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"cardiopulmonary exercise testing"

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https://www.readbyqxmd.com/read/28329065/right-ventricular-outflow-tract-systolic-function-correlates-with-exercise-capacity-in-patients-with-severe-right-ventricle-dilatation-after-repair-of-tetralogy-of-fallot
#1
Shuhua Luo, Jianhua Li, Dan Yang, Yaxin Zhou, Qi An, Yucheng Chen
OBJECTIVES: The relationship between exercise capacity and right ventricular (RV) components function in repaired tetralogy of Fallot patients with severely dilated right ventricles is poorly understood. The aim of this study was to characterize the exercise capacity and its relationship to RV global and components function in repaired tetralogy of Fallot patients with RV end-diastolic volume index  >150 ml/m 2 , a currently accepted threshold for pulmonary valve replacement. METHODS: The medical records and results of cardiac magnetic resonance imaging and cardiopulmonary exercise testing of 25 consecutive eligible patients were reviewed...
February 16, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/28326310/cardiopulmonary-response-during-whole-body-vibration-training-in-patients-with-severe-copd
#2
Rainer Gloeckl, Petra Richter, Sandra Winterkamp, Michael Pfeifer, Christoph Nell, Jeffrey W Christle, Klaus Kenn
Several studies in patients with chronic obstructive pulmonary disease (COPD) have shown that whole-body vibration training (WBVT) has beneficial effects on exercise capacity. However, the acute cardiopulmonary demand during WBVT remains unknown and was therefore investigated in this study. Ten patients with severe COPD (forced expiratory volume in 1 s: 38±8% predicted) were examined on two consecutive days. On day one, symptom-limited cardiopulmonary exercise testing was performed on a cycle ergometer. The next day, six bouts of repeated squat exercises were performed in random order for one, two or three minutes either with or without WBVT while metabolic demands were simultaneously measured...
January 2017: ERJ Open Research
https://www.readbyqxmd.com/read/28325109/feasibility-and-effects-of-a-combined-adjuvant-high-intensity-interval-strength-training-in-breast-cancer-patients-a-single-center-pilot-study
#3
Sebastian Viktor Waldemar Schulz, Roman Laszlo, Stephanie Otto, Dmytro Prokopchuk, Uwe Schumann, Florian Ebner, Jens Huober, Jürgen Michael Steinacker
PURPOSE: To evaluate feasibility of an exercise intervention consisting of high-intensity interval endurance and strength training in breast cancer patients. METHODS: Twenty-six women with nonmetastatic breast cancer were consecutively assigned to the exercise intervention- (n= 15, mean age 51.9 ± 9.8 years) and the control group (n = 11, mean age 56.9 ± 7.0 years). Cardiopulmonary exercise testing that included lactate sampling, one-repetition maximum tests and a HADS-D questionnaire were used to monitor patients both before and after a supervised six weeks period of either combined high-intensity interval endurance and strength training (intervention group, twice a week) or leisure training (control group)...
March 21, 2017: Disability and Rehabilitation
https://www.readbyqxmd.com/read/28322759/validation-and-refinement-of-prediction-models-to-estimate-exercise-capacity-in-cancer-survivors-using-the-steep-ramp-test
#4
Martijn M Stuiver, Caroline S Kampshoff, Saskia Persoon, Wim Groen, Willem van Mechelen, Mai Jm Chinapaw, Johannes Brug, Frans Nollet, Marie-José Kersten, Goof Schep, Laurien M Buffart
OBJECTIVE: To further test the validity and clinical usefulness of the Steep Ramp Test (SRT) for estimating exercise tolerance in cancer survivors, by external validation and extension of previously published prediction models for VO2peak and Wpeak. DESIGN: Cross-sectional study. SETTING: Multicenter. PARTICIPANTS: Cardiopulmonary exercise tests (CPET) and SRT data from cancer survivors (n=283) in two randomized exercise trials...
March 18, 2017: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/28322688/correction-cardiopulmonary-exercise-testing
#5
Kenneth Leclerc
In the article, "Cardiopulmonary exercise testing: A contemporary and versatile clinical tool" (Leclerc K, Cleve Clin J Med 2017; 84:161-168), an error occurred in Table 1. Heart rate reserve was defined as maximum heart rate minus resting heart rate. It should be defined as (maximum heart rate minus resting heart rate) divided by (predicted maximum heart rate minus resting heart rate).
March 2017: Cleveland Clinic Journal of Medicine
https://www.readbyqxmd.com/read/28320577/pre-operative-functional-cardiovascular-reserve-is-associated-with-acute-kidney-injury-after-intervention
#6
A Saratzis, J Shakespeare, O Jones, M J Bown, A Mahmood, C H E Imray
BACKGROUND: Acute kidney injury (AKI) is a common complication after endovascular intervention, associated with poor short and long-term outcomes. However, the mechanisms underlying AKI development remain poorly understood. The impact of pre-existing cardiovascular disease and low cardiovascular reserve (CVR) in AKI is unclear; it remains unknown whether AKI is primarily related to pre-existing comorbidity or to procedural parameters. The association between CVR and AKI after EVAR was therefore assessed...
March 17, 2017: European Journal of Vascular and Endovascular Surgery
https://www.readbyqxmd.com/read/28318852/cardiorespiratory-optimal-point-during-exercise-testing-as-a-predictor-of-all-cause-mortality
#7
Plínio S Ramos, Claudio Gil S Araújo
INTRODUCTION AND AIM: The cardiorespiratory optimal point (COP) is a novel index, calculated as the minimum oxygen ventilatory equivalent (VE/VO2) obtained during cardiopulmonary exercise testing (CPET). In this study we demonstrate the prognostic value of COP both independently and in combination with maximum oxygen consumption (VO2max) in community-dwelling adults. METHODS: Maximal cycle ergometer CPET was performed in 3331 adults (66% men) aged 40-85 years, healthy (18%) or with chronic disease (81%)...
March 17, 2017: Portuguese Journal of Cardiology: An Official Journal of the Portuguese Society of Cardiology
https://www.readbyqxmd.com/read/28315502/the-effect-of-left-ventricular-assist-device-therapy-in-patients-with-heart-failure-and-mixed-pulmonary-hypertension
#8
Hoong S Lim, Neil Howell, Aaron Ranasinghe
BACKGROUND: Diastolic pressure gradient (DPG) of ≥7 mmHg has been proposed to distinguish mixed pulmonary hypertension from isolated post-capillary pulmonary hypertension in heart failure (HF). We evaluated the changes in pulmonary hemodynamics with left ventricular assist devices (LVADs) in patients with DPG of ≥7 or <7 mmHg, and effects on peak oxygen uptake (VO2) in patients with advanced HF. METHODS: Pre- and post-LVAD implant pulmonary hemodynamics (including right atrial (RA) pressures, DPG, pulmonary vascular resistance (PVR), pulmonary capacitance (PCap) and cardiac output), echocardiography, cardiopulmonary exercise test were measured in 38 consecutive patients...
March 16, 2017: International Journal of Artificial Organs
https://www.readbyqxmd.com/read/28298387/diagnosis-of-chronic-thromboembolic-pulmonary-hypertension
#9
REVIEW
Deepa Gopalan, Marion Delcroix, Matthias Held
Chronic thromboembolic pulmonary hypertension (CTEPH) is the only potentially curable form of pulmonary hypertension. Rapid and accurate diagnosis is pivotal for successful treatment. Clinical signs and symptoms can be nonspecific and risk factors such as history of venous thromboembolism may not always be present. Echocardiography is the recommended first diagnostic step. Cardiopulmonary exercise testing is a complementary tool that can help to identify patients with milder abnormalities and chronic thromboembolic disease, triggering the need for further investigation...
January 2017: European Respiratory Review: An Official Journal of the European Respiratory Society
https://www.readbyqxmd.com/read/28286137/impact-of-cardiorespiratory-fitness-on-all-cause-and-disease-specific-mortality-advances-since-2009
#10
REVIEW
Matthew P Harber, Leonard A Kaminsky, Ross Arena, Steven N Blair, Barry A Franklin, Jonathan Myers, Robert Ross
Cardiorespiratory fitness (CRF) has been one of the most widely examined physiological variables, particularly as it relates to functional capacity and human performance. Over the past three decades, CRF has emerged as a strong, independent predictor of all-cause and disease-specific mortality. The evidence supporting the prognostic use of CRF is so powerful that the American Heart Association recently advocated for the routine assessment of CRF as a clinical vital sign. Interestingly, the continuity of evidence of the inverse relationship between CRF and mortality over the past decade exists despite a wide variation of methods used to assess CRF in these studies, ranging from the gold-standard method of directly measured maximal oxygen uptake (VO2max) during cardiopulmonary exercise testing to estimation from exercise tests and non-exercise prediction equations...
March 9, 2017: Progress in Cardiovascular Diseases
https://www.readbyqxmd.com/read/28284501/cardiopulmonary-exercise-test-in-adults-with-prior-fontan-operation-the-prognostic-value-of-serial-testing
#11
Alexander C Egbe, David J Driscoll, Arooj R Khan, Sameh S Said, Emmanuel Akintoye, Fernando M Berganza, Heidi M Connolly
BACKGROUND: The purpose of the study was to determine the role of cardiopulmonary exercise test (CPET) indices in predicting cardiovascular adverse events (CAEs) in patients with Fontan palliation. CAE was defined as death or cardiac surgery. METHODS: Retrospective review of adult Fontan patients who had treadmill CPET at Mayo Clinic, 1994-2013. Patients with loss of follow-up defined as ≥2years without clinical follow-up were excluded. The results of serial CPETs were reviewed, and patients with CPETs meeting the following criteria were selected for analysis: maximum effort on serial CPETs, minimum of 3-year interval between CPETs, and absence of CAE between CPETs...
February 28, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28283422/importance-of-compensatory-heart-rate-increase-during-myocardial-ischemia-to-preserve-appropriate-oxygen-kinetics
#12
Sadamitsu Yoshida, Hitoshi Adachi, Makoto Murata, Junichi Tomono, Shigeru Oshima, Masahiko Kurabayashi
BACKGROUND: Myocardial ischemia induces cardiac dysfunction, resulting in insufficient oxygen supply to peripheral tissues and mismatched energy production during exercise. To relieve the insufficient oxygen supply, heart rate (HR) response is augmented; however, beta-adrenergic receptor blockers (BB) restrict HR response. Although BB are essential drugs for angina pectoris, the effect of BB on exercise tolerance in patients with angina has not been studied. The aim of this study was to clarify the importance of HR augmentation to preserve exercise tolerance in patients with angina pectoris...
March 7, 2017: Journal of Cardiology
https://www.readbyqxmd.com/read/28283393/effect-of-metformin-on-exercise-capacity-in-metabolic-syndrome
#13
Abi Albon Paul, Steven Aibor Dkhar, Sadishkumar Kamalanathan, Molly Mary Thabah, Melvin George, Indumathi Chandrasekaran, Vikneswaran Gunaseelan, Sandhiya Selvarajan
OBJECTIVE: Metabolic syndrome is a constellation of risk factors with increased predilection towards occurrence of cardiovascular diseases. Currently physical exercise and management with metformin are the prevailing treatment modalities for metabolic syndrome. Patients with metabolic syndrome have been found to have reduced exercise capacity over a period of time. Likewise metformin has been shown to decrease exercise capacity among healthy volunteers. Hence this study aims to evaluate the effect of metformin on the exercise capacity of patients with metabolic syndrome...
March 6, 2017: Diabetes & Metabolic Syndrome
https://www.readbyqxmd.com/read/28283234/endothelin-inhibitors-lower-pulmonary-vascular-resistance-and-improve-functional-capacity-in-patients-with-fontan-circulation
#14
Gabriella Agnoletti, Simona Gala, Francesca Ferroni, Roberto Bordese, Lorenzo Appendini, Carlo Pace Napoleone, Laura Bergamasco
OBJECTIVES: To evaluate the effects of endothelin inhibitors (ERAs) on hemodynamic and functional parameters in patients post-Fontan procedure with high pulmonary vascular resistance (PVR). METHODS: Among our cohort of patients with Fontan circulation, 8 children, 8 adolescents, and 8 adults had PVR ≥2 WU*m(2). These patients were treated with ERAs (minors with bosentan, adults with macitentan) and reevaluated after 6 months. Pre- and posttreatment hemodynamic variables were assessed by cardiac catheterization...
February 10, 2017: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28275353/advances-in-the-evaluation-of-respiratory-pathophysiology-during-exercise-in-chronic-lung-diseases
#15
REVIEW
Denis E O'Donnell, Amany F Elbehairy, Danilo C Berton, Nicolle J Domnik, J Alberto Neder
Dyspnea and exercise limitation are among the most common symptoms experienced by patients with various chronic lung diseases and are linked to poor quality of life. Our understanding of the source and nature of perceived respiratory discomfort and exercise intolerance in chronic lung diseases has increased substantially in recent years. These new mechanistic insights are the primary focus of the current review. Cardiopulmonary exercise testing (CPET) provides a unique opportunity to objectively evaluate the ability of the respiratory system to respond to imposed incremental physiological stress...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28275174/physiological-and-clinical-relevance-of-exercise-ventilatory-efficiency-in-copd
#16
REVIEW
J Alberto Neder, Danilo C Berton, Flavio F Arbex, Maria Clara Alencar, Alcides Rocha, Priscila A Sperandio, Paolo Palange, Denis E O'Donnell
Exercise ventilation (V'E) relative to carbon dioxide output (V'CO2 ) is particularly relevant to patients limited by the respiratory system, e.g. those with chronic obstructive pulmonary disease (COPD). High V'E-V'CO2 (poor ventilatory efficiency) has been found to be a key physiological abnormality in symptomatic patients with largely preserved forced expiratory volume in 1 s (FEV1). Establishing an association between high V'E-V'CO2 and exertional dyspnoea in mild COPD provides evidence that exercise intolerance is not a mere consequence of detraining...
March 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/28274955/physical-activity-in-adults-with-congenital-heart-disease-and-associations-with-functional-outcomes
#17
Jan Müller, Tamara Amberger, Anika Berg, Daniel Goeder, Julia Remmele, Renate Oberhoffer, Peter Ewert, Alfred Hager
OBJECTIVE: Improved survival has yielded to growing importance of functional outcome measures in patients with congenital heart disease (CHD). This study applied the International Physical Activity Questionnaire (IPAQ) to assess self-reported physical activity (PA) in patients with CHD and their association with exercise capacity and health-related quality of life (HrQoL). PATIENTS AND METHODS: Prior to cardiopulmonary exercise testing (CPET), 786 consecutive patients (335 female, 31...
March 8, 2017: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/28262206/chronotropic-incompetence-and-its-relation-to-exercise-intolerance-in-chronic-obstructive-pulmonary-disease
#18
Hai-Jian Liu, Jian Guo, Qin-Hua Zhao, Lan Wang, Wen-Lan Yang, Jing He, Su-Gang Gong, Jin-Ming Liu
BACKGROUND: To study the relationship between chronotropic incompetence (CI) and disease severity and to assess the effect of CI on exercise capacity in patients with chronic obstructive pulmonary disease (COPD). MATERIALS AND METHODS: Arterial blood gas analysis, pulmonary function test and cardiopulmonary exercise testing were conducted in 60 patients with stable COPD and 45 healthy volunteers. CI was defined using the chronotropic response index (CRI = (peak heart rate-resting heart rate) / (220-age-resting heart rate)...
March 2017: American Journal of the Medical Sciences
https://www.readbyqxmd.com/read/28255103/percutaneous-coronary-intervention-of-coronary-chronic-total-occlusions-improves-peak-oxygen-uptake-during-cardiopulmonary-exercise-testing
#19
Shuaib M Abdullah, Jeffrey L Hastings, Suwetha Amsavelu, Fransisco Garcia-Morales, Fury Hendrix, Aris Karatasakis, Barbara A Danek, Judit Karacsonyi, Bavana V Rangan, Michele Roesle, Houman Khalili, Subhash Banerjee, Emmanouil S Brilakis
OBJECTIVES: Although coronary chronic total occlusions (CTOs) are treated with percutaneous coronary intervention (PCI) to improve symptoms, studies demonstrating symptom improvement have been mostly limited to questionnaire responses. The current study assessed for changes in peak oxygen uptake during cardiopulmonary exercise testing after CTO-PCI. METHODS: Patients with heart failure or angina symptoms referred for CTO-PCI were prospectively enrolled. The primary outcome of the study was improvement in peak oxygen uptake during cardiopulmonary exercise (CPX) testing 5 months after CTO-PCI...
March 2017: Journal of Invasive Cardiology
https://www.readbyqxmd.com/read/28251691/sinus-tachycardia-is-associated-with-impaired-exercise-tolerance-following-heart-transplantation
#20
Yael Peled-Potashnik, Sara Varnado, Brian D Lowes, Ronald Zolty, Elizabeth R Lyden, Michael J Moulton, John Y Um, Eugenia Raichlin
BACKGROUND: Sinus tachycardia often presents in heart transplantation (HTx) recipients, but data on its effect on exercise performance are limited. METHODS: Based on mean heart rate (HR) value 3 months after HTx, 181 patients transplanted from 2005 to 2016 at Nebraska Medical Center were divided into 2 groups: 1) HR<95 beats/min (bpm, n= 93) and 2) HR≥95 bpm (n=88). Cardiopulmonary exercise testing (CPET) was performed 1 year after HTx. RESULTS: Mean HR at 3 months post- HTx was 94 ±11 bpm and did not change significantly at 1 year post- HTx (96±11 bpm, p=0...
March 2, 2017: Clinical Transplantation
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