Karan Goswami, Samuel Clarkson, Craig Tipton, Caleb D Phillips, Douglas A Dennis, Brian A Klatt, Michael O'Malley, Eric L Smith, Jeremy Gililland, Christopher E Pelt, Christopher L Peters, Arthur L Malkani, Brian T Palumbo, Steven T Lyons, Thomas L Bernasek, Jon Minter, Nitin Goyal, William Purtill, James F McDonald, Michael B Cross, Hernan A Prieto, Gwo-Chin Lee, Erik N Hansen, Stefano A Bini, Derek T Ward, Neil Zhao, Noam Shohat, Carlos A Higuera, Dennis Nam, Craig J Della Valle, Javad Parvizi
BACKGROUND: Recent advances in high-throughput DNA sequencing technologies have made it possible to characterize the microbial profile in anatomical sites previously assumed to be sterile. We used this approach to explore the microbial composition within joints of osteoarthritic patients. METHODS: This prospective multicenter study recruited 113 patients undergoing hip or knee arthroplasty between 2017 and 2019. Demographics and prior intra-articular injections were noted...
May 16, 2023: Journal of Bone and Joint Surgery. American Volume