Read by QxMD icon Read

Depression pregnancy

Christina Bourne, Laura Kenkel
Women are more likely than men to experience depression throughout the life span. Sex differences in neurochemistry and brain structure, as well as societal factors may contribute to women's increased likelihood of depression. Pharmacological research targeting depression has historically excluded women, leading to a knowledge gap regarding effective antidepressant treatment in women. Antidepressant pharmacokinetics and pharmacodynamics are clearly different in men and women, necessitating a thoughtful approach to their prescription and management...
October 20, 2018: Handbook of Experimental Pharmacology
Sanika Chirwa, Chioma R Nwabuisi, Gwinnett M Ladson, Linda Korley, Janice E Whitty, Robin Atkinson, John T Clark
We hypothesized that poor sleep quality exacerbates glucose intolerance manifested as elevated glycosylated hemoglobin (HbA1c), which increases the risk for gestational diabetes. To test this, 38 pregnant and 22 non-pregnant (age, 18⁻35 years; body-mass index, 20⁻35 kg/m²) otherwise healthy women were enrolled in the study. Sleep quality was assessed during gestational week 24 (pregnant), or outside of the menstrual period (non-pregnant), using qualitative (Pittsburgh Sleep Quality Index) and objective (actigraphic wrist-watch) measures...
October 18, 2018: International Journal of Environmental Research and Public Health
Mandy Mihelic, Alina Morawska, Ania Filus
Fathers are increasingly expected to contribute to their parenting role at the transition to parenthood; however, many fathers experience mental health problems during this time. Parenting support for new fathers is limited, and research often only includes the mothers in intervention studies. Clear evidence for parenting programs for fathers has not yet been established. This study evaluated the effects of a parenting intervention (Baby Triple P) on fathers who were expecting their first baby. The design was a randomized controlled trial comparing Baby Triple P with care as usual over three time points (pregnancy, 10 weeks' postbirth, and 6 months' postbirth) for 112 fathers living in Brisbane, Australia...
October 19, 2018: Infant Mental Health Journal
Alfonso Gutierrez-Zotes, David Gallardo-Pujol, Javier Labad, Rocío Martín-Santos, Luisa García-Esteve, Estel Gelabert, Manuel Jover, Roser Guillamat, Fermín Mayoral, Isolde Gornemann, Francesca Canellas, Mónica Gratacós, Miriam Guitart, Miguel Roca, Javier Costas, Jose Luis Ivorra, Ricard Navinés, Yolanda de Diego, Elisabet Vilella, Julio Sanjuan
INTRODUCTION: The Edinburgh Postnatal Depression Scale (EPDS) is considered the gold standard in screening for postpartum depression. Although the Spanish version has been widely used, its factorial structure has not yet been studied . METHODS: A total of 1,204 women completed the EPDS 32 weeks after delivery. To avoid multiple testing, we split the sample into two halves, randomly drawing two subsamples of 602 participants each. We conducted exploratory factor analysis (EFA), followed by an oblimin rotation with the first sub-sample...
September 2018: Actas Españolas de Psiquiatría
Margie H Davenport, Ashley P McCurdy, Michelle F Mottola, Rachel J Skow, Victoria L Meah, Veronica J Poitras, Alejandra Jaramillo Garcia, Casey E Gray, Nick Barrowman, Laurel Riske, Frances Sobierajski, Marina James, Taniya Nagpal, Andree-Anne Marchand, Megan Nuspl, Linda G Slater, Ruben Barakat, Kristi B Adamo, Gregory A Davies, Stephanie-May Ruchat
OBJECTIVE: To examine the influence of prenatal exercise on depression and anxiety during pregnancy and the postpartum period. DESIGN: Systematic review with random effects meta-analysis and meta-regression. DATA SOURCES: Online databases were searched up to 6 January 2017. STUDY ELIGIBILITY CRITERIA: Studies of all designs were included (except case studies) if they were published in English, Spanish or French and contained information on the Population (pregnant women without contraindication to exercise), Intervention (subjective or objective measures of frequency, intensity, duration, volume or type of exercise), Comparator (no exercise or different frequency, intensity, duration, volume and type of exercise) and Outcome (prenatal or postnatal depression or anxiety)...
November 2018: British Journal of Sports Medicine
Gudrun Winther, Amanda Eskelund, Cecilie Bay Richter, Betina Elfving, Heidi Kaastrup Müller, Sten Lund, Gregers Wegener
The health consequences of maternal obesity during pregnancy are disturbing as they may contribute to mental disorders in subsequent generations. We examine the influence of suboptimal grandmaternal diet on potential metabolic and mental health outcome of grand-progenies with a high-fat diet (HFD) manipulation in adulthood in a rat HFD model. Grandmaternal exposure to HFD exacerbated granddaughter's anxiety-like phenotype. Grandmaternal exposure to HFD led to upregulated corticotropin-releasing hormone receptor 2 mRNA expression involved in the stress axis in the male F2 offspring...
October 15, 2018: Behavioural Brain Research
Jennifer Anne Hall, Geraldine Barrett, Andrew Copas, Tambosi Phiri, Address Malata, Judith Stephenson
BACKGROUND: It is unclear whether unintended pregnancies are associated with adverse outcomes. Data are predominantly from high-income countries and have methodological limitations, calling the findings into question. This research was designed to overcome these limitations and assess the relationships between pregnancy intention and miscarriage, stillbirth, low birthweight, neonatal death and postnatal depression in a low-income country. METHODS: The pregnancy intention of 4,244 pregnant women in Mchinji District, Malawi, was measured using the validated Chichewa version of the London Measure of Unplanned Pregnancy (LMUP)...
2018: PloS One
Vajihe Atashi, Shahnaz Kohan, Zahra Salehi, Kobra Salehi
BACKGROUND: Considering the importance of attachment in child's development and mother's health, various related factors and also lack of necessary information in this regard in our country, the research team decides to conduct this study to evaluate maternal-fetal attachment during pregnancy, its changes and post-partum consequences on mother-infant relationship. This process should be studied during pregnancy and also after delivery so that the effect of related factors and the changes in attachment over time could be determined and comprehensible information about the effective underlying conditions on this issue would be gathered...
October 17, 2018: Reproductive Health
M Torbeyns, S Claes, M Morrens, T Hompes
The prenatal period appears to be important not only for the development of somatic disorders, but also for the development of psychiatric disorders. Stress and the way people deal with this may play an important role.<br/> AIM: To investigate to what extent prenatal maternal psychological stress is a risk factor for the development of affective disorders in the child. and to demonstrate the importance of systematic screening of the psychological well-being of pregnant mothers and mothers with a pregnancy wish...
2018: Tijdschrift Voor Psychiatrie
Sheng Wei, Zifa Li, Meng Ren, Jieqiong Wang, Jie Gao, Yinghui Guo, Kaiyong Xu, Fang Li, Dehao Zhu, Hao Zhang, Rongju Lv, Mingqi Qiao
BACKGROUND: Epidemiological surveys and studies with animal models have established a relationship between maternal stress and affective disorders in their offspring. However, whether maternal depression before pregnancy influences behaviour and related neurobiological mechanisms in the offspring has not been studied. RESULTS: A social defeat stress (SDS) maternal rat model was established using the resident-intruder paradigm with female specific pathogen-free Wistar rats and evaluated with behavioural tests...
October 16, 2018: BMC Neuroscience
Tjitte Verbeek, Loes Quittner, Paul de Cock, Nynke de Groot, Claudi L H Bockting, Huibert Burger
BACKGROUND: Although personality as well as anxiety and depression are recognized as predictors for breastfeeding initiation, evidence of an association of these factors with 6 months' exclusive breastfeeding as recommended by the World Health Organization (WHO) is sparse. PURPOSE: The purpose of this study was to investigate the associations of personality and symptoms of anxiety and depression during and after pregnancy with meeting the WHO recommendation of 6 months' exclusive breastfeeding...
October 15, 2018: Advances in Neonatal Care: Official Journal of the National Association of Neonatal Nurses
Kingi Mochache, Muthoni Mathai, Onesmus Gachuno, Ann Vander Stoep, Manasi Kumar
[This corrects the article DOI: 10.1186/s12991-018-0202-6.].
2018: Annals of General Psychiatry
Thi Kim Ly Do, Thi Thanh Huong Nguyen, Thi Thu Huong Pham
Postpartum depression (PPD) places a burden on maternal health. PPD exerts a negative impact on mothers' health and children's life. The purpose of this research was to identify the prevalence of PPD and the risk factors contributing to PPD. Therefore, a cross-sectional quantitative study was conducted. 116 women were categorized into two groups. One category included new mothers who received scores of Edinburgh Postpartum Depression Scale (EPDS) 12 or more. The other category included mothers who received scores less than 12...
2018: BioMed Research International
Gbolahan Ajibola, Jean Leidner, Gloria K Mayondi, Erik van Widenfelt, Tebogo Madidimalo, Chipo Petlo, Sikhulile Moyo, Mompati Mmalane, Paige L Williams, Adam R Cassidy, Roger Shapiro, Betsy Kammerer, Shahin Lockman
OBJECTIVES: To prospectively assess rates and detailed predictors of morbidity and mortality among HIV-exposed uninfected children and HIV-unexposed children in Botswana in a more recent era. STUDY DESIGN: We enrolled HIV-infected and HIV-uninfected mothers and their children in the prospective observational Tshipidi study at 2 sites (1 city and 1 village) in Botswana from May 2010-July 2012. Live-born children and their mothers were followed for 24 months postpartum...
October 11, 2018: Journal of Pediatrics
Serena B Gumusoglu, Hanna E Stevens
Early disruptions to neurodevelopment are highly relevant to understanding both psychiatric risk and underlying pathophysiology that can be targeted by new treatments. Much convergent evidence from the human literature associates inflammation during pregnancy with later neuropsychiatric disorders in offspring. Preclinical models of prenatal inflammation have been developed to examine the causal maternal physiological and offspring neural mechanisms underlying these findings. Here we review the strengths and limitations of preclinical models used for these purposes and describe selected studies that have shown maternal immune impacts on the brain and behavior of offspring...
August 27, 2018: Biological Psychiatry
Jennifer A Hutcheon, Heidi D Nelson, Reva Stidd, Susan Moskosky, Katherine A Ahrens
BACKGROUND: Currently, no federal guidelines provide recommendations on healthy birth spacing for women in the United States. This systematic review summarises associations between short interpregnancy intervals and adverse maternal outcomes to inform the development of birth spacing recommendations for the United States. METHODS: PubMed/Medline, POPLINE, EMBASE, CINAHL, the Cochrane Database of Systematic Reviews, and a previous systematic review were searched to identify relevant articles published from 1 January 2006 and 1 May 2017...
October 12, 2018: Paediatric and Perinatal Epidemiology
Thirimon Moe-Byrne, Jennifer Valeska Elli Brown, William McGuire
BACKGROUND: Naloxone, a specific opioid antagonist, is available for the treatment of newborn infants with cardiorespiratory or neurological depression that may be due to intrauterine exposure to opioid. It is unclear whether newborn infants may benefit from this therapy and whether naloxone has any harmful effects. OBJECTIVES: To determine the effect of naloxone on the need for and duration of neonatal unit stay in infants of mothers who received opioid analgesia prior to delivery or of mothers who have used a prescribed or non-prescribed opioid during pregnancy...
October 12, 2018: Cochrane Database of Systematic Reviews
Kathryn Wouk, Nisha C Gottfredson, Christine Tucker, Brian W Pence, Samantha Meltzer-Brody, Bharathi Zvara, Karen Grewen, Alison M Stuebe
BACKGROUND: Research shows that individuals can improve mental health by increasing experiences of positive emotions. However, the role of positive emotions in perinatal mental health has not been investigated. This study explored the extent to which positive emotions during infant feeding are associated with maternal depression and anxiety during the first year postpartum. MATERIALS AND METHODS: One hundred and sixty-four women drawn from a longitudinal cohort of mother-infant dyads were followed from the third trimester through 12 months postpartum...
October 10, 2018: Journal of Women's Health
Lea Takács, Jitka Mlíková Seidlerová, Zuzana Štěrbová, Pavel Čepický, Jan Havlíček
Postpartum depression (PPD) affects up to 19% of all mothers, with detrimental effects on both mother and child. The antidepressant and anxiolytic effects of plasma oxytocin are well-documented, but it is still disputable whether synthetic oxytocin (synOT) may protect women against postpartum mood alterations. The current study examined the association between synOT intrapartum and maternal mood postpartum using a prospective design. Two hundred sixty women were screened for depressive symptoms in the last trimester of pregnancy and then again 6 weeks and 9 months postpartum using the Edinburgh Postnatal Depression Scale...
October 10, 2018: Archives of Women's Mental Health
Viviana Vivenzio, Bernardo Nardi, Cesario Bellantuono
Antepartum depression, frequently in comorbidity with anxiety disorders, is a severe psychopathological condition frequently reported in pregnancy and in many cases associated with obstetric and neonatal complications and potential negative consequences on child neurodevelopment. However, the pharmacological treatment of depression, during pregnancy generates a lot of concerns about the risks of such treatment for the fetus development and the neonatal health. The aim of this review is to present a selection of the latest international literature including recent original studies, systematic reviews, meta-analyses and recommendations from the guidelines, both on the risks of an untreated depressive disorders and on the risk of antidepressant therapy during gestation with drugs belonging to the SSRI and SNRI (SRI) class...
September 2018: Recenti Progressi in Medicina
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"