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atrial fibrillation recurrence risk factors

Chan Joo Lee, Tae-Hoon Kim, Sungha Park, Hui-Nam Pak
Background: Obstructive sleep apnea (OSA) is a well-known predictor of atrial fibrillation (AF). However, OSA usually accompanies other risk factors of AF. We tried to investigate whether OSA is related to AF recurrence after catheter ablation. Methods: A total of 378 patients (mean age 59.9 ± 10.7 years, 72.5$ male) who underwent catheter ablation of AF were enrolled and underwent overnight ambulatory polysomnography before the ablation procedure. These patients were examined once every 3 months at the outpatient clinic to determine AF recurrence...
July 2018: Pulse (Basel, Switzerland)
Ya Zhu Wang, Jinqi Fan, Bin Zhong, Qiang Xu
Apelin, the ligand for the APJ receptor, is involved in the pathogenesis of atrial fibrillation (AF). However, whether serum apelin can predict the recurrence of AF after pulmonary vein isolation (PVI) has not been determined.A prospective cohort study was performed in patients with AF (but without structural heart disease) who were undergoing first-time PVI. Serum apelin-12 was measured by enzyme-linked immunosorbent assay. Echocardiographic examination was performed at baseline, 3 months, and 6 months after PVI...
September 2018: Medicine (Baltimore)
Bibijana Rostohar Bijelić, Marta Petek, Mira Kadojić, Nikola Bijelić, Dragutin Kadojić
The aim of this study was to determine the distribution of risk factors according to age, gender, subtypes and recurrence of stroke in eastern Croatia. The study included 250 acute stroke patients admitted to University Department of Neurology, Osijek University Hospital Centre in 2011. Patients were grouped according to age, gender, subtypes and recurrence of stroke. The study showed significant differences in the distribution of cigarette smoking, diabetes, cardiomyopathy and hyperuricemia according to patient age...
March 2018: Acta Clinica Croatica
Agnieszka Zienciuk-Krajka, Maciej Sterliński, Artur Filipecki, Radosław Owczuk, Jacek Bednarek, Maciej Kempa, Sławomir Sielski, Marcin Dziduszko, Przemysław Mitkowski, Jarosław Kaźmierczak, Jacek Kuśnierz, Dariusz Michałkiewicz, Sebastian M Stec, Marcin Gułaj, Ryszard Majcherek, Andrzej Lubiński, Grzegorz Raczak
BACKGROUND: Implantable cardioverter-defibrillator (ICD) therapy has been proven effective in prevention of sudden cardiac death (SCD), but data on outcomes for ICD therapy in the young and otherwise healthy Long QT Syndrome (LQTS) population are limited. AIMS: To collect data on appropriate and inappropriate ICD discharges, risk factors, and ICD-related complications. METHODS: All LQTS patients implanted with an ICD in 14 centres were investigated, and demographical, clinical and data on ICD therapy were collected...
September 25, 2018: Kardiologia Polska
Minetaka Maeda, Kageyuki Oba, Satoshi Yamaguchi, Osamu Arasaki, Masataka Sata, Hiroaki Masuzaki, Michio Shimabukuro
Although increasing evidence suggests that epicardial adipose tissue volume (EATV) is associated with post-ablation atrial fibrillation (AF), ranges of EATV predictive of post-ablation recurrence of AF remain unclear. In this study, we evaluated: (1) relationships between EATV and characteristics of AF, (2) impact of EATV on recurrent AF after radiofrequency ablation; , and (3) cut-off point for recurrent AF using a receiver operating characteristic curve. In 218 consecutive symptomatic patients undergoing who underwent ablation for AF (143 paroxysmal AF; 78 persistent AF), the EATV index (EATVI: EATV/body surface area, mL/m2 ) was measured using 320-row multidetector computed tomography...
August 21, 2018: American Journal of Cardiology
Avi Sabbag, Xiaoxi Yao, Konstantinos C Siontis, Peter A Noseworthy
The burden of atrial fibrillation (AF) is projected to increase substantially over the next decade in parallel with the aging of the population. The increasing age, level of comorbidity, and polypharmacy will complicate the treatment of older adults with AF. For instance, advanced age and chronic kidney disease have been shown to increase the risk of both thromboembolism and bleeding in patients with AF. Frailty, recurrent falls and polypharmacy, while very common among elderly patients with AF, are often overlooked in the clinical decision making despite their significant interaction with oral anticoagulant (OAC) and profound impact on the patient's clinical outcomes...
October 2018: Korean Circulation Journal
Antonio Gómez-Outes, Mª Luisa Suárez-Gea, Jose Manuel García-Pinilla
Stroke is a significant source of morbidity and mortality in developed countries. Cardioembolic strokes represent approximately 15-30% of all ischemic strokes. They are frequently related to atrial fibrillation (AF) and have a worse prognosis and high recurrence rates when compared to other causes (e.g. atherosclerosis). Areas covered: This review includes a summary of general and specific scores to assess cardiovascular and stroke risks, with a focus on specific scores available in AF. Recommendations for antithrombotic therapy are also reviewed...
September 2018: Expert Opinion on Pharmacotherapy
Shunsuke Tomomori, Yukiko Nakano, Hidenori Ochi, Yuko Onohara, Akinori Sairaku, Takehito Tokuyama, Chikaaki Motoda, Hiroya Matsumura, Michitaka Amioka, Naoya Hironobe, Yousaku Ookubo, Shou Okamura, Hiroshi Kawazoe, Kazuaki Chayama, Yasuki Kihara
INTRODUCTION: The single nucleotide polymorphism (SNP) rs2106261 in the transcription factor gene ZFHX3 (16q22), a major regulator of inflammation, has been reported linking to atrial fibrillation (AF) by genome-wide association studies. Inflammation is known to be a strong predictor of atrial fibrillation recurrence after ablation, so we examined the association of the ZFHX3 SNP rs2106261 to inflammation marker expression and recurrence after AF ablation. METHODS: We genotyped ZFHX3 SNP rs2106261 and compared the minor (T) allele frequency between 362 paroxysmal AF (PAF) patients underwent pulmonary vein isolation (PVI) and 627 non-AF controls...
2018: PloS One
Shun-Ichiro Sakamoto, Atsushi Hiromoto, Yosuke Ishii, Takashi Sasaki, Yasuo Miyagi, Takashi Nitta
PURPOSE: We examined the outcome of modified-maze procedures reflecting a single-center strategy in the treatment of atrial fibrillation (AF) associated with atrial septal defect (ASD) in adults. METHODS: A retrospective chart review was performed for 29 patients who underwent surgical ASD closure and 2 types of maze procedures (full and simplified maze procedures) for AF. The outcome related to the each procedure was examined. A Cox proportional hazards analysis was performed to assess the independent predictors of AF and atrial tachycardia (AT) recurrence...
September 3, 2018: Surgery Today
Hai Deng, Alena Shantsila, Pi Guo, Tatjana S Potpara, Xianzhang Zhan, Xianhong Fang, Hongtao Liao, Yang Liu, Wei Wei, Lu Fu, Shulin Wu, Yumei Xue, Gregory Y H Lip
BACKGROUND: Obesity or overweight is related to worse outcomes in patients with atrial fibrillation (AF) following catheter ablation (CA). The role of being underweight in relation to recurrent arrhythmias post AF ablation is less certain. We conducted a retrospective study to investigate the association of body mass index (BMI) with arrhythmia outcomes in AF patients undergoing CA. METHODS: In a cohort of 1410 AF patients (mean age 57.2 ± 11.6 years; 68% male) undergoing single CA, the association between BMI and AF ablation outcome was analyzed using BMI as a continuous variable and by four BMI categories (<18...
August 30, 2018: EBioMedicine
Tal Frenkel Rutenberg, Ran Rutenberg, Maria Vitenberg, Nir Cohen, Yichayaou Beloosesky, Steven Velkes
PURPOSE: To define risk factors for rehospitalization following fragility hip fractures and to create a predictive model. METHODS: A retrospective cohort study of patients 65 years and older, who were treated operatively following fragility hip fractures between 01.2011 and 06.2016. Patients were allocated into two study groups based on the occurrence of recurrent hospitalizations in the year following surgery. Demographic information, comorbidities, and in-hospital characteristics were collected, as was information regarding 1-year readmissions...
August 23, 2018: European Journal of Trauma and Emergency Surgery: Official Publication of the European Trauma Society
Creuza M Goes, Paola P N F Falcochio, Luciano F Drager
In the last decades, consistent data derived from experimental, epidemiological, and clinical studies pointed obstructive sleep apnea (OSA), the most common sleep disordered breathing worldwide, as a potential risk factor for incidence and recurrence of atrial fibrillation (AF). Areas covered: This review article describes the impact of OSA on AF and discusses potential strategies for managing OSA in the AF scenario. Expert commentary: Untreated OSA seems to be one important predictor of AF treatment failure after chemical or electrical cardioversion as well as after a successful AF ablation...
September 3, 2018: Expert Review of Cardiovascular Therapy
V A Brazhnik, L O Minushkina, M A Evdokimova, A S Galyavich, S N Tereshchenko, N A Koziolova, M G Glezer, A V Yagoda, E V Khorolets, E N Dankovtseva, O I Boeva, V O Konstantinov, D A Zateishchikov
PURPOSE: to analyze possible associations of clinical and genetic factors with development of ischemic stroke after exacerbation of ischemic heart disease (IHD). MATERIALS AND METHODS: The Russian multicenter study aimed at assessment of risk of unfavorable outcomes after exacerbation of IHD "Exacerbation of IHD: logical probabilistic ways to course prognostication for optimization of treatment" (meaning of Cyrillic acronym - oracle) was conducted in 16 centers of 7 cities in Russia...
July 2018: Kardiologiia
Z G Tatarintseva, E D Kosmachyeva, V A Porhanov
OBJECTIVE: to analyze patients with first-time developing atrial fibrillation (AF), against acute coronary syndrome (ACS), risk factors for arrhythmia, assessment of patients' adherence to oral anticoagulant therapy 6-24 months after the ACS episode, according to the total ACS registry for the Krasnodar Territory. MATERIALS AND METHODS: A retrospective analysis of the case histories of 13,244 patients admited to the infarction departments of all setlements of the Krasnodar Territory without exception and included in the ACS registry for the Krasnodar Territory from November 20, 2015 to January 20, 2018...
2018: Kardiologiia
Ya-Fu Tan, Li-Xuan Zhan, Xiao-Hui Chen, Jian-Jun Guo, Chao Qin, En Xu
It is unanimously accepted that stroke is a highly heterogeneous disorder. Different subtypes of ischemic stroke may have different risk factors, clinical features, and prognoses. The aim of this study was to evaluate the risk factors, clinical characteristics, and prognoses of different subtypes of ischemic stroke defined by the Trial of ORG10172 in Acute Stroke Treatment (TOAST) criteria. We prospectively analyzed the data from 530 consecutive patients who were admitted to our hospital with acute ischemic stroke within 7 days of stroke onset during the study period...
April 2018: Current medical science
Jeremy A Miles, Leonid Garber, Subha Ghosh, Daniel M Spevack
BACKGROUND: Transthoracic echocardiography (TTE) has become routine as part of initial stroke workup to assess for sources of emboli. Few studies have looked at other TTE findings such as ejection fraction, wall motion abnormalities, valve disease, pulmonary hypertension and left ventricular hypertrophy and their association with various subtypes of stroke, long-term outcomes of recurrent stroke, and all-cause mortality. METHODS AND RESULTS: Computed tomography and magnetic resonance imaging brain imaging and TTE reports were reviewed for 2464 consecutive patients referred for TTE as part of a workup for acute stroke between 1/1/01 and 9/30/07...
July 30, 2018: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
R Jay Widmer, Erin A Fender, David O Hodge, Kristi H Monahan, Lauri A Peterson, David R Holmes, Douglas L Packer
OBJECTIVES: This study sought to identify clinical and procedural risk factors associated with pulmonary vein (PV) restenosis. BACKGROUND: Pulmonary vein stenosis (PVS) is a rare but morbid complication of PV isolation for atrial fibrillation (AF) ablation. Interventions such as PV balloon angioplasty (BA) or stenting achieve excellent acute success; however, subsequent restenosis is common. METHODS: A total of 113 patients underwent invasive treatment for severe PVS between 2000 and 2014 and were followed prospectively...
April 2018: JACC. Clinical Electrophysiology
Xin-Hua Wang, Zheng Li, Jia-Liang Mao, Min-Hua Zang, Jun Pu
BACKGROUND: The prevalence, risk factors of left atrial low voltage areas (LVA) in paroxysmal atrial fibrillation (PAF) and the impact of LVA on the effectiveness of circumferential pulmonary vein isolation (CPVI) were not fully clarified. METHODS: One hundred fifty patients (mean age 64.7 years, 89 males) with PAF were consecutively enrolled to undergo CPVI. Prior to ablation a contact force sensing ablation catheter was utilized for LVA mapping in sinus rhythm...
July 19, 2018: International Journal of Cardiology
Charles Guenancia, Clémence Toucas, Laurent Fauchier, Karim Stamboul, Fabien Garnier, Basile Mouhat, Audrey Sagnard, Luc Lorgis, Marianne Zeller, Yves Cottin
Aims: Silent and symptomatic atrial fibrillation (AF) are common during acute myocardial infarction (AMI), and associated with higher in-hospital and 1-year mortality. Are silent and symptomatic AF associated with higher rates of AF recurrence after hospitalization for AMI? Methods and results: All consecutive patients admitted for AMI between January 2012 and August 2015 were prospectively analysed by continuous electrocardiogram monitoring <48 h after admission...
July 27, 2018: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
Keiko Shimamoto, Fumiharu Miura, Yuji Shimatani, Kenji Nishioka, Ichiro Inoue
PURPOSE: Catheter ablation of atrial fibrillation (AF) is an effective therapy for selected groups of patients. We evaluated whether quantification of left atrium (LA) or pulmonary vein (PV) by using multi-detector computed tomography (MDCT) may predict the success rate of PV isolation procedure. METHODS: We included 118 patients younger than 65 years with symptomatic AF (73 paroxysmal, PAF; 45 non-paroxysmal, non-PAF). All patients underwent 256-slice MDCT prior to circumferential PV isolation to evaluate anatomy, volume and dimensions of LA and PV...
2018: PloS One
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