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https://www.readbyqxmd.com/read/30533595/culture-negative-periprosthetic-joint-infection-an-update-on-what-to-expect
#1
Timothy L Tan, Michael M Kheir, Noam Shohat, Dean D Tan, Matthew Kheir, Chilung Chen, Javad Parvizi
Background: Culture-negative periprosthetic joint infection (PJI) is a challenging condition to treat. The most appropriate management of culture-negative PJI is not known, and there is immense variability in the treatment outcome of this condition. The purpose of this study was to elucidate the characteristics, outcomes, and risk factors for failure of treatment of culture-negative PJI. Methods: A retrospective review of 219 patients (138 hips and 81 knees) who had undergone surgery for the treatment of culture-negative PJI was performed utilizing a prospectively collected institutional PJI database...
September 25, 2018: JB & JS open access
https://www.readbyqxmd.com/read/30516629/routine-diagnostic-tests-for-periprosthetic-joint-infection-demonstrate-a-high-false-negative-rate-and-are-influenced-by-the-infecting-organism
#2
Michael M Kheir, Timothy L Tan, Noam Shohat, Carol Foltz, Javad Parvizi
BACKGROUND: Current guidelines recommend serum erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) as the first-line testing for evaluation of suspected periprosthetic joint infection, in addition to synovial white blood-cell (WBC) count and polymorphonuclear percentage. However, the sensitivity and other diagnostic measures of these tests using a standardized definition of periprosthetic joint infection and the influence of organisms on these inflammatory markers remain inadequately investigated...
December 5, 2018: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/30444756/acetabular-labral-tears-are-common-in-asymptomatic-contralateral-hips-with-femoroacetabular-impingement
#3
Hamed Vahedi, Arash Aalirezaie, Ibrahim Azboy, Tanine Daryoush, Alisina Shahi, Javad Parvizi
BACKGROUND: The number of patients undergoing hip arthroscopy for labral tears has increased, but labral tears are sometimes seen in asymptomatic patients with femoroacetabular impingement (FAI). The frequency of this finding, however, has not been well characterized nor is the proportion of patients with previously asymptomatic labral tears who may later become symptomatic. QUESTIONS/PURPOSES: The purpose of this study was to determine (1) the prevalence of labral tears and other intraarticular pathology in the asymptomatic contralateral hip of patients undergoing surgery for symptomatic FAI; (2) the likelihood that the asymptomatic hip had become symptomatic at latest followup; and (3) any association between MRI findings and age, sex, and body mass index (BMI) in both symptomatic and asymptomatic sides...
November 5, 2018: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/30361126/a-meta-analysis-comparing-the-direct-anterior-with-other-approaches-in-primary-total-hip-arthroplasty
#4
Fatih Kucukdurmaz, Mohamed Sukeik, Javad Parvizi
BACKGROUND: Proponents of the direct anterior approach (DAA) for THAs suggest earlier recovery with no increased complications whereas opponents suggest higher complication rates. METHODS: We conducted a meta-analysis of randomized controlled trials (RCTs) to compare the outcomes of the DAA versus other surgical approaches in primary THAs. RESULTS: We identified 18 RCTs suitable for detailed extraction of the data. The RCTs included a total of 1661 patients with a mean age of 62 years (range 55-69)...
October 22, 2018: Surgeon: Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland
https://www.readbyqxmd.com/read/30348579/general-assembly-prevention-surgical-site-preparation-proceedings-of-international-consensus-on-orthopedic-infections
#5
Gerald J Akins, Maria Tibau Alberdi, Andrew Beswick, John David Blaha, Joshua Bingham, James Cashman, Antonia Chen, Alexus M Cooper, Gilberto Lara Cotacio, Toni Fraguas, Anil Gambhir, Kirill Gromov, Ernesto Guerra, Gary Hooper, Anton Khlopas, David Kieser, Ianiv Klaber, Richard Kyte, Brett Levine, Michael A Mont, Vasileios Nikolaou, Jorge Nuñez, Soeren Overgaard, Javad Parvizi, Arjun Saxena, Gustavo Sayago, Hossain Shahcheraghi, Nipun Sodhi, Lucian Bogdan Solomon, Yolandi Starczak, Timothy L Tan, Majd Tarabichi, Rafael Tibau Olivan, Petri Virolainen, Michael Wyatt
No abstract text is available yet for this article.
October 19, 2018: Journal of Arthroplasty
https://www.readbyqxmd.com/read/30348578/hip-and-knee-section-treatment-prosthesis-factors-proceedings-of-international-consensus-on-orthopedic-infections
#6
Guillem Bori, Michael Kelly, Daniel Kendoff, Mitchell R Klement, Rafael Llopis, Laurens Manning, Javad Parvizi, Michael J Petrie, Amir Sandifort, Nemandra A Sandiford, Ian Stockley
No abstract text is available yet for this article.
October 19, 2018: Journal of Arthroplasty
https://www.readbyqxmd.com/read/30348569/general-assembly-prevention-blood-conservation-proceedings-of-international-consensus-on-orthopedic-infections
#7
Mandus Akonjom, Andrew Battenberg, David Beverland, Jae-Hyuck Choi, Yale Fillingham, Nicola Gallagher, Seung Beom Han, Woo Young Jang, William Jiranek, Jorge Manrique, Kalin Mihov, Robert Molloy, Michael A Mont, Sumon Nandi, Javad Parvizi, Trisha N Peel, Luis Pulido, Martin Sarungi, Nipun Sodhi, Maria Tibau Alberdi, Rafael Tibau Olivan, David Wallace, Xisheng Weng, Henry Wynn-Jones, Seng Jin Yeo
No abstract text is available yet for this article.
October 19, 2018: Journal of Arthroplasty
https://www.readbyqxmd.com/read/30348567/general-assembly-prevention-antiseptic-irrigation-solution-proceedings-of-international-consensus-on-orthopedic-infections
#8
Ashley Blom, JeoungEun Cho, Andrew Fleischman, Karan Goswami, Constantinos Ketonis, Setor Kunustor, Gabriel Makar, Daniel G Meeker, Rhidian Morgan-Jones, Silvestre Ortega-Peña, Javad Parvizi, Mark Smeltzer, Jeffrey B Stambough, Kenneth Urish, Giorgio P Tonelo Zilotto
No abstract text is available yet for this article.
October 19, 2018: Journal of Arthroplasty
https://www.readbyqxmd.com/read/30348566/hip-and-knee-section-diagnosis-algorithm-proceedings-of-international-consensus-on-orthopedic-infections
#9
Mahmoud Abdel Karim, John Andrawis, Francisco Bengoa, Carlos Bracho, Riccardo Compagnoni, Michael Cross, Jonathan Danoff, Craig J Della Valle, Pedro Foguet, Toni Fraguas, Thorsten Gehrke, Karan Goswami, Ernesto Guerra, Yong-Chan Ha, Ianiv Klaber, Georgios Komnos, Paul Lachiewicz, Christian Lausmann, Brett Levine, Andrea Leyton-Mange, Benjamin A McArthur, Rene Mihalič, Jeroen Neyt, Jorge Nuñez, Carl Nunziato, Javad Parvizi, Carsten Perka, Marie-Jacque Reisener, Cesar H Rocha, Daniel Schweitzer, Faiz Shivji, Noam Shohat, Rafael J Sierra, Linda Suleiman, Timothy L Tan, Julia Vasquez, Derek Ward, Matthias Wolf, Akos Zahar
No abstract text is available yet for this article.
October 19, 2018: Journal of Arthroplasty
https://www.readbyqxmd.com/read/30348557/hip-and-knee-section-outcomes-proceedings-of-international-consensus-on-orthopedic-infections
#10
William P Abblitt, Tiziana Ascione, Stefano Bini, Guillem Bori, Adam C Brekke, Antonia F Chen, Paul M Courtney, Craig J Della Valle, Claudio Diaz-Ledezma, Ayman Ebied, Yale J Fillingham, Thorsten Gehrke, Karan Goswami, George Grammatopoulos, Sameh Marei, Ali Oliashirazi, Javad Parvizi, Gregory Poljowski, Kordo Saeed, Adam J Schwartz, John Segreti, Noam Shohat, Bryan D Springer, Linda I Suleiman, Lee K Swiderek, Timothy L Tan, Chun Hoi Yan, Yi Rong Zeng
No abstract text is available yet for this article.
October 19, 2018: Journal of Arthroplasty
https://www.readbyqxmd.com/read/30343971/hip-and-knee-section-what-is-the-definition-of-a-periprosthetic-joint-infection-pji-of-the-knee-and-the-hip-can-the-same-criteria-be-used-for-both-joints-proceedings-of-international-consensus-on-orthopedic-infections
#11
Noam Shohat, Thomas Bauer, Martin Buttaro, Nicolaas Budhiparama, James Cashman, Craig J Della Valle, Lorenzo Drago, Thorsten Gehrke, Luiz S Marcelino Gomes, Karan Goswami, Nils P Hailer, Seung Beom Han, Carlos Higuera, Yutaka Inaba, Jean-Yves Jenny, Per Kjaersgaard-Andersen, Mel Lee, Adolfo Llinás, Konstantinos Malizos, Michael A Mont, Rhidian Morgan Jones, Javad Parvizi, Patricia Peel, Salvador Rivero-Boschert, Carlo Romano, John Segreti, Alex Soriano, Ricardo Sousa, Mark Spangehl, Timothy L Tan, Rashid Tikhilov, Ibrahim Tuncay, Heinz Winkler, Eivind Witso, Marjan Wouthuyzen-Bakker, Simon Young, Xianlong Zhang, Yixin Zhou, Werner Zimmerli
No abstract text is available yet for this article.
October 22, 2018: Journal of Arthroplasty
https://www.readbyqxmd.com/read/30343969/introduction-proceedings-of-international-consensus-on-orthopedic-infections
#12
EDITORIAL
Javad Parvizi, Thorsten Gehrke, Michael A Mont, John J Callaghan
No abstract text is available yet for this article.
October 22, 2018: Journal of Arthroplasty
https://www.readbyqxmd.com/read/30281077/failure-after-two-stage-exchange-arthroplasty-for-treatment-of-periprosthetic-joint-infection-the-role-of-antibiotics-in-the-cement-spacer
#13
Marjan Wouthuyzen-Bakker, Michael M Kheir, Ignacio Moya, Alexander J Rondon, Matthew Kheir, Luis Lozano, Javad Parvizi, Alex Soriano
Introduction: Failure after a two-stage exchange surgery for periprosthetic joint infections (PJI) is high. Previous studies demonstrated that positive cultures at reimplantation are associated with failure afterwards. The aim of this multicenter study was to define the role of antibiotics in the cement spacer in relation to reimplantation cultures and subsequent failure. Methods: We retrospectively evaluated two-stage exchange procedures between 2000 and 2015. Culture-negative PJIs, cases in whom no cultures were obtained during reimplantation and cases without data on cement spacers were excluded...
October 3, 2018: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/30273960/novel-mutation-in-teneurin-3-found-to-co-segregate-in-all-affecteds-in-a-multi-generation-family-with-developmental-dysplasia-of-the-hip
#14
George Feldman, Dietmar Kappes, Jayati Mookerjee-Basu, Theresa Freeman, Andrzej Fertala, Javad Parvizi
DDH is a debilitating condition characterized by incomplete formation of the acetabulum leading to dislocation of the hip, suboptimal joint function and accelerated wear of the articular cartilage resulting in early onset crippling arthritis of the hip in 20-40 year olds. Current diagnostic tests in newborns using physical manipulation of the femur or ultrasound either under or over-diagnose this condition. Developing an accurate, cost effective diagnostic test is a goal of this study. To better understand the biologic pathways involved in acetabular development, DNA from severely affected individuals in a four generation family that showed inter-generational transmission of the disorder was isolated and whole exome sequenced...
October 1, 2018: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://www.readbyqxmd.com/read/30245124/persistent-wound-drainage-after-total-joint-arthroplasty-a-narrative-review
#15
REVIEW
Frank-Christiaan B M Wagenaar, Claudia A M Löwik, Akos Zahar, Paul C Jutte, Thorsten Gehrke, Javad Parvizi
BACKGROUND: Persistent wound drainage after total joint arthroplasty (TJA) is an important complication with potential substantial adverse consequences, in particular periprosthetic joint infection. METHODS: This review evaluated the available literature regarding several issues in the field of persistent wound drainage after TJA and offers a classification of persistent wound drainage and an algorithmic approach to the decision-making process. RESULTS: Available literature addressing the diagnosis and treatment of persistent wound drainage after TJA is scarce and an evidence-based clinical guideline is lacking...
September 3, 2018: Journal of Arthroplasty
https://www.readbyqxmd.com/read/30187096/blood-loss-and-allogeneic-transfusion-for-surgical-treatment-of-periprosthetic-joint-infection-a-comparison-of-one-vs-two-stage-exchange-total-hip-arthroplasty
#16
Ahmad Shoib Sharqzad, Camila Cavalheiro, Akos Zahar, Christian Lausmann, Thorsten Gehrke, Daniel Kendoff, Javad Parvizi, Mustafa Citak
PURPOSE: The purpose of the current study was to compare the blood loss and the need for allogeneic transfusion after one- and two-stage exchange arthroplasty for periprosthetic joint infection (PJI) of THA. METHODS: We performed a retrospective review of all patients undergoing either one-stage or two-stage septic exchange arthroplasty at two high-volume infection referral centres. The study cohort consists of 90 patients undergoing the two-stage and 184 patients the one-stage exchange arthroplasty...
September 5, 2018: International Orthopaedics
https://www.readbyqxmd.com/read/30150154/two-stage-exchange-arthroplasty-is-a-favorable-treatment-option-upon-diagnosis-of-a-fungal-periprosthetic-joint-infection
#17
Feng-Chih Kuo, Karan Goswami, Noam Shohat, Kier Blevins, Alexander J Rondon, Javad Parvizi
BACKGROUND: This study investigated the prevalence of medical comorbidities, risk factors, and treatment outcomes in patients with fungal periprosthetic joint infection (PJI). METHODS: All patients with fungal PJI treated from 1999 to 2014 were retrospectively identified at a single institution. Demographic data, comorbidity, and surgical variables were obtained from medical records. Patients were followed up for at least 2 years. PJI was diagnosed using the Musculoskeletal Infection Society criteria...
November 2018: Journal of Arthroplasty
https://www.readbyqxmd.com/read/30100137/defining-treatment-success-after-2-stage-exchange-arthroplasty-for-periprosthetic-joint-infection
#18
Timothy L Tan, Karan Goswami, Yale A Fillingham, Noam Shohat, Alexander J Rondon, Javad Parvizi
BACKGROUND: Two-stage exchange arthroplasty remains the preferred surgical treatment method for patients with chronic periprosthetic joint infection (PJI). The success of this procedure is not known exactly as various definitions of success have been used. This study aimed at analyzing the difference in outcome following 2-stage exchange arthroplasty using different definitions for success. METHODS: A retrospective study of 703 patients with PJI who underwent resection arthroplasty and spacer insertion between January 1999 and June 2015 was performed...
November 2018: Journal of Arthroplasty
https://www.readbyqxmd.com/read/30100135/patients-with-infected-total-hip-arthroplasty-undergoing-2-stage-exchange-arthroplasty-experience-massive-blood-loss
#19
Rahul Goel, Patrick Buckley, Emily Sterbis, Javad Parvizi
BACKGROUND: Two-stage exchange arthroplasty is the preferred treatment for chronic periprosthetic joint infection following total hip arthroplasty (THA). These patients are at high risk of substantial blood loss and perioperative blood transfusion. Our study aimed at determining risk factors for blood transfusion during a 2-stage exchange for infected THA. METHODS: Medical records of 297 patients with infected THA who underwent 2-stage exchange arthroplasty from 1997 to 2016 were reviewed...
November 2018: Journal of Arthroplasty
https://www.readbyqxmd.com/read/30100134/diagnosing-periprosthetic-joint-infection-in-inflammatory-arthritis-assumption-is-the-enemy-of-true-understanding
#20
Noam Shohat, Karan Goswami, Yale Fillingham, Timothy L Tan, Tyler Calkins, Craig J Della Valle, Jaiben George, Carlos Higuera, Javad Parvizi
BACKGROUND: Despite concern over the interpretation of serum and synovial fluid tests to screen and diagnose periprosthetic joint infection (PJI) in patients with inflammatory arthritis, only a single study has investigated this area. We aimed to assess accuracy of clinical and laboratory markers for PJI diagnosis in the context of underlying inflammatory arthritis. METHODS: This multicenter study was conducted on total joint arthroplasty patients at 3 different centers between 2001 and 2016...
November 2018: Journal of Arthroplasty
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