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https://www.readbyqxmd.com/read/30539818/paternal-physical-exercise-modulates-global-dna-methylation-status-in-the-hippocampus-of-male-rat-offspring
#1
Christiano Spindler, Ethiane Segabinazi, André Luís Ferreira de Meireles, Francele Valente Piazza, Filipe Mega, Gabriela Dos Santos Salvalaggio, Matilde Achaval, Viviane Rostirola Elsner, Simone Marcuzzo
It is widely known that maternal physical exercise is able to induce beneficial improvements in offspring cognition; however, the effects of paternal exercise have not been explored in detail. The present study was designed to evaluate the impact of paternal physical exercise on memory and learning, neuroplasticity and DNA methylation levels in the hippocampus of male offspring. Adult male Wistar rats were divided into two groups: sedentary or exercised fathers. The paternal preconception exercise protocol consisted of treadmill running, 20 minutes daily, 5 consecutive days per week for 22 days, while the mothers were not trained...
March 2019: Neural Regeneration Research
https://www.readbyqxmd.com/read/30539806/rehabilitation-following-spinal-cord-injury-how-animal-models-can-help-our-understanding-of-exercise-induced-neuroplasticity
#2
REVIEW
Kristina Loy, Florence M Bareyre
Spinal cord injury is a devastating condition that is followed by long and often unsuccessful recovery after trauma. The state of the art approach to manage paralysis and concomitant impairments is rehabilitation, which is the only strategy that has proven to be effective and beneficial for the patients over the last decades. How rehabilitation influences the remodeling of spinal axonal connections in patients is important to understand, in order to better target these changes and define the optimal timing and onset of training...
March 2019: Neural Regeneration Research
https://www.readbyqxmd.com/read/30509989/inherent-auditory-skills-rather-than-formal-music-training-shape-the-neural-encoding-of-speech
#3
Kelsey Mankel, Gavin M Bidelman
Musical training is associated with a myriad of neuroplastic changes in the brain, including more robust and efficient neural processing of clean and degraded speech signals at brainstem and cortical levels. These assumptions stem largely from cross-sectional studies between musicians and nonmusicians which cannot address whether training itself is sufficient to induce physiological changes or whether preexisting superiority in auditory function before training predisposes individuals to pursue musical interests and appear to have similar neuroplastic benefits as musicians...
December 3, 2018: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/30503681/high-intensity-interval-training-on-neuroplasticity-balance-between-brain-derived-neurotrophic-factor-and-precursor-brain-derived-neurotrophic-factor-in-poststroke-depression-rats
#4
Lu Luo, Congqin Li, Yu Deng, Yuyang Wang, Pingping Meng, Qiang Wang
BACKGROUND: High-intensity interval training (HIIT) improves functional and mental health in the patients with stroke. To investigate the potential mechanisms of HIIT on poststroke depression (PSD). METHODS: Wistar rats were randomly divided into control, Sham, PSD, moderate intensity continuous training (MICT), and HIIT groups. After PSD model was successful made, the maximum speed (Smax) and the blood lactate threshold corresponding speed (SLT ) were measured...
November 30, 2018: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/30481530/neuroplastic-and-cognitive-impairment-in-substance-use-disorders-a-therapeutic-potential-of-cognitive-stimulation
#5
REVIEW
Patricia Sampedro-Piquero, David Ladrón de Guevara-Miranda, Francisco J Pavón, Antonia Serrano, Juan Suárez, Fernando Rodríguez de Fonseca, Luis J Santín, Estela Castilla-Ortega
Drug addiction is a chronic and relapsing disorder in which repeated drug exposure compromises brain neuroplasticity. Brain areas normally involved in learning and goal-directed behaviors become corrupted, which may lead to cognitive deficits that coexist with other addiction symptoms and predict a worse treatment outcome. New learning experiences that are not motivated by drugs may improve both cognitive deficits and drug-induced symptoms by promoting adaptive neuroplastic changes that could alleviate or reverse those involved in addiction...
November 24, 2018: Neuroscience and Biobehavioral Reviews
https://www.readbyqxmd.com/read/30457965/effects-on-balance-skills-and-patient-compliance-of-biofeedback-training-with-inertial-measurement-units-and-exergaming-in-subacute-stroke-a-pilot-randomized-controlled-trial
#6
A Lupo, A M Cinnera, A Pucello, M Iosa, P Coiro, S Personeni, Francesca Gimigliano, Giovanni Iolascon, Stefano Paolucci, G Morone
Stroke patients have reduced balance and postural control that limits their activities of daily living and participation in social life. Recently, many exergaming systems based on video-biofeedback have been developed for balance training in neurological conditions, however their efficacy remains to be proven. The aim of this study was to investigate the effects on balance skills and patient compliance of biofeedback training based on inertial measurement units and exergaming in subacute stroke. The enrolled subjects were randomized into two groups: subjects allocated to the experimental group performed 10 sessions of biofeedback balance training using inertial sensors, whereas subjects allocated to the control group performed 10 sessions of conventional balance training...
July 2018: Functional Neurology
https://www.readbyqxmd.com/read/30457355/intermittent-exotropia-treatment-with-dichoptic-visual-training-using-a-unique-virtual-reality-platform
#7
Xue Li, Cheng Yang, Guanrong Zhang, Yan Zhang, Jianqing Lan, Hang Chu, Juan Li, Wenjuan Xie, Shujun Wang, Brenda K Wiederhold, Mark Wiederhold, Li Yan, Jin Zeng
We evaluated the effect of dichoptic visual training based on a unique virtual reality (VR) platform mounted display in patients with intermittent exotropia (IXT). A total of 25 IXT patients (8 men, 17 women) with a mean age of 12.3 years (range, 5-39 year) were recruited. The Hirschberg test, prism and alternate cover testing (with accommodative targets for fixation at 33 cm in all patients), perceptual eye position (PEP), and stereopsis were evaluated after 1, 3, and 6 months of dichoptic visual neuroplasticity training with a computer-controlled perceptual examination evaluation system...
November 17, 2018: Cyberpsychology, Behavior and Social Networking
https://www.readbyqxmd.com/read/30443795/heroin-versus-cocaine-opposite-choice-as-a-function-of-context-but-not-of-drug-history-in-the-rat
#8
Maria Teresa De Luca, Christian Montanari, Maria Meringolo, Laura Contu, Michele Celentano, Aldo Badiani
RATIONALE: Previous studies have shown that rats trained to self-administer heroin and cocaine exhibit opposite preferences, as a function of setting, when tested in a choice paradigm. Rats tested at home prefer heroin to cocaine, whereas rats tested outside the home prefer cocaine to heroin. Here, we investigated whether drug history would influence subsequent drug preference in distinct settings. Based on a theoretical model of drug-setting interaction, we predicted that regardless of drug history rats would prefer heroin at home and cocaine outside the home...
November 15, 2018: Psychopharmacology
https://www.readbyqxmd.com/read/30440915/the-impact-of-alterg-training-on-balance-and-structure-of-vestibulospinal-tract-in-cerebral-palsy-children
#9
Sh Azizi, A H Rasooli, M Soleimani, A Irani, A Shahrokhi, M M Mirbagheri
We aimed to investigate the effects of an antigravity treadmill (AlterG) on the balance and structure of the vestibulospinal tract. The AlterG can reduce the weightbearing of patients and hence can facilitate their locomotion. Three children with cerebral palsy (CP) received AlterG training three days per week for eight weeks with each session lasting 45 minutes. The balance of children was evaluated using the Berg balance test and the Timed Up and Go (TUG) test. The diffusion tensor imaging (DTI) method was employed to quantify changes of the structure of the vestibulospinal tract...
July 2018: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/30440914/assessment-of-neuroplasticity-of-corticospinal-tract-induced-by-antigravity-treadmill-alterg-in-cerebral-palsy-children
#10
Sh Azizi, P M Birgani, H Marzbani, R Nourian, M Kohanpour, M M Mirbagheri
The aim of this study was to assess neuroplasticity that occurred in the corticospinal tract (CST) following antigravity treadmill (AlterG) training. AlterG can facilitate walking by having up to an 80% reduction of weight-bearing in patients. Systematic and intensive gait training for sufficient periods of time may lead to neuroplasticity and walking capacity improvement. AlterG gait training was done for eight weeks, 3 sessions per week, and 45 minutes each session. Three cerebral palsy (CP) children participated in this study...
July 2018: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/30412515/residual-vision-activation-and-the-brain-eye-vascular-triad-dysregulation-plasticity-and-restoration-in-low-vision-and-blindness-a-review
#11
Bernhard A Sabel, Josef Flammer, Lotfi B Merabet
Vision loss due to ocular diseases such as glaucoma, optic neuropathy, macular degeneration, or diabetic retinopathy, are generally considered an exclusive affair of the retina and/or optic nerve. However, the brain, through multiple indirect influences, has also a major impact on functional visual impairment. Such indirect influences include intracerebral pressure, eye movements, top-down modulation (attention, cognition), and emotionally triggered stress hormone release affecting blood vessel dysregulation...
2018: Restorative Neurology and Neuroscience
https://www.readbyqxmd.com/read/30410454/frequency-specific-cortical-dynamics-during-motor-imagery-are-influenced-by-prior-physical-activity
#12
Selina C Wriessnegger, Clemens Brunner, Gernot R Müller-Putz
Motor imagery is often used inducing changes in electroencephalographic (EEG) signals for imagery-based brain-computer interfacing (BCI). A BCI is a device translating brain signals into control signals providing severely motor-impaired persons with an additional, non-muscular channel for communication and control. In the last years, there is increasing interest using BCIs also for healthy people in terms of enhancement or gaming. Most studies focusing on improving signal processing feature extraction and classification methods, but the performance of a BCI can also be improved by optimizing the user's control strategies, e...
2018: Frontiers in Psychology
https://www.readbyqxmd.com/read/30397211/improvement-in-reading-performance-through-training-with-simulated-thalamic-visual-prostheses
#13
Katerina Eleonora K Rassia, John S Pezaris
Simulations of artificial vision are used to provide the researcher an opportunity to explore different aspects of visual prosthesis device design by observing subject performance on various tasks viewed through the simulation. Such studies typically use normal, sighted subjects to measure performance at a given point in time. Relatively few studies examine performance changes longitudinally to quantitatively assess the benefits from a training plan that would be akin to post-implantation rehabilitation. Here, we had six normal, sighted subjects use a standard reading task with daily practice over eight weeks to understand the effects of an intensive training schedule on adaptation to artificial sight...
November 5, 2018: Scientific Reports
https://www.readbyqxmd.com/read/30382877/protocol-for-a-randomised-controlled-trial-of-cognitive-bias-modification-training-during-inpatient-withdrawal-from-alcohol-use-disorder
#14
Victoria Manning, Joshua B B Garfield, Samuel C Campbell, John Reynolds, Petra K Staiger, Jarrad A G Lum, Kate Hall, Reinout W Wiers, Dan I Lubman, Antonio Verdejo-Garcia
BACKGROUND: People with alcohol use disorders often exhibit an "alcohol approach bias", the automatically triggered action tendency to approach alcohol. Approach bias is likely to persist following withdrawal from alcohol, and contribute to the high rate of relapse following withdrawal treatment. Cognitive bias modification (CBM) training has been shown to attenuate approach biases and lead to reduced relapse rates. However, no large multisite trial of CBM specifically within a residential withdrawal treatment setting has previously been conducted...
November 1, 2018: Trials
https://www.readbyqxmd.com/read/30363954/changes-in-the-brain-derived-neurotrophic-factor-are-associated-with-improvements-in-diabetes-risk-factors-after-exercise-training-in-adolescents-with-obesity-the-hearty-randomized-controlled-trial
#15
Jeremy J Walsh, Amedeo D'Angiulli, Jameason D Cameron, Ronald J Sigal, Glen P Kenny, Martin Holcik, Steve Doucette, Angela S Alberga, Denis Prud'homme, Stasia Hadjiyannakis, Katie Gunnell, Gary S Goldfield
Obesity in youth increases the risk of type 2 diabetes (T2D), and both are risk factors for neurocognitive deficits. Exercise attenuates the risk of obesity and T2D while improving cognitive function. In adults, these benefits are associated with the actions of the brain-derived neurotrophic factor (BDNF), a protein critical in modulating neuroplasticity, glucose regulation, fat oxidation, and appetite regulation in adults. However, little research exists in youth. This study examined the associations between changes in diabetes risk factors and changes in BDNF levels after 6 months of exercise training in adolescents with obesity...
2018: Neural Plasticity
https://www.readbyqxmd.com/read/30349505/differentiated-effects-of-robot-hand-training-with-and-without-neural-guidance-on-neuroplasticity-patterns-in-chronic-stroke
#16
Xin Wang, Wan-Wa Wong, Rui Sun, Winnie Chiu-Wing Chu, Kai-Yu Tong
Robot-assisted training combined with neural guided strategy has been increasingly applied to stroke rehabilitation. However, the induced neuroplasticity is seldom characterized. It is still uncertain whether this kind of guidance could enhance the long-term training effect for stroke motor recovery. This study was conducted to explore the clinical improvement and the neurological changes after 20-session guided or non-guided robot hand training using two measures: changes in brain discriminant ability between motor-imagery and resting states revealed from electroencephalography (EEG) signals and changes in brain network variability revealed from resting-state functional magnetic resonance imaging (fMRI) data in 24 chronic stroke subjects...
2018: Frontiers in Neurology
https://www.readbyqxmd.com/read/30342001/event-related-neural-oscillation-changes-following-reasoning-training-in-individuals-with-mild-cognitive-impairment
#17
Raksha A Mudar, Lydia T Nguyen, Justin Eroh, Hsueh-Sheng Chiang, Audette Rackley, Sandra B Chapman
Emerging evidence suggests cognitive training programs targeting higher-order reasoning may strengthen not only cognitive, but also neural functions in individuals with Mild Cognitive Impairment (MCI). However, research on direct measures of training-induced neural changes, derivable from electroencephalography (EEG), is limited. The current pilot study examined effects of Gist Reasoning training (n=16) compared to New Learning training (n=16) in older adults with amnestic MCI on measures of event-related neural oscillations (theta and alpha band power) corresponding to Go/NoGo tasks during basic and superordinate semantic categorization...
October 17, 2018: Brain Research
https://www.readbyqxmd.com/read/30326883/imove-intensive-mobility-training-with-variability-and-error-compared-to-conventional-rehabilitation-for-young-children-with-cerebral-palsy-the-protocol-for-a-single-blind-randomized-controlled-trial
#18
Laura A Prosser, Samuel R Pierce, Timothy R Dillingham, Judy C Bernbaum, Abbas F Jawad
BACKGROUND: Cerebral palsy (CP) is the most common cause of physical disability in children. The best opportunity to maximize lifelong independence is early in motor development when there is the most potential for neuroplastic change, but how best to optimize motor ability during this narrow window remains unknown. We have systematically developed and pilot-tested a novel intervention that incorporates overlapping principles of neurorehabilitation and infant motor learning in a context that promotes upright mobility skill and postural control development...
October 16, 2018: BMC Pediatrics
https://www.readbyqxmd.com/read/30305765/tendon-neuroplastic-training-for-lateral-elbow-tendinopathy-2-case-reports
#19
Patrick Welsh
Objective: To report 2 cases of lateral elbow tendinopathy treated with a novel adaptation of tendon neuroplastic training (TNT). Clinical features: Patient 1: A 61-year-old male machine operator presented with one year of bilateral lateral elbow pain related to his occupation of using torque wrenches. Patient 2: A 37-year-old male electrician presented with two months of recurrent left lateral elbow pain related to repetitive motions of gripping and pulling at work...
August 2018: Journal of the Canadian Chiropractic Association
https://www.readbyqxmd.com/read/30304785/strengthening-the-brain-is-resistance-training-with-blood-flow-restriction-an-effective-strategy-for-cognitive-improvement
#20
Alexander Törpel, Fabian Herold, Dennis Hamacher, Notger G Müller, Lutz Schega
Aging is accompanied by a decrease in physical capabilities (e.g., strength loss) and cognitive decline. The observed bidirectional relationship between physical activity and brain health suggests that physical activities could be beneficial to maintain and improve brain functioning (e.g., cognitive performance). However, the exercise type (e.g., resistance training, endurance training) and their exercise variables (e.g., load, duration, frequency) for an effective physical activity that optimally enhance cognitive performance are still unknown...
October 9, 2018: Journal of Clinical Medicine
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