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JOURNAL ARTICLE
Qian Li, Chunfeng Guan, Yi Zhao, Xiaoye Duan, Zhihui Yang, Jiehua Zhu
Zinc (Zn) is considered as one of the heavy metal pollutants in soil affecting agriculture. Salicylic acid (SA) is an important phytohormone that can mitigate effects against various abiotic stresses in plants, however, its exploration to improve Zn stress tolerance in alfalfa plants is still elusive. Thus, in the present study, exogenous SA treatment was conducted on alfalfa plants under Zn stress. The effects of exogenous SA on the physiological effects of alfalfa plants and the expression levels related genes were studied...
September 25, 2023: Ecotoxicology and Environmental Safety
#22
Hongmei Zeng, Maomao Cao, Changfa Xia, Dongmei Wang, Kun Chen, Zheng Zhu, Ruiying Fu, Shaokai Zhang, Jinyi Zhou, Huadong Wang, Xianyun Qi, Shuguang Dai, Yong Chen, Zhong Sun, Hao Ding, Qingwen Li, Hui Zhao, Xuehong Zhang, Jakub Morze, John S Ji, Feng Sun, Xueqin Yu, Chunfeng Qu, Wanqing Chen
No abstract text is available yet for this article.
September 11, 2023: Nature Cancer
#23
JOURNAL ARTICLE
Miaomiao Zhao, Chunfeng Song, Fan Zhang, Xiaoyu Jia, Degang Ma
Global soil cadmium (Cd(II)) contamination threatens the soil environment, food safety, and human health. Conventional electrokinetic remediation (EKR) and enhancement methods usually operate in strong electric fields, leading to strong side reactions and uneven removal. In this work, to remove Cd(II) from soil effectively in a low-voltage electric field, a new-style electrokinetic-adsorption remediation using double-group electrodes coupled with chitosan-activated carbon composite membranes (DE-EKR-CAC) was developed...
September 7, 2023: Science of the Total Environment
#24
MULTICENTER STUDY
Hongmei Zeng, Maomao Cao, Changfa Xia, Dongmei Wang, Kun Chen, Zheng Zhu, Ruiying Fu, Shaokai Zhang, Jinyi Zhou, Huadong Wang, Xianyun Qi, Shuguang Dai, Yong Chen, Zhong Sun, Hao Ding, Qingwen Li, Hui Zhao, Xuehong Zhang, Jakub Morze, John S Ji, Feng Sun, Xueqin Yu, Chunfeng Qu, Wanqing Chen
Current guidelines recommend hepatocellular carcinoma (HCC) surveillance for at-risk individuals, including individuals with hepatitis B virus infection. However, the performance and survival benefits of annual screening have not been evaluated through multicenter prospective studies in a Chinese population. Between 2017 and 2021, we included 14,426 participants with hepatitis B surface antigen seropositivity in an annual HCC screening study in China using a multicenter prospective design with ultrasonography and serum alpha-fetoprotein...
September 2023: Nature Cancer
#25
JOURNAL ARTICLE
Bingjie Zhao, Zine Cao, Yushan Xie, Yewen Shi, Yitong Zhang, Shiyu Liu, Xi Chen, Lina Ma, Xiaoxin Niu, Yonglong Su, Yani Feng, Chunfeng Lian, Xiaoyong Ren, Haiqin Liu
BACKGROUND: To investigate the relationship between tongue fat content and severity of obstructive sleep apnea (OSA) and its effects on the efficacy of uvulopalatopharyngoplasty (UPPP) in the Chinese group. METHOD: Fifty-two participants concluded to this study were diagnosed as OSA by performing polysomnography (PSG) then they were divided into moderate group and severe group according to apnea hypopnea index (AHI). All of them were also collected a series of data including age, BMI, height, weight, neck circumference, abdominal circumference, magnetic resonance imaging (MRI) of upper airway and the score of Epworth Sleepiness Scale (ESS) on the morning after they completed PSG...
August 27, 2023: BMC Surgery
#26
JOURNAL ARTICLE
Ruochan Zhang, Kun Chen, Caifeng Gong, Zhiyuan Wu, Chungui Xu, Xing-Ning Li, Fei Zhao, Dongmei Wang, Jianqiang Cai, Aiping Zhou, Chunfeng Qu
BACKGROUND: Variated anti-cancer therapies are combined with immune checkpoint blockades (ICBs) for improving ICB therapeutic efficacy. Occurrence of tissue damage is common that triggers multiple inflammatory cytokine generation. Gastrointestinal organs are the commonly affected. We investigated the impact of acute colitis on tumor infiltration of antigen-specific CD8+ cytotoxic T lymphocytes (CTLs) for controlling tumor growth and responding to antibody against PD-1 (anti-PD-1). METHODS: Several tumor cell lines were inoculated into syngeneic mice subcutaneously or intra-hepatically...
August 21, 2023: BMC Medicine
#27
JOURNAL ARTICLE
Shuang Liu, Jianxun Wu, Zhiming Xu, Linzhou Zhang, Suoqi Zhao
The viscosity of heavy oil hinders its cold production, posing a major challenge to its exploitation. The high viscosity of heavy oil can be attributed to the content of asphaltene. However, during the collection of heavy oil samples from various regions in China, we observed that heavy oils with high total acid number (TAN) but low asphaltene content also exhibit relatively high viscosity. Hence, the viscosity mechanism of high-acid crude oil, the influence of petroleum acid on heavy oil viscosity, should be investigated...
August 8, 2023: ACS Omega
#28
JOURNAL ARTICLE
Dianne Little, Peter C Amadio, Hani A Awad, Stephanie G Cone, Nathaniel A Dyment, Matthew B Fisher, Alice H Huang, Drew W Koch, Andrew F Kuntz, Rashad Madi, Kirk McGilvray, Lauren V Schnabel, Snehal S Shetye, Stavros Thomopoulos, Chunfeng Zhao, Louis J Soslowsky
Several tendon and ligament animal models were presented at the 2022 Orthopaedic Research Society Tendon Section Conference held at the University of Pennsylvania, May 5 to 7, 2022. A key objective of the breakout sessions at this meeting was to develop guidelines for the field, including for preclinical tendon and ligament animal models. This review summarizes the perspectives of experts for eight surgical small and large animal models of rotator cuff tear, flexor tendon transection, anterior cruciate ligament tear, and Achilles tendon injury using the framework: "Why, Who, What, Where, When, and How" (5W1H)...
August 12, 2023: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
#29
JOURNAL ARTICLE
Lorenzo Mazzucchelli, Aida Kaivan Sarcon, Chieh-Ting Tony Huang, Jialun Li, Charlotte E Berry, Matthew Thomas Houdek, Atta Behfar, Chunfeng Zhao, Steven L Moran
Large skeletal muscle defects due to trauma or following tumor extirpation can result in substantial functional impairment. Purified exosomes are now available clinically and have been used for wound healing. The objective of this study was to evaluate the regenerative capacity of commercially available exosomes on an animal model of volumetric muscle loss (VML) and potential translation to human muscle injury. An established VML rat model was used. In the in-vitro experiment, rat myoblasts were isolated and co-cultured with 5% purified exosome product (PEP) to validate uptake...
August 3, 2023: Tissue Engineering. Part A
#30
JOURNAL ARTICLE
Feng He, Xueying Jin, Chunfeng Wang, Jingtao Hu, Shuai Su, Lei Zhao, Tingting Geng, Yuan Zhao, Li Pan, Nan Bao, Hui Sun
At present, most studies have shown that probiotics have a positive regulatory effect on the nutritional metabolism of the body, but the mechanism is still unclear. Here, 48 piglets were divided into four groups. The control group was not fed probiotics, the Lac group was fed L. Rhamnosus GG ATCC53103, the Rha group was fed L. Plantarum JL01, and the mix group was fed two types of probiotics. Nitrogen metabolism and mRNA levels of mTOR and S6K in skeletal muscle were observed in each group. Then, metagenome and non-targeted metabonomics were used to observe the changes of intestinal microorganisms and plasma metabolites in portal channels after probiotics feeding...
2023: Frontiers in Microbiology
#31
JOURNAL ARTICLE
Chun Bi, Andrew R Thoreson, Chunfeng Zhao
Allogenic tendons grafts sourced from intrasynovial tendons are often used for tendon reconstruction. Processing is achieved through repetitive freeze-thaw cycles followed by lyophilization. Soaking the lyophilized tendon in saline (0.9%) for 24 h is the standard practice for rehydration. However, data supporting saline rehydration over the use of other hydrating solutions are scant. The purpose of the current study was to compare the effects of different rehydration solutions on biomechanical properties of lyophilized tendon allograft...
May 25, 2023: Bioengineering
#32
JOURNAL ARTICLE
Shuai Zhao, Chengtuo Niu, Yiheng Wang, Youlong Zan, Feiyun Zheng, Chunfeng Liu, Jinjing Wang, Qi Li
This study aimed to elaborate the assembly processes and metabolic regulation of the microbial community under the conditions of environmental factors and artificial intervention using broad bean paste (BBP) fermentation as a tractable research object. Spatial heterogenicity of amino acid nitrogen, titratable acidity, and volatile metabolites were observed between upper and lower layers after fermentation for 2 weeks. Amino nitrogen contents in the upper fermented mash reached 0.86, 0.93, and 1.06 g/100 g at 2, 4, and 6 weeks, respectively, which were significantly higher than those of mash located at the lower layer (0...
July 26, 2023: Applied and Environmental Microbiology
#33
JOURNAL ARTICLE
Qian Liu, Jun Qi, Weihong Zhu, Andrew R Thoreson, Kai-Nan An, Scott P Steinmann, Chunfeng Zhao
The objective of this study was to examine the effect of pulling angle on time-zero mechanical properties of intact infraspinatus tendon or infraspinatus tendon repaired with the modified Mason-Allen technique in a canine model in vitro. Thirty-six canine shoulder samples were used. Twenty intact samples were randomly allocated into functional pull (135°) and anatomic pull (70°) groups ( n = 10 per group). The remaining sixteen infraspinatus tendons were transected from the insertion and repaired using the modified Mason-Allen technique before being randomly allocated into functional pull or anatomic pull groups ( n = 8 per group)...
May 17, 2023: Bioengineering
#34
JOURNAL ARTICLE
Hongjie Hu, Yuxiang Ma, Xiaoxiang Gao, Dawei Song, Mohan Li, Hao Huang, Xuejun Qian, Ray Wu, Keren Shi, Hong Ding, Muyang Lin, Xiangjun Chen, Wenbo Zhao, Baiyan Qi, Sai Zhou, Ruimin Chen, Yue Gu, Yimu Chen, Yusheng Lei, Chonghe Wang, Chunfeng Wang, Yitian Tong, Haotian Cui, Abdulhameed Abdal, Yangzhi Zhu, Xinyu Tian, Zhaoxin Chen, Chengchangfeng Lu, Xinyi Yang, Jing Mu, Zhiyuan Lou, Mohammad Eghtedari, Qifa Zhou, Assad Oberai, Sheng Xu
Serial assessment of the biomechanical properties of tissues can be used to aid the early detection and management of pathophysiological conditions, to track the evolution of lesions and to evaluate the progress of rehabilitation. However, current methods are invasive, can be used only for short-term measurements, or have insufficient penetration depth or spatial resolution. Here we describe a stretchable ultrasonic array for performing serial non-invasive elastographic measurements of tissues up to 4 cm beneath the skin at a spatial resolution of 0...
May 1, 2023: Nature Biomedical Engineering
#35
JOURNAL ARTICLE
Ramona L Reisdorf, Haoyu Liu, Chun Bi, Alyssa M Vrieze, Steven L Moran, Peter C Amadio, Chunfeng Zhao
BACKGROUND: Flexor digitorum profundus (FDP) tendon injury is common in hand trauma, and flexor tendon reconstruction is one of the most challenge procedures in hand surgery due to severe adhesion that exceed 25% and hinders hand function. Surface property of graft from extrasynovial tendons is inferior to the native intrasynovial FDP tendons, which has been reported as one of the major causations. Improve surface gliding ability of extrasynovial graft is needed. Thus, this study was to use carbodiimide derivatized synovial fluid and gelatin (cd-SF-gel) to modify the graft surface thus improving functional outcomes using a dog in-vivo model...
March 14, 2023: Plastic and Reconstructive Surgery
#36
JOURNAL ARTICLE
Yicun Wang, Guidong Shi, Tony C T Huang, Jialun Li, Zeling Long, Ramona Reisdorf, Alexander Y Shin, Peter Amadio, Atta Behfar, Chunfeng Zhao, Steven L Moran
BACKGROUND: Nerve injuries can result in detrimental functional outcomes. Currently, autologous nerve graft offers the best outcome for segmental peripheral nerve injury. Allografts are alternatives, but do not have comparable results. This study evaluated if plasma-derived exosome can improve nerve regeneration and functional recovery when combined with decellularized nerve allografts. METHODS: The effect of exosomes on Schwann cell proliferation and migration were evaluated...
March 14, 2023: Plastic and Reconstructive Surgery
#37
JOURNAL ARTICLE
Yajie Zhu, Feng Liu, Yulong Bai, Zebin Zhao, Chunfeng Ma, Adan Wu, Lijin Ning, Xiaowei Nie
The ability to accurately forecast the spread of coronavirus disease 2019 (COVID-19) is of great importance to the resumption of societal normality. Existing methods of epidemic forecasting often ignore the comprehensive analysis of multiple epidemic prevention measures. This paper aims to analyze various epidemic prevention measures through a compound framework. Here, a susceptible-vaccinated-infected-recovered-deceased (SVIRD) model is constructed to consider the effects of population mobility among origin and destination, vaccination, and positive retest populations...
March 2023: Heliyon
#38
JOURNAL ARTICLE
Mingyang Cheng, Makoye Mhozya Kanyema, Yu Sun, Wenhui Zhao, Yiyuan Lu, Junhong Wang, Xiaoxu Li, Chunwei Shi, Jianzhong Wang, Nan Wang, Wentao Yang, Yanlong Jiang, Haibin Huang, Guilian Yang, Yan Zeng, Chunfeng Wang, Xin Cao
African swine fever (ASF) is a devastating infectious disease of pigs caused by the African swine fever virus (ASFV), which poses a great danger to the global pig industry. Many viral proteins can suppress with interferon signaling to evade the host's innate immune responses. Therefore, the development of an effective vaccine against ASFV has been dampened. Recent studies have suggested that the L83L gene may be integrated into the host genome, weakening the host immune system, but the underlying mechanism is unknown...
February 28, 2023: Journal of Virology
#39
JOURNAL ARTICLE
Hongxu Pan, Zhenhua Liu, Jinghong Ma, Yuanyuan Li, Yuwen Zhao, Xiaoxia Zhou, Yaqin Xiang, Yige Wang, Xun Zhou, Runcheng He, Yali Xie, Qiao Zhou, Kai Yuan, Qian Xu, Qiying Sun, Junling Wang, Xinxiang Yan, Hainan Zhang, Chunyu Wang, Lifang Lei, Weiguo Liu, Xuejing Wang, Xuebing Ding, Tao Wang, Zheng Xue, Zhentao Zhang, Ling Chen, Qing Wang, Yonghong Liu, Jiayu Tang, Xuewei Zhang, Shifang Peng, Chaodong Wang, Jianqing Ding, Chunfeng Liu, Lijuan Wang, Haibo Chen, Lu Shen, Hong Jiang, Xinyin Wu, Hongzhuan Tan, Dan Luo, Shuiyuan Xiao, Xiang Chen, Jieqiong Tan, Zhengmao Hu, Chao Chen, Kun Xia, Zhuohua Zhang, Jia Nee Foo, Cornelis Blauwendraat, Mike A Nalls, Andrew B Singleton, Jun Liu, Piu Chan, Houfeng Zheng, Jinchen Li, Jifeng Guo, Jian Yang, Beisha Tang
Genome-wide association studies (GWASs) have identified numerous susceptibility loci for Parkinson's disease (PD), but its genetic architecture remains underexplored in populations of non-European ancestry. To identify genetic variants associated with PD in the Chinese population, we performed a GWAS using whole-genome sequencing (WGS) in 1,972 cases and 2,478 controls, and a replication study in a total of 8209 cases and 9454 controls. We identified one new risk variant rs61204179 (Pcombined = 1...
February 9, 2023: NPJ Parkinson's Disease
#40
JOURNAL ARTICLE
Jingyi Chen, Yilin Zhao, Haozhou Yang, Tianyu Zhang, Lei Fan, Chunfeng Li, Lei Wang
The electrochemical oxygen reduction reaction (ORR) has been recognized as a promising alternative for the sustainable production of H2 O2 . Here, we report a facile and effective strategy to promote ORR selectivity towards the 2e- product H2 O2 via electric double layer engineering. Specifically, in a model system using immobilized cobalt phthalocyanine as the electrocatalyst, H2 O2 selectivity has been improved from below 60% to over 93%, and the intrinsic activity for H2 O2 formation has been enhanced by more than 3 times upon the introduction of a cationic surfactant ( i...
February 23, 2023: Nanoscale
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