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atrial fibrillation recurrence risk factors

V A Brazhnik, L O Minushkina, M A Evdokimova, A S Galyavich, S N Tereshchenko, N A Koziolova, M G Glezer, A V Yagoda, E V Khorolets, E N Dankovtseva, O I Boeva, V O Konstantinov, D A Zateishchikov
PURPOSE: to analyze possible associations of clinical and genetic factors with development of ischemic stroke after exacerbation of ischemic heart disease (IHD). MATERIALS AND METHODS: The Russian multicenter study aimed at assessment of risk of unfavorable outcomes after exacerbation of IHD "Exacerbation of IHD: logical probabilistic ways to course prognostication for optimization of treatment" (meaning of Cyrillic acronym - oracle) was conducted in 16 centers of 7 cities in Russia...
July 2018: Kardiologiia
Z G Tatarintseva, E D Kosmachyeva, V A Porhanov
OBJECTIVE: to analyze patients with first-time developing atrial fibrillation (AF), against acute coronary syndrome (ACS), risk factors for arrhythmia, assessment of patients' adherence to oral anticoagulant therapy 6-24 months after the ACS episode, according to the total ACS registry for the Krasnodar Territory. MATERIALS AND METHODS: A retrospective analysis of the case histories of 13,244 patients admited to the infarction departments of all setlements of the Krasnodar Territory without exception and included in the ACS registry for the Krasnodar Territory from November 20, 2015 to January 20, 2018...
2018: Kardiologiia
Ya-Fu Tan, Li-Xuan Zhan, Xiao-Hui Chen, Jian-Jun Guo, Chao Qin, En Xu
It is unanimously accepted that stroke is a highly heterogeneous disorder. Different subtypes of ischemic stroke may have different risk factors, clinical features, and prognoses. The aim of this study was to evaluate the risk factors, clinical characteristics, and prognoses of different subtypes of ischemic stroke defined by the Trial of ORG10172 in Acute Stroke Treatment (TOAST) criteria. We prospectively analyzed the data from 530 consecutive patients who were admitted to our hospital with acute ischemic stroke within 7 days of stroke onset during the study period...
April 2018: Current medical science
Jeremy A Miles, Leonid Garber, Subha Ghosh, Daniel M Spevack
BACKGROUND: Transthoracic echocardiography (TTE) has become routine as part of initial stroke workup to assess for sources of emboli. Few studies have looked at other TTE findings such as ejection fraction, wall motion abnormalities, valve disease, pulmonary hypertension and left ventricular hypertrophy and their association with various subtypes of stroke, long-term outcomes of recurrent stroke, and all-cause mortality. METHODS AND RESULTS: Computed tomography and magnetic resonance imaging brain imaging and TTE reports were reviewed for 2464 consecutive patients referred for TTE as part of a workup for acute stroke between 1/1/01 and 9/30/07...
July 30, 2018: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
R Jay Widmer, Erin A Fender, David O Hodge, Kristi H Monahan, Lauri A Peterson, David R Holmes, Douglas L Packer
OBJECTIVES: This study sought to identify clinical and procedural risk factors associated with pulmonary vein (PV) restenosis. BACKGROUND: Pulmonary vein stenosis (PVS) is a rare but morbid complication of PV isolation for atrial fibrillation (AF) ablation. Interventions such as PV balloon angioplasty (BA) or stenting achieve excellent acute success; however, subsequent restenosis is common. METHODS: A total of 113 patients underwent invasive treatment for severe PVS between 2000 and 2014 and were followed prospectively...
April 2018: JACC. Clinical Electrophysiology
Xin-Hua Wang, Zheng Li, Jia-Liang Mao, Min-Hua Zang, Jun Pu
BACKGROUND: The prevalence, risk factors of left atrial low voltage areas (LVA) in paroxysmal atrial fibrillation (PAF) and the impact of LVA on the effectiveness of circumferential pulmonary vein isolation (CPVI) were not fully clarified. METHODS: One hundred fifty patients (mean age 64.7 years, 89 males) with PAF were consecutively enrolled to undergo CPVI. Prior to ablation a contact force sensing ablation catheter was utilized for LVA mapping in sinus rhythm...
July 19, 2018: International Journal of Cardiology
Charles Guenancia, Clémence Toucas, Laurent Fauchier, Karim Stamboul, Fabien Garnier, Basile Mouhat, Audrey Sagnard, Luc Lorgis, Marianne Zeller, Yves Cottin
Aims: Silent and symptomatic atrial fibrillation (AF) are common during acute myocardial infarction (AMI), and associated with higher in-hospital and 1-year mortality. Are silent and symptomatic AF associated with higher rates of AF recurrence after hospitalization for AMI? Methods and results: All consecutive patients admitted for AMI between January 2012 and August 2015 were prospectively analysed by continuous electrocardiogram monitoring <48 h after admission...
July 27, 2018: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
Keiko Shimamoto, Fumiharu Miura, Yuji Shimatani, Kenji Nishioka, Ichiro Inoue
PURPOSE: Catheter ablation of atrial fibrillation (AF) is an effective therapy for selected groups of patients. We evaluated whether quantification of left atrium (LA) or pulmonary vein (PV) by using multi-detector computed tomography (MDCT) may predict the success rate of PV isolation procedure. METHODS: We included 118 patients younger than 65 years with symptomatic AF (73 paroxysmal, PAF; 45 non-paroxysmal, non-PAF). All patients underwent 256-slice MDCT prior to circumferential PV isolation to evaluate anatomy, volume and dimensions of LA and PV...
2018: PloS One
Hailong Cao, Wei Xu, Xin Chen, Qing Zhou, Rongfang Lan, Yijiang Chen, Dongjin Wang
Receptor activator of nuclear factor-κB ligand (RANKL) had been confirmed contributing to the development and progression of AF by regulating atrial structural remodeling. But the involved genetic mechanism is unknown. We intended to explore the association between the polymorphism RANKL -1816C>G (rs7984870) and susceptibility and prognosis of lone AF. RANKL rs7984870 was genotyped in a case-control study of 828 patients and 834 controls in Chinese population. The CG and/or CC genotypes had an increased lone AF risk [adjusted odds ratio (OR) 1...
July 24, 2018: Heart and Vessels
Saket R Sanghai, Mayank Sardana, Barinder Hansra, Darleen M Lessard, Seth T Dahlberg, Gerard P Aurigemma, Timothy P Fitzgibbons, David D McManus
Background: Epicardial adipose tissue (EAT) has been associated with adverse left atrial (LA) remodeling and atrial fibrillation (AF) outcomes, possibly because of paracrine signaling. Objectives: We examined factors associated with a novel measure of EAT i.e., indexed LAEAT (iLAEAT) and its prognostic significance after catheter ablation (CA) of atrial fibrillation (AF). Methods: We performed a retrospective analysis of 274 participants with AF referred for CA. LAEAT area was measured from a single pre-ablation CT image and indexed to body surface area (BSA) to calculate iLAEAT...
2018: Frontiers in Cardiovascular Medicine
Ivo Roca-Luque, Nuria Rivas-Gándara, Laura Dos Subirà, Jaume Francisco Pascual, Antònia Pijuan-Domenech, Jordi Pérez-Rodon, M Teresa Subirana-Domenech, Alba Santos-Ortega, Ferran Rosés-Noguer, Berta Miranda-Barrio, Ignacio Ferreira-Gonzalez, Jaume Casaldàliga Ferrer, David García-Dorado García, Angel Moya Mitjans
OBJECTIVES: The aim of this study was to analyze the long-term outcomes after intra-atrial re-entrant tachycardia (IART) ablation in congenital heart disease (CHD). BACKGROUND: IART increases morbidity and mortality in CHD patients. Radiofrequency catheter ablation has evolved into the first-line treatment of this complication. METHODS: This was a prospective, single-center study of all consecutive CHD patients who underwent first ablation for IART from January 2009 to December 2015 (n = 94, 39...
June 2018: JACC. Clinical Electrophysiology
Aleksandra Liżewska-Springer, Alicja Dąbrowska-Kugacka, Ewa Lewicka, Łukasz Drelich, Tomasz Królak, Grzegorz Raczak
BACKGROUND: Catheter ablation (CA) is a well-known treatment option for patients with symptomatic drug-resistant atrial fibrillation (AF). Multiple factors have been identified to determine AF recurrence after CA, however their predictive value is rather small. Identification of novel predictors of CA outcome is therefore of primary importance to reduce health costs and improve long-term results of this intervention. The recurrence of AF following CA is related to the severity of left ventricular (LV) dysfunction, extend of atrial dilatation and fibrosis...
June 20, 2018: Cardiology Journal
Mattia Arrigo, Shiro Ishihara, Elodie Feliot, Alain Rudiger, Nicolas Deye, Alain Cariou, Bertrand Guidet, Samir Jaber, Marc Leone, Matthieu Resche-Rigon, Antoine Vieillard Baron, Matthieu Legrand, Etienne Gayat, Alexandre Mebazaa
BACKGROUND: Atrial fibrillation (AFib) is associated with adverse outcome in critical illness, but whether this effect is independent from other risk factors remains uncertain. New-onset AFib during critical illness may be independently associated with increased in-hospital and long-term risk of death. METHODS: FROG-ICU was a prospective, observational, multi-centre cohort study designed to investigate the outcome of critically ill patients. Inclusion criteria were invasive mechanical ventilation and/or treatment with a positive inotropic agent for >24 h...
September 1, 2018: International Journal of Cardiology
Tianyu Zhou, Jun Li, Hao Lai, Kai Zhu, Yongxin Sun, Wenjun Ding, Tao Hong, Chunsheng Wang
BACKGROUND: This study aimed to evaluate the clinical trends of mitral valve repair for degenerative mitral regurgitation and the benefit of early surgical intervention on repair durability in a high-volume center. . METHODS: From January 2003 to December 2015, 1903 consecutive patients with severe degenerative mitral regurgitation underwent mitral valve repair at our institution. The timing of surgical intervention was evaluated by guideline-related indications including symptoms, atrial fibrillation, left ventricular dysfunction and pulmonary hypertension...
June 5, 2018: Annals of Thoracic Surgery
Elena A Kochmareva, Valentin A Kokorin, Ivan G Gordeev
OBJECTIVE: Pulmonary embolism (PE) remains one of the leading causes of mortality among cardiovascular diseases. We aimed at investigating risk factors of PE complications in patients with intermediate risk and integrate them into a simple model for its' bedside prediction. METHODS: Among 173 patients with PE, 136 were classified as high or intermediate risk. Patients were retrospectively divided into groups of complicated (n = 44) or uncomplicated (n = 92) course...
June 1, 2018: European Journal of Internal Medicine
Erik T Bieging, Alan Morris, Brent D Wilson, Christopher J McGann, Nassir F Marrouche, Joshua Cates
INTRODUCTION: Multiple markers left atrium (LA) remodeling, including LA shape, correlate with outcomes in atrial fibrillation (AF). Catheter ablation is an important treatment of AF, but better tools are needed to determine which patients will benefit. In this study, we use particle-based modeling to quantitatively assess LA shape, and determine to what degree it predicts AF recurrence after catheter ablation. METHODS AND RESULTS: There were 254 patients enrolled in the DECAAF study who underwent cardiac magnetic resonance imaging of the LA prior to AF ablation and were followed for recurrence for up to 475 days...
July 2018: Journal of Cardiovascular Electrophysiology
Xi Chen, Shi-Dong Chen, Yi Dong, Qiang Dong
BACKGROUND: Previous review from randomized controlled trials (RCT) showed that patients with cryptogenic stroke may benefit from patent foramen ovale (PFO) closure. However, the findings from the systematic review were not clear when observational studies were also included. METHODS: We searched MEDLINE, Embase, and Cochrane databases. The primary endpoints were recurrent stroke or transient ischemic attack (TIA). The secondary outcomes were all-cause death, atrial fibrillation (AF), and hemorrhagic events...
May 27, 2018: CNS Neuroscience & Therapeutics
Dan Liu, Kai Hu, Marie Schmidt, Jonas Müntze, Octavian Maniuc, Daniel Gensler, Daniel Oder, Tim Salinger, Frank Weidemann, Georg Ertl, Stefan Frantz, Christoph Wanner, Peter Nordbeck
OBJECTIVES: To evaluate potential risk factors for stroke or transient ischemic attacks (TIA) and to test the feasibility and efficacy of a Fabry-specific stroke risk score in Fabry disease (FD) patients without atrial fibrillation (AF). BACKGROUND: FD patients often experience cerebrovascular events (stroke/TIA) at young age. METHODS: 159 genetically confirmed FD patients without AF (aged 40 ± 14 years, 42.1% male) were included, and risk factors for stroke/TIA events were determined...
May 24, 2018: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
Sophie Testa, Walter Ageno, Emilia Antonucci, Rossella Morandini, Jan Beyer-Westendorf, Maurizio Paciaroni, Marc Righini, Piera Sivera, Peter Verhamme, Vittorio Pengo, Daniela Poli, Gualtiero Palareti
The management of major bleeding in patients treated with direct oral anticoagulants (DOACs) is still not well established. START-Events, a branch of the START registry (Survey on anTicoagulated pAtients RegisTer) (NCT02219984), aims to describe the actual management of bleeding or recurrent thrombotic events in routine clinical practice. We here present the results of the management of bleeding patients. The START-Event registry is a prospective, observational, multicenter, international study. Baseline characteristics (demographic, clinical, risk factors) of patients, laboratory data at admission and during follow-up, site of bleeding, therapeutic strategies, and outcomes at the time of hospital discharge and after 6 months were recorded on a web-based case report form...
May 22, 2018: Internal and Emergency Medicine
Angeliki Zarkali, Suk Fun Cheng, Agnes Dados, Robert Simister, Arvind Chandratheva
BACKGROUND AND PURPOSE: Ischaemic visual loss is often considered a lower risk factor than other transient ischaemic attacks (TIA). We aimed to determine the recurrence risk, prevalence and management of vascular risk factors in these patients. METHODS: The study took place in the University College Hospital London daily TIA clinic, main referral centre for North-Central London and Moorfields Eye Hospital. Consecutive records for patients with transient (< 24 h) or permanent (> 24 h) ischaemic visual loss were reviewed during the period January 2014-October 2016...
May 17, 2018: Cerebrovascular Diseases
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