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mortality atrial fibrillation

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https://www.readbyqxmd.com/read/30342698/usefulness-of-the-cha-2-ds-2-vasc-score-to-predict-the-risk-of-sudden-cardiac-death-and-ventricular-arrhythmias-in-patients-with-atrial-fibrillation
#1
Ling Kuo, Tze-Fan Chao, Chia-Jen Liu, Su-Jung Chen, Ta-Chuan Tuan, Yenn-Jiang Lin, Shih-Lin Chang, Li-Wei Lo, Yu-Feng Hu, Fa-Po Chung, Jo-Nan Liao, Tzeng-Ji Chen, Gregory Y H Lip, Shih-Ann Chen
Sudden cardiac death (SCD), the most devastating manifestation of ventricular arrhythmias (VAs), is the leading cause of mortality in patients with atrial fibrillation (AF). We hypothesized that the CHA2 DS2 -VASc score, consisting of age and several clinical risk factors, could be used to estimate the individual risk of SCD/VAs for AF patients. From year 2000 to 2011, 288,181 newly-diagnosed AF patients without antecedent SCD/VAs were identified from "Taiwan National Health Insurance Research Database...
September 13, 2018: American Journal of Cardiology
https://www.readbyqxmd.com/read/30341846/study-of-rhythm-disturbances-in-acute-myocardial-infarction
#2
Anjalee Chiwhane, Pradeep
Introduction: Cardiac rhythm disturbances are common presentation in acute coronary syndromes and are cause of frequent serious complications in acute myocardial infarction (AMI). However due to availability of early reperfusion therapy and primary angioplasty, arrhythmias have cause a reduction in mortality. Arrhythmias are key events before, during or after the occurrence of acute MI. There are few clinical studies describing the types of arryhthmias, their correlation with the clinical profile of acute MI and effect on outcomes...
January 2018: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/30337081/prediction-of-paroxysmal-atrial-fibrillation-a-machine-learning-based-approach-using-combined-feature-vector-and-mixture-of-expert-classification-on-hrv-signal
#3
Elias Ebrahimzadeh, Maede Kalantari, Mohammadamin Joulani, Reza Shahrokhi Shahraki, Farahnaz Fayaz, Fereshteh Ahmadi
BACKGROUND AND OBJECTIVE: Paroxysmal Atrial Fibrillation (PAF) is one of the most common major cardiac arrhythmia. Unless treated timely, PAF might transform into permanent Atrial Fibrillation leading to a high rate of morbidity and mortality. Therefore, increasing attention has been directed towards prediction of PAF, to enable early detection and prevent further progression of the disease. Notwithstanding the pharmacological and electrical treatments, a validated method to predict the onset of PAF is yet to be developed...
October 2018: Computer Methods and Programs in Biomedicine
https://www.readbyqxmd.com/read/30336847/remote-ischaemic-conditioning-for-prevention-of-acute-kidney-injury-after-valvular-heart-surgery-a-randomised-controlled-trial
#4
J W Song, W K Lee, S Lee, J K Shim, H J Kim, Y L Kwak
BACKGROUND: Repeated remote ischaemic conditioning (RIC) during weaning from cardiopulmonary bypass and in the early postoperative period may confer protection against acute kidney injury (AKI). We evaluated the effect of repeated RIC on the incidence of AKI in patients undergoing valvular heart surgery. METHODS: Patients were randomised into either the RIC (n=120) or control (n=124) group. A pneumatic tourniquet was placed on each patient's thigh. Upon removal of the aortic cross-clamp, three cycles of inflation for 5 min at 250 mm Hg (with 5 min intervals) were applied in the RIC group...
November 2018: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/30334980/a-case-report-of-unexpected-sudden-cardiac-death-due-to-aortic-rupture-following-laparoscopic-appendectomy
#5
Chunghee Joo, Joo-Won Min, Giyong Noh, Jaeho Seo
INTRODUCTION: Aortic dissection is a very rare but life-threatening condition associated with a high mortality. Unexpected sudden cardiac death due to aortic rupture following laparoscopic appendectomy is very rare and may be difficult to diagnose. However, early diagnosis of aortic dissection is essential for the timely treatment and outcome of aortic dissection. CASE PRESENTATION: A 50-year-old man underwent a laparoscopic appendectomy. Postoperatively, the patient complained of dyspnea and chest pain...
October 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/30334439/management-of-atrial-fibrillation-easy-as-abc
#6
Maria Mahmood, Gregory Y Lip
Atrial fibrillation (AF) is the commonest sustained arrhythmia with increasing incidence worldwide. AF is a major cause of morbidity (resulting from heart failure, stroke and hospitalisation) and mortality. The aim of primary and specialist care is to improve patient outcome through early detection of AF and optimal clinical management. In this review, we present the ABC Pathway for the holistic, integrated management of patients diagnosed with AF: "A" Avoid stroke with Anticoagulation; "B" for Better symptom management with patient-centred, symptom directed decisions on rate or rhythm control; and "C" Cardiovascular and comorbidity risk reduction, including lifestyle factors and psychological morbidity...
October 11, 2018: Minerva Medica
https://www.readbyqxmd.com/read/30334313/the-safety-of-noacs-in-atrial-fibrillation-patient-subgroups-a-narrative-review
#7
Gregory Y H Lip
AIM: Four non-vitamin K oral anticoagulants (NOACs) have been evaluated in clinical trials for the prevention of stroke in patients with atrial fibrillation (AF). Although each of the NOACs have been shown to be at least non-inferior to warfarin for efficacy and safety outcomes, controversy remains over the relative safety of each NOAC in patient subgroups. This narrative review provides an overview of phase III data on NOAC trials for the prevention of stroke in AF, with a focus on reporting the safety of each agent in key patient subgroups based on age, gender, accumulated risk factors, and primary or secondary prevention of stroke...
October 17, 2018: International Journal of Clinical Practice
https://www.readbyqxmd.com/read/30333348/predictors-of-acute-kidney-injury-in-patients-undergoing-adult-cardiac-surgery
#8
Sreja Gangadharan, K R Sundaram, Senthilvelan Vasudevan, B Ananthakrishnan, Rakhi Balachandran, Abraham Cherian, Praveen Kerala Varma, Luis Bakero Gracia, K Murukan, Ashish Madaiker, Rajesh Jose, Rakesh Seetharaman, Kirun Gopal, Sujatha Menon, M Thushara, Reshmi Liza Jose, G Deepak, Sudheer Babu Vanga, Aveek Jayant
Background: Acute kidney injury (AKI) after cardiac surgery (CS) is not uncommon and has serious effects on mortality and morbidity. A majority of patients suffer mild forms of AKI. There is a paucity of Indian data regarding this important complication after CS. Aims and Objectives: The primary objective was to study the incidence of AKI associated with CS in an Indian study population. Secondary objectives were to describe the risk factors associated with AKI-CS in our population and to generate outcome data in patients who suffer this complication...
October 2018: Annals of Cardiac Anaesthesia
https://www.readbyqxmd.com/read/30332561/opportunities-for-micrornas-in-the-crowded-field-of-cardiovascular-biomarkers
#9
Perry V Halushka, Andrew J Goodwin, Marc K Halushka
Cardiovascular diseases exist across all developed countries societies. Biomarkers that can predict or diagnose diseases early in their pathogeneses can reduce their morbidity and mortality in afflicted individuals. microRNAs are small regulatory RNAs that modulate translation and have been identified as potential fluid-based biomarkers across numerous maladies. We describe the current state of cardiovascular disease biomarkers across a range of diseases, including myocardial infarction, acute coronary syndrome, myocarditis, hypertension, heart failure, heart transplantation, aortic stenosis, diabetic cardiomyopathy, atrial fibrillation, and sepsis...
October 17, 2018: Annual Review of Pathology
https://www.readbyqxmd.com/read/30329031/atrial-fibrillation-hospitalization-mortality-and-therapy
#10
Roy M John, Gregory F Michaud, William G Stevenson
No abstract text is available yet for this article.
October 16, 2018: European Heart Journal
https://www.readbyqxmd.com/read/30328215/haemodynamic-mechanisms-and-long-term-prognostic-impact-of-pulmonary-hypertension-in-patients-with-severe-aortic-stenosis-undergoing-valve-replacement
#11
Lukas Weber, Hans Rickli, Philipp K Haager, Lucas Joerg, Daniel Weilenmann, Roman Brenner, Maurizio Taramasso, Philipp Baier, Francesco Maisano, Micha T Maeder
AIMS: We aimed to investigate the prevalence, detailed invasive haemodynamics, and prognostic impact of pulmonary hypertension (PH) in severe aortic stenosis (AS). METHODS AND RESULTS: We studied 503 patients (mean age 74 ± 10 years) with severe AS (indexed aortic valve area 0.4 ± 0.1 cm2 /m2 , left ventricular ejection fraction 57 ± 12%) undergoing left and right heart catheterization prior to aortic valve replacement. Median follow-up was 3...
October 17, 2018: European Journal of Heart Failure
https://www.readbyqxmd.com/read/30328129/baseline-atrial-fibrillation-is-associated-with-contrast-induced-nephropathy-after-cardiac-catheterization-in-coronary-artery-disease-systemic-review-and-meta-analysis
#12
Narut Prasitlumkum, Chanavuth Kanitsoraphan, Veraprapas Kittipibul, Pattara Rattanawong, Pakawat Chongsathidkiet, Wisit Cheungpasitporn
INTRODUCTION: Atrial fibrillation (AF) is the most common arrhythmia, independently associated with significant mortality and morbidity. Recent studies suggest that AF is potentially associated with contrast-induced nephropathy (CIN) in patients with Coronary artery disease (CAD) undergoing catheterization. However, the association was not conclusive. Thus, we assessed the association between AF in patients with CAD and CIN by a systematic review of the literature and a meta-analysis...
October 17, 2018: Clinical Cardiology
https://www.readbyqxmd.com/read/30327694/plasma-markers-of-myocardial-inflammation-at-isolated-atrial-fibrillation
#13
Svetlana Ivanovna Sazonova, Julia Nikolaevna Ilushenkova, Roman Efimovich Batalov, Anna Mihaylovna Gusakova, Julia Vladimirovna Saranchina, Julia Viktorovna Rogovskaya, Sergey Valentinovich Popov
Background: Atrial fibrillation (AF) is one of the widest spread forms of arrhythmia, which is associated with the increased mortality and thromboembolic complications. To date, the involvement of renin-angiotensin-aldosterone system and immunomediators of inflammation into the mechanisms of development and maintenance of isolated AF is not clear. Specificity of their changes with respect to the latent myocarditis at AF is not proved. Methods: In 96 patients with persistent isolated atrial fibrillation (IsAF), scheduled for radiofrequency ablation and endomyocardial biopsy (EMB), and in 20 healthy volunteers (HVT), levels of plasma tumor necrosis factor-α (TNF-α), interleukin (IL)-1β, IL-6, IL-8, IL-10, fatty acid-binding protein (FABP), neopterin, C-reactive protein (CRP) were determined by ELISA, level of aldosterone and the renin activity were determined by radioimmunoassay...
October 2018: Journal of Arrhythmia
https://www.readbyqxmd.com/read/30327128/subclinical-hypothyroidism-and-coronary-revascularization-after-coronary-artery-bypass-grafting
#14
Sung Hye Kong, Ji Won Yoon, Sang Yoon Kim, Tae Jung Oh, Kay-Hyun Park, Joong Haeng Choh, Young Joo Park, Cheong Lim
We aimed to investigate long-term cardiovascular sequelae after coronary artery bypass grafting (CABG) in patients with subclinical hypothyroidism (SCH). All-cause and cardiovascular-related mortality, and cardiovascular events were retrospectively reviewed in 222 euthyroid and 36 SCH patients who underwent CABG. During a mean follow-up period of 8.2 ± 4.1years, there were 90 incidents of all-cause deaths, 20 cardiovascular-related deaths, 70 major cardiovascular adverse events, 6 myocardial infarctions, 12 unstable anginas, 31 strokes, 23 hospitalizations due to heart failure, 15 atrial fibrillation (AF) events, and 27 coronary revascularizations...
September 7, 2018: American Journal of Cardiology
https://www.readbyqxmd.com/read/30325423/prognostic-implications-of-atrial-fibrillation-in-heart-failure-with-reduced-mid-range-and-preserved-ejection-fraction-a-report-from-14-964-patients-in-the-european-society-of-cardiology-heart-failure-long-term-registry
#15
Barak Zafrir, Lars H Lund, Cecile Laroche, Frank Ruschitzka, Maria G Crespo-Leiro, Andrew J S Coats, Stefan D Anker, Gerasimos Filippatos, Petar M Seferovic, Aldo P Maggioni, Manuel De Mora Martin, Lech Polonski, José Silva-Cardoso, Offer Amir
Aim: To investigate the characteristics long-term prognostic implications (up to ∼2.2 years) of atrial fibrillation (AF) compared to sinus rhythm (SR), between acute and chronic heart failure (HF) with reduced (HFrEF < 40%), mid-range (HFmrEF 40-49%), and preserved (HFpEF ≥ 50%) ejection fraction (EF). Methods and results: Data from the observational, prospective, HF long-term registry of the European Society of Cardiology were analysed. A total of 14 964 HF patients (age 66 ± 13 years, 67% male; 53% HFrEF, 21% HFmrEF, 26% HFpEF) were enrolled...
October 15, 2018: European Heart Journal
https://www.readbyqxmd.com/read/30322760/clinical-features-of-post-cardiac-injury-syndrome-following-catheter-ablation-of-arrhythmias-systematic-review-and-additional-cases
#16
Wei Li, Jian Sun, Ying Yu, Zhi-Quan Wang, Peng-Pai Zhang, Kai Guo, Man-Tian Chen, Yi-Gang Li
BACKGROUND: Post cardiac injury syndrome (PCIS) is a troublesome but not uncommon complication following catheter ablation of arrhythmias. We aimed to study the clinical features of ablation-associated PCIS. METHODS: For this purpose, we conducted a computerised literature search that identified 19 published cases, and we additionally included another 2 new cases from our centres. Twenty-one cases of PCIS following ablation were analysed. RESULTS: Among the 21 cases, PCIS most commonly occurred after atrial flutter/fibrillation (AFL/AF) ablation (71...
October 7, 2018: Heart, Lung & Circulation
https://www.readbyqxmd.com/read/30318902/the-efficacy-and-safety-of-non-vitamin-k-antagonist-oral-anticoagulants-in-patients-with-atrial-fibrillation-and-coronary-artery-disease-a-meta-analysis-of-randomized-trials
#17
Thomas A Zelniker, Christian T Ruff, Elliott M Antman, Robert P Giugliano
BACKGROUND: Patients with atrial fibrillation and concomitant coronary artery disease (CAD) are at higher risk for myocardial infarction or cardiovascular death, often require antiplatelet therapy and are therefore exposed to an increased risk of bleeding. This meta-analysis aimed to compare the efficacy and safety profile of non-vitamin K antagonist oral anticoagulants (NOACs) with warfarin in patients with atrial fibrillation and concomitant CAD. MATERIALS AND METHODS: We performed a trial-level meta-analysis of CAD subgroups from four trials of NOAC versus warfarin in patients with atrial fibrillation, comparing the primary trial endpoints (efficacy: stroke or systemic embolic event; safety: International Society on Thrombosis and Haemostasis major bleeding) in patients with versus those without CAD, and used interaction testing to assess for treatment effect modification...
October 15, 2018: European Heart Journal. Acute Cardiovascular Care
https://www.readbyqxmd.com/read/30318417/impact-of-baseline-atrial-fibrillation-on-outcomes-among-women-who-underwent-contemporary-transcatheter-aortic-valve-implantation-from-the-win-tavi-registry
#18
Paul Guedeney, Alaide Chieffo, Clayton Snyder, Julinda Mehilli, Anna Sonia Petronio, Bimmer E Claessen, Samantha Sartori, Thierry Lefèvre, Patrizia Presbitero, Piera Capranzano, Didier Tchétché, Alessandro Iadanza, Gennaro Sardella, Nicolas M Van Mieghem, Jaya Chandrasekhar, Birgit Vogel, Sabato Sorrentino, Deborah N Kalkman, Emanuele Meliga, Nicolas Dumonteil, Chiara Fraccaro, Daniela Trabattoni, Ghada Mikhail, Maria Cruz Ferrer, Christoph Naber, Peter Kievit, Usman Baber, Samin Sharma, Marie Claude Morice, Roxana Mehran
Pre-existing atrial fibrillation (AF) is common among patients who underwent transcatheter aortic valve implantation (TAVI) and has been associated with adverse outcomes. The specific impact of AF at baseline in women who underwent TAVI, however, remains unknown. The Women's International Transcatheter Aortic Valve Implantation is a prospective, multinational registry evaluating the safety and performance of contemporary TAVI in women in 19 centers between January 2013 and December 2015. Patients with available electrocardiogram at baseline were compared according to the presence of AF...
September 8, 2018: American Journal of Cardiology
https://www.readbyqxmd.com/read/30318188/left-atrial-volume-index-can-it-provide-additional-prognostic-information-in-st-segment-elevation-myocardial-infarction-treated-with-primary-percutaneous-coronary-intervention
#19
Filipa Cordeiro, Pedro Silva Mateus, Sílvia Leão, Miguel Moz, Joana Trigo, Catarina Ferreira, Sofia Silva Carvalho, Alberto Ferreira, José Ilídio Moreira
INTRODUCTION: We sought to assess the prognostic impact of left atrial (LA) size on long-term outcomes of ST-segment elevation myocardial infarction (STEMI). METHODS: We studied 200 consecutive patients admitted to a single center between January 2010 and December 2014 with non-fatal STEMI treated with primary percutaneous coronary intervention (pPCI) who underwent a comprehensive echocardiographic examination at discharge. LA volume was estimated by the area-length method...
October 11, 2018: Portuguese Journal of Cardiology: An Official Journal of the Portuguese Society of Cardiology
https://www.readbyqxmd.com/read/30316854/robotic-assisted-surgical-ablation-of-atrial-fibrillation-combined-with-mitral-valve-surgery
#20
Min Ho Ju, Jin Hyung Huh, Chee-Hoon Lee, Ho Jin Kim, Hyung Gon Je, Joon Bum Kim, Sung-Ho Jung, Jae Won Lee
BACKGROUND: Data on robotic-assisted surgical atrial fibrillation (AF) ablation in patients undergoing mitral valve (MV) surgeries are lacking. This study aimed to evaluate early and late outcomes following robotic-assisted ablation of AF combined with MV surgery. METHODS: Between 2007 and 2017, this study enrolled 94 patients (53.9±12.7 years; 67 males) undergoing AF ablation using an argon-based flexible cryoablation system during robotic-assisted MV surgery...
October 11, 2018: Annals of Thoracic Surgery
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