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https://www.readbyqxmd.com/read/30102699/are-two-internal-thoracic-grafts-better-than-one-in-patients-with-chronic-obstructive-lung-disease-analysis-of-387-cases-between-1996-2011
#1
Pevni Dmitry, Aizer Zahi, Mohr Rephael, Nesher Nahum, Kremer Amir, Paz Yosef, Taih Nadav, Ben-Gal Yanai
OBJECTIVES: Bilateral internal thoracic artery (ITA) grafting is associated with improved survival. However, potential survival benefit of using two ITA`s in patients with chronic lung disease (CLD) is questionable due to their increased risk of sternal wound infection (SWI) compared to operations incorporating single ITA (SITA). The purpose of this study is to compare early and long-term outcome of bilateral internal thoracic artery (BITA) grafting to that of grafting with single internal thoracic grafts and vein grafts or radial artery (SITA) in CLD patients with multi-vessels coronary disease...
2018: PloS One
https://www.readbyqxmd.com/read/30079166/performance-based-financing-and-job-satisfaction-in-a-semiurban-health-district-in-cameroon
#2
Léon Jules Owona Manga, André Arsène Bita Fouda, Lucien Mbida, Come Ebana Mvogo
The performance based financing approach is being tested in four regions of Cameroon, including the Littoral region. Our study aimed to study the effects associated with the implementation of the performance based financing approach within the health facilities based in the health district of Edea in the Littoral region in Cameroon. We've carried out a crosssectional analytical study among 178 health personnel from 21 health facilities under PBF-contract within the health district of Edea. We have studied their sociodemographic characteristics, the individual and collective effects resulting from the performance based financing subsidies and the level of job satisfaction...
May 21, 2018: Journal of Public Health in Africa
https://www.readbyqxmd.com/read/30079087/evaluation-of-therapeutic-efficacy-and-safety-of-tranexamic-acid-local-infiltration-in-combination-with-topical-4-hydroquinone-cream-compared-to-topical-4-hydroquinone-cream-alone-in-patients-with-melasma-a-split-face-study
#3
Zohreh Tehranchinia, Bita Saghi, Hoda Rahimi
Introduction: Melasma is an acquired pigmentary disorder characterized by hyperpigmented macules and/or patches affecting sun-exposed skin. Tranexamic acid (TA) can reduce melanin content of epidermis. Thus, we conducted this study to evaluate the efficacy and safety of tranexamic acid local infiltration in combination with topical 4% hydroquinone cream compared to topical 4% hydroquinone cream alone in patients with melasma. Material and Methods: This study was a prospective assessor- and analyst-blind, randomized split-face clinical trial which was performed on patients with bilateral malar epidermal melasma...
2018: Dermatology Research and Practice
https://www.readbyqxmd.com/read/30066171/pain-in-percutaneous-liver-core-needle-biopsy-a-randomized-trial-comparing-the-intercostal-and-subcostal-approaches
#4
Masoud Pezeshki Rad, Bita Abbasi, Negar Morovatdar, Masoomeh Sadeghi, Khaled Hashemi
PURPOSE: Effective pain control during and after percutaneous core needle liver biopsy is important with regard to ethical considerations and patient comfort. In this randomized double-blind study, we compared post-biopsy pain in the patients undergoing liver core-needle biopsy using either subcostal or intercostal approaches. METHODS: All patients referred for ultrasound-guided CNLB between July 2017 and January 2018 to our interventional radiology department were randomized into two groups...
July 31, 2018: Abdominal Radiology
https://www.readbyqxmd.com/read/30052998/does-the-use-of-an-in-situ-or-y-configuration-for-bilateral-internal-thoracic-arteries-influence-long-term-survival-patency-or-repeat-revascularization-in-coronary-bypass-surgery
#5
Rory Kelleher, Damian Gimpel, David J McCormack, Adam El-Gamel
A best evidence topic was constructed according to a structured protocol. The question addressed was whether the configuration of bilateral internal thoracic arteries (BITAs) influences survival, patency or repeat revascularization in patients undergoing coronary artery bypass grafting. Five hundred and seventy-one papers were found using the reported searches, of which 8 represented the best evidence to answer the clinical question. One systematic review, 4 randomized trials and 3 observational studies were selected...
July 20, 2018: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/30049800/intraoperative-lagophthalmos-formula-for-levator-resection-in-congenital-ptosis
#6
Sunah Kang, Ji Won Seo, Chan Joo Ahn, Bita Esmaeli, Ho-Seok Sa
AIM: To calculate a regression formula for intraoperative lagophthalmos to determine the amount of correction in levator resection for mild to moderate congenital ptosis. METHODS: This retrospective study included 38 eyelids from 28 consecutive children with congenital ptosis with levator function of 4 mm or better who showed satisfactory surgical outcomes defined as postoperative margin reflex distance-1 (MRD1) ≥3 mm in each eye and difference in MRD1 ≤1 mm between eyes at 6 months after levator resection...
July 26, 2018: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/30049494/the-fate-of-patients-having-deep-sternal-infection-after-bilateral-internal-thoracic-artery-grafting-in-the-negative-pressure-wound-therapy-era
#7
Giuseppe Gatti, Bernardo Benussi, Davide Brunetti, Alessandro Ceschia, Aldostefano Porcari, Federico Biondi, Gianluca Castaldi, Roberto Luzzati, Gianfranco Sinagra, Aniello Pappalardo
BACKGROUND: Late survival of patients having deep sternal wound infection (DSWI) after bilateral internal thoracic artery (BITA) grafting is largely unexplored. METHODS: Outcomes of 3391 consecutive BITA patients were reviewed retrospectively. Patients with DSWI after surgery (n = 142, 4.2%) were compared with those having no sternal complications (n = 3177). Predictors of DSWI and of mortality during the follow-up period were found with negative-binomial and Cox proportional-hazards regression, respectively...
July 20, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/30041524/liver-transplantation-status-in-iran-a-multi-center-report-on-the-main-transplant-indicators-and-survival-rates
#8
S Ali Malek-Hosseini, Ali Jafarian, Saman Nikeghbalian, Hossein Poustchi, Kamran B Lankarani, Mohsen Nasiri Toosi, Heshmatollah Salahi, Mohsen Dehghani, Ahad Eshraghian, Maryam Sharafkhah, Sareh Eghtesad, Nazgol Motamed-Gorji, Kourosh Kazemi, Javad Salimi, Majid Moini, Alireza Shamsaeefar, Maryam Moini, Masoud Dehghani, Mohammad B Khosravi, Atabak Najafi, Hossein Sattari, Bita Geramizadeh, Mohammad Shafiee, Mohammad N Toutouni, Behnam Sanei, Seyed Mohammadreza Nejatollahi, Alireza Taghavi, Ali Bahador, Mohsen Aliakbarian, Bijan Eghtesad, Reza Malekzadeh
BACKGROUND: Iran's experience with liver transplantation (LT) began more than two decades ago. The purpose of this article is to present the status of LT in Iran, review specific characteristics of the programs, their outcomes, and their growth to become one of the largest LT programs in the world. METHODS: A questionnaire, asking for data on the number of transplants performed and specifics of the recipients and type of donors with focus on indications and outcomes was sent to LT programs...
July 1, 2018: Archives of Iranian Medicine
https://www.readbyqxmd.com/read/30038897/esterification-process-catalyzed-by-zsm-5-zeolite-synthesized-via-modified-hydrothermal-method
#9
Ben Mya Omar, Mohammed Bita, Ilyas Louafi, Assia Djouadi
A modified hydrothermal method for ZSM-5 synthesis was described. The crystals gave a typical pattern (2θ at around 22.5°, 24.0° and 29.8° corresponding to the major peaks of (501, 303 and 503 crystal surfaces)), which indicated that the subnanocrystals could have the primary structure of MFI-type zeolites. the FT-IR spectra of subnanocrystals which have the primary structure of MFI zeolites. Oleic acid methyl ester (OAME) was prepared via a rapid derivatization procedure. the acidic strength is determined by the zeolite crystal structure and the higher esterification rate of ZSM-5 can be attributed to its stronger acidity compared to H2 SO4 , especially after 50 min of reaction...
2018: MethodsX
https://www.readbyqxmd.com/read/30034491/comparing-the-effects-of-progressive-muscle-relaxation-and-physical-activity-on-pregnant-women-s-general-health
#10
Bita Sadeghi, Masoud Sirati-Nir, Zahra Hajimini, Abbas Ebadi, Matin Ali-Asgari
Background: Pregnancy is important because maternal health and well-being directly affects another person's life. This study aimed to compare the effects of progressive muscle relaxation (PMR) and physical activity (PA) on the general health of pregnant women. Materials and Methods: This randomized clinical trial was conducted among 96 primiparous women enrolled in a prenatal clinic in Tehran (Iran) between May 3, 2013 and August 7, 2013. The participants were selected through convenience sampling over 3 weeks and randomly assigned to the PMR, PA, and control groups, comprising 32 participants each...
July 2018: Iranian Journal of Nursing and Midwifery Research
https://www.readbyqxmd.com/read/30032793/the-cancer-genome-atlas-project-an-integrated-molecular-view-of-uveal-melanoma
#11
EDITORIAL
Martine J Jager, Niels J Brouwer, Bita Esmaeli
No abstract text is available yet for this article.
August 2018: Ophthalmology
https://www.readbyqxmd.com/read/30028833/exploration-and-stabilization-of-ras1-mating-zone-a-mechanism-with-positive-and-negative-feedbacks
#12
Bita Khalili, Laura Merlini, Vincent Vincenzetti, Sophie G Martin, Dimitrios Vavylonis
In mating fission yeast cells, sensing and response to extracellular pheromone concentrations occurs through an exploratory Cdc42 patch that stochastically samples the cell cortex before stabilizing towards a mating partner. Active Ras1 (Ras1-GTP), an upstream regulator of Cdc42, and Gap1, the GTPase-activating protein for Ras1, localize at the patch. We developed a reaction-diffusion model of Ras1 patch appearance and disappearance with a positive feedback by a Guanine nucleotide Exchange Factor (GEF) and Gap1 inhibition...
July 2018: PLoS Computational Biology
https://www.readbyqxmd.com/read/30023730/a-method-for-investigation-of-size-dependent-protein-binding-to-nanoholes-using-intrinsic-fluorescence-of-proteins
#13
Bita Malekian, Ivan Maximov, Rainer Timm, Tommy Cedervall, Dan Hessman
We have developed a novel method to study the influence of surface nanotopography on human fibrinogen adsorption at a given surface chemistry. Well-ordered arrays of nanoholes with different diameters down to 45 nm and a depth of 50 nm were fabricated in silicon by electron beam lithography and reactive ion etching. The nanostructured chip was used as a model system to understand the effect of size of the nanoholes on fibrinogen adsorption. Fluorescence imaging, using the intrinsic fluorescence of proteins, was used to characterize the effect of the nanoholes on fibrinogen adsorption...
August 31, 2017: ACS Omega
https://www.readbyqxmd.com/read/30023317/structural-characterization-of-recombinant-streptokinase-following-recovery-from-inclusion-bodies-using-different-chemical-solubilization-treatments
#14
Khadijeh Babaei Sheli, Masoud Ghorbani, Azadeh Hekmat, Bita Soltanian, Alireza Mohammadian, Reza Jalalirad
Circular dichroism (CD) in far-UV region was employed to study the extent of changes occurred in the secondary structures of recombinant streptokinase (rSK), solubilized from inclusion bodies (IBs) by different chemicals and refolded/purified by chromatographic techniques. The secondary structure distribution of rSK, obtained following different chemical solubilization systems, was varied and values in the range of 12.4-14.5% α-helices, 40-51% β-sheets and 35.5-48.3% turns plus residual structures were found...
September 2018: Biotechnology Reports
https://www.readbyqxmd.com/read/30021814/ocular-preservation-with-neoadjuvant-vismodegib-in-patients-with-locally-advanced-periocular-basal-cell-carcinoma
#15
Oded Sagiv, Priyadharsini Nagarajan, Renata Ferrarotto, Thomas J Kandl, Sudip D Thakar, Bonnie S Glisson, Mehmet Altan, Bita Esmaeli
BACKGROUND/AIMS: Locally advanced (T4 per American Joint Committee on Cancer (AJCC) 8th edition) periocular basal cell carcinoma (BCC) can lead to loss of the eye. We report the neoadjuvant use of vismodegib followed by surgery in patients with such lesions with eye preservation as primary goal. METHODS: This retrospective interventional study includes all patients with a T4 periocular BCC (per 8th edition AJCC for eyelid carcinoma) treated by the senior author between 2013 and 2017 with neoadjuvant vismodegib prior to definitive surgery...
July 18, 2018: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/30018877/considerations-and-consequences-of-allowing-dna-sequence-data-as-types-of-fungal-taxa
#16
Juan Carlos Zamora, Måns Svensson, Roland Kirschner, Ibai Olariaga, Svengunnar Ryman, Luis Alberto Parra, József Geml, Anna Rosling, Slavomír Adamčík, Teuvo Ahti, M Catherine Aime, A Martyn Ainsworth, László Albert, Edgardo Albertó, Alberto Altés García, Dmitry Ageev, Reinhard Agerer, Begoña Aguirre-Hudson, Joe Ammirati, Harry Andersson, Claudio Angelini, Vladimír Antonín, Takayuki Aoki, André Aptroot, Didier Argaud, Blanca Imelda Arguello Sosa, Arne Aronsen, Ulf Arup, Bita Asgari, Boris Assyov, Violeta Atienza, Ditte Bandini, João Luís Baptista-Ferreira, Hans-Otto Baral, Tim Baroni, Robert Weingart Barreto, Henry Beker, Ann Bell, Jean-Michel Bellanger, Francesco Bellù, Martin Bemmann, Mika Bendiksby, Egil Bendiksen, Katriina Bendiksen, Lajos Benedek, Anna Bérešová-Guttová, Franz Berger, Reinhard Berndt, Annarosa Bernicchia, Alona Yu Biketova, Enrico Bizio, Curtis Bjork, Teun Boekhout, David Boertmann, Tanja Böhning, Florent Boittin, Carlos G Boluda, Menno W Boomsluiter, Jan Borovička, Tor Erik Brandrud, Uwe Braun, Irwin Brodo, Tatiana Bulyonkova, Harold H Burdsall, Bart Buyck, Ana Rosa Burgaz, Vicent Calatayud, Philippe Callac, Emanuele Campo, Massimo Candusso, Brigitte Capoen, Joaquim Carbó, Matteo Carbone, Rafael F Castañeda-Ruiz, Michael A Castellano, Jie Chen, Philippe Clerc, Giovanni Consiglio, Gilles Corriol, Régis Courtecuisse, Ana Crespo, Cathy Cripps, Pedro W Crous, Gladstone Alves da Silva, Meiriele da Silva, Marjo Dam, Nico Dam, Frank Dämmrich, Kanad Das, Linda Davies, Eske De Crop, Andre De Kesel, Ruben De Lange, Bárbara De Madrignac Bonzi, Thomas Edison E Dela Cruz, Lynn Delgat, Vincent Demoulin, Dennis E Desjardin, Paul Diederich, Bálint Dima, Maria Martha Dios, Pradeep Kumar Divakar, Clovis Douanla-Meli, Brian Douglas, Elisandro Ricardo Drechsler-Santos, Paul S Dyer, Ursula Eberhardt, Damien Ertz, Fernando Esteve-Raventós, Javier Angel Etayo Salazar, Vera Evenson, Guillaume Eyssartier, Edit Farkas, Alain Favre, Anna G Fedosova, Mario Filippa, Péter Finy, Adam Flakus, Simón Fos, Jacques Fournier, André Fraiture, Paolo Franchi, Ana Esperanza Franco Molano, Gernot Friebes, Andreas Frisch, Alan Fryday, Giuliana Furci, Ricardo Galán Márquez, Matteo Garbelotto, Joaquina María García-Martín, Mónica A García Otálora, Dania García Sánchez, Alain Gardiennet, Sigisfredo Garnica, Isaac Garrido Benavent, Genevieve Gates, Alice da Cruz Lima Gerlach, Masoomeh Ghobad-Nejhad, Tatiana B Gibertoni, Tine Grebenc, Irmgard Greilhuber, Bella Grishkan, Johannes Z Groenewald, Martin Grube, Gérald Gruhn, Cécile Gueidan, Gro Gulden, Luis Fp Gusmão, Josef Hafellner, Michel Hairaud, Marek Halama, Nils Hallenberg, Roy E Halling, Karen Hansen, Christoffer Bugge Harder, Jacob Heilmann-Clausen, Stip Helleman, Alain Henriot, Margarita Hernandez-Restrepo, Raphaël Herve, Caroline Hobart, Mascha Hoffmeister, Klaus Høiland, Jan Holec, Håkon Holien, Karen Hughes, Vit Hubka, Seppo Huhtinen, Boris Ivančević, Marian Jagers, Walter Jaklitsch, AnnaElise Jansen, Ruvishika S Jayawardena, Thomas Stjernegaard Jeppesen, Mikael Jeppson, Peter Johnston, Per Magnus Jørgensen, Ingvar Kärnefelt, Liudmila B Kalinina, Gintaras Kantvilas, Mitko Karadelev, Taiga Kasuya, Ivona Kautmanová, Richard W Kerrigan, Martin Kirchmair, Anna Kiyashko, Dániel G Knapp, Henning Knudsen, Kerry Knudsen, Tommy Knutsson, Miroslav Kolařík, Urmas Kõljalg, Alica Košuthová, Attila Koszka, Heikki Kotiranta, Vera Kotkova, Ondřej Koukol, Jiří Kout, Gábor M Kovács, Martin Kříž, Åsa Kruys, Viktor Kučera, Linas Kudzma, Francisco Kuhar, Martin Kukwa, T K Arun Kumar, Vladimír Kunca, Ivana Kušan, Thomas W Kuyper, Carlos Lado, Thomas Læssøe, Patrice Lainé, Ewald Langer, Ellen Larsson, Karl-Henrik Larsson, Gary Laursen, Christian Lechat, Serena Lee, James C Lendemer, Laura Levin, Uwe Lindemann, Håkan Lindström, Xingzhong Liu, Regulo Carlos Llarena Hernandez, Esteve Llop, Csaba Locsmándi, Deborah Jean Lodge, Michael Loizides, László Lőkös, Jennifer Luangsa-Ard, Matthias Lüderitz, Thorsten Lumbsch, Matthias Lutz, Dan Mahoney, Ekaterina Malysheva, Vera Malysheva, Patinjareveettil Manimohan, Yasmina Marin-Felix, Guilhermina Marques, Rubén Martínez-Gil, Guy Marson, Gerardo Mata, P Brandon Matheny, Geir Harald Mathiassen, Neven Matočec, Helmut Mayrhofer, Mehdi Mehrabi, Ireneia Melo, Armin Mešić, Andrew S Methven, Otto Miettinen, Ana M Millanes Romero, Andrew N Miller, James K Mitchell, Roland Moberg, Pierre-Arthur Moreau, Gabriel Moreno, Olga Morozova, Asunción Morte, Lucia Muggia, Guillermo Muñoz González, Leena Myllys, István Nagy, László G Nagy, Maria Alice Neves, Tuomo Niemelä, Pier Luigi Nimis, Nicolas Niveiro, Machiel E Noordeloos, Anders Nordin, Sara Raouia Noumeur, Yuri Novozhilov, Jorinde Nuytinck, Esteri Ohenoja, Patricia Oliveira Fiuza, Alan Orange, Alexander Ordynets, Beatriz Ortiz-Santana, Leticia Pacheco, Ferenc Pál-Fám, Melissa Palacio, Zdeněk Palice, Viktor Papp, Kadri Pärtel, Julia Pawlowska, Aurelia Paz, Ursula Peintner, Shaun Pennycook, Olinto Liparini Pereira, Pablo Pérez Daniëls, Miquel À Pérez-De-Gregorio Capella, Carlos Manuel Pérez Del Amo, Sergio Pérez Gorjón, Sergio Pérez-Ortega, Israel Pérez-Vargas, Brian A Perry, Jens H Petersen, Ronald H Petersen, Donald H Pfister, Chayanard Phukhamsakda, Marcin Piątek, Meike Piepenbring, Raquel Pino-Bodas, Juan Pablo Pinzón Esquivel, Paul Pirot, Eugene S Popov, Orlando Popoff, María Prieto Álvaro, Christian Printzen, Nadezhda Psurtseva, Witoon Purahong, Luis Quijada, Gerhard Rambold, Natalia A Ramírez, Huzefa Raja, Olivier Raspé, Tania Raymundo, Martina Réblová, Yury A Rebriev, Juan de Dios Reyes García, Miguel Ángel Ribes Ripoll, Franck Richard, Mike J Richardson, Víctor J Rico, Gerardo Lucio Robledo, Flavia Rodrigues Barbosa, Cristina Rodriguez-Caycedo, Pamela Rodriguez-Flakus, Anna Ronikier, Luis Rubio Casas, Katerina Rusevska, Günter Saar, Irja Saar, Isabel Salcedo, Sergio M Salcedo Martínez, Carlos A Salvador Montoya, Santiago Sánchez-Ramírez, J Vladimir Sandoval-Sierra, Sergi Santamaria, Josiane Santana Monteiro, Hans Josef Schroers, Barbara Schulz, Geert Schmidt-Stohn, Trond Schumacher, Beatrice Senn-Irlet, Hana Ševčíková, Oleg Shchepin, Takashi Shirouzu, Anton Shiryaev, Klaus Siepe, Esteban B Sir, Mohammad Sohrabi, Karl Soop, Viacheslav Spirin, Toby Spribille, Marc Stadler, Joost Stalpers, Soili Stenroos, Ave Suija, Stellan Sunhede, Sten Svantesson, Sigvard Svensson, Tatyana Yu Svetasheva, Krzysztof Świerkosz, Heidi Tamm, Hatira Taskin, Adrien Taudière, Jan-Olof Tedebrand, Raúl Tena Lahoz, Marina Temina, Arne Thell, Marco Thines, Göran Thor, Holger Thüs, Leif Tibell, Sanja Tibell, Einar Timdal, Zdenko Tkalčec, Tor Tønsberg, Gérard Trichies, Dagmar Triebel, Andrei Tsurykau, Rodham E Tulloss, Veera Tuovinen, Miguel Ulloa Sosa, Carlos Urcelay, François Valade, Ricardo Valenzuela Garza, Pieter van den Boom, Nicolas Van Vooren, Aida M Vasco-Palacios, Jukka Vauras, Juan Manuel Velasco Santos, Else Vellinga, Annemieke Verbeken, Per Vetlesen, Alfredo Vizzini, Hermann Voglmayr, Sergey Volobuev, Wolfgang von Brackel, Elena Voronina, Grit Walther, Roy Watling, Evi Weber, Mats Wedin, Øyvind Weholt, Martin Westberg, Eugene Yurchenko, Petr Zehnálek, Huang Zhang, Mikhail P Zhurbenko, Stefan Ekman
Nomenclatural type definitions are one of the most important concepts in biological nomenclature. Being physical objects that can be re-studied by other researchers, types permanently link taxonomy (an artificial agreement to classify biological diversity) with nomenclature (an artificial agreement to name biological diversity). Two proposals to amend the International Code of Nomenclature for algae, fungi, and plants (ICN), allowing DNA sequences alone (of any region and extent) to serve as types of taxon names for voucherless fungi (mainly putative taxa from environmental DNA sequences), have been submitted to be voted on at the 11th International Mycological Congress (Puerto Rico, July 2018)...
June 2018: IMA Fungus
https://www.readbyqxmd.com/read/30013757/correlation-between-serum-ferritin-level-and-histopathological-disease-severity-in-non-alcoholic-fatty-liver-disease
#17
Seyed Reza Modares Mousavi, Bita Geramizadeh, Amir Anushiravani, Fardad Ejtehadi, Mohammad Hossein Anbardar, Maryam Moini
BACKGROUND Non-alcoholic fatty liver disease (NAFLD) is one of the most common causes of chronic liver disease worldwide. Recently several parameters, such as serum ferritin, have emerged as possible predictors for the severity of NAFLD and insulin sensitivity. We aimed to investigate the value of serum ferritin level as a useful biomarker for the prediction of histopathological disease severity in non-alcoholic steatohepatitis (NASH), the necro-inflammatory form of NAFLD. METHODS This was a prospective cross sectional study in which demographic, clinical, histological, laboratory, and anthropometric data of 30 adult patients with biopsy-proven NAFLD/NASH were analyzed...
April 2018: Middle East Journal of Digestive Diseases
https://www.readbyqxmd.com/read/29998142/brain-single-photon-emission-computed-tomography-scan-spect-and-functional-mri-in-systemic-lupus-erythematosus-patients-with-cognitive-dysfunction-a-systematic-review
#18
REVIEW
Maryam Sahebari, Zahra Rezaieyazdi, Mandana Khodashahi, Bita Abbasi, Fazlollah Ayatollahi
Objectives: Systemic lupus erythematosus (SLE) is an autoimmune disease with a wide range of clinical manifestations. Cognitive dysfunction is one of the manifestations that could present prior to the emergence of any other neuropsychiatric involvements in SLE. Cognitive dysfunction is a subtle condition occurring with a high frequency. However, there is no data on the correlation of cognitive dysfunction with central nervous system (CNS) imaging findings, in particular single-photon emission computed tomography scan (SPECT) and functional MRI...
2018: Asia Oceania Journal of Nuclear Medicine & Biology
https://www.readbyqxmd.com/read/29977033/adults-with-septic-shock-and-extreme-hyperferritinemia-exhibit-pathogenic-immune-variation
#19
Kate F Kernan, Lina Ghaloul-Gonzalez, Bita Shakoory, John A Kellum, Derek C Angus, Joseph A Carcillo
Post-hoc subgroup analysis of the negative trial of interleukin-1β receptor antagonist (IL1RA) for septic shock suggested that patients with features of macrophage activation syndrome (MAS) experienced a 50% relative risk reduction for mortality with treatment. Here we seek a genetic basis for this differential response. From 1341 patients enrolled in the ProCESS trial of early goal directed therapy for septic shock, we selected 6 patients with MAS features and the highest ferritin, for whole exome sequencing (mean 24,030...
July 6, 2018: Genes and Immunity
https://www.readbyqxmd.com/read/29947339/hla-class-i-and-class-ii-genes-distribution-of-the-iranian-sistanis
#20
Mahdi Aminikhah, Mir-Saeed Yekaninejad, Mohammad Hosein Nicknam, Farideh Khosravi, Mehrnaz Naroeinejad, Bita Ansaripour, Batol Moradi, Behrouz Nikbin, Ali Akbar Amirzargar
BACKGROUND: The high polymorphism in the human leukocyte antigen (HLA) genes can be used as an identity of individuals to compare with other populations. This extreme polymorphism in the HLA system is accountable for the differences in alleles and haplotypes among ethnic groups, populations, and the inhabitants of many regions. OBJECTIVE: To define the frequency of HLA alleles and haplotypes among the Sistanis, Sistani/Zaboli population in Iran. METHODS: In this study, genotyping of class I (A, B, C) and class II HLA (DRB1, DQA1, DQB1) loci were determined in 90 unrelated Iraninan Sistani people and the results were compared with 474,892 HLA chromosomes from a diverse worldwide population...
June 2018: Iranian Journal of Immunology: IJI
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