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https://www.readbyqxmd.com/read/28337491/meeting-report-unesco-merck-africa-research-summit-2015-accelerating-access-and-sustaining-innovation-from-africa-for-africa
#1
R W Omange, A O Ocholla, A O Kwallah, S N Kageha, J Mwangi, R K Cherutich, Odeny T A, T Nzomo, S Angwenyi, P Yonga, F Kariuki, M Kyalo, P C Mutai, F Nindo, E M Songok
BACKGROUND: The Ebola virus disease outbreak of 2014 was the largest, longest and most devastating in the history of the disease. It demonstrated the social and economic impact an emerging infectious disease can have in a globalized world. Health systems in affected countries were stretched to the point of near collapse, while social relations and traditional practices were negatively impacted. Heads of African research institutions, African government representatives, leaders of global pharmaceutical companies, global infectious disease experts and close to 100 young African researchers from 25 countries; Assembled in Geneva on 19 and 20th October 2015, for the inaugural UNESCO-Merck Africa Summit sponsored by the United Nations Educational, Science and Culture Organization and Merck KGA...
2017: African Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28335787/risk-factors-of-atherosclerotic-tissue-types-in-single-vessel-and-intermediate-coronary-lesions-a-cross-sectional-study
#2
Xianjin Wang, Qun Chen, Yu Xu, Yanqing Wang, Yang Yang, Ming Gu, Haihua Xu, Yanfang Zhao
BACKGROUND: Few data exist that correlate lesion-related risk factors such as conventional cardiovascular risks or lipoprotein-associated phospholipase A2 (Lp-PLA2) with tissue types within atherosclerotic plaques in patients with single-vessel and intermediate coronary lesions. METHODS: One hundred and ninety-two patients with single-vessel and intermediate coronary lesions were enrolled in a cross-sectional study and divided into two groups: stable angina pectoris (SAP) and acute coronary syndrome (ACS) groups...
March 23, 2017: Lipids in Health and Disease
https://www.readbyqxmd.com/read/28334584/delayed-workup-of-rectal-bleeding-in-adult-primary-care-examining-process-of-care-failures
#3
Saul N Weingart, Elena M Stoffel, Daniel C Chung, Thomas D Sequist, Ruth I Lederman, Stephen R Pelletier, Helen M Shields
BACKGROUND: Although delayed colorectal cancer diagnoses figure prominently in medical malpractice claims, little is known about the quality of primary care clinicians' workup of rectal bleeding. METHODS: In this study, 438 patients were identified using International Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9-CM) codes for rectal bleeding, hemorrhoids, and blood in the stool at 10 Boston adult primary care practices. Following nurse chart abstraction, physician reviewers assessed the overall quality of care and key care processes...
January 2017: Joint Commission Journal on Quality and Patient Safety
https://www.readbyqxmd.com/read/28332898/herpes-simplex-virus-1-and-cytomegalovirus-dnas-detection-in-the-inner-ear-of-implanted-patients-with-non-congenital-infection
#4
Walter Di Nardo, Roberta Anzivino, Paola Cattani, Rosaria Santangelo, Eugenio De Corso, Gaetano Paludetti
CONCLUSIONS: The detection of cytomegalovirus (CMV) and herpes simplex virus-1 (HSV-1) genome in perilymph of patients with negative serology or clinical history for congenital infections supports the hypothesis that Herpesviridae, even after acquired postnatal infections, could remain in latent phase in the spiral ganglion and damage the cochlea by a possible subsequent reactivation. Further studies are needed to identify the markers of such reactivation. OBJECTIVE: To identify the presence of certain viral species in the endolabyrinthic fluid of deaf patients with non-congenital infection...
March 23, 2017: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/28330539/-state-of-the-art-work-up-of-dementia-disorder
#5
Steen Gregers Hasselbalch
Early diagnosis of a dementia disorder is required for early support, treatment and information. A basic programme including history taking, somatic and neurological examination, blood screening and a structural scan will suffice in typical cases. For patients with uncertain or atypical symptoms or disease course, supplementary investigations are warranted, including biomarkers in cerebrospinal fluid, functional imaging and neuropsychological testing. Also, imaging of specific protein accumulations in Alzheimer's disease may serve to monitor disease progression and effects of interventions...
March 20, 2017: Ugeskrift for Laeger
https://www.readbyqxmd.com/read/28330492/the-prevalence-awareness-treatment-and-control-of-dyslipidemia-in-northeast-china-a-population-based-cross-sectional-survey
#6
Fu-Liang Zhang, Ying-Qi Xing, Yan-Hua Wu, Hao-Yuan Liu, Yun Luo, Ming-Shuo Sun, Zhen-Ni Guo, Yi Yang
BACKGROUND: Dyslipidemia is an important independent modifiable risk factor for cardiovascular disease. The aim of this study was to explore the current prevalence, awareness, treatment and control of dyslipidemia and its associated influence factors in northeast China. METHODS: In this population-based cross-sectional study, we adopted a multi-stage, stratified sampling method to obtain a representative sample of 4052 permanent residents aged 40 years and over from different urban and rural regions in Dehui City of Jilin Province...
March 23, 2017: Lipids in Health and Disease
https://www.readbyqxmd.com/read/28329648/hormonal-and-reproductive-factors-and-incidence-of-basal-cell-carcinoma-in-a-population-based-cohort
#7
Catherine M Olsen, Nirmala Pandeya, Bridie S Thompson, Jean Claude Dusingize, Padmini Subramaniam, Christina M Nagle, Adele C Green, Rachel E Neale, Penny M Webb, David C Whitman
Estrogens have photosensitizing properties, but few prospective studies have examined the relationship between hormonal and reproductive factors and incidence of basal cell carcinoma (BCC) in women. Previous findings have been inconsistent, particularly in relation to parity and use of oral contraceptives (OCs) and menopausal hormone therapy (MHT). Given the heterogeneity in the literature, we sought to examine the association between hormonal and reproductive factors and BCC risk in a cohort of women (n=23,879) enrolled in the QSkin Study in 2011...
September 15, 2016: Dermatology Online Journal
https://www.readbyqxmd.com/read/28329031/who-take-naps-self-reported-and-objectively-measured-napping-in-very-old-women
#8
Yue Leng, Katie Stone, Sonia Ancoli-Israel, Kenneth Covinsky, Kristine Yaffe
Background: Despite the widespread belief that napping is common among older adults, little is known about the correlates of napping. We examined the prevalence and correlates of self-reported and objectively measured napping among very old women. Methods: We studied 2,675 community-dwelling women (mean age 84.5 ± 3.7 years; range 79-96). Self-reported napping was defined as a report of regular napping for ≥1 hour per day. Individual objective naps were defined as ≥5 consecutive minutes of inactivity as measured by actigraphy and women were characterized as "objective nappers" if they had at least 60 minutes of naps per day...
February 18, 2017: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
https://www.readbyqxmd.com/read/28327574/from-older-to-younger-intergenerational-promotion-of-health-behaviours-in-portuguese-families-affected-by-familial-amyloid-polyneuropathy
#9
Carla Roma Oliveira, Alvaro Mendes, Liliana Sousa
The role of older generations in families with hereditary diseases has been recognised and associated to their function as guardians of the family's medical history. However, research is scarce in examining the roles that older generations play in terms of health promotion and risk management towards younger generations, which is particularly evident with incurable genetically inherited disorders such as familial amyloid polyneuropathy (FAP) ATTR Val30Met. This qualitative exploratory study examines the roles that older generations play towards younger generations, in terms of health promotion and risk management, in families with FAP...
March 22, 2017: European Journal of Human Genetics: EJHG
https://www.readbyqxmd.com/read/28324050/transgender-health-in-endocrinology-current-status-of-endocrinology-fellowship-programs-and-practicing-clinicians
#10
Caroline Davidge-Pitts, Todd B Nippoldt, Ann Danoff, Lauren Radziejewski, Neena Natt
Context: The transgender population continues to face challenges in accessing appropriate health care. Adequate training of endocrinologists in this area is a priority. Objectives: 1) Assess the status of transgender healthcare education in United States (US) endocrinology fellowship training programs, and 2) assess knowledge and practice of transgender health amongst practicing US endocrinologists. Design: Mayo Clinic and Endocrine Society developed and administered a web-based anonymous survey to 104 endocrinology fellowship program directors (PDs) and 6,992 US MD members of Endocrine Society...
January 10, 2017: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28323867/understanding-and-coping-with-extremism-in-an-online-collaborative-environment-a-data-driven-modeling
#11
Csilla Rudas, Olivér Surányi, Taha Yasseri, János Török
The Internet has provided us with great opportunities for large scale collaborative public good projects. Wikipedia is a predominant example of such projects where conflicts emerge and get resolved through bottom-up mechanisms leading to the emergence of the largest encyclopedia in human history. Disaccord arises whenever editors with different opinions try to produce an article reflecting a consensual view. The debates are mainly heated by editors with extreme views. Using a model of common value production, we show that the consensus can only be reached if groups with extreme views can actively take part in the discussion and if their views are also represented in the common outcome, at least temporarily...
2017: PloS One
https://www.readbyqxmd.com/read/28323502/head-injury-and-substance-use-in-young-adults
#12
Lisa A Kort-Butler
BACKGROUND: Prior studies suggest a link between head injuries and substance use but do not routinely capture mechanisms connecting the two. OBJECTIVES: The goal of the study was to explore whether past head injuries predicted current substance use among young adults, taking factors such as stress, self-esteem, temper, and risk-taking into consideration. METHODS: Data were drawn from a web-based survey conducted in 2014 and 2015 at a public university in the United States (n = 897)...
March 21, 2017: Substance Use & Misuse
https://www.readbyqxmd.com/read/28321081/metoclopramide-induced-serotonin-syndrome
#13
Taku Harada, Takanobu Hirosawa, Kouhei Morinaga, Taro Shimizu
A 40-year-old woman with bipolar disorder who was taking mirtazapine presented with mydriasis, abnormal diaphoresis, myoclonus and muscle rigidity after taking metocloplamide. Her medical history, which included the use of serotonergic agents, and the presence of symptoms including myoclonus and muscle rigidity were consistent with a diagnosis of serotonin syndrome (SS) according to the Hunter criteria. The symptoms diminished following three days of treatment with oral lorazepam and cyproheptadine and a reduced dose of mirtazapine...
2017: Internal Medicine
https://www.readbyqxmd.com/read/28320200/clinical-and-biological-features-of-interval-colorectal-cancer
#14
Yu Mi Lee, Kyu Chan Huh
Interval colorectal cancer (I-CRC) is defined as a CRC diagnosed within 60 months after a negative colonoscopy, taking into account that 5 years is the "mean sojourn time." It is important to prevent the development of interval cancer. The development of interval colon cancer is associated with female sex, old age, family history of CRC, comorbidities, diverticulosis, and the skill of the endoscopist. During carcinogenesis, sessile serrated adenomas/polyps (SSA/Ps) share many genomic and colonic site characteristics with I-CRCs...
March 21, 2017: Clinical Endoscopy
https://www.readbyqxmd.com/read/28319319/association-between-religious-practice-and-risk-of-depression-in-older-people-in-the-subacute-setting
#15
Alice Lac, Nicole Austin, Renata Lemke, Suma Poojary, Peter Hunter
OBJECTIVE: To identify the association between religious practice and risk of depression in older people admitted to a subacute hospital. METHODS: A cross-sectional survey was conducted with 100 patients aged ≥65 years with Mini-Mental State Examination (MMSE) scores ≥24 consecutively admitted to a subacute hospital. Religious practice was measured using the Duke University Religion Index and risk of depression using the 15-item Geriatric Depression Scale (GDS)...
March 20, 2017: Australasian Journal on Ageing
https://www.readbyqxmd.com/read/28318358/assessing-abnormal-uterine-bleeding-are-physicians-taking-a-meaningful-clinical-history
#16
Christina Lam, Britta Anderson, Vrishali Lopes, Jay Schulkin, Kristen Matteson
INTRODUCTION: Women with abnormal uterine bleeding (AUB) report significant reductions in quality of life (QOL), which can be attributed in many cases to the fear of embarrassing episodes of bleeding. We performed this study to determine whether or not during clinical encounters physicians addressed the impact of AUB on patient-reported QOL. MATERIALS AND METHODS: Between October 2008 and May 2009, we conducted a cross-sectional study of members of the American College of Obstetricians and Gynecologists...
March 20, 2017: Journal of Women's Health
https://www.readbyqxmd.com/read/28316204/-retrospect-of-chinese-herbs-taken-as-tea-drinking
#17
J N Zhu, X L Zhang, H Guo
Tea and wine are time-honored drinks in China. Along with coffee and cocoa, tea, as one of the non-alcoholic plant beverages, is prevailing the world. Tea and Chinese medicine has a very close relationship. Chinese herbs taken as tea forming the tea-like medicinal tea, can be taken frequently at anytime. The application of Chinese herbs taken as tea drinking begins from the Tang Dynasty, flourishes in the Song Dynasty and matures in the Qing Dynasty. The review of its history provides ample evidence of Chinese herbs taken as tea drinking in treating and preventing diseases, as well as providing the clues and references of developing new Chinese herbs taking as tea...
January 28, 2017: Zhonghua Yi Shi za Zhi, Chinese Journal of Medical History
https://www.readbyqxmd.com/read/28314756/predicting-occupational-asthma-and-rhinitis-in-bakery-workers-referred-for-clinical-evaluation
#18
Badri Sadat Jonaid, Jos Rooyackers, Erik Stigter, Lützen Portengen, Esmeralda Krop, Dick Heederik
BACKGROUND: Occupational allergic diseases are a major problem in some workplaces like in the baking industry. Diagnostic rules have been used in surveillance but not yet in the occupational respiratory clinic. OBJECTIVE: To develop diagnostic models predicting baker's asthma and rhinitis among bakery workers at high risk of sensitisation to bakery allergens referred to a specialised clinic. METHODS: As part of a medical surveillance programme, clinical evaluation was performed on 436 referred Dutch bakery workers at high risk for sensitisation to bakery allergens...
March 17, 2017: Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/28306346/risk-factors-for-central-serous-chorioretinopathy-multivariate-approach-in-a-case-control-study
#19
Irini Chatziralli, Stamatina A Kabanarou, Efstratios Parikakis, Alexandros Chatzirallis, Tina Xirou, Panagiotis Mitropoulos
PURPOSE: The purpose of this prospective study was to investigate the potential risk factors associated independently with central serous retinopathy (CSR) in a Greek population, using multivariate approach. MATERIALS AND METHODS: Participants in the study were 183 consecutive patients diagnosed with CSR and 183 controls, matched for age. All participants underwent complete ophthalmological examination and information regarding their sociodemographic, clinical, medical and ophthalmological history were recorded, so as to assess potential risk factors for CSR...
March 17, 2017: Current Eye Research
https://www.readbyqxmd.com/read/28300293/coronary-artery-calcification-is-common-on-nongated-chest-computed-tomography-imaging
#20
Revathi Balakrishnan, Brian Nguyen, Roy Raad, Robert Donnino, David P Naidich, Jill E Jacobs, Harmony R Reynolds
BACKGROUND: Coronary artery calcification as assessed by computed tomography (CT) is a validated predictor of cardiovascular risk, whether identified on a dedicated cardiac study or on a routine non-gated chest CT. The prevalence of incidentally detected coronary artery calcification on non-gated chest CT imaging and consistency of reporting have not been well characterized. HYPOTHESIS: Coronary calcification is present on chest CT in some patients not taking statin therapy and may be under-reported...
March 16, 2017: Clinical Cardiology
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