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https://www.readbyqxmd.com/read/30342298/rationale-and-design-of-the-pemafibrate-to-reduce-cardiovascular-outcomes-by-reducing-triglycerides-in-patients-with-diabetes-prominent-study
#1
Aruna D Pradhan, Nina P Paynter, Brendan M Everett, Robert J Glynn, Pierre Amarenco, Marshall Elam, Henry Ginsberg, William R Hiatt, Shun Ishibashi, Wolfgang Koenig, Børge G Nordestgaard, Jean-Charles Fruchart, Peter Libby, Paul M Ridker
Observational, genetic, and experimental data indicate that triglyceride rich lipoproteins (TRLs) likely participate causally in atherothrombosis. Yet, robust clinical trial evidence that triglyceride (TG) lowering therapy reduces cardiovascular events remains elusive. The selective peroxisome proliferator-activated receptor alpha modulator (SPPARM-α), pemafibrate, will be used to target residual cardiovascular risk remaining after treatment to reduce low-density lipoprotein cholesterol (LDL-C) in individuals with the dyslipidemia of type 2 diabetes mellitus (T2)...
September 29, 2018: American Heart Journal
https://www.readbyqxmd.com/read/30340794/cost-effectiveness-of-a-primary-care-based-exercise-intervention-in-perimenopausal-women-the-flamenco-project
#2
Zuzana Špacírová, David Epstein, Leticia García-Mochón, Virginia A Aparicio, Milkana Borges-Cosic, M Puerto López Del Amo, José J Martín-Martín
OBJECTIVE: Adequate physical activity levels and a healthy lifestyle may prevent all kinds of non-communicable diseases, promote well-being and reduce health-care costs among perimenopausal women. This study assessed an exercise programme for perimenopausal women. METHOD: A total of 150 women (aged 45-64 years) not engaged in regular physical activity were randomly assigned to either a 16 week exercise intervention or to the control group. The study was conducted from the perspective of the National Health System...
October 16, 2018: Gaceta Sanitaria
https://www.readbyqxmd.com/read/30339442/search-for-pair-produced-resonances-each-decaying-into-at-least-four-quarks-in-proton-proton-collisions-at-sqrt-s-13-tev
#3
A M Sirunyan, A Tumasyan, W Adam, F Ambrogi, E Asilar, T Bergauer, J Brandstetter, M Dragicevic, J Erö, A Escalante Del Valle, M Flechl, R Frühwirth, V M Ghete, J Hrubec, M Jeitler, N Krammer, I Krätschmer, D Liko, T Madlener, I Mikulec, N Rad, H Rohringer, J Schieck, R Schöfbeck, M Spanring, D Spitzbart, A Taurok, W Waltenberger, J Wittmann, C-E Wulz, M Zarucki, V Chekhovsky, V Mossolov, J Suarez Gonzalez, E A De Wolf, D Di Croce, X Janssen, J Lauwers, M Pieters, M Van De Klundert, H Van Haevermaet, P Van Mechelen, N Van Remortel, S Abu Zeid, F Blekman, J D'Hondt, I De Bruyn, J De Clercq, K Deroover, G Flouris, D Lontkovskyi, S Lowette, I Marchesini, S Moortgat, L Moreels, Q Python, K Skovpen, S Tavernier, W Van Doninck, P Van Mulders, I Van Parijs, D Beghin, B Bilin, H Brun, B Clerbaux, G De Lentdecker, H Delannoy, B Dorney, G Fasanella, L Favart, R Goldouzian, A Grebenyuk, A K Kalsi, T Lenzi, J Luetic, N Postiau, E Starling, L Thomas, C Vander Velde, P Vanlaer, D Vannerom, Q Wang, T 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Arenton, P Barria, B Cox, R Hirosky, M Joyce, A Ledovskoy, H Li, C Neu, T Sinthuprasith, Y Wang, E Wolfe, F Xia, R Harr, P E Karchin, N Poudyal, J Sturdy, P Thapa, S Zaleski, M Brodski, J Buchanan, C Caillol, D Carlsmith, S Dasu, L Dodd, B Gomber, M Grothe, M Herndon, A Hervé, U Hussain, P Klabbers, A Lanaro, A Levine, K Long, R Loveless, T Ruggles, A Savin, N Smith, W H Smith, N Woods
This Letter presents the results of a search for pair-produced particles of masses above 100 GeV that each decay into at least four quarks. Using data collected by the CMS experiment at the LHC in 2015-2016, corresponding to an integrated luminosity of 38.2  fb^{-1}, reconstructed particles are clustered into two large jets of similar mass, each consistent with four-parton substructure. No statistically significant excess of data over the background prediction is observed in the distribution of average jet mass...
October 5, 2018: Physical Review Letters
https://www.readbyqxmd.com/read/30339440/observation-of-the-z%C3%A2-%C3%AF-%C3%A2-%C3%A2-decay-in-pp-collisions-at-sqrt-s-13-tev
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Zhang, M Alhusseini, B Bilki, W Clarida, K Dilsiz, S Durgut, R P Gandrajula, M Haytmyradov, V Khristenko, J-P Merlo, A Mestvirishvili, A Moeller, J Nachtman, H Ogul, Y Onel, F Ozok, A Penzo, C Snyder, E Tiras, J Wetzel, B Blumenfeld, A Cocoros, N Eminizer, D Fehling, L Feng, A V Gritsan, W T Hung, P Maksimovic, J Roskes, U Sarica, M Swartz, M Xiao, C You, A Al-Bataineh, P Baringer, A Bean, S Boren, J Bowen, A Bylinkin, J Castle, S Khalil, A Kropivnitskaya, D Majumder, W Mcbrayer, M Murray, C Rogan, S Sanders, E Schmitz, J D Tapia Takaki, Q Wang, A Ivanov, K Kaadze, D Kim, Y Maravin, D R Mendis, T Mitchell, A Modak, A Mohammadi, L K Saini, N Skhirtladze, F Rebassoo, D Wright, A Baden, O Baron, A Belloni, S C Eno, Y Feng, C Ferraioli, N J Hadley, S Jabeen, G Y Jeng, R G Kellogg, J Kunkle, A C Mignerey, F Ricci-Tam, Y H Shin, A Skuja, S C Tonwar, K Wong, D Abercrombie, B Allen, V Azzolini, A Baty, G Bauer, R Bi, S Brandt, W Busza, I A Cali, M D'Alfonso, Z Demiragli, G Gomez Ceballos, M Goncharov, P Harris, D Hsu, M Hu, Y Iiyama, G M Innocenti, M Klute, D Kovalskyi, Y-J Lee, P D Luckey, B Maier, A C Marini, C Mcginn, C Mironov, S Narayanan, X Niu, C Paus, C Roland, G Roland, G S F Stephans, K Sumorok, K Tatar, D Velicanu, J Wang, T W Wang, B Wyslouch, S Zhaozhong, A C Benvenuti, R M Chatterjee, A Evans, P Hansen, S Kalafut, Y Kubota, Z Lesko, J Mans, S Nourbakhsh, N Ruckstuhl, R Rusack, J Turkewitz, M A Wadud, J G Acosta, S Oliveros, E Avdeeva, K Bloom, D R Claes, C Fangmeier, F Golf, R Gonzalez Suarez, R Kamalieddin, I Kravchenko, J Monroy, J E Siado, G R Snow, B Stieger, A Godshalk, C Harrington, I Iashvili, A Kharchilava, D Nguyen, A Parker, S Rappoccio, B Roozbahani, G Alverson, E Barberis, C Freer, A Hortiangtham, D M Morse, T Orimoto, R Teixeira De Lima, T Wamorkar, B Wang, A Wisecarver, D Wood, S Bhattacharya, O Charaf, K A Hahn, N Mucia, N Odell, M H Schmitt, K Sung, M Trovato, M Velasco, R Bucci, N Dev, M Hildreth, K Hurtado Anampa, C Jessop, D J Karmgard, N Kellams, K Lannon, W Li, N Loukas, N Marinelli, F Meng, C Mueller, Y Musienko, M Planer, A Reinsvold, R Ruchti, P Siddireddy, G Smith, S Taroni, M Wayne, A Wightman, M Wolf, A Woodard, J Alimena, L Antonelli, B Bylsma, L S Durkin, S Flowers, B Francis, A Hart, C Hill, W Ji, T Y Ling, W Luo, B L Winer, H W Wulsin, S Cooperstein, P Elmer, J Hardenbrook, P Hebda, S Higginbotham, A Kalogeropoulos, D Lange, M T Lucchini, J Luo, D Marlow, K Mei, I Ojalvo, J Olsen, C Palmer, P Piroué, J Salfeld-Nebgen, D Stickland, C Tully, S Malik, S Norberg, A Barker, V E Barnes, S Das, L Gutay, M Jones, A W Jung, A Khatiwada, B Mahakud, D H Miller, N Neumeister, C C Peng, H Qiu, J F Schulte, J Sun, F Wang, R Xiao, W Xie, T Cheng, J Dolen, N Parashar, Z Chen, K M Ecklund, S Freed, F J M Geurts, M Kilpatrick, W Li, B Michlin, B P Padley, J Roberts, J Rorie, W Shi, Z Tu, J Zabel, A Zhang, A Bodek, P de Barbaro, R Demina, Y T Duh, J L Dulemba, C Fallon, T Ferbel, M Galanti, A Garcia-Bellido, J Han, O Hindrichs, A Khukhunaishvili, K H Lo, P Tan, R Taus, M Verzetti, A Agapitos, J P Chou, Y Gershtein, T A Gómez Espinosa, E Halkiadakis, M Heindl, E Hughes, S Kaplan, R Kunnawalkam Elayavalli, S Kyriacou, A Lath, R Montalvo, K Nash, M Osherson, H Saka, S Salur, S Schnetzer, D Sheffield, S Somalwar, R Stone, S Thomas, P Thomassen, M Walker, A G Delannoy, J Heideman, G Riley, K Rose, S Spanier, K Thapa, O Bouhali, A Castaneda Hernandez, A Celik, M Dalchenko, M De Mattia, A Delgado, S Dildick, R Eusebi, J Gilmore, T Huang, T Kamon, S Luo, R Mueller, Y Pakhotin, R Patel, A Perloff, L Perniè, D Rathjens, A Safonov, A Tatarinov, N Akchurin, J Damgov, F De Guio, P R Dudero, S Kunori, K Lamichhane, S W Lee, T Mengke, S Muthumuni, T Peltola, S Undleeb, I Volobouev, Z Wang, S Greene, A Gurrola, R Janjam, W Johns, C Maguire, A Melo, H Ni, K Padeken, J D Ruiz Alvarez, P Sheldon, S Tuo, J Velkovska, M Verweij, Q Xu, M W Arenton, P Barria, B Cox, R Hirosky, M Joyce, A Ledovskoy, H Li, C Neu, T Sinthuprasith, Y Wang, E Wolfe, F Xia, R Harr, P E Karchin, N Poudyal, J Sturdy, P Thapa, S Zaleski, M Brodski, J Buchanan, C Caillol, D Carlsmith, S Dasu, L Dodd, S Duric, B Gomber, M Grothe, M Herndon, A Hervé, U Hussain, P Klabbers, A Lanaro, A Levine, K Long, R Loveless, T Ruggles, A Savin, N Smith, W H Smith, N Woods
This Letter presents the observation of the rare Z boson decay Z→ψℓ^{+}ℓ^{-}. Here, ψ represents contributions from direct J/ψ and ψ(2S)→J/ψX, ℓ^{+}ℓ^{-} is a pair of electrons or muons, and the J/ψ meson is detected via its decay to μ^{+}μ^{-}. The sample of proton-proton collision data, collected by the CMS experiment at the LHC at a center-of-mass energy of 13 TeV, corresponds to an integrated luminosity of 35.9  fb^{-1}. The signal is observed with a significance in excess of 5 standard deviations...
October 5, 2018: Physical Review Letters
https://www.readbyqxmd.com/read/30339438/first-accurate-normalization-of-the-%C3%AE-delayed-%C3%AE-decay-of-16-n-and-implications-for-the-12-c-%C3%AE-%C3%AE-16-o-astrophysical-reaction-rate
#5
O S Kirsebom, O Tengblad, R Lica, M Munch, K Riisager, H O U Fynbo, M J G Borge, M Madurga, I Marroquin, A N Andreyev, T A Berry, E R Christensen, P Díaz Fernández, D T Doherty, P Van Duppen, L M Fraile, M C Gallardo, P T Greenlees, L J Harkness-Brennan, N Hubbard, M Huyse, J H Jensen, H Johansson, B Jonson, D S Judson, J Konki, I Lazarus, M V Lund, N Marginean, R Marginean, A Perea, C Mihai, A Negret, R D Page, V Pucknell, P Rahkila, O Sorlin, C Sotty, J A Swartz, H B Sørensen, H Törnqvist, V Vedia, N Warr, H De Witte
The ^{12}C(α,γ)^{16}O reaction plays a central role in astrophysics, but its cross section at energies relevant for astrophysical applications is only poorly constrained by laboratory data. The reduced α width, γ_{11}, of the bound 1^{-} level in ^{16}O is particularly important to determine the cross section. The magnitude of γ_{11} is determined via sub-Coulomb α-transfer reactions or the β-delayed α decay of ^{16}N, but the latter approach is presently hampered by the lack of sufficiently precise data on the β-decay branching ratios...
October 5, 2018: Physical Review Letters
https://www.readbyqxmd.com/read/30339363/correction-to-a-trimethoprim-conjugate-of-thiomaltose-has-enhanced-antibacterial-efficacy-in-vivo
#6
Xiaojian Wang, Clarissa A Borges, Xinghai Ning, Mohammad Rafi, Jingtuo Zhang, Bora Park, Kiyoko Takemiya, Carlo Lo Sterzo, W Robert Taylor, Lee Riley, Niren Murthy
No abstract text is available yet for this article.
October 19, 2018: Bioconjugate Chemistry
https://www.readbyqxmd.com/read/30339141/-informational-alphabetization-tool-directed-to-people-who-work-in-the-medical-sciences-libraries-in-artemisa-province-cuba
#7
Edwar Parra, Lareisy Borges Damas
The performance of librarians in the medical sciences is enhanced by identifying their training needs through the use of an information literacy tool. We performed this study between 2016 and 2017 with the staff of the medical libraries network at Artemisa province in Cuba. In the first stage of the study we assessed the initial state of the staff's information literacy, and in a second stage, we used empiri-cal and theoretical methods to propose an information literacy tool in digital format. The methodology used was based on educational software...
October 12, 2018: Medwave
https://www.readbyqxmd.com/read/30338020/the-predictability-of-peak-oxygen-consumption-using-submaximal-ratings-of-perceived-exertion-in-adolescents
#8
Danilo V Tolusso, Ward C Dobbs, Michael R Esco
Rating of perceived exertion (RPE) extrapolation involves mathematically extending the submaximal relationship between RPE and oxygen consumption (VO2 ) to maximal intensity. This technique allows practitioners to forego, potentially dangerous, maximal exertion testing while attaining accurate measures of maximal oxygen consumption used for exercise prescription. This method has been proven accurate in adults, but much less in known when applied to an adolescent population. The purpose of this study was to assess the accuracy of the RPE extrapolation as method for estimating VO2max in adolescents...
2018: International Journal of Exercise Science
https://www.readbyqxmd.com/read/30335871/1%C3%A2%C2%BA-posicionamento-brasileiro-sobre-o-impacto-dos-dist%C3%A3%C2%BArbios-de-sono-nas-doen%C3%A3-as-cardiovasculares-da-sociedade-brasileira-de-cardiologia
#9
Luciano F Drager, Geraldo Lorenzi-Filho, Fatima Dumas Cintra, Rodrigo P Pedrosa, Lia R A Bittencourt, Dalva Poyares, Carolina Gonzaga Carvalho, Sonia Maria Guimarães Pereira Togeiro Moura, Rogerio Santos-Silva, Pedro F C de Bruin, Glaucylara R Geovanini, Felipe N Albuquerque, Wercules Antonio Alves de Oliveira, Gustavo A Moreira, Linda Massako Ueno, Flávia Baggio Nerbass, Maria Urbana Pinto Brandão Rondon, Eline Rozária Ferreira Barbosa, Adriana Bertolami, Angelo Amato Vincenzo de Paola, Betânia Braga Silva Marques, Camila Futado Rizzi, Carlos Eduardo Negrão, Carlos Henrique Gomes Uchôa, Cristiane Maki-Nunes, Denis Martinez, Edmundo Arteaga Fernández, Fabrizio U Maroja, Fernanda R Almeida, Ivani C Trombetta, Luciana J Storti, Luiz Aparecido Bortolotto, Marco Túlio de Mello, Melania Aparecida Borges, Monica Levy Andersen, Natanael de Paula Portilho, Paula Macedo, Rosana Alves, Sergio Tufik, Simone C Fagondes, Thaís Telles Risso
No abstract text is available yet for this article.
August 2018: Arquivos Brasileiros de Cardiologia
https://www.readbyqxmd.com/read/30333908/development-of-parallel-reaction-monitoring-prm-based-quantitative-proteomics-applied-to-her2-positive-breast-cancer
#10
Mathilde Guerin, Anthony Gonçalves, Yves Toiron, Emilie Baudelet, Matthieu Pophillat, Samuel Granjeaud, Patrick Fourquet, William Jacot, Carole Tarpin, Renaud Sabatier, Emilie Agavnian, Pascal Finetti, José Adelaide, Daniel Birnbaum, Christophe Ginestier, Emmanuelle Charafe-Jauffret, Patrice Viens, François Bertucci, Jean-Paul Borg, Luc Camoin
Introduction: treatments targeting the Human Epidermal Growth Factor Receptor 2 (HER2/ERBB2) have improved the natural history of HER2-positive breast cancer. However, except HER2 protein expression and gene amplification, there is no predictive biomarker to guide the HER2-targeted therapies. We developed Parallel reaction monitoring (PRM) a powerful approach, to quantify and evaluate key proteins involved in the HER2 pathway and/or anti-HER2 treatment sensitivity. Results: in BCLs, PRM measurements correlated with western blot immunocytochemistry and transcriptomic data...
September 18, 2018: Oncotarget
https://www.readbyqxmd.com/read/30333757/dyspnea-and-the-varying-pathophysiologic-manifestations-of-chronic-obstructive-pulmonary-disease-evaluated-by-cardiopulmonary-exercise-testing-with-arterial-blood-analysis
#11
Hiroyuki Kagawa, Keisuke Miki, Seigo Kitada, Mari Miki, Kenji Yoshimura, Yohei Oshitani, Kohei Nishida, Nobuhiko Sawa, Kazuyuki Tsujino, Ryoji Maekura
Background: Patients with chronic obstructive pulmonary disease (COPD) show varying mechanisms of exertional dyspnea with different exercise capacities. Methods: To investigate the pathophysiologic conditions related to exertional dyspnea, 294 COPD patients were evaluated using cardiopulmonary exercise testing (CPET) with arterial blood analyses, with the patients classified into two groups according to their exercise limitation: the leg fatigue group ( n = 58) and the dyspnea group ( n = 215). The dyspnea group was further subdivided into four groups based on peak oxygen uptake ( <mml:math xmlns:mml="http://www...
2018: Frontiers in Physiology
https://www.readbyqxmd.com/read/30332375/-skin-diseases-in-africans
#12
REVIEW
Ana Marcos-Pinto, Ana Ortins-Pina, João Borges-Costa
Nowadays, due to the increasingly frequent migratory circuits in Europe and the increment of the migrant population in Portugal, mainly in the Lisbon metropolitan area, it is more and more common to find several dermatological conditions and disorders in Africans seen in our health care system. There are few studies on dermatoses in these populations. It is important to know the biologic and physiologic differences of black skin in order to understand both the pathophysiology and manifestations of dermatoses...
June 6, 2018: Acta Médica Portuguesa
https://www.readbyqxmd.com/read/30329136/adherence-to-a-long-term-physical-activity-and-exercise-program-after-stroke-applied-in-a-randomized-controlled-trial
#13
Mari Gunnes, Birgitta Langhammer, Inger-Lise Aamot, Stian Lydersen, Hege Ihle-Hansen, Bent Indredavik, Kristine H Reneflot, Walburga Schroeter, Torunn Askim
Background: Persistent physical activity is important to maintain motor function across all stages after stroke. Objective: The objective was to investigate adherence to an 18-month physical activity and exercise program. Design: The design was a prospective, longitudinal study including participants with stroke randomly allocated to the intervention-arm of a randomized controlled trial. Methods: The intervention consisted of individualized monthly coaching by a physical therapist who motivated participants to adhere to 30 minutes of daily physical activity and 45 minutes of weekly exercise over 18 months...
October 17, 2018: Physical Therapy
https://www.readbyqxmd.com/read/30329005/-indication-access-and-use-of-medicines-for-chronic-respiratory-diseases-in-brazil-results-from-the-national-survey-on-access-utilization-and-promotion-of-rational-use-of-medicines-in-brazil-pnaum-2014
#14
Lisiane Freitas Leal, Andrea Dâmaso Bertoldi, Ana Maria Baptista Menezes, Rogério Boff Borges, Sotero Serrate Mengue, Marcelo Basso Gazzana, Tatiane da Silva Dal Pizzol
The study aimed to estimate the prevalence of self-reported chronic respiratory diseases and the indication, access to, and use of medicines, as well as their sources, in the Brazilian adult population. Data were analyzed on adults 20 years and older from the National Survey on Access, Utilization, and Promotion of Rational Use of Medicines in Brazil (PNAUM), conducted from September 2013 to February 2014. Prevalence of chronic respiratory diseases was 3% (95%CI: 2.7-3.3). Of these individuals, 58.1% (95%CI: 51...
October 11, 2018: Cadernos de Saúde Pública
https://www.readbyqxmd.com/read/30328975/factors-associated-with-complex-surgical-wounds-in-breast-and-abdomen-a-case-control-observational-study
#15
Josimare Aparecida Otoni Spira, Eline Lima Borges, Patrícia Aparecida Barbosa Silva, Mery Natali Silva Abreu, Antônio Carlos Martins Guedes, José Ferreira Pires-Júnior
OBJECTIVE: to identify factors associated with complex surgical wounds in the breasts and abdomen in outpatients. METHOD: observational case-control study involving 327 patients, distributed into 160 cases (complex surgical wound) and 167 controls (simple surgical wound). Data were extracted from the medical records and a binary logistic regression model was used for analysis, considering a significance level of 5%. RESULTS: the factors associated with greater chance of occurrence of complex surgical wound were 18 to 59 years of age (p = 0...
October 11, 2018: Revista Latino-americana de Enfermagem
https://www.readbyqxmd.com/read/30328937/moderate-endemicity-of-the-human-t-lymphotropic-virus-infection-in-the-metropolitan-region-of-bel%C3%A3-m-par%C3%A3-brazil
#16
Ingrid Christiane Silva, Bruna Teles Pinheiro, Akim Felipe Santos Nobre, Jaciana Lima Coelho, Cássia Cristine Costa Pereira, Louise de Souza Canto Ferreira, Camila Pâmela Santos de Almeida, Maria de Nazaré do Socorro de Almeida Viana, Danilo Souza de Almeida, Jairo Ribeiro Falcão, Yago Costa Vasconcelos Dos Santos, Marcos William Leão de Araújo, Mariza da Silva Borges, Lisandra Duarte Nascimento, Lorena Saldanha Valentim, Jorge Simão do Rosario Casseb, Carlos Araújo da Costa, Maísa Silva de Sousa
INTRODUCTION: The spread of the HTLV infection in families living in the metropolitan area of Belém, Pará, Brazil, and the lack of studies in the general population requires studies to better understand its prevalence in the region. METHODS: An anti-HTLV-1/HTLV-2 antibodies test was carried out on random adults in public places in Belém between November 2014 and November 2015. A proviral DNA test detected if the person was infected, and then a clinical evaluation and an intrafamilial investigation were carried out...
October 11, 2018: Revista Brasileira de Epidemiologia, Brazilian Journal of Epidemiology
https://www.readbyqxmd.com/read/30328936/cardiorespiratory-and-metabolic-determinants-during-moderate-and-high-resistance-exercise-intensities-until-exhaustion-using-dynamic-leg-press-comparison-with-critical-load
#17
V M Arakelian, C L Goulart, R G Mendes, F C Caruso, V Baldissera, R Arena, A Borghi-Silva
The objective of this study was to assess cardiovascular, respiratory, and metabolic responses during a commonly used dynamic leg press resistance exercise until exhaustion (TEx) at different intensities and compare with critical load (CL). This was a prospective, cross-sectional, controlled, and crossover study. Twelve healthy young men (23±2.5 years old) participated. The subjects carried out three bouts of resistance exercise in different percentages of 1 repetition maximum (60, 75, and 90% 1RM) until TEx...
October 11, 2018: Brazilian Journal of Medical and Biological Research, Revista Brasileira de Pesquisas Médicas e Biológicas
https://www.readbyqxmd.com/read/30328916/preservation-of-the-vagus-nerves-in-subtotal-esophagectomy-without-thoracotomy
#18
Eduardo Crema, Júverson Alves Terra Júnior, Marisa Carvalho Borges, Carlos Alfredo Salci Queiroz, Luciana Arantes Soares, Alex Augusto da Silva
PURPOSE: To evaluate the outcome of transhiatal esophagectomy without thoracotomy and with preservation of the vagal trunks for the treatment of advanced megaesophagus. METHODS: Between March 2006 and September 2017, it was performed 136 transhiatal esophagectomies without thoracotomy by laparoscopy, with preservation of the vagus nerves. All patients were evaluated pre and postoperatively for respiratory and nutritional aspects Post operatively, some surgical aspects were evaluated like radiology and endoscopy of the digestive tract...
September 2018: Acta Cirúrgica Brasileira
https://www.readbyqxmd.com/read/30328225/extending-compound-identification-for-molecular-network-using-the-lipidxplorer-database-independent-method-a-proof-of-concept-using-glycoalkaloids-from-solanum-pseudoquina-a-st-hil
#19
Vitor Soares, Rahil Taujale, Rafael Garrett, Antonio Jorge R da Silva, Ricardo M Borges
INTRODUCTION: Molecular networks are now established as the method of choice for tandem mass spectrometry dereplication and similarity-based structure elucidation. Node identification can be used to start the propagation of the structure elucidation of unknown compounds progressively. OBJECTIVE: To demonstrate the capabilities of using the LipidXplorer data results along with molecular networking to identify nodes and aid sequential structure elucidation of unknown compounds...
October 16, 2018: Phytochemical Analysis: PCA
https://www.readbyqxmd.com/read/30327919/an-in-vitro-approach-to-evaluate-the-nutraceutical-value-of-plant-foliage-against-haemonchus-contortus
#20
G S Castañeda-Ramírez, M Rodríguez-Labastida, G I Ortiz-Ocampo, P G González-Pech, J Ventura-Cordero, R Borges-Argáez, J F J Torres-Acosta, C A Sandoval-Castro, C Mathieu
Nutraceutical plants provide nutrients for the animal as well as secondary compounds that can affect the biology and survival of gastrointestinal nematodes (GIN). Current screening of nutraceutical plants is based on in vitro evidence of anthelmintic (AH) activity against different life stages of GIN, but nutritional information is omitted or scarce. This study proposes an integral in vitro screening protocol to identify the nutraceutical value of the foliage from plant species consumed by small ruminants, using Haemonchus contortus as a biological model...
October 16, 2018: Parasitology Research
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