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https://www.readbyqxmd.com/read/30091966/naloxone-administration-frequency-during-emergency-medical-service-events-united-states-2012-2016
#1
Rebecca E Cash, Jeremiah Kinsman, Remle P Crowe, Madison K Rivard, Mark Faul, Ashish R Panchal
As the opioid epidemic in the United States has continued since the early 2000s (1,2), most descriptions have focused on misuse and deaths. Increased cooperation with state and local partners has enabled more rapid and comprehensive surveillance of nonfatal opioid overdoses (3).* Naloxone administrations obtained from emergency medical services (EMS) patient care records have served as a useful proxy for overdose surveillance in individual communities and might be a previously unused data source to describe the opioid epidemic, including fatal and nonfatal events, on a national level (4-6)...
August 10, 2018: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/30073552/an-interprovincial-comparison-of-unintentional-childhood-injury-rates-in-canada-for-the-period-2006-2012
#2
Liraz Fridman, Jessica Fraser-Thomas, Ian Pike, Alison K Macpherson
OBJECTIVES: To perform an interprovincial comparison of unintentional population-based injury hospitalization and death rates for Canadian children ages 0-19 years and compare trends between 2006 and 2012. METHODS: Annual population-based hospitalization rates per 100,000 from unintentional injuries were calculated for children/youth (< 19 years) using data from the Discharge Abstract Database between 2006 and 2012. Annual mortality rates were analyzed using provincial coronial data...
August 2, 2018: Canadian Journal of Public Health. Revue Canadienne de Santé Publique
https://www.readbyqxmd.com/read/30055996/the-burden-of-disease-in-greece-health-loss-risk-factors-and-health-financing-2000-16-an-analysis-of-the-global-burden-of-disease-study-2016
#3
(no author information available yet)
BACKGROUND: Following the economic crisis in Greece in 2010, the country's ongoing austerity measures include a substantial contraction of health-care expenditure, with reports of subsequent negative health consequences. A comprehensive evaluation of mortality and morbidity is required to understand the current challenges of public health in Greece. METHODS: We used the results of the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2016 to describe the patterns of death and disability among those living in Greece from 2000 to 2010 (pre-austerity) and 2010 to 2016 (post-austerity), and compared trends in health outcomes and health expenditure to those in Cyprus and western Europe...
August 2018: Lancet. Public Health
https://www.readbyqxmd.com/read/30055353/early-fluid-overload-is-associated-with-an-increased-risk-of-non-relapse-mortality-after-ex-vivo-cd34-selected-allogeneic-hematopoietic-cell-transplantation
#4
Carlos Rondon-Clavo, Michael Scordo, Patrick Hilden, Gunjan L Shah, Christina Cho, Molly A Maloy, Esperanza B Papadopoulos, Ann A Jakubowski, Richard J O'Reilly, Boglarka Gyurkocza, Hugo Castro-Malaspina, Roni Tamari, Brian C Shaffer, Miguel-Angel Perales, Edgar A Jaimes, Sergio A Giralt
In a recently published and validated definition of fluid overload (FO), grade ≥ 2 FO was significantly associated with an increased risk of non-relapse mortality (NRM) after unmodified and haploidentical allogeneic hematopoietic cell transplantation (allo-HCT) using calcineurin inhibitor-based (CNI) graft-versus-host disease (GVHD) prophylaxis. We evaluated the effect of FO on outcomes in 169 patients undergoing myeloablative-conditioned ex-vivo CD34+ selected allo-HCT using the same grading scale. Thirty patients (17...
July 25, 2018: Biology of Blood and Marrow Transplantation
https://www.readbyqxmd.com/read/30053561/impact-of-perioperative-neurological-deficits-on-clinical-outcomes-following-posterior-cervical-fusion
#5
Sanjana Dayananda, Amol Mehta, Nitin Agarwal, Enyinna L Nwachuku, David K Hamilton, Parthasarathy D Thirumala
INTRODUCTION: In the United States, the number of posterior cervical fusions has increased substantially. Perioperative neurological complications associated with this procedure, such as spinal cord and peripheral nerve injuries, can have significant effects on patient health. As such, we examined the impact of perioperative neurological deficits on mortality in patients undergoing posterior cervical fusion. The secondary aim was to understand the risk factors for perioperative neurological complications...
July 24, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/30050667/a-burden-assessment-of-occupational-exposures-in-iran-1990-2010-findings-from-the-global-burden-of-disease-study-2010
#6
Sharareh R NiakanKalhori, Ali Behzadi, Hamidreza Maharlou, Shadi Rahimzadeh, Alireza Khajavi, Gholamreza Pouryaghoub, Ramin Mehrdad, Omid Aminian, Alireza Jeddian, Shohreh Naderimagham
Background: The present study describes the burden of occupational diseases in Iran based on the results of the Global Burden of Disease study conducted in 2010 (GBD 2010). This study aimed to determine the burden of occupational diseases in Iran based on the results of GBD 2010. It is a cross-sectional study. Methods: Disability-adjusted life years (DALYs) of occupational diseases were calculated based on the prevalence rates obtained through model estimation, as well as GBD 2010 disability weights and mortality rates obtained from different data registry systems of Iran...
2018: International Journal of Preventive Medicine
https://www.readbyqxmd.com/read/30043966/population-and-mortality-profile-in-the-islamic-republic-of-iran-2006-2035
#7
Saeide Aghamohamadi, Kamran Hajinabi, Katayoun Jahangiri, Iravan Masoudi Asl, Reza Dehnavieh
Background: The Islamic Republic of Iran has encountered demographic and epidemiological changes as a result of the transformation of health measures. Aims: This study aimed to calculate the population and mortality in the Islamic Republic of Iran during the years 2006 to 2035. Methods: We carried out a cross-sectional analytical-descriptive account. We calculated the age and sex structure of the Iranian population using census data as well as mathematical methods...
July 17, 2018: Eastern Mediterranean Health Journal, la Revue de Santé de la Méditerranée Orientale
https://www.readbyqxmd.com/read/30043954/advances-in-mexico-in-the-middle-of-the-decade-of-action-for-road-safety-2011-2020
#8
Martha Híjar, Ricardo Pérez-Núñez, Aarón Salinas-Rodríguez
OBJECTIVE: To analyze the progress towards the accomplishment of the expected goal in the middle of the Decade of Action for Road Safety 2011-2020 in Mexico and its states. METHODS: This is a secondary analysis of road traffic deaths in Mexico between 1999 and 2015. We projected the trend for the period 2011-2020 using a time series analysis (autoregressive integrated moving average models). We used the value of the Aikaike Information Criterion to determine the best model for the national level and its 32 states...
July 23, 2018: Revista de Saúde Pública
https://www.readbyqxmd.com/read/30037695/the-burden-of-disease-in-spain-results-from-the-global-burden-of-disease-2016
#9
Joan B Soriano, David Rojas-Rueda, Jordi Alonso, Josep M Antó, Pere-Joan Cardona, Esteve Fernández, Alberto L Garcia-Basteiro, Fernando G Benavides, Scott D Glenn, Varsha Krish, Jeffrey V Lazarus, José Martínez-Raga, Maria F Masana, Mark J Nieuwenhuijsen, Alberto Ortiz, Maria Dolores Sánchez-Niño, Antoni Serrano-Blanco, Miguel Tortajada-Girbés, Stefanos Tyrovolas, Josep Maria Haro, Mohsen Naghavi, Christopher J L Murray
BACKGROUND AND OBJECTIVES: The global burden of disease (GBD) project measures the health of populations worldwide on an annual basis, and results are available by country. We used the estimates of the GBD to summarise the state of health in Spain in 2016 and report trends in mortality and morbidity from 1990 to 2016. MATERIAL AND METHODS: GBD 2016 estimated disease burden due to 333 diseases and injuries, and 84 risk factors. The GBD list of causes is hierarchical and includes 3 top level categories, namely: 1) communicable, maternal, neonatal, and nutritional diseases; 2) non-communicable diseases (NCDs), and 3) injuries...
July 20, 2018: Medicina Clínica
https://www.readbyqxmd.com/read/30036659/identification-of-differentially-expressed-proteins-in-rats-with-spinal-cord-injury-during-the-transitional-phase-using-an-itraq-based-quantitative-analysis
#10
Hengxing Zhou, Yi Kang, Zhongju Shi, Lu Lu, Xueying Li, Tianci Chu, Jun Liu, Lu Liu, Yongfu Lou, Chi Zhang, Guangzhi Ning, Shiqing Feng, Xiaohong Kong
BACKGROUND: Spinal cord injury (SCI) is a disease associated with high disability and mortality rates. The transitional phase from subacute phase to intermediate phase may play a major role in the process of secondary injury. Changes in protein expression levels have been shown to play key roles in many central nervous system (CNS) diseases. Nevertheless, the roles of proteins in the transitional phase of SCI are not clear. METHODS: We examined protein expression in a rat model 2 weeks after SCI and identified differentially expressed proteins (DEPs) using isobaric tagging for relative and absolute protein quantification (iTRAQ)...
July 20, 2018: Gene
https://www.readbyqxmd.com/read/30032307/firefighter-fatalities-crude-mortality-rates-and-risk-factors-for-line-of-duty-injury-and-death
#11
Steven A Kahn, Clint Leonard, Carlos Siordia
Background: The United States Fire Administration (USFA) provides high-quality data for firefighter deaths (FFDs), but until now this data has not been analyzed for temporal trends. This analysis explores FFDs between 1990-2016 to determine high risk groups for outreach and training. Methods: Mortality rates were calculated using USFA information compared against the total number of deaths per-year. Rates were compared between 1990-2009 (early period) and 2010-2016 (recent period)...
July 18, 2018: Journal of Burn Care & Research: Official Publication of the American Burn Association
https://www.readbyqxmd.com/read/30030878/incidence-and-severity-of-head-injury-hospitalisations-in-australian-children-over-a-ten-year-period
#12
Mia Bierbaum, Reidar P Lystad, Kate Curtis, Rebecca Mitchell
ISSUE ADDRESSED: Child head injuries can cause life-long disability and are a major cause of mortality globally. The incidence and impact of child head injuries in Australia is unknown. This study aims to quantify the incidence, characteristics and treatment cost, and to identify factors associated with the severity of hospitalisations of head injuries in Australian children. METHODS: Linked hospitalisation and mortality data were used to retrospectively examine hospitalisation trends for head injury in children aged ≤16 years and associated factors, in Australia, from 1 July 2002 to 30 June 2012...
July 20, 2018: Health Promotion Journal of Australia
https://www.readbyqxmd.com/read/30026816/impact-of-acute-diabetes-decompensation-on-outcomes-of-diabetic-patients-admitted-with-st-elevation-myocardial-infarction
#13
Mayada Issa, Fahad Alqahtani, Chalak Berzingi, Mohammad Al-Hajji, Tatiana Busu, Mohamad Alkhouli
Background: Acute hyperglycemia is associated with worse outcomes in diabetic patients admitted with ST-elevation myocardial infarction (STEMI). However, the impact of full-scale decompensated diabetes on STEMI outcomes has not been investigated. Methods: We utilized the national inpatient sample (2003-2014) to identify adult diabetic patients admitted with STEMI. We defined decompensated diabetes as the presence of diabetic ketoacidosis (DKA) or hyperglycemic hyperosmolar state (HHS)...
2018: Diabetology & Metabolic Syndrome
https://www.readbyqxmd.com/read/30024278/trends-in-utilization-of-upper-extremity-reconstructive-surgery-following-traumatic-brain-injury-and-stroke
#14
Bryan G Beutel, Bryan J Marascalchi, Eitan Melamed
BACKGROUND: Spasticity resulting from traumatic brain injury (TBI) or stroke can lead to debilitating sequelae, including deformities from joint subluxation and spasticity, causing a loss of functional independence. Despite the effectiveness of surgery to address these issues, it is unclear how often these procedures are performed. The objective of the study was to determine the rate of, and trends associated with, reconstructive upper extremity surgery in patients following TBI or stroke...
July 1, 2018: Hand: Official Journal of the American Association for Hand Surgery
https://www.readbyqxmd.com/read/30021122/future-trends-in-the-treatment-of-non-alcoholic-steatohepatitis
#15
REVIEW
Stefano Fiorucci, Michele Biagioli, Eleonora Distrutti
With an estimated prevalence of ≈25% in Western and Asian countries, non alcoholic fatty liver disease (NAFLD), caused by chronic excessive caloric intake, is the emerging as the most prevalent liver disorder worldwide. NAFLD exists in two clinical entities, non-alcoholic fatty liver disease (NAFL), a relative benign disease that carry on minimal risk of liver-related morbidity but significant risk of cardiovascular complications, and non-alcoholic steatohepatitis (NASH), a progressive liver disorder with a significant risk for development of liver-related morbidities and mortality...
August 2018: Pharmacological Research: the Official Journal of the Italian Pharmacological Society
https://www.readbyqxmd.com/read/30018022/effect-of-acute-restraint-stress-in-a-polytrauma-rat-model
#16
Françoise Arnaud, Georgina Pappas, Ye Chen, Eric Maudlin-Jeronimo, Richard McCarron
INTRODUCTION: A stressful environment may contribute to poor outcomes after TBI. The current study evaluates the impact of acute stress in a polytrauma rat model. METHODS: Rats were stressed by a 45-minute immobilization period before instrumentation under ketamine (t1). Polytrauma was produced by blast overpressure and controlled hemorrhage (t2). Rats were euthanized immediately after a 3 h simulated Medevac-transport time (t3) or after 72 h post-trauma (t4)...
July 6, 2018: Neuroscience Letters
https://www.readbyqxmd.com/read/30004929/insurance-status-biases-trauma-system-utilization-and-appropriate-interfacility-transfer-national-and-longitudinal-results-of-adult-pediatric-and-older-adult-patients
#17
Cheryl K Zogg, Kevin M Schuster, Adrian A Maung, Kimberly A Davis
OBJECTIVE: To identify the association between insurance status and the probability of emergency department admission versus transfer for patients with major injuries (Injury Severity Score >15) and other complex trauma likely to require higher-level trauma center (TC) care across the spectrum of TC care. BACKGROUND: Trauma systems were developed to facilitate direct transport and transfer of patients with major/complex traumatic injuries to designated TCs. Emerging literature suggests that uninsured patients are more likely to be transferred...
July 12, 2018: Annals of Surgery
https://www.readbyqxmd.com/read/30004363/a-retrospective-time-trend-study-of-firearm-and-non-firearm-homicide-in-cape-town-from-1994-to-2013
#18
R Matzopoulos, J Simonetti, M Prinsloo, I Neethling, P Groenewald, J Dempers, L J Martin, A Rowhani-Rahbar, J E Myers, M L Thompson
BACKGROUND: Gunshot injuries from interpersonal violence are a major cause of mortality. In South Africa (SA), the Firearms Control Act of 2000 sought to address firearm violence by removing illegally owned firearms from circulation, stricter regulation of legally owned firearms, and stricter licensing requirements. Over the last few years, varied implementation of the Act and police corruption have increased firearm availability. OBJECTIVES: To investigate whether changes in firearm availability in SA were associated with changes in firearm homicide rates...
February 27, 2018: South African Medical Journal, Suid-Afrikaanse Tydskrif Vir Geneeskunde
https://www.readbyqxmd.com/read/29997567/visual-working-memory-encoding-and-recognition-in-good-outcome-aneurysmal-subarachnoid-patients
#19
Leodante da Costa, Priyanka P Shah-Basak, Benjamin T Dunkley, Andrew D Robertson, Elizabeth W Pang
Objectives: Aneurysmal subarachnoid hemorrhage (aSAH) accounts for less than 5% of strokes but is associated with significant morbidity and mortality. Amongst survivors, neurocognitive complaints are common, often despite normal imaging. We used magnetoencephalography (MEG) to investigate neurophysiological function during a visual working memory task in aSAH survivors with good recovery and normal structural imaging. Methods: Patients with aSAH treated with coiling and exhibiting good outcome measured by Glasgow Outcome Scale (GOS) and without related parenchymal structural lesions in post-treatment MRI, were recruited and compared to age- and sex-matched controls...
2018: Frontiers in Neurology
https://www.readbyqxmd.com/read/29997027/high-energy-trauma-patients-with-pelvic-fractures-management-trends-in-ontario-canada
#20
Stephen M Mann, Daniel Banaszek, Katherine Lajkosz, Susan B Brogly, Shelby M Stanojev, Chris Evans, Davide D Bardana, Jeff Yach, Stephen Hall
INTRODUCTION: Although fractures of the pelvic ring account for only 2-3% of all fractures, they are present in approximately 7-20% of patients with high-energy polytrauma. High-energy pelvic fractures are life-threatening injuries, with mortality estimates ranging from 6 to 35%. The purpose of this study was to examine trends in the incidence, diagnosis, treatment, and mortality rates of high-energy pelvic fractures in Ontario, Canada over a 10-year period. METHODS: A cohort of 3915 patients who sustained a high-energy pelvic fracture in Ontario between 01 April 2005 and 31 March 2015 was identified using the Ontario Trauma Registry and administrative healthcare data linked by the Institute for Clinical Evaluative Science (ICES)...
July 6, 2018: Injury
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