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mortality atrial fibrillation

Ali J Khiabani, Taylan Adademir, Richard B Schuessler, Spencer J Melby, Marc R Moon, Ralph J Damiano
Untreated atrial fibrillation is associated with an increased risk of all-cause mortality and morbidity. Despite the current guidelines recommending surgical ablation of atrial fibrillation at the time of coronary artery bypass surgery, most patients with concomitant atrial fibrillation and coronary artery disease do not receive surgical ablation for their atrial fibrillation. This review reports the efficacy of different surgical ablation techniques used for the treatment of atrial fibrillation during coronary artery bypass...
November 30, 2018: Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery
Zhiyong Qian, Fengwei Zou, Yao Wang, Yuanhao Qiu, Xing Chen, Hai Jiang, Xiaofeng Hou
BACKGROUND: Cardiac resynchronization therapy (CRT) is the standard-of-care therapy for the patients with heart failure and left ventricular (LV) dyssynchrony. However, approximately 30% of patients show no response. Recent studies have shown that His bundle pacing (HBP) could be an alternative for the patients with CRT indications. The purpose of this study was to evaluate the efficacy of HBP in patients with heart failure. METHODS: We searched PubMed and Embase databases for studies evaluating HBP in patients with heart failure and LV dyssynchrony...
December 4, 2018: Pacing and Clinical Electrophysiology: PACE
Varunsiri Atti, Mahesh Anantha-Narayanan, Mohit K Turagam, Scott Koerber, Sunil Rao, Juan F Viles-Gonzalez, Rakesh M Suri, Poonam Velagapudi, Dhanunjaya Lakkireddy, David G Benditt
AIM: To evaluate the safety and efficacy of surgical left atrial appendage occlusion (s-LAAO) during concomitant cardiac surgery. METHODS: We performed a comprehensive literature search through May 31st 2018 for all eligible studies comparing s-LAAO vs no occlusion in patients undergoing cardiac surgery. Clinical outcomes during follow-up included: embolic events, stroke, all-cause mortality, atrial fibrillation (AF), reoperation for bleeding and postoperative complications...
November 26, 2018: World Journal of Cardiology
Sina Bagheri, Shahrbanoo Shahbazi, Masih Shafa, Afshin Borhani-Haghighi, Mahsa Kiani, Mohammad Mahdi Sagheb
Background: Remote ischemic preconditioning (RIPC) protects other organs from subsequent lethal ischemic injury, but uncertainty remains. We investigated if RIPC could prevent acute kidney injury (AKI) in patients undergoing coronary artery bypass graft (CABG) surgery. Methods: This parallel-group, double-blind, randomized, controlled trial was done on adults undergoing elective or urgent on-pump CABG surgery from 2013 to 2017 in Shiraz, Iran. Patients were allocated to RIPC or control groups through permuted blocking...
November 2018: Iranian Journal of Medical Sciences
Sohaib A Virk, Richard G Bennett, Clara Chow, Prashanthan Sanders, Jonathan M Kalman, Stuart Thomas, Saurabh Kumar
BACKGROUND: Catheter ablation (CA) is highly efficacious for symptomatic atrial fibrillation (AF) but data predominantly comes from patients with preserved ventricular function. We performed an updated systematic review and meta-analysis of randomised controlled trials (RCT) comparing CA versus medical therapy for AF associated with heart failure (HF). METHODS: Medline, EMBASE, and Cochrane Central Register of Controlled Trials (CENTRAL) were searched for RCTs reporting clinical outcomes of CA versus medical therapy for AF in HF patients with ≥6 months' follow-up (atrioventricular-node ablation/device therapy studies excluded)...
November 17, 2018: Heart, Lung & Circulation
Seng Chan You, Min Ho An, Dukyong Yoon, Ga-Young Ban, Pil-Sung Yang, Hee Tae Yu, Rae Woong Park, Boyoung Joung
BACKGROUND: Rate-control medications are considered first-line treatment for patients with atrial fibrillation (AF). However, obstructive lung disease (OLD), a condition prevalent in those with AF, often makes it difficult to use those medications because of the lack of studies on new-onset AF in patients with OLD. OBJECTIVE: The purpose of this study was to investigate clinical outcomes after administration of each class of rate-control medication in patients with concomitant AF and OLD (AF-OLD)...
December 2018: Heart Rhythm: the Official Journal of the Heart Rhythm Society
Seungbong Han, Gyung-Min Park, Yong-Giun Kim, Ki Won Hwang, Jae-Hyung Roh, Ki-Bum Won, Soe Hee Ann, Shin-Jae Kim, Sang-Gon Lee
Although the prevalence of atrial fibrillation (AF) and percutaneous coronary intervention (PCI) are increasing in Asia, there is a paucity of data concerning the effect of AF in Asian patients undergoing PCI with drug-eluting stents (DESs). Furthermore, the majority of previous studies investigating the effect of AF on prognosis following PCI have exclusively evaluated patients with myocardial infarction (MI). We aimed to evaluate the effect of AF on clinical outcomes of Asian patients undergoing PCI with DES for coronary artery disease (CAD) excluding acute MI...
November 2018: Medicine (Baltimore)
Jelle C L Himmelreich, Wim A M Lucassen, Martijn Heugen, Patrick M M Bossuyt, Hanno L Tan, Ralf E Harskamp, Faridi S van Etten-Jamaludin, Henk C P M van Weert
Aims: Premature atrial contractions (PACs) are a common cardiac phenomenon, traditionally considered to be of little clinical significance. Recent studies, however, suggest that PACs are associated with atrial fibrillation (AF), as well as ischaemic stroke, transient ischaemic attack, and mortality. This systematic review aims to investigate the association between PACs on standard electrocardiogram (ECG) as well as PAC-count on Holter monitor and future detection of AF, brain ischaemia, and all-cause mortality in patients without a history of AF...
December 1, 2018: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
Tyler J Mouw, Jennifer Lu, Meghan Woody-Fowler, John Ashcraft, Joseph Valentino, Peter DiPasco, Joshua Mammen, Mazin Al-Kasspooles
Background: Liver resection in conjunction with partial colectomy for colon cancer is considered acceptable treatment for isolated metastasis to the liver. This method is unstudied in patients undergoing cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) for carcinomatosis due to colon cancer and high grade appendiceal cancer. Methods: A retrospective chart review included patients from 2005 to 2016 undergoing CRS/HIPEC. Cancers other than colorectal adenocarcinoma and high grade appendiceal carcinoma were excluded...
October 2018: Journal of Gastrointestinal Oncology
Heather Smith, Ching Yeung, Stephen Gowing, Mouhannad Sadek, Donna Maziak, Sebastien Gilbert, Farid Shamji, Patrick Villeneuve, Sudhir Sundaresan, Andrew Seely
Atrial fibrillation (AF) is the most common sustained arrhythmia after non-cardiac thoracic surgery and is associated with a significant increase in perioperative morbidity, intensive care unit (ICU) admission, and mortality. Practical guidance is needed to assist clinicians in managing this critical issue and direct further research. Here we aim to provide a synoptic review and analysis of the literature to distil practical recommendations for prediction, prevention and management of post-operative atrial fibrillation (POAF) suitable for clinical application and further evaluation...
November 2018: Journal of Thoracic Disease
Stephane Arques
Atrial fibrillation is the most common cardiac rhythm disorder observed in clinical practice. It carries high morbidity and mortality rates, primarily related to heart failure, stroke and death. Validation of noninvasive markers in the diagnosis of heart failure with preserved ejection fraction and risk stratification is relevant in this clinical setting. The spectral tissue Dopplerderived E/e' ratio is a simple and reproducible index, which has been validated in noninvasive assessment of left ventricular diastolic pressures, regardless of rhythm...
August 2018: Journal of Atrial Fibrillation
Anna Tomaszuk-Kazberuk, Dimitrios Nikas, Paulina Lopatowska, Elzbieta Młodawska, Jolanta Malyszko, Hanna Bachorzewska-Gajewska, Slawomir Dobrzycki, Bożena Sobkowicz, Ioannis Goudevenos
BACKGROUND/AIMS: Several studies have implicated atrial fibrillation (AF) as a contributing factor in chronic kidney disease (CKD) and cardiovascular events. The prevalence of coronary artery disease (CAD) in patients with AF varies substantially from 17% to 46.5%. There are only few studies concerning renal function in population with AF undergoing coronary angiography. The aim of the present study was to assess which type of AF is dominant in CKD population scheduled for coronary angiography and if it can influence patients' outcome, the association between renal impairment and the type of coronary procedures in AF patients and the influence of renal function on in-hospital mortality...
November 30, 2018: Kidney & Blood Pressure Research
Sabrina Nolan, Kristian B Filion, Renee Atallah, Emmanuel Moss, Pauline Reynier, Mark J Eisenberg
BACKGROUND: Hybrid coronary revascularization (HCR) has emerged as a potential alternative to complete coronary artery bypass graft (CABG) surgery. However, the efficacy and safety of HCR vs CABG remain unclear. We therefore conducted a systematic review and meta-analysis to compare these interventions. METHODS: We systematically searched PubMed, MEDLINE (via Ovid), EMBASE (via Ovid), Cochrane Library of Clinical Trials, and the Web of Science for studies comparing HCR to CABG in patients with multivessel coronary artery disease...
December 2018: Journal of Invasive Cardiology
Mike Saji, Ryosuke Highchi, Nobuo Iguchi, Jun Shimuzu, Tetsuya Tobaru, Shuichiro Takanashi, Morimasa Takayama, Mitsuaki Isobe
BACKGROUND: Transcatheter aortic valve replacement (TAVR) for patients with rheumatic heart disease (RHD) has not been well-known. This study aimed to assess characteristics and computed tomography (CT) findings of the aortic valve in old patients with RHD and to investigate the safety and efficacy in the patients who underwent TAVR. METHODS AND RESULTS: Of 352 consecutive patients with severe aortic stenosis (AS) who underwent TAVR at the Sakakibara Heart Institute between 2013 and 2016, 10 patients (2...
November 16, 2018: International Journal of Cardiology
Alexander C Perino, George C Leef, Andrew Cluckey, Fahd N Yunus, Mariam Askari, Paul A Heidenreich, Sanjiv M Narayan, Paul J Wang, Mintu P Turakhia
BACKGROUND: Approaches, tools, and technologies for atrial fibrillation (AF) ablation have evolved significantly since its inception. We sought to characterize secular trends in AF ablation success rates. METHODS: We performed a systematic review and meta-analysis of AF ablation from January 1, 1990, to August 1, 2016, searching PubMed, Scopus, and Cochrane databases. Major exclusion criteria were insufficient outcome reporting and ablation strategies that were not prespecified and uniform...
October 29, 2018: American Heart Journal
Shoroq M Altawalbeh, Osama Y Alshogran, Kenneth J Smith
BACKGROUND: Warfarin use for stroke prevention in atrial fibrillation (AF) patients with chronic kidney disease is debated. Apixaban was shown to be safer than warfarin, with superior reduction in the risk of stroke, systemic embolism, mortality, and major bleeding irrespective of kidney function. OBJECTIVES: To evaluate the cost-utility of apixaban compared with warfarin in AF patients at different levels of kidney function. METHODS: A Markov model was used to estimate the cost effectiveness of apixaban compared with warfarin in AF patients at three levels of kidney function: estimated glomerular filtration rate (eGFR) of more than 80 ml/min, 50 to 80 ml/min, and 50 ml/min or less...
December 2018: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
César Caro Martínez, Ginés Elvira Ruiz, Pedro J Flores Blanco, Juan José Cerezo Manchado, Helena Albendín Iglesias, Alejandro Lova Navarro, Francisco Arregui Montoya, Arcadio García Alberola, Domingo Andrés Pascual Figal, José Luis Bailén Lorenzo, Sergio Manzano Fernández
INTRODUCTION AND OBJECTIVES: Valvular heart disease in patients with atrial fibrillation included in clinical trials with direct oral anticoagulants (DOAC) is common and is associated with worse prognosis. The aim of this study was to evaluate the prevalence of valvular heart disease and its influence on clinical events in real-world clinical practice. METHODS: We conducted a retrospective multicenter registry including 2297 consecutive patients with nonvalvular atrial fibrillation initiating DOAC between January 2013 and December 2016...
November 26, 2018: Revista Española de Cardiología
Dominik Linz, Adrian D Elliott, Mathias Hohl, Varun Malik, Ulrich Schotten, Dobromir Dobrev, Stanley Nattel, Michael Böhm, John Floras, Dennis H Lau, Prashanthan Sanders
Atrial fibrillation is the most common sustained arrhythmia and is associated with significant morbidity and mortality. The autonomic nervous system has a significant role in the milieu predisposing to the triggers, perpetuators and substrate for atrial fibrillation. It has direct electrophysiological effects and causes alterations in atrial structure. In a significant portion of patients with atrial fibrillation, the autonomic nervous system activity is likely a composite of reflex excitation due to atrial fibrillation itself and contribution of concomitant risk factors such as hypertension, obesity and sleep-disordered breathing...
November 18, 2018: International Journal of Cardiology
Nuray Kahraman Ay, Asim Enhos, Yasin Ay, Nijad Bakhshaliyev, Aydin Nadir, Erdem Karacop, Ilke Celikkale, Mahmut Uluganyan, Razaman Ozdemir, Omer Goktekin
BACKGROUND: Although transcatheter aortic valve implantation (TAVI) can successfully correct aortic narrowing, pre-existing pathophysiological alterations in the left ventricle are still a concern in terms of long-term mortality. This study aimed to examine the predictive role of fQRS morphology on long-term prognosis in patients undergoing TAVI due to severe aortic stenosis. METHODS: A total of 117 patients undergoing TAVI due to severe aortic stenosis were included in this retrospective cohort study...
November 2018: Journal of Electrocardiology
Tetsuya Watanabe, Koichi Inoue, Kazunori Kashiwase, Takanao Mine, Keiji Hirooka, Ryu Shutta, Hiroya Mizuno, Yuji Okuyama, Yasushi Sakata, Shinsuke Nanto
BACKGROUND: Atrial fibrillation (AF) and ventricular arrhythmias (VAs) are associated with increased morbidity and mortality. However, data are lacking concerning the association of AF and VAs. This study aimed to clarify the association between AF and VAs and to investigate the effect of amiodarone on the incidence of VAs in patients with implantable cardioverter defibrillators (ICDs). METHODS AND RESULTS: We enrolled 612 patients who had ICDs or who underwent cardiac resynchronization therapy with a defibrillator (CRT-D) and classified them into two groups (sinus rhythm [SR] group, n = 427; AF group, n = 185) according to their basal rhythm at enrollment...
November 2018: Journal of Electrocardiology
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