Ylenia Della Rocca, Enrico Matteo Traini, Oriana Trubiani, Tonino Traini, Antonella Mazzone, Guya Diletta Marconi, Jacopo Pizzicannella, Francesca Diomede
The use of temporary resin for provisional restorations is a fundamental step to maintain the position of prepared teeth, to protect the pulpal vitality and the periodontal health as well as the occlusion. The present study aimed at evaluating the biological effects of two resins used in dentistry for temporary restorations, Coldpac (Yates Motloid) and ProTemp 4™ (3M ESPE ™), and their eluates, in an in vitro model of human gingival fibroblasts (hGFs). The activation of the inflammatory pathway NFκB p65/NLRP3/IL-1β induced by the self-curing resin disks was evaluated by real-time PCR, Western blotting and immunofluorescence analysis...
April 30, 2024: International Journal of Molecular Sciences