt J Seshul, Marc S Katz, Adam M Zanation
OBJECTIVES/HYPOTHESIS: To investigate contemporary issues facing practicing otolaryngologists including workforce dynamics, ancillary service modeling, otolaryngic allergy integration, ambulatory surgery center utilization, and relevant certificate of need legislation. STUDY DESIGN: A cross-sectional survey analysis of academic and private practicing otolaryngologists in North and South Carolina in 2016. METHODS: A cross-sectional survey was e-mailed to 510 practicing otolaryngologists in North and South Carolina...
May 4, 2018: Laryngoscope
https://www.readbyqxmd.com/read/29542976/measurement-of-atmospheric-neutrino-oscillations-at-6-56-gev-with-icecube-deepcore
#10
M G Aartsen, M Ackermann, J Adams, J A Aguilar, M Ahlers, M Ahrens, I Al Samarai, D Altmann, K Andeen, T Anderson, I Ansseau, G Anton, C Argüelles, J Auffenberg, S Axani, H Bagherpour, X Bai, J P Barron, S W Barwick, V Baum, R Bay, J J Beatty, J Becker Tjus, K-H Becker, S BenZvi, D Berley, E Bernardini, D Z Besson, G Binder, D Bindig, E Blaufuss, S Blot, C Bohm, M Börner, F Bos, D Bose, S Böser, O Botner, J Bourbeau, F Bradascio, J Braun, L Brayeur, M Brenzke, H-P Bretz, S Bron, J Brostean-Kaiser, A Burgman, T Carver, J Casey, M Casier, E Cheung, D Chirkin, A Christov, K Clark, L Classen, S Coenders, G H Collin, J M Conrad, D F Cowen, R Cross, M Day, J P A M de André, C De Clercq, J J DeLaunay, H Dembinski, S De Ridder, P Desiati, K D de Vries, G de Wasseige, M de With, T DeYoung, J C Díaz-Vélez, V di Lorenzo, H Dujmovic, J P Dumm, M Dunkman, B Eberhardt, T Ehrhardt, B Eichmann, P Eller, P A Evenson, S Fahey, A R Fazely, J Felde, K Filimonov, C Finley, S Flis, A Franckowiak, E Friedman, T Fuchs, T K Gaisser, J Gallagher, L Gerhardt, K Ghorbani, W Giang, T Glauch, T Glüsenkamp, A Goldschmidt, J G Gonzalez, D Grant, Z Griffith, C Haack, A Hallgren, F Halzen, K Hanson, D Hebecker, D Heereman, K Helbing, R Hellauer, S Hickford, J Hignight, G C Hill, K D Hoffman, R Hoffmann, B Hokanson-Fasig, K Hoshina, F Huang, M Huber, K Hultqvist, M Hünnefeld, S In, A Ishihara, E Jacobi, G S Japaridze, M Jeong, K Jero, B J P Jones, P Kalaczynski, W Kang, A Kappes, T Karg, A Karle, U Katz, M Kauer, A Keivani, J L Kelley, A Kheirandish, J Kim, M Kim, T Kintscher, J Kiryluk, T Kittler, S R Klein, G Kohnen, R Koirala, H Kolanoski, L Köpke, C Kopper, S Kopper, J P Koschinsky, D J Koskinen, M Kowalski, K Krings, M Kroll, G Krückl, J Kunnen, S Kunwar, N Kurahashi, T Kuwabara, A Kyriacou, M Labare, J L Lanfranchi, M J Larson, F Lauber, D Lennarz, M Lesiak-Bzdak, M Leuermann, Q R Liu, L Lu, J Lünemann, W Luszczak, J Madsen, G Maggi, K B M Mahn, S Mancina, R Maruyama, K Mase, R Maunu, F McNally, K Meagher, M Medici, M Meier, T Menne, G Merino, T Meures, S Miarecki, J Micallef, G Momenté, T Montaruli, R W Moore, M Moulai, R Nahnhauer, P Nakarmi, U Naumann, G Neer, H Niederhausen, S C Nowicki, D R Nygren, A Obertacke Pollmann, A Olivas, A O'Murchadha, T Palczewski, H Pandya, D V Pankova, P Peiffer, J A Pepper, C Pérez de Los Heros, D Pieloth, E Pinat, M Plum, P B Price, G T Przybylski, C Raab, L Rädel, M Rameez, K Rawlins, I C Rea, R Reimann, B Relethford, M Relich, E Resconi, W Rhode, M Richman, S Robertson, M Rongen, C Rott, T Ruhe, D Ryckbosch, D Rysewyk, T Sälzer, S E Sanchez Herrera, A Sandrock, J Sandroos, S Sarkar, S Sarkar, K Satalecka, P Schlunder, T Schmidt, A Schneider, S Schoenen, S Schöneberg, L Schumacher, D Seckel, S Seunarine, J Soedingrekso, D Soldin, M Song, G M Spiczak, C Spiering, J Stachurska, M Stamatikos, T Stanev, A Stasik, J Stettner, A Steuer, T Stezelberger, R G Stokstad, A Stößl, N L Strotjohann, G W Sullivan, M Sutherland, I Taboada, J Tatar, F Tenholt, S Ter-Antonyan, A Terliuk, G Tešić, S Tilav, P A Toale, M N Tobin, S Toscano, D Tosi, M Tselengidou, C F Tung, A Turcati, C F Turley, B Ty, E Unger, M Usner, J Vandenbroucke, W Van Driessche, N van Eijndhoven, S Vanheule, J van Santen, M Vehring, E Vogel, M Vraeghe, C Walck, A Wallace, M Wallraff, F D Wandler, N Wandkowsky, A Waza, C Weaver, M J Weiss, C Wendt, J Werthebach, S Westerhoff, B J Whelan, K Wiebe, C H Wiebusch, L Wille, D R Williams, L Wills, M Wolf, J Wood, T R Wood, E Woolsey, K Woschnagg, D L Xu, X W Xu, Y Xu, J P Yanez, G Yodh, S Yoshida, T Yuan, M Zoll
We present a measurement of the atmospheric neutrino oscillation parameters using three years of data from the IceCube Neutrino Observatory. The DeepCore infill array in the center of IceCube enables the detection and reconstruction of neutrinos produced by the interaction of cosmic rays in Earth's atmosphere at energies as low as ∼5  GeV. That energy threshold permits measurements of muon neutrino disappearance, over a range of baselines up to the diameter of the Earth, probing the same range of L/E_{ν} as long-baseline experiments but with substantially higher-energy neutrinos...
February 16, 2018: Physical Review Letters
https://www.readbyqxmd.com/read/29429630/transcatheter-aortic-valve-replacement-in-patients-with-severe-mitral-or-tricuspid-regurgitation-at-extreme-risk-for-surgery
#11
Stephen H Little, Jeffrey J Popma, Neal S Kleiman, G Michael Deeb, Thomas G Gleason, Steven J Yakubov, Stan Checuti, Daniel O'Hair, Tanvir Bajwa, Mubashir Mumtaz, Brijeshwar Maini, Alan Hartman, Stanley Katz, Newell Robinson, George Petrossian, John Heiser, William Merhi, B Jane Moore, Shuzhen Li, David H Adams, Michael J Reardon
OBJECTIVES: Patients with symptomatic severe aortic stenosis and severe mitral regurgitation or severe tricuspid regurgitation were excluded from the major transcatheter aortic valve replacement trials. We studied these 2 subgroups in patients at extreme risk for surgery in the prospective, nonrandomized, single-arm CoreValve US Expanded Use Study. METHODS: The primary end point was all-cause mortality or major stroke at 1 year. A favorable medical benefit was defined as a Kansas City Cardiomyopathy Questionnaire overall summary score greater than 45 at 6 months and greater than 60 at 1 year and with a less than 10-point decrease from baseline...
May 2018: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29370166/expanding-molecular-diagnostics-of-helminthiasis-piloting-use-of-the-gpln-platform-for-surveillance-of-soil-transmitted-helminthiasis-and-schistosomiasis-in-ghana
#12
Lucas J Cunningham, John Odoom, Deborah Pratt, Linda Boatemaa, Nana Asante-Ntim, Keren Attiku, Bismarck Banahene, Mike Osei-Atweneboana, Jaco J Verweij, David Molyneux, Russell J Stothard, Emily R Adams
The efforts to control and eradicate polio as a global health burden have been successful to the point where currently only three countries now report endemic polio, and the number of cases of polio continues to decrease. The success of the polio programme has been dependant on a well-developed network of laboratories termed the global polio laboratory network (GPLN). Here we explore collaborative opportunities with the GPLN to target two of the 18 diseases listed as a neglected tropical diseases (NTD) namely soil transmitted helminthiasis (STH) and Schistosomiasis (SCH)...
January 2018: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/29321258/functional-variants-in-the-lrrk2-gene-confer-shared-effects-on-risk-for-crohn-s-disease-and-parkinson-s-disease
#13
Ken Y Hui, Heriberto Fernandez-Hernandez, Jianzhong Hu, Adam Schaffner, Nathan Pankratz, Nai-Yun Hsu, Ling-Shiang Chuang, Shai Carmi, Nicole Villaverde, Xianting Li, Manual Rivas, Adam P Levine, Xiuliang Bao, Philippe R Labrias, Talin Haritunians, Darren Ruane, Kyle Gettler, Ernie Chen, Dalin Li, Elena R Schiff, Nikolas Pontikos, Nir Barzilai, Steven R Brant, Susan Bressman, Adam S Cheifetz, Lorraine N Clark, Mark J Daly, Robert J Desnick, Richard H Duerr, Seymour Katz, Todd Lencz, Richard H Myers, Harry Ostrer, Laurie Ozelius, Haydeh Payami, Yakov Peter, John D Rioux, Anthony W Segal, William K Scott, Mark S Silverberg, Jeffery M Vance, Iban Ubarretxena-Belandia, Tatiana Foroud, Gil Atzmon, Itsik Pe'er, Yiannis Ioannou, Dermot P B McGovern, Zhenyu Yue, Eric E Schadt, Judy H Cho, Inga Peter
Crohn's disease (CD), a form of inflammatory bowel disease, has a higher prevalence in Ashkenazi Jewish than in non-Jewish European populations. To define the role of nonsynonymous mutations, we performed exome sequencing of Ashkenazi Jewish patients with CD, followed by array-based genotyping and association analysis in 2066 CD cases and 3633 healthy controls. We detected association signals in the LRRK2 gene that conferred risk for CD (N2081D variant, P = 9.5 × 10-10 ) or protection from CD (N551K variant, tagging R1398H-associated haplotype, P = 3...
January 10, 2018: Science Translational Medicine
https://www.readbyqxmd.com/read/29170450/interplay-between-notch1-and-notch3-promotes-emt-and-tumor-initiation-in-squamous-cell-carcinoma
#14
Mitsuteru Natsuizaka, Kelly A Whelan, Shingo Kagawa, Koji Tanaka, Veronique Giroux, Prasanna M Chandramouleeswaran, Apple Long, Varun Sahu, Douglas S Darling, Jianwen Que, Yizeng Yang, Jonathan P Katz, E Paul Wileyto, Devraj Basu, Yoshiaki Kita, Shoji Natsugoe, Seiji Naganuma, Andres J Klein-Szanto, J Alan Diehl, Adam J Bass, Kwok-Kin Wong, Anil K Rustgi, Hiroshi Nakagawa
Notch1 transactivates Notch3 to drive terminal differentiation in stratified squamous epithelia. Notch1 and other Notch receptor paralogs cooperate to act as a tumor suppressor in squamous cell carcinomas (SCCs). However, Notch1 can be stochastically activated to promote carcinogenesis in murine models of SCC. Activated form of Notch1 promotes xenograft tumor growth when expressed ectopically. Here, we demonstrate that Notch1 activation and epithelial-mesenchymal transition (EMT) are coupled to promote SCC tumor initiation in concert with transforming growth factor (TGF)-β present in the tumor microenvironment...
November 24, 2017: Nature Communications
https://www.readbyqxmd.com/read/29144463/a-single-cell-survey-of-the-small-intestinal-epithelium
#15
Adam L Haber, Moshe Biton, Noga Rogel, Rebecca H Herbst, Karthik Shekhar, Christopher Smillie, Grace Burgin, Toni M Delorey, Michael R Howitt, Yarden Katz, Itay Tirosh, Semir Beyaz, Danielle Dionne, Mei Zhang, Raktima Raychowdhury, Wendy S Garrett, Orit Rozenblatt-Rosen, Hai Ning Shi, Omer Yilmaz, Ramnik J Xavier, Aviv Regev
Intestinal epithelial cells absorb nutrients, respond to microbes, function as a barrier and help to coordinate immune responses. Here we report profiling of 53,193 individual epithelial cells from the small intestine and organoids of mice, which enabled the identification and characterization of previously unknown subtypes of intestinal epithelial cell and their gene signatures. We found unexpected diversity in hormone-secreting enteroendocrine cells and constructed the taxonomy of newly identified subtypes, and distinguished between two subtypes of tuft cell, one of which expresses the epithelial cytokine Tslp and the pan-immune marker CD45, which was not previously associated with non-haematopoietic cells...
November 16, 2017: Nature
https://www.readbyqxmd.com/read/29073412/national-sleep-foundation-s-sleep-time-duration-recommendations-methodology-and-results-summary
#16
Max Hirshkowitz, Kaitlyn Whiton, Steven M Albert, Cathy Alessi, Oliviero Bruni, Lydia DonCarlos, Nancy Hazen, John Herman, Eliot S Katz, Leila Kheirandish-Gozal, David N Neubauer, Anne E O'Donnell, Maurice Ohayon, John Peever, Robert Rawding, Ramesh C Sachdeva, Belinda Setters, Michael V Vitiello, J Catesby Ware, Paula J Adams Hillard
OBJECTIVE: The objective was to conduct a scientifically rigorous update to the National Sleep Foundation's sleep duration recommendations. METHODS: The National Sleep Foundation convened an 18-member multidisciplinary expert panel, representing 12 stakeholder organizations, to evaluate scientific literature concerning sleep duration recommendations. We determined expert recommendations for sufficient sleep durations across the lifespan using the RAND/UCLA Appropriateness Method...
March 2015: Sleep Health
https://www.readbyqxmd.com/read/29073398/national-sleep-foundation-s-updated-sleep-duration-recommendations-final-report
#17
Max Hirshkowitz, Kaitlyn Whiton, Steven M Albert, Cathy Alessi, Oliviero Bruni, Lydia DonCarlos, Nancy Hazen, John Herman, Paula J Adams Hillard, Eliot S Katz, Leila Kheirandish-Gozal, David N Neubauer, Anne E O'Donnell, Maurice Ohayon, John Peever, Robert Rawding, Ramesh C Sachdeva, Belinda Setters, Michael V Vitiello, J Catesby Ware
OBJECTIVE: To make scientifically sound and practical recommendations for daily sleep duration across the life span. METHODS: The National Sleep Foundation convened a multidisciplinary expert panel (Panel) with broad representation from leading stakeholder organizations. The Panel evaluated the latest scientific evidence and participated in a formal consensus and voting process. Then, the RAND/UCLA Appropriateness Method was used to formulate sleep duration recommendations...
December 2015: Sleep Health
https://www.readbyqxmd.com/read/28888303/fat-grafting-for-burn-traumatic-and-surgical-scars
#18
REVIEW
Rafi Fredman, Adam J Katz, Charles Scott Hultman
Fat grafting provides a reliable modality with expanding usefulness in reconstructive plastic surgery. Owing to its mechanical and theorized regenerative properties, adipose tissue can improve scar qualities and scar related symptoms when grafted adjacent to or within a scar. In this article, the literature describing the effect of fat grafting on various types of scars, current scientific understanding of fat grafting for scars, and our current approach to the management of problematic burn scars are reviewed...
October 2017: Clinics in Plastic Surgery
https://www.readbyqxmd.com/read/28754328/age-related-levels-of-fecal-m2-pyruvate-kinase-in-children-with-cystic-fibrosis-and-healthy-children-0-to-10years-old
#19
Millie Garg, Steven T Leach, Tamara Pang, Bronwen Needham, Michael J Coffey, Tamarah Katz, Roxanne Strachan, John Widger, Penelope Field, Yvonne Belessis, Sandra Chuang, Andrew S Day, Adam Jaffe, Chee Y Ooi
BACKGROUND: The pathogenesis of gut inflammation, bacterial dysbiosis and increased rates of malignancy in CF is unclear. Fecal M2-pyruvate kinase (M2-PK) is a biomarker indicative of cellular proliferation that may be raised in intestinal malignancy and inflammation. Biomarkers, including M2-PK, may be useful in assessing effects of novel therapies on the gastrointestinal tract. METHODS: M2-PK was measured in stools collected from patients with CF and HC (0-10years)...
January 2018: Journal of Cystic Fibrosis: Official Journal of the European Cystic Fibrosis Society
https://www.readbyqxmd.com/read/28589954/wnt10a-mutation-causes-ectodermal-dysplasia-by-impairing-progenitor-cell-proliferation-and-klf4-mediated-differentiation
#20
Mingang Xu, Jeremy Horrell, Melinda Snitow, Jiawei Cui, Heather Gochnauer, Camille M Syrett, Staci Kallish, John T Seykora, Fei Liu, Dany Gaillard, Jonathan P Katz, Klaus H Kaestner, Brooke Levin, Corinne Mansfield, Jennifer E Douglas, Beverly J Cowart, Michael Tordoff, Fang Liu, Xuming Zhu, Linda A Barlow, Adam I Rubin, John A McGrath, Edward E Morrisey, Emily Y Chu, Sarah E Millar
Human WNT10A mutations are associated with developmental tooth abnormalities and adolescent onset of a broad range of ectodermal defects. Here we show that β-catenin pathway activity and adult epithelial progenitor proliferation are reduced in the absence of WNT10A, and identify Wnt-active self-renewing stem cells in affected tissues including hair follicles, sebaceous glands, taste buds, nails and sweat ducts. Human and mouse WNT10A mutant palmoplantar and tongue epithelia also display specific differentiation defects that are mimicked by loss of the transcription factor KLF4...
June 7, 2017: Nature Communications
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